AGENTS FOR SUPPRESSING NEURAL FIBROTIC DEGENERATION
    1.
    发明申请
    AGENTS FOR SUPPRESSING NEURAL FIBROTIC DEGENERATION 审中-公开
    用于抑制神经纤维变性的药剂

    公开(公告)号:US20090202515A1

    公开(公告)日:2009-08-13

    申请号:US11576043

    申请日:2006-11-28

    IPC分类号: A61K38/47 C12N9/24 C12Q1/34

    摘要: The present invention examined the accumulation of chondroitin sulfate proteoglycans (CSPGs). The present invention relates to neurodegeneration-suppressing agents that are suitable for gene therapy or prevention of neural fibrotic degenerative diseases which induce neural cell death due to an accumulation of abnormal proteins, where the therapies are based on siRNAs against N-acetylgalactosamine-4-O-sulfotransferases (N-acetylgalactosamine-4-O-sulfotransferase-1, N-acetylgalactosamine-4-O-sulfotransferase-2, and N-acetylgalactosamine-4-sulfate 6-O-sulfotransferase (GalNAc4ST-1, GalNAc4ST-2, and GALNAC4S-6ST, respectively)), which are sulfotransferases for acetylgalactosamine, a CSPG side chain, and chondroitinase ABC, an enzyme that degrades chondroitin sulfate, another CSPG side chain.

    摘要翻译: 本发明检测了硫酸软骨素蛋白聚糖(CSPG)的积累。 本发明涉及适用于基因治疗或预防由于异常蛋白质积累引起神经细胞死亡的神经纤维变性疾病的神经变性抑制剂,其中所述疗法基于针对N-乙酰半乳糖胺-4- O的siRNA - 转氨酶(N-乙酰半乳糖胺-4- O - 磺基转移酶-1,N-乙酰半乳糖胺-4- -O-磺基转移酶-2和N-乙酰半乳糖胺-4-硫酸酯6-O-磺基转移酶(GalNAc4ST-1,GalNAc4ST-2和 分别为GALNAC4S-6ST)),其为乙酰半乳糖胺磺酸转移酶,CSPG侧链和软骨素酶ABC,其是降解硫酸软骨素,另一CSPG侧链的酶。

    Drowsiness detector
    3.
    发明授权
    Drowsiness detector 有权
    嗜睡检测器

    公开(公告)号:US08433095B2

    公开(公告)日:2013-04-30

    申请号:US12654976

    申请日:2010-01-12

    IPC分类号: G06K9/00

    摘要: A drowsiness detector detects the drowsiness by measuring a distance of an eyebrow at three points from a reference line defined by an inner eye corner and an outer eye corner. The three distances of the eyebrow from the reference line are respectively standardized by an inter-eye distance between the inner eye corners of the left and right eyes, and are respectively compared with thresholds for determining the rise of the eyebrow. The rise of the eyebrow is then translated as the start of the drowsiness, and is associated with an operation such as a doze prevention operation or the like.

    摘要翻译: 嗜睡检测器通过从由内眼角和外眼角限定的基准线测量三个点处测量眉毛的距离来检测困倦。 眉毛与参考线的三个距离分别通过左眼和右眼的内眼角之间的眼睛间距进行标准化,并分别与用于确定眉毛上升的阈值进行比较。 然后将眉毛的上升转换为睡意的开始,并且与诸如打盹预防操作等的操作相关联。

    Hand dryer
    4.
    外观设计
    Hand dryer 有权
    干手器

    公开(公告)号:USD664299S1

    公开(公告)日:2012-07-24

    申请号:US29409731

    申请日:2011-12-28

    申请人: Kenji Ishida

    设计人: Kenji Ishida

    System of processing music performance for personalized management and evaluation of sampled data
    5.
    发明授权
    System of processing music performance for personalized management and evaluation of sampled data 失效
    处理音乐表演的系统,用于个性化管理和评估采样数据

    公开(公告)号:US07297857B2

    公开(公告)日:2007-11-20

    申请号:US10640590

    申请日:2003-08-13

    IPC分类号: G10H1/00

    摘要: A performance processing apparatus is operable by user with aide of control and sound devices for providing sample music data to data management apparatus. A storage section stores original music data representing a music piece composed of tones. An acquisition section acquires input information from control device which has a detector for detecting either physical action or physiological state of user and operated by user to provide input information indicating detection result by detector. A processing section controls a performance parameter according to input information for enabling sound device to generate tones of the music piece represented by original music data and altered by user. A transmitting section transmits sample music data representing music piece composed of tones controlled by the performance parameter to the data management apparatus which has a storage device for storing sample music data for use as a material of evaluating mental or physical function of user.

    摘要翻译: 性能处理装置可由具有用于向数据管理装置提供样本音乐数据的控制和声音装置的用户操作。 存储部分存储表示由音调构成的乐曲的原始音乐数据。 获取部分从控制装置获取具有用于检测用户的物理动作或生理状态的检测器的控制装置的输入信息,并由用户操作以提供表示检测器的检测结果的输入信息。 处理部根据用于使声音装置产生由原始音乐数据表示并被用户改变的乐曲的音调的输入信息来控制演奏参数。 发送部将表示由演奏参数控制的音调构成的音乐的乐曲数据发送到数据管理装置,数据管理装置具有用于存储用作评估用户的心理或身体功能的材料的样本音乐数据的存储装置。

    Thin film and method for manufacturing same
    6.
    发明申请
    Thin film and method for manufacturing same 审中-公开
    薄膜及其制造方法

    公开(公告)号:US20060121203A1

    公开(公告)日:2006-06-08

    申请号:US10527712

    申请日:2003-09-11

    IPC分类号: B05D1/36

    摘要: A totally new method for manufacturing a thin film wherein only an arbitrary small region is structurally controlled. The structure of a film is controlled by applying a force to the entire film or an arbitrary region of the film using a part having a sharp tip during the film-forming process or after finishing the film formation. At this time, the temperature of the film is set at the glass transition point of the amorphous region or higher. An atomic force microscope can be used as an apparatus for realizing this manufacturing method.

    摘要翻译: 一种全新的制造薄膜的方法,其中只有结构上控制任意的小区域。 通过在成膜过程中或在成膜完成之后,使用具有尖锐尖端的部分在膜的整个膜或任意区域上施加力来控制膜的结构。 此时,将膜的温度设定在非晶区域的玻璃化转变点以上。 原子力显微镜可以用作实现该制造方法的装置。

    PROJECTION-TYPE IMAGE DISPLAY DEVICE AND LIGHT QUANTITY ADJUSTMENT METHOD
    10.
    发明申请
    PROJECTION-TYPE IMAGE DISPLAY DEVICE AND LIGHT QUANTITY ADJUSTMENT METHOD 审中-公开
    投影型图像显示装置和光量子调整方法

    公开(公告)号:US20130335643A1

    公开(公告)日:2013-12-19

    申请号:US14002097

    申请日:2011-03-04

    IPC分类号: H04N5/74

    摘要: A projection-type image display device includes: a light source; a display element that displays an image based on an input video signal; a trapezoidal distortion correction unit that performs pixel conversion in which pixel data of the input video signal are compressed or interpolated and supplies the display element with the corrected signal that includes a first video signal that is the video signal concerning which the pixel conversion has been carried out; a detection unit that detects the luminance distribution of the first video signal; and an adjustment unit that adjusts the light quantity of the light source based on the detected luminance distribution data.

    摘要翻译: 投影型图像显示装置包括:光源; 基于输入视频信号显示图像的显示元件; 梯形失真校正单元,执行其中输入视频信号的像素数据被压缩或内插的像素转换,并且向显示元件提供包括第一视频信号的校正信号,第一视频信号是与其相关的像素转换的视频信号 出来 检测单元,其检测第一视频信号的亮度分布; 以及调整单元,其基于检测到的亮度分布数据来调整光源的光量。