摘要:
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect.A pharmaceutical composition having an analgesic effect or an improving effect of urination disorder comprising a compound of the formula (I): wherein Rh and Rj are taken together to form a bond; Ra and Rb and/or Rd and Re are taken together to form oxo or the like; Rc is hydrogen, substituted or unsubstituted alkyl or the like; Rf is —(CR4aR4b)n—R2; R4a and R4b are hydrogen, substituted or unsubstituted alkyl or the like; R2 is substituted or unsubstituted cycloalkyl or the like; n is an integer of 1 to 4; —Rg is —X—R3; —X— is —O—, —S— or the like; R3 is substituted or unsubstituted cycloalkyl or the like, or its pharmaceutically acceptable salt or a solvate thereof.
摘要:
The present invention provides a novel P2X3 and/or P2X2/3 receptor antagonist.A compound represented by the formula (I); wherein Ra, Rb and Rc are, (a) Ra and Rb are taken together ═Z; and Rc is a group represented by R1c; or (b) Rb and Rc are taken together to form a bond; and Ra is a group represented by —Y—R1a; R1a and R1c are each independently hydrogen, substituted or unsubstituted alkyl, etc.; R2 and R3 are each independently substituted or unsubstituted aryl, etc.; R4a and R4b are each independently hydrogen, substituted or unsubstituted alkyl, etc.; X is —N(R5)—, etc.; R5 is hydrogen, substituted or unsubstituted lower alkyl, etc.; —Y— is —O—, etc.; ═Z is ═O, etc.; and n is an integer of 0 to 4.
摘要:
The present invention provides a novel P2X3 and/or P2X2/3 receptor antagonist.A compound represented by the formula (I): wherein Ra, Rb and Rc are, (a) Ra and Rb are taken together ═Z; and Rc is a group represented by R1c; or (b) Rb and Rc are taken together to form a bond; and Ra is a group represented by —Y—R1a; R1a and R1c are each independently hydrogen, substituted or unsubstituted alkyl, etc.; R2 and R3 are each independently substituted or unsubstituted aryl, etc.; R4a and R4b are each independently hydrogen, substituted or unsubstituted alkyl, etc.; X is —N(R5)—, etc.; R5 is hydrogen, substituted or unsubstituted lower alkyl, etc.; —Y— is —O—, etc.; ═Z is ═O, etc.; and n is an integer of 0 to 4.
摘要:
To a video display device, a remote control transmitter for remotely operating the video display device is attached. When at least one of predetermined keys provided in the remote control transmitter of an external device is operated, the video display device switches, according to the setting of an “input target”, the validness and the invalidness of an remote operation on the at least one of predetermined keys of the external device which outputs a video stream to the video display device.
摘要:
Disclosed is a pilot multiplexing method in an Orthogonal Frequency Division Multiplexing (OFDM) system. Transmit data is transmitted by an OFDM signal through an OFDM scheme, pilot data is directly spread, and a spread-spectrum signal, which has been obtained by spreading, is transmitted in the same frequency band as that of the OFDM signal at the same time in superposition therewith or time-division multiplexed therewith. The spread-spectrum signal is a CDMA signal that has been obtained by spreading the pilot data by a prescribed spreading code.
摘要:
Provided is a light emitting device including: a light source; and a light guide plate that receives light emitted by the light source and emits it from a light emitting surface thereof. The light emitting device is provided with a fixing mechanism for fixing the light guide plate to a main body side of the light emitting device by using a structure that does not inhibit thermal expansion of the light guide plate.
摘要:
An image display apparatus includes a main body in which a display unit is disposed, and a backlight unit that is detachable from the main body and to which a plurality of LED modules are attached, each of which is provided with LEDs, so that the image display apparatus displays an image on the display unit with backlight light emitted by the LEDs. The plurality of LED modules are assigned with different channels as units of control of light emission luminance of the LEDs and can be replaced independently of each other.
摘要:
There is provided a millimeter wave imaging apparatus including: a lens antenna forming a subject image based on the millimeter waves from a subject; a line sensor including a plurality of millimeter wave sensors and capturing an image for one line of a predetermined width of the whole subject; a reflector having a reflecting surface reflecting millimeter waves; a reflection angle change device changing an angle of the reflecting surface; an image generation device generating an image of the whole subject from the respective subject images for one line; a millimeter wave radiation unit radiating a reference millimeter wave; a correction value setting device setting correction values with respect to the detected values by the millimeter wave sensors based on the millimeter wave from the millimeter wave radiation unit; and a detected value correction device correcting the detected values by the millimeter wave sensors with the correction values.
摘要:
A millimeter wave imaging apparatus includes: an imaging device including a plurality of millimeter wave sensors that are arranged in a planar manner and receive millimeter waves radiated from a subject to detect signal levels thereof; a temperature sensor that detects a temperature of the imaging device; a storage device that stores, with respect to the each of the millimeter wave sensors, temperature characteristics data indicating a relationship between the temperature detected by the temperature sensor and the output from the millimeter wave sensor; and an image data generation device that obtains a deviation of an output from the each of the millimeter wave sensors from reference temperature characteristics based on the temperature detected by the temperature sensor and the temperature characteristics data stored by the storage device, corrects the output from the each of the millimeter wave sensors based on the deviation, and thereby generates the image data.
摘要:
A brazing filler metal capable of improving both of oxidation resistance and corrosion resistance is obtained. This brazing filler metal (1, 1d, 51 and 51a) consists of at least a three-layer structure of an Ni—Cr brazing layer (2 and 2a) consisting of an Ni—Cr alloy layer, a Ti brazing layer (3, 3a, 3b, 3c and 3d) consisting of a Ti layer or a Ti alloy layer and an Ni brazing layer (4, 4a, 4b, 4c and 4d) consisting of an Ni layer or an N alloy layer arranged between the Ni—Cr brazing layer and the Ti brazing layer.