公开(公告)号：US20120021253A1

公开(公告)日：2012-01-26

申请号：US13260155

申请日：2010-03-03

申请人： Hiyoku Nakata ,  Akiko Hattori ,  Atsushi Tatsugawa ,  Ken Kawata

发明人： Hiyoku Nakata ,  Akiko Hattori ,  Atsushi Tatsugawa ,  Ken Kawata

IPC分类号： G11B5/33 ,  C07D257/02 ,  C07C43/23 ,  B32B9/00 ,  C10M105/18 ,  B05D1/18 ,  B05D3/12 ,  C23C16/44 ,  C10M105/70 ,  C07D251/54 ,  G11B5/65

CPC分类号： G11B5/725 ,  B05D1/18 ,  B05D3/12 ,  B32B9/00 ,  C07C43/225 ,  C07C43/23 ,  C07D225/00 ,  C07D251/54 ,  C07D251/70 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12 ,  C10M105/70 ,  C10M105/72 ,  C10M107/38 ,  C10M133/42 ,  C10M147/00 ,  C10M147/04 ,  C10M2211/04 ,  C10M2213/04 ,  C10M2213/06 ,  C10M2215/222 ,  C10M2215/2225 ,  C10M2223/083 ,  C10N2240/204 ,  C23C16/44 ,  G11B5/33 ,  G11B5/65 ,  Y10T428/11 ,  Y10T428/30

摘要： [Problem] Provided is a novel lubricant composition that is useful as a material of a lubricating layer of a magnetic recording medium.[Means for Resolution] The lubricant composition contains at least one kind of compound represented by the following Formula (1). In the formula, X represents a cyclic group that may be substituted, and Y represents a single bond or a linking group having a valency of 2 or more. Here, at least one of X and Y includes 1 or more polar groups such as a hydroxyl group; Z represents a linking group having a valency of 2 or more and constituted with a carbon atom (C), a fluorine atom (F), and 1 or 2 kinds of arbitrary atoms (here, a hydrogen atom is excluded); n represents a real number of 1 to 10; m represents a real number of 0 to 1; and s and t independently represent a real number of 1 or greater. XYZ—CnF2n+1-mHm]s]t  (1)

摘要翻译： [问题]提供了可用作磁记录介质的润滑层的材料的新型润滑剂组合物。 [解决方法]润滑剂组合物含有由下式（1）表示的至少一种化合物。 在该式中，X表示可被取代的环状基团，Y表示单键或2价以上的连接基。 这里，X和Y中的至少一个包括1个或更多个极性基团，例如羟基; Z表示由碳原子（C），氟原子（F）和1或2种任意原子构成的化合价为2以上的连接基（这里不排除氢原子）。 n表示1〜10的实数; m表示0到1的实数; s和t独立地表示1或更大的实数。 X（Y）Z-CnF2n + 1-mHm] s] t（1）

公开(公告)号：US09117475B2

公开(公告)日：2015-08-25

申请号：US13260155

申请日：2010-03-24

申请人： Hiyoku Nakata ,  Akiko Hattori ,  Atsushi Tatsugawa ,  Ken Kawata

发明人： Hiyoku Nakata ,  Akiko Hattori ,  Atsushi Tatsugawa ,  Ken Kawata

IPC分类号： C10M105/50 ,  G11B5/725 ,  C10M147/04 ,  C07C43/225 ,  C07C43/23 ,  C07D251/70 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12 ,  C10M105/70 ,  C10M105/72 ,  C10M133/42 ,  C23C16/44 ,  B32B9/00 ,  C10M147/00 ,  B05D3/12 ,  G11B5/65 ,  C10M107/38 ,  G11B5/33 ,  C07D251/54 ,  B05D1/18 ,  C07D225/00

CPC分类号： G11B5/725 ,  B05D1/18 ,  B05D3/12 ,  B32B9/00 ,  C07C43/225 ,  C07C43/23 ,  C07D225/00 ,  C07D251/54 ,  C07D251/70 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12 ,  C10M105/70 ,  C10M105/72 ,  C10M107/38 ,  C10M133/42 ,  C10M147/00 ,  C10M147/04 ,  C10M2211/04 ,  C10M2213/04 ,  C10M2213/06 ,  C10M2215/222 ,  C10M2215/2225 ,  C10M2223/083 ,  C10N2240/204 ,  C23C16/44 ,  G11B5/33 ,  G11B5/65 ,  Y10T428/11 ,  Y10T428/30

摘要： [Problem] Provided is a novel lubricant composition that is useful as a material of a lubricating layer of a magnetic recording medium.[Means for Resolution] The lubricant composition contains at least one kind of compound represented by the following Formula (1). In the formula, X represents a cyclic group that may be substituted, and Y represents a single bond or a linking group having a valency of 2 or more. Here, at least one of X and Y includes 1 or more polar groups such as a hydroxyl group; Z represents a linking group having a valency of 2 or more and constituted with a carbon atom (C), a fluorine atom (F), and 1 or 2 kinds of arbitrary atoms (here, a hydrogen atom is excluded); n represents a real number of 1 to 10; m represents a real number of 0 to 1; and s and t independently represent a real number of 1 or greater. XYZ—CnF2n+1−mHm]s]t  (1)

摘要翻译： [问题]提供了可用作磁记录介质的润滑层的材料的新型润滑剂组合物。 [解决方法]润滑剂组合物含有由下式（1）表示的至少一种化合物。 在该式中，X表示可被取代的环状基团，Y表示单键或2价以上的连接基。 这里，X和Y中的至少一个包括1个或更多个极性基团，例如羟基; Z表示由碳原子（C），氟原子（F）和1或2种任意原子构成的化合价为2以上的连接基（这里不排除氢原子）。 n表示1〜10的实数; m表示0到1的实数; s和t独立地表示1或更大的实数。 XYZ-CnF2n + 1-mHm] s] t（1）

公开(公告)号：US20110015422A1

公开(公告)日：2011-01-20

申请号：US12935151

申请日：2009-03-27

申请人： Saisuke Watanabe ,  Hiyoku Nakata ,  Ken Kawata

发明人： Saisuke Watanabe ,  Hiyoku Nakata ,  Ken Kawata

IPC分类号： C07C309/63 ,  C07C59/00

CPC分类号： C07F9/4071 ,  C07C69/34 ,  C07C69/36 ,  C07C69/38 ,  C07C69/40 ,  C07C69/42 ,  C07C69/44 ,  C07C69/60 ,  C07C69/63 ,  C07C69/708 ,  C07C69/734 ,  C07C69/76 ,  C07C69/80 ,  C07C69/82 ,  C07C217/08 ,  C07C271/12 ,  C07C271/66 ,  C07C307/02 ,  C07C309/65 ,  C07C309/70 ,  C07C311/53 ,  C07F7/0838 ,  C07F7/18 ,  C07F9/1411 ,  C10M129/78 ,  C10M2203/1006 ,  C10M2205/0285 ,  C10M2207/1265 ,  C10M2207/283 ,  C10M2207/2835 ,  C10M2207/30 ,  C10M2215/1026 ,  C10M2215/2203 ,  C10N2220/022 ,  C10N2230/06 ,  C10N2240/042 ,  C10N2240/10 ,  C10N2250/10 ,  C10N2250/16 ,  C10N2210/01

摘要： To provide a novel compound.It is disclosed a compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(═O)—) or a sulfonyl group (—S(═O)2—); D2 represents a carbonyl group (—C(═O)—), a sulfonyl group (—S(═O)2—), a carboxyl group (—C(═O)O—), a sulfonyloxyl group (—S(═O)2O—), a carbamoyl group (—C(═O)N(Alk)-) or a sulfamoyl group (—S(═O)2N(Alk)-); E represents a divaltn group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.

摘要翻译： 提供一种新型化合物。 公开了下述式（I）表示的化合物：A-L- {D1-（E）q-D2-（B）m-Z1-R} p。 在该式中，A表示p价链或环状残基; L表示单键或二价连接基团; p表示2以上的整数， D1表示羰基（-C（= O） - ）或磺酰基（-S（= O）2-））。 D2表示羰基（-C（= O） - ），磺酰基（-S（= O）2-），羧基（-C（= O）O-）），磺酰氧基（-S（ （O）2 O - ），氨基甲酰基（-C（= O）N（Alk） - ）或氨磺酰基（-S（= O）2 N（Alk） E代表一个群体; R代表氢原子，取代或未取代的C8或更长的烷基，全氟烷基或三烷基甲硅烷基。

公开(公告)号：US08552213B2

公开(公告)日：2013-10-08

申请号：US12935151

申请日：2009-03-27

申请人： Saisuke Watanabe ,  Hiyoku Nakata ,  Ken Kawata

发明人： Saisuke Watanabe ,  Hiyoku Nakata ,  Ken Kawata

IPC分类号： C07C69/34 ,  C07C69/36 ,  C07C69/40

CPC分类号： C07F9/4071 ,  C07C69/34 ,  C07C69/36 ,  C07C69/38 ,  C07C69/40 ,  C07C69/42 ,  C07C69/44 ,  C07C69/60 ,  C07C69/63 ,  C07C69/708 ,  C07C69/734 ,  C07C69/76 ,  C07C69/80 ,  C07C69/82 ,  C07C217/08 ,  C07C271/12 ,  C07C271/66 ,  C07C307/02 ,  C07C309/65 ,  C07C309/70 ,  C07C311/53 ,  C07F7/0838 ,  C07F7/18 ,  C07F9/1411 ,  C10M129/78 ,  C10M2203/1006 ,  C10M2205/0285 ,  C10M2207/1265 ,  C10M2207/283 ,  C10M2207/2835 ,  C10M2207/30 ,  C10M2215/1026 ,  C10M2215/2203 ,  C10N2220/022 ,  C10N2230/06 ,  C10N2240/042 ,  C10N2240/10 ,  C10N2250/10 ,  C10N2250/16 ,  C10N2210/01

摘要： To provide a novel compound.It is disclosed a compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(═O)—) or a sulfonyl group (—S(═O)2—); D2 represents a carbonyl group (—C(═O)—), a sulfonyl group (—S(═O)2—), a carboxyl group (—C(═O)O—), a sulfonyloxyl group (—S(═O)2O—), a carbamoyl group (—C(═O)N(Alk)-) or a sulfamoyl group (—S(═O)2N(Alk)-); E represents a divaltn group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.

摘要翻译： 提供一种新型化合物。 公开了下述式（I）表示的化合物：A-L- {D1-（E）q-D2-（B）m-Z1-R} p。 在该式中，A表示p价链或环状残基; L表示单键或二价连接基团; p表示2以上的整数， D1表示羰基（-C（= O） - ）或磺酰基（-S（= O）2-））。 R 2表示羰基（-C（= O） - ），磺酰基（-S（= O）2-），羧基（-C（= O）O-），磺酰氧基 =（O）2 O - ），氨基甲酰基（-C（= O）N（Alk） - ）或氨磺酰基（-S（= O）2N（Alk） E代表一个群体; R代表氢原子，取代或未取代的C8或更长的烷基，全氟烷基或三烷基甲硅烷基。

公开(公告)号：US08809371B2

公开(公告)日：2014-08-19

申请号：US13730000

申请日：2012-12-28

申请人： Hideyasu Fujiwara ,  Kimihiko Sato ,  Shinsuke Mizumoto ,  Yuichiro Sato ,  Hideki Kurihara ,  Yohei Kubo ,  Hiyoku Nakata ,  Yasutaka Baba ,  Takashi Tamura ,  Hidenobu Kuniyoshi ,  Shinji Hagiwara ,  Mari Yamamoto

发明人： Hideyasu Fujiwara ,  Kimihiko Sato ,  Shinsuke Mizumoto ,  Yuichiro Sato ,  Hideki Kurihara ,  Yohei Kubo ,  Hiyoku Nakata ,  Yasutaka Baba ,  Takashi Tamura ,  Hidenobu Kuniyoshi ,  Shinji Hagiwara ,  Mari Yamamoto

IPC分类号： C07D213/82

摘要： An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.

公开(公告)号：US08895585B2

公开(公告)日：2014-11-25

申请号：US13730000

申请日：2012-12-28

申请人： Hideyasu Fujiwara ,  Kimihiko Sato ,  Shinsuke Mizumoto ,  Yuichiro Sato ,  Hideki Kurihara ,  Yohei Kubo ,  Hiyoku Nakata ,  Yasutaka Baba ,  Takashi Tamura ,  Hidenobu Kuniyoshi ,  Shinji Hagiwara ,  Mari Yamamoto

发明人： Hideyasu Fujiwara ,  Kimihiko Sato ,  Shinsuke Mizumoto ,  Yuichiro Sato ,  Hideki Kurihara ,  Yohei Kubo ,  Hiyoku Nakata ,  Yasutaka Baba ,  Takashi Tamura ,  Hidenobu Kuniyoshi ,  Shinji Hagiwara ,  Mari Yamamoto

IPC分类号： C07D213/82

CPC分类号： C07D401/12 ,  C07D213/82 ,  C07D215/40 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/048 ,  C07D491/056 ,  C07D491/107 ,  C07D498/04 ,  C07D513/04

摘要： An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.

摘要翻译： 本发明的目的是提供具有优异的Syk抑制活性的化合物和药物组合物。 本发明提供下述式（I）表示的烟酰胺衍生物（其中，R1表示卤素原子，R2表示C1-12烷基，C2-12烯基，C2-12炔基，C3-8 环烷基，芳基，芳基-C 1-6烷基或杂环基，各自任选具有至少一个取代基; R 3表示各自任选具有至少一个取代基的芳基或杂环基;以及R 4和R 5各自 独立地表示氢原子; R2和R4可以形成任选具有至少一个取代基的环状氨基以及与它们结合的氮原子）或其盐，以及用于治疗Syk- 其包含烟酰胺衍生物或其盐。

公开(公告)号：US08772320B2

公开(公告)日：2014-07-08

申请号：US13730000

申请日：2012-12-28

申请人： Hideyasu Fujiwara ,  Kimihiko Sato ,  Shinsuke Mizumoto ,  Yuichiro Sato ,  Hideki Kurihara ,  Yohei Kubo ,  Hiyoku Nakata ,  Yasutaka Baba ,  Takashi Tamura ,  Hidenobu Kuniyoshi ,  Shinji Hagiwara ,  Mari Yamamoto

发明人： Hideyasu Fujiwara ,  Kimihiko Sato ,  Shinsuke Mizumoto ,  Yuichiro Sato ,  Hideki Kurihara ,  Yohei Kubo ,  Hiyoku Nakata ,  Yasutaka Baba ,  Takashi Tamura ,  Hidenobu Kuniyoshi ,  Shinji Hagiwara ,  Mari Yamamoto

IPC分类号： C07D213/82

摘要： An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.

公开(公告)号：US20100196724A1

公开(公告)日：2010-08-05

申请号：US12680168

申请日：2008-09-25

申请人： Sumiaki Yamasaki ,  Satoshi Tanaka ,  Hiyoku Nakata ,  Yuichiro Murayama ,  Yoshiaki Kondo

发明人： Sumiaki Yamasaki ,  Satoshi Tanaka ,  Hiyoku Nakata ,  Yuichiro Murayama ,  Yoshiaki Kondo

IPC分类号： B32B15/08 ,  C08L83/00 ,  B32B15/20

CPC分类号： C09D143/04 ,  C09D5/165 ,  C09D5/1687 ,  Y10T428/31663

摘要： A hydrophilic film forming composition which is used for forming on the surface of a support of every sort a hydrophilic film provided with anti-fogging properties, abrasion resistance and antibacterial properties and having more favorable antifouling properties is provided. A hydrophilic member having an excellent anti-fogging, abrasion-resistant, antibacterial and antifouling surface provided with a hydrophilic film formed of the instant hydrophilic film forming composition on the surface of an appropriate support is provided.A hydrophilic film forming composition including (A) a positively charged nitrogen atom-containing compound having a Log P of not more than 2; (B) a hydrolyzable silyl group-containing hydrophilic polymer; and (C) a metal complex catalyst. A hydrophilic member including a support having the instant hydrophilic film forming composition coated thereon.

摘要翻译： 提供了一种亲水性成膜组合物，其用于在各种支撑体的表面上形成具有防雾性，耐磨性和抗菌性并具有更好的防污性的亲水性膜。 提供了具有优异的防雾，耐磨，抗菌和防污表面的亲水构件，其在适当的载体的表面上设置由立即亲水性成膜组合物形成的亲水膜。 一种亲水性成膜组合物，其包含（A）具有不大于2的Log P的带正电的含氮原子的化合物; （B）含水解性甲硅烷基的亲水性聚合物; 和（C）金属络合物催化剂。 亲水性构件，其包括其上涂覆有即时亲水性成膜组合物的载体。