公开(公告)号：US08609898B2

公开(公告)日：2013-12-17

申请号：US13013490

申请日：2011-01-25

申请人： Hirokazu Narita ,  Mikiya Tanaka ,  Kazuko Morisaku

发明人： Hirokazu Narita ,  Mikiya Tanaka ,  Kazuko Morisaku

IPC分类号： C07C233/05 ,  C22B61/00

CPC分类号： C22B11/04 ,  C22B3/001 ,  C22B3/0032 ,  C22B3/10 ,  C22B11/06 ,  Y02P10/234

摘要： The present invention provides a novel separation reagent capable of obtaining a high extraction % of rhodium in a chlorine-based acid solution, which has never existed heretofore, and a method for separating and recovering a platinum group metal using the same. An organic phase composed of an amide-containing tertiary amine separation reagent represented by the structural formula shown below is brought into contact with an acid solution containing a platinum group metal, thereby extracting rhodium, platinum and palladium with the organic phase. Among the metals extracted with the organic phase, rhodium is selectively back-extracted with a highly-concentrated hydrochloric acid solution, while palladium and platinum are back-extracted with a highly-concentrated nitric acid solution: wherein at least one of R1, R2 and R3 represents an amide group represented by: R1 to R3 other than the amide group and R4 to R6 represent a group selected from an optionally branched chain hydrocarbon group of 1 to 18 carbon atoms, an alicyclic hydrocarbon group of 1 to 10 carbon atoms, and an aromatic hydrocarbon group of 1 to 14 carbon atoms.

摘要翻译： 本发明提供了一种能够在迄今为止从未存在的氯系酸溶液中获得高提取率的铑的新型分离试剂，以及使用该分离试剂的铂族金属的分离和回收方法。 将由下述结构式表示的含酰胺的叔胺分离试剂构成的有机相与含有铂族金属的酸溶液接触，由有机相萃取铑，铂和钯。 在有机相提取的金属中，用高度浓缩的盐酸溶液选择性地反萃取铑，钯和铂用高浓度硝酸溶液反萃取：其中R1，R2和 R3表示由除酰胺基以外的R1〜R3表示的酰胺基，R4〜R6表示选自1〜18个任意支链的烃基，1〜10个碳原子的脂环族烃基， 1〜14个碳原子的芳香族烃基。

公开(公告)号：US20070172404A1

公开(公告)日：2007-07-26

申请号：US10590799

申请日：2005-02-23

申请人： Hirokazu Narita ,  Mikiya Tanaka

发明人： Hirokazu Narita ,  Mikiya Tanaka

IPC分类号： C22B11/00 ,  C07C323/39

CPC分类号： C07C323/60 ,  C22B3/0031 ,  C22B11/04 ,  C22B11/048 ,  Y02P10/214 ,  Y02P10/234

摘要： There is provided a novel extractant for palladium capable of improving an extraction speed in comparison with a case of utilizing a DHS being a conventional extractant, and a method for separation and recovery of palladium utilizing the same. The present invention provides a method for obtaining a palladium-containing aqueous solution by bringing an organic phase containing an extractant of a sulfur-containing diamide compound represented by the following structural formula (1): in which R1 and R2 each represent a group selected from a chain hydrocarbon group having 1 to 18 carbon atoms which may be branched, an alicyclic hydrocarbon group having 1 to 10 carbon atoms, and an aromatic hydrocarbon group having 1 to 14 carbon atom, and R3 represents a group represented by {(CH2)nS(CH2)m}L in which n, m and L each represent an integer of from 1 to 4; extracting palladium by the organic phase; and conducting a back-extraction of palladium, extracted by the organic phase, with an aqueous solution of hydrochloric acid containing thiourea.

摘要翻译： 与利用作为常规萃取剂的DHS的情况相比，提供了能够提高萃取速度的钯的新型萃取剂，以及使用该提取剂的钯的分离和回收方法。 本发明提供一种通过使含有由以下结构式（1）表示的含硫二酰胺化合物的萃取剂的有机相来获得含钯水溶液的方法：其中R 1， R 2和R 2各自表示选自可以是支链的碳原子数1〜18的链状烃基，碳原子数1〜10的脂肪族烃基和1〜 14个碳原子，R 3 3表示由{（CH 2）n S（CH 2）2表示的基团， ）其中n，m和L各自表示1〜4的整数; 通过有机相萃取钯; 并用含硫酸的盐酸水溶液进行有机相提取的钯的反提取。

公开(公告)号：US07597863B2

公开(公告)日：2009-10-06

申请号：US10590799

申请日：2005-02-23

申请人： Hirokazu Narita ,  Mikiya Tanaka

发明人： Hirokazu Narita ,  Mikiya Tanaka

IPC分类号： C22B11/00

CPC分类号： C07C323/60 ,  C22B3/0031 ,  C22B11/04 ,  C22B11/048 ,  Y02P10/214 ,  Y02P10/234

摘要： There is provided a novel extractant for palladium capable of improving an extraction speed in comparison with a case of utilizing a DHS being a conventional extractant, and a method for separation and recovery of palladium utilizing the same. The present invention provides a method for obtaining a palladium-containing aqueous solution by bringing an organic phase containing an extractant of a sulfur-containing diamide compound represented by the following structural formula (1): in which R1 and R2 each represent a group selected from a chain hydrocarbon group having 1 to 18 carbon atoms which may be branched, an alicyclic hydrocarbon group having 1 to 10 carbon atoms, and an aromatic hydrocarbon group having 1 to 14 carbon atom, and R3 represents a group represented by {(CH2)nS(CH2)m}L in which n, m and L each represent an integer of from 1 to 4; extracting palladium by the organic phase; and conducting a back-extraction of palladium, extracted by the organic phase, with an aqueous solution of hydrochloric acid containing thiourea.

摘要翻译： 与利用作为常规萃取剂的DHS的情况相比，提供了能够提高萃取速度的钯的新型萃取剂，以及使用该提取剂的钯的分离和回收方法。 本发明提供一种通过使含有由以下结构式（1）表示的含硫二酰胺化合物的萃取剂的有机相获得含钯水溶液的方法：其中R1和R2各自表示选自 可以是支链的碳原子数1〜18的链状烃基，碳原子数1〜10的脂环式烃基和碳原子数1〜14的芳香族烃基，R3表示{（CH2）nS （CH2）m} L，其中n，m和L各自表示1至4的整数; 通过有机相萃取钯; 并用含硫酸的盐酸水溶液进行有机相提取的钯的反提取。

公开(公告)号：US07918918B2

公开(公告)日：2011-04-05

申请号：US12318824

申请日：2009-01-09

申请人： Hirokazu Narita ,  Mikiya Tanaka ,  Ken Tamura

发明人： Hirokazu Narita ,  Mikiya Tanaka ,  Ken Tamura

IPC分类号： C22B11/00 ,  C01G55/00 ,  C07C323/41

CPC分类号： C07C323/60 ,  C22B3/0008 ,  C22B3/10 ,  C22B7/007 ,  C22B11/048 ,  Y02P10/214 ,  Y02P10/234

摘要： Provided is a novel extractant for palladium capable of improving an extraction rate compared to the conventional extractant, DHS, and also capable of back-extracting palladium using an ammonia solution, and a method of separating and recovering palladium using the novel extractant. The present invention provides a method for obtaining an aqueous solution containing palladium only by: bringing an acidic aqueous solution containing at least palladium into contact with an organic solution containing a sulfide-containing monoamide as an active integredient represented by the following structural formula (I), where R1, R2, and R3 each represent a group selected from a chain hydrocarbon group having 1 to 18 carbon atoms which may be branched, an alicyclic hydrocarbon group having 1 to 10 carbon atoms, and an aromatic hydrocarbon group having 1 to 14 carbon atoms, and n represents an integer of 1 to 4; extracting palladium into the organic solution; and conducting the back-extraction of the palladium extracted in the organic solution to an aqueous solution using an ammonia solution.

摘要翻译： 提供了一种新型的能够提高萃取速率的钯萃取剂，与常规萃取剂DHS相比，并且还能够使用氨溶液反萃取钯，以及使用新的萃取剂分离和回收钯的方法。 本发明提供一种获得含钯水溶液的方法，其方法是：使至少含有钯的酸性水溶液与含有硫化物的单酰胺作为活性成分的有机溶液接触，所述有机溶液为下述结构式（I）所示的活性成分， 其中R 1，R 2和R 3各自表示选自可具有支链的碳原子数1〜18的链状烃基，碳原子数1〜10的脂环族烃基和碳原子数1〜14的芳香族烃基 原子，n表示1〜4的整数。 将钯提取到有机溶液中; 并使用氨溶液将在有机溶液中提取的钯进行背萃取至水溶液。

公开(公告)号：US20090178513A1

公开(公告)日：2009-07-16

申请号：US12318824

申请日：2009-01-09

申请人： Hirokazu Narita ,  Mikiya Tanaka ,  Ken Tamura

发明人： Hirokazu Narita ,  Mikiya Tanaka ,  Ken Tamura

IPC分类号： C07C233/05 ,  C07C233/65 ,  C22B11/00

CPC分类号： C07C323/60 ,  C22B3/0008 ,  C22B3/10 ,  C22B7/007 ,  C22B11/048 ,  Y02P10/214 ,  Y02P10/234

摘要： Provided is a novel extractant for palladium capable of improving an extraction rate compared to the conventional extractant, DHS, and also capable of back-extracting palladium using an ammonia solution, and a method of separating and recovering palladium using the novel extractant. The present invention provides a method for obtaining an aqueous solution containing palladium only by: bringing an acidic aqueous solution containing at least palladium into contact with an organic solution containing a sulfide-containing monoamide as an active integredient represented by the following structural formula (I), where R1, R2, and R3 each represent a group selected from a chain hydrocarbon group having 1 to 18 carbon atoms which may be branched, an alicyclic hydrocarbon group having 1 to 10 carbon atoms, and an aromatic hydrocarbon group having 1 to 14 carbon atoms, and n represents an integer of 1 to 4; extracting palladium into the organic solution; and conducting the back-extraction of the palladium extracted in the organic solution to an aqueous solution using an ammonia solution,

摘要翻译： 提供了一种新型的能够提高萃取速率的钯萃取剂，与常规萃取剂DHS相比，并且还能够使用氨溶液反萃取钯，以及使用新的萃取剂分离和回收钯的方法。 本发明提供一种获得含钯水溶液的方法，其方法是：使至少含有钯的酸性水溶液与含有硫化物的单酰胺作为活性成分的有机溶液接触，所述有机溶液为下述结构式（I）所示的活性成分， 其中R 1，R 2和R 3各自表示选自可具有支链的碳原子数1〜18的链状烃基，碳原子数1〜10的脂环族烃基和碳原子数1〜14的芳香族烃基 原子，n表示1〜4的整数。 将钯提取到有机溶液中; 并使用氨溶液将在有机溶液中提取的钯进行背萃取至水溶液，

公开(公告)号：US5236950A

公开(公告)日：1993-08-17

申请号：US311945

申请日：1989-02-17

申请人： Hajime Aoyama ,  Satoshi Ono ,  Osamu Oohashi ,  Hirokazu Narita ,  Shuntaro Takano

发明人： Hajime Aoyama ,  Satoshi Ono ,  Osamu Oohashi ,  Hirokazu Narita ,  Shuntaro Takano

IPC分类号： A61K8/33 ,  A61K8/34 ,  A61K8/37 ,  A61K8/67 ,  A61Q7/00 ,  C07C69/00 ,  C07D213/79

CPC分类号： A61K8/37 ,  A61K8/33 ,  A61K8/342 ,  A61K8/375 ,  A61K8/675 ,  A61Q7/00

摘要： This invention relates to a hair-restorer comprising, as an active ingredient, (a) an acyclic branched higher aliphatic hydrocarbon of 20 carbon atoms which may be substituted with hydroxyl group or acyloxy group, or (b) an acyclic branched carboxylic acid of 20 carbon atoms or its derivative and to a process for hair growth.

摘要翻译： 本发明涉及一种毛发还原剂，其包含作为活性成分的（a）可被羟基或酰氧基取代的20个碳原子的无环支链高级脂族烃，或（b）20个无环支链羧酸 碳原子或其衍生物和毛发生长过程。

公开(公告)号：US5968935A

公开(公告)日：1999-10-19

申请号：US1650

申请日：1997-12-31

申请人： Satoshi Ono ,  Mutsuko Maekawa ,  Kazunari Hirata ,  Hirokazu Narita

发明人： Satoshi Ono ,  Mutsuko Maekawa ,  Kazunari Hirata ,  Hirokazu Narita

IPC分类号： C07C217/10 ,  C07D307/79 ,  C07D333/54 ,  C07D409/12 ,  C07D453/02 ,  C07D471/08 ,  A61K31/535 ,  A61K31/40 ,  A61K31/44 ,  A61K31/495

CPC分类号： C07D307/79 ,  C07C217/10 ,  C07D333/54 ,  C07D409/12 ,  C07D453/02 ,  C07D471/08 ,  Y02P20/55

摘要： A 1,2-ethanediol derivative represented by the general formula [I] or its salt: ##STR1## has a NGF activity-potentiating effect and is useful as a remedy for various diseases caused by degeneration of central nervous system or peripheral nervous system such as senile dementia of Alzheimer type, Huntington's chorea, various neuropathies, Riley-Day syndrome, traumatic nerve injury, amyotrophic lateral sclerosis (ALS) and the like.

公开(公告)号：US5922721A

公开(公告)日：1999-07-13

申请号：US001656

申请日：1997-12-31

申请人： Satoshi Ono ,  Mutsuko Maekawa ,  Kazunari Hirata ,  Hirokazu Narita

发明人： Satoshi Ono ,  Mutsuko Maekawa ,  Kazunari Hirata ,  Hirokazu Narita

IPC分类号： C07C217/10 ,  C07D307/79 ,  C07D333/54 ,  C07D409/12 ,  C07D453/02 ,  C07D471/08 ,  A61K31/495 ,  A61K31/415 ,  A61K31/44 ,  A61K31/505

CPC分类号： C07D307/79 ,  C07C217/10 ,  C07D333/54 ,  C07D409/12 ,  C07D453/02 ,  C07D471/08 ,  Y02P20/55

摘要： A 1,2-ethanediol derivative represented by the general formula �I! or its salt: ##STR1## has a NGF activity-potentiating effect and is useful as a remedy for various diseases caused by degeneration of central nervous system or peripheral nervous system such as senile dementia of Alzheimer type, Huntington's chorea, various neuropathies, Riley-Day syndrome, traumatic nerve injury, amyotrophic lateral sclerosis (ALS) and the like.

公开(公告)号：US5807887A

公开(公告)日：1998-09-15

申请号：US809407

申请日：1997-04-23

申请人： Satoshi Ono ,  Mutsuko Maekawa ,  Kazunari Hirata ,  Hirokazu Narita

发明人： Satoshi Ono ,  Mutsuko Maekawa ,  Kazunari Hirata ,  Hirokazu Narita

IPC分类号： C07C217/10 ,  C07D307/79 ,  C07D333/54 ,  C07D409/12 ,  C07D453/02 ,  C07D471/08 ,  A61K31/38 ,  A61K31/34

CPC分类号： C07D307/79 ,  C07C217/10 ,  C07D333/54 ,  C07D409/12 ,  C07D453/02 ,  C07D471/08 ,  Y02P20/55

摘要： A 1,2-ethanediol derivative represented by the general formula �I! or its salt: ##STR1## has a NGF activity-potentiating effect and is useful as a remedy for various diseases caused by degeneration of central nervous system or peripheral nervous system such as senile dementia of Alzheimer type, Huntington's chorea, various neuropathies, Riley-Day syndrome, traumatic nerve injury, amyotrophic lateral sclerosis (ALS) and the like.

摘要翻译： PCT No.PCT / JP95 / 02162 Sec。 371日期1997年4月23日 102（e）日期1997年4月23日PCT提交1995年10月20日PCT公布。 出版物WO96 / 日期：1996年5月2日由通式[I]表示的1,2-乙二醇衍生物或其盐： [I]具有NGF活性增强作用，可用作由中枢性变性引起的各种疾病的补救 神经系统或周围神经系统，例如老年痴呆型老年痴呆，亨廷顿舞蹈病，各种神经病，莱利日综合征，创伤神经损伤，肌萎缩性侧索硬化（ALS）等。

公开(公告)号：US5719150A

公开(公告)日：1998-02-17

申请号：US749143

申请日：1996-11-14

申请人： Satoshi Ono ,  Tetsuo Yamafuji ,  Hisaaki Chaki ,  Mutsuko Maekawa ,  Yozo Todo ,  Hirokazu Narita

发明人： Satoshi Ono ,  Tetsuo Yamafuji ,  Hisaaki Chaki ,  Mutsuko Maekawa ,  Yozo Todo ,  Hirokazu Narita

IPC分类号： C07C217/10 ,  C07C217/76 ,  C07C229/12 ,  C07C233/18 ,  C07C271/44 ,  C07C271/46 ,  C07C271/58 ,  C07C311/08 ,  C07C311/21 ,  C07C317/22 ,  C07C323/19 ,  C07D207/08 ,  C07D207/14 ,  C07D207/16 ,  C07D207/22 ,  C07D207/26 ,  C07D207/27 ,  C07D207/28 ,  C07D209/08 ,  C07D209/12 ,  C07D209/32 ,  C07D209/34 ,  C07D211/14 ,  C07D211/22 ,  C07D211/32 ,  C07D211/42 ,  C07D211/44 ,  C07D211/46 ,  C07D211/70 ,  C07D211/74 ,  C07D213/26 ,  C07D213/30 ,  C07D213/61 ,  C07D213/64 ,  C07D213/74 ,  C07D213/82 ,  C07D215/14 ,  C07D215/22 ,  C07D215/227 ,  C07D217/04 ,  C07D233/54 ,  C07D235/06 ,  C07D239/42 ,  C07D241/04 ,  C07D241/42 ,  C07D259/00 ,  C07D265/30 ,  C07D277/24 ,  C07D277/62 ,  C07D277/64 ,  C07D279/12 ,  C07D295/088 ,  C07D295/092 ,  C07D307/42 ,  C07D307/79 ,  C07D307/80 ,  C07D309/12 ,  C07D317/54 ,  C07D319/18 ,  C07D333/16 ,  C07D333/28 ,  C07D333/44 ,  C07D333/54 ,  C07D333/56 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D453/02 ,  C07D521/00 ,  A61K31/44 ,  A61K31/135 ,  A61K31/415 ,  A61K31/535

CPC分类号： C07C217/10 ,  C07C217/76 ,  C07C229/12 ,  C07C233/18 ,  C07C271/44 ,  C07C271/46 ,  C07C271/58 ,  C07C311/08 ,  C07C311/21 ,  C07C317/22 ,  C07C323/19 ,  C07D207/08 ,  C07D207/14 ,  C07D207/16 ,  C07D207/22 ,  C07D207/27 ,  C07D207/28 ,  C07D209/08 ,  C07D209/12 ,  C07D209/32 ,  C07D209/34 ,  C07D211/14 ,  C07D211/22 ,  C07D211/32 ,  C07D211/42 ,  C07D211/44 ,  C07D211/46 ,  C07D211/70 ,  C07D211/74 ,  C07D213/26 ,  C07D213/30 ,  C07D213/61 ,  C07D213/64 ,  C07D213/74 ,  C07D213/82 ,  C07D215/14 ,  C07D215/227 ,  C07D217/04 ,  C07D231/12 ,  C07D233/56 ,  C07D233/64 ,  C07D235/06 ,  C07D239/42 ,  C07D241/04 ,  C07D241/42 ,  C07D249/08 ,  C07D259/00 ,  C07D265/30 ,  C07D277/24 ,  C07D277/62 ,  C07D277/64 ,  C07D279/12 ,  C07D295/088 ,  C07D307/42 ,  C07D307/79 ,  C07D307/80 ,  C07D309/12 ,  C07D317/54 ,  C07D319/18 ,  C07D333/16 ,  C07D333/28 ,  C07D333/44 ,  C07D333/54 ,  C07D333/56 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/10 ,  C07D413/12 ,  C07D453/02 ,  C07C2101/02 ,  C07C2101/08 ,  C07C2101/10 ,  C07C2102/08 ,  C07C2102/10

摘要： This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebrovascular dementia, senile dementia, Alzheimer's dementia, sequelae of ischemic encephalopathy and cerebral apoplexy.