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    Method for promoting carnitine palmitoyltransferase activity using green coffee bean extract
    3.
    发明授权
    Method for promoting carnitine palmitoyltransferase activity using green coffee bean extract 有权
    使用绿咖啡豆提取物促进肉碱棕榈酰转移酶活性的方法

    公开(公告)号：US08802164B2

    公开(公告)日：2014-08-12

    申请号：US13038513

    申请日：2011-03-02

    申请人： Hiroshi Shimoda ,  Michio Aitani ,  Tomoko Sugishita ,  Tadashi Okada ,  Hiromichi Murai ,  Emi Yamada

    发明人： Hiroshi Shimoda ,  Michio Aitani ,  Tomoko Sugishita ,  Tadashi Okada ,  Hiromichi Murai ,  Emi Yamada

    IPC分类号： A61K36/74

    CPC分类号： A61Q19/00 ,  A23F5/02 ,  A61K8/97 ,  A61K36/74 ,  A61Q19/06

    摘要： (PROBLEMS) To provide a highly safe dietetic composition originating in green coffee beans by which excellent dietetic effects can be obtained and which contributes to the prevention and treatment of life style-related diseases such as diabetes. (MEANS FOR SOLVING PROBLEMS) A dietetic composition characterized by comprising, as the active ingredient, a polar solvent extract of defatted green coffee beans. It is preferable that the above-described polar solvent extract is an extract obtained by using water-containing ethanol, still preferably water-containing ethanol having an ethanol concentration of from 40 to 90% (wt/wt). It is preferable that the above-described defatted green coffee beans are those obtained by extracting green coffee beans with N-hexane to thereby separate oily components therefrom. It is recommended to combine the above-described dietetic composition with one or more members selected from among salacia extract, evening primrose extract, sesamine and garcinia. This dietetic composition is usable as a material for foods, drinks, drugs, or skin preparations for external use.

    摘要翻译： （问题）提供源自绿咖啡豆的高度安全的饮食组合，通过该饮食组合可以获得优异的饮食效果，并且有助于预防和治疗诸如糖尿病的生活方式相关疾病。 （解决问题的手段）一种饮食组合物，其特征在于，含有脱脂生咖啡豆的极性溶剂提取物作为活性成分。 优选上述极性溶剂提取物是通过使用含水乙醇，更优选乙醇浓度为40〜90％（wt / wt）的含水乙醇得到的提取物。 优选上述脱脂生咖啡豆是通过用N-己烷萃取生咖啡豆而得到的咖啡豆，从而分离出油性成分。 建议将上述饮食组合物与选自沙拉提取物，月见草提取物，芝麻素和藤黄的一种或多种组合物组合。 这种饮食组合物可用作食品，饮料，药物或外用皮肤制剂的材料。

    Dietetic composition
    4.
    发明申请
    Dietetic composition 审中-公开
    饮食组成

    公开(公告)号：US20090274777A1

    公开(公告)日：2009-11-05

    申请号：US10569970

    申请日：2004-10-05

    申请人： Hiroshi Shimoda ,  Michio Aitani ,  Tomoko Sugishita ,  Tadashi Okada ,  Hiromichi Murai ,  Emi Yamada

    发明人： Hiroshi Shimoda ,  Michio Aitani ,  Tomoko Sugishita ,  Tadashi Okada ,  Hiromichi Murai ,  Emi Yamada

    IPC分类号： A61K36/74 ,  A61P3/04

    CPC分类号： A61Q19/00 ,  A23F5/02 ,  A61K8/97 ,  A61K36/74 ,  A61Q19/06

    摘要： (Problems) To provide a highly safe dietetic composition originating in green coffee beans by which excellent dietetic effects can be obtained and which contributes to the prevention and treatment of life style-related diseases such as diabetes.(Means for Solving Problems) A dietetic composition characterized by comprising, as the active ingredient, a polar solvent extract of defatted green coffee beans. It is preferable that the above-described polar solvent extract is an extract obtained by using water-containing ethanol, still preferably water-containing ethanol having an ethanol concentration of from 40 to 90% (wt/wt). It is preferable that the above-described defatted green coffee beans are those obtained by extracting green coffee beans with N-hexane to thereby separate oily components therefrom. It is recommended to combine the above-described dietetic composition with one or more members selected from among salacia extract, evening primrose extract, sesamine and garcinia. This dietetic composition is usable as a material for foods, drinks, drugs, or skin preparations for external use.

    摘要翻译： （问题）提供源自绿咖啡豆的高度安全的饮食组合，通过该饮食组合可以获得优异的饮食效果，并且有助于预防和治疗诸如糖尿病的生活方式相关疾病。 （解决问题的手段）一种饮食组合物，其特征在于，含有脱脂生咖啡豆的极性溶剂提取物作为活性成分。 优选上述极性溶剂提取物是通过使用含水乙醇，更优选乙醇浓度为40〜90％（wt / wt）的含水乙醇得到的提取物。 优选上述脱脂生咖啡豆是通过用N-己烷萃取生咖啡豆而得到的咖啡豆，从而分离出油性成分。 建议将上述饮食组合物与选自沙拉提取物，月见草提取物，芝麻素和藤黄的一种或多种组合物组合。 这种饮食组合物可用作食品，饮料，药物或外用皮肤制剂的材料。

    AGE PRODUCTION INHIBITOR
    5.
    发明申请
    AGE PRODUCTION INHIBITOR 审中-公开
    年龄生产抑制剂

    公开(公告)号：US20130196937A1

    公开(公告)日：2013-08-01

    申请号：US13576433

    申请日：2011-02-10

    申请人： Hiroshi Shimoda ,  Takashi Watanabe ,  Hiromichi Murai ,  Masayuki Yoshikawa

    发明人： Hiroshi Shimoda ,  Takashi Watanabe ,  Hiromichi Murai ,  Masayuki Yoshikawa

    IPC分类号： A61K31/7048 ,  A61Q19/08 ,  A61K8/60

    CPC分类号： A61K36/736 ,  A23C9/13 ,  A23C2240/15 ,  A23G3/36 ,  A23G4/06 ,  A23L33/105 ,  A61K8/602 ,  A61K8/97 ,  A61K31/7024 ,  A61K31/7028 ,  A61K31/7032 ,  A61K31/7048 ,  A61K36/73 ,  A61K2236/30 ,  A61Q19/08 ,  C07H13/04 ,  C07H17/07

    摘要： Disclosed is an AGE production inhibitor or the like, which effectively inhibits the production of an advanced glycation end product (AGE), while having improved biological safety. Specifically disclosed is an AGE production inhibitor or the like, which contains en extract of cherry tree (preferably blossoms or leaves thereof) and/or a processed product of the extract as an active substance. The AGE production inhibitor or the like contains, as an active substance, at least one compound that is selected from among 1-O-(E)-Caffeoyl-β-D-glucopyranoside, 1-O-(E)-Coumaroyl-β-D-glucopyranoside, 1-O-(E)-Cinnamoyl-β-D-glucopyranoside, Kaempferol 3-O-β-D-glucopyranoside, Quercetin 3-O-β-D-glucopyranoside, Kaempferol 3-O-(6″-malony)-β-D-glucopyranoside, and Quercetin 3-O-(6″-malony)-β-D-glucopyranoside.

    摘要翻译： 公开了AGE生产抑制剂等，其有效地抑制了晚期糖基化终产物（AGE）的生产，同时具有改善的生物安全性。 具体公开的是AGE生产抑制剂等，其含有樱桃树（优选花朵或其叶）的提取物和/或作为活性物质的提取物的加工产物。 AGE生产抑制剂等含有至少一种选自1-O-（E） - 酰基-β-D-吡喃葡萄糖苷，1-O-（E） - 磺基酰基-β-D-吡喃葡萄糖苷的化合物作为活性物质 D-吡喃葡萄糖苷，1-O-（E） - 肉豆蔻基-β-D-吡喃葡萄糖苷，山奈酚3-O-β-D-吡喃葡萄糖苷，槲皮素3-O-β-D-吡喃葡萄糖苷，山奈酚3-O- ' - 马来酸）-β-D-吡喃葡萄糖苷和槲皮素3-O-（6“ - 苹果酸）-β-D-吡喃葡萄糖苷。

    Process for producing membrane/ electrode assembly for polymer electrolyte fuel cells
    6.
    发明授权
    Process for producing membrane/ electrode assembly for polymer electrolyte fuel cells 有权
    用于生产聚合物电解质燃料电池的膜/电极组件的方法

    公开(公告)号：US08999434B2

    公开(公告)日：2015-04-07

    申请号：US11626534

    申请日：2007-01-24

    申请人： Hiroshi Shimoda ,  Hirokazu Wakabayashi ,  Shinji Kinoshita ,  Toshihiro Tanuma ,  Hideki Nakagawa

    发明人： Hiroshi Shimoda ,  Hirokazu Wakabayashi ,  Shinji Kinoshita ,  Toshihiro Tanuma ,  Hideki Nakagawa

    IPC分类号： B05D5/12 ,  B29C65/00 ,  B32B37/00 ,  H01M8/02 ,  H01M8/10

    CPC分类号： H01M8/1004 ,  H01M8/0245 ,  Y02E60/523

    摘要： A process is provided whereby a membrane/electrode assembly for polymer electrolyte fuel cells whereby a high output voltage is obtainable within a wide range of current densities.A process for producing a membrane/electrode assembly 1 comprising a first electrode 10 having a first catalyst layer 12 and a first gas diffusion layer 14, a second electrode 20 having a second catalyst layer 22 and a second gas diffusion layer 24, and an electrolyte membrane 30, wherein the first gas diffusion layer 14, a first intermediate having the first catalyst layer 12 formed on the surface of the electrolyte membrane 30 by coating followed by annealing, and a second intermediate having the second catalyst layer 22 formed on the surface of the second gas diffusion layer 24 by coating, are bonded, so that the first catalyst layer 12 is located between the first gas diffusion layer 14 and the electrolyte membrane 30, and the second catalyst layer 22 is located between the second gas diffusion layer 24 and the electrolyte membrane 30.

    摘要翻译： 提供了一种方法，由此能够在宽的电流密度范围内获得高输出电压的聚合物电解质燃料电池的膜/电极组件。 包括具有第一催化剂层12和第一气体扩散层14的第一电极10，具有第二催化剂层22和第二气体扩散层24的第二电极20以及电解质 膜30，其中第一气体扩散层14，具有通过涂覆退火而形成在电解质膜30的表面上的第一催化剂层12的第一中间体，以及形成在第二催化剂层22的表面上的第二中间体 通过涂布将第二气体扩散层24接合，使得第一催化剂层12位于第一气体扩散层14和电解质膜30之间，第二催化剂层22位于第二气体扩散层24和 电解质膜30。

    Process for forming catalyst layer, and process for producing membrane/electrode assembly for polymer electrolyte fuel cell
    7.
    发明授权
    Process for forming catalyst layer, and process for producing membrane/electrode assembly for polymer electrolyte fuel cell 有权
    用于形成催化剂层的方法，以及用于生产聚合物电解质燃料电池的膜/电极组件的方法

    公开(公告)号：US08221919B2

    公开(公告)日：2012-07-17

    申请号：US12481261

    申请日：2009-06-09

    申请人： Hiroshi Shimoda ,  Shinji Kinoshita ,  Toshihiro Tanuma ,  Seigo Kotera

    发明人： Hiroshi Shimoda ,  Shinji Kinoshita ,  Toshihiro Tanuma ,  Seigo Kotera

    IPC分类号： H01M4/80 ,  H01M8/10 ,  H01M4/02

    CPC分类号： H01M4/8882 ,  H01M4/8605 ,  H01M4/8807 ,  H01M4/8814 ,  H01M4/8828 ,  H01M8/1007 ,  Y02P70/56

    摘要： In the production of a membrane/electrode assembly 10, a first catalyst layer 22 (a second catalyst layer 34) is formed by a process comprising steps (a) and (b). (a) A step of applying a coating fluid comprising a catalyst and an ion-exchange resin, on a substrate to form a coating fluid layer. (b) A step of disposing a reinforcing layer 24 (34) on the coating fluid layer formed in the step (a) and then, drying the coating fluid layer to form a first catalyst layer 22 (a second catalyst layer 34) The process provides a catalyst layer whereby defects such as cracks are scarcely formed in the catalyst layer, and the bond strength is high at the interface between the catalyst layer and a reinforcing layer and at the interface between the catalyst layer and a polymer electrolyte membrane.

    摘要翻译： 在制造膜/电极组件10时，通过包括步骤（a）和（b）的方法形成第一催化剂层22（第二催化剂层34）。 （a）将包含催化剂和离子交换树脂的涂布液涂布在基材上以形成涂布液层的工序。 （b）在步骤（a）中形成的涂布液层上设置增强层24（34）的步骤，然后干燥涂布液层以形成第一催化剂层22（第二催化剂层34） 提供了催化剂层，其中在催化剂层中几乎不形成诸如裂纹的缺陷，并且在催化剂层和增强层之间以及催化剂层和聚合物电解质膜之间的界面处的结合强度高。

    METHOD FOR FORMING DEPOSITED FILM AND PHOTOVOLTAIC ELEMENT
    8.
    发明申请
    METHOD FOR FORMING DEPOSITED FILM AND PHOTOVOLTAIC ELEMENT 有权
    形成沉积膜和光伏元件的方法

    公开(公告)号：US20080096305A1

    公开(公告)日：2008-04-24

    申请号：US11874352

    申请日：2007-10-18

    申请人： Yasuyoshi Takai ,  Hiroshi Shimoda ,  Shotaro Okabe ,  Koichi Matsuda ,  Hidetoshi Tsuzuki

    发明人： Yasuyoshi Takai ,  Hiroshi Shimoda ,  Shotaro Okabe ,  Koichi Matsuda ,  Hidetoshi Tsuzuki

    IPC分类号： H01L21/00

    CPC分类号： H01L21/67253 ,  C23C16/24 ,  C23C16/545 ,  H01L31/03685 ,  H01L31/03762 ,  H01L31/076 ,  H01L31/1824 ,  H01L31/202 ,  Y02E10/545 ,  Y02E10/548 ,  Y02P70/521

    摘要： A method for forming a deposited film containing microcrystalline silicon on a moving substrate by plasma-enhanced CVD includes forming a deposited film containing microcrystalline silicon on a moving substrate by plasma-enhanced CVD under conditions such that when a deposited film having a thickness of 300 nm or more is formed on a substrate while the substrate is in a stationary state, an area of the microcrystalline silicon region in which an intensity of Raman scattering attributed to a crystalline substance in the deposited film is equal to or higher than three times an intensity of Raman scattering attributed to an amorphous is 50% or more of the total area based on the area of the microcrystalline silicon region and the area of a region composed of the amorphous.

    摘要翻译： 通过等离子体增强CVD在移动基板上形成含有微晶硅的沉积膜的方法包括通过等离子体增强CVD在移动的衬底上形成含有微晶硅的沉积膜，使得当厚度为300nm的沉积膜 以上，在基板处于静止状态的同时，在基板上形成有由析出膜中的结晶物质引起的拉曼散射强度的微晶硅区域的面积等于或高于 归因于非晶体的拉曼散射基于微晶硅区域的面积和由无定形构成的区域的面积为总面积的50％以上。

    Non-volatile semiconductor memory device
    9.
    发明授权
    Non-volatile semiconductor memory device 有权
    非易失性半导体存储器件

    公开(公告)号：US06968435B2

    公开(公告)日：2005-11-22

    申请号：US10418046

    申请日：2003-04-18

    申请人： Hiroshi Shimoda

    发明人： Hiroshi Shimoda

    IPC分类号： G11C16/02 ,  G06F12/00 ,  G06F12/02 ,  G11C16/10

    CPC分类号： G11C16/102

    摘要： A non-volatile semiconductor memory device according to the invention includes a copy area latch circuit for latching information therein, a copy source address latch circuit for latching therein information read from a copy source, and write control means for comparing the information latched in the copy area latch circuit and the information latched in the copy source address latch circuit with each other, and automatically copying data latched in a source area of the copy source to a destination area of a copy destination, the destination area corresponding to the source area, until the information latched in the copy area latch circuit and the information latched in the copy source address latch circuit become coincide with each other following implementation of a newly provided copy command when data is copied from external storage means as a copy source to a non-volatile memory.

    摘要翻译： 根据本发明的非易失性半导体存储器件包括：用于锁存信息的复制区域锁存电路，用于锁存从复制源读取的信息的复制源地址锁存电路;以及用于将复制中锁存的信息进行比较的写入控制装置 区域锁存电路和锁存在复制源地址锁存电路中的信息，并且自动将锁存在复制源的源区域中的数据复制到复制目的地的目的地区域，对应于源区域的目的地区域，直到 锁存在复制区域锁存电路中的信息和在复制源地址锁存电路中锁存的信息在从作为复制源的外部存储装置复制到非易失性的情况下实现新提供的复制命令之后彼此重合 记忆。