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    Apparatus for microfluid detection
    1.
    发明授权
    Apparatus for microfluid detection 有权
    微流体检测装置

    公开(公告)号：US09341639B2

    公开(公告)日：2016-05-17

    申请号：US14221286

    申请日：2014-03-21

    Applicant: Industrial Technology Research Institute

    Inventor： Liang-Ju Chien ,  Chi-Han Chiou ,  Shao-Hsing Yeh ,  Yu-Ying Lin

    IPC: G01N35/00 ,  B01L3/00

    CPC classification number: G01N35/0098 ,  B01L3/502792 ,  B01L2200/0668 ,  B01L2300/087 ,  B01L2300/1861 ,  B01L2400/043

    Abstract: A apparatus for microfluid detection for detecting a sample fluid including a plurality of magnetic particles is provided. The apparatus for microfluid detection includes a microfluidic chip and a magnetic generating module. The microfluidic chip includes a substrate and microfluidic channels, wherein the sample fluid is carried by a carry surface of the substrate. The magnetic generating module is adapted for providing a positioning magnetic field and a surrounding magnetic field. The magnetic module controls to move the sample fluid and change a distribution of the magnetic particles in the sample fluid through the positioning magnetic field and the surrounding magnetic field.

    Abstract translation: 提供了一种用于检测包括多个磁性颗粒的样品流体的微流体检测装置。 用于微流体检测的装置包括微流体芯片和磁发生模块。 微流体芯片包括基底和微流体通道，其中样品流体由基底的携带表面承载。 磁性发生模块适于提供定位磁场和周围磁场。 磁性模块控制移动样品流体并通过定位磁场和周围磁场改变样品流体中磁性颗粒的分布。

    APPARATUS FOR MICROFLUID DETECTION
    2.
    发明申请
    APPARATUS FOR MICROFLUID DETECTION 有权
    微流感检测装置

    公开(公告)号：US20150029491A1

    公开(公告)日：2015-01-29

    申请号：US14221286

    申请日：2014-03-21

    Applicant: Industrial Technology Research Institute

    Inventor： Liang-Ju Chien ,  Chi-Han Chiou ,  Shao-Hsing Yeh ,  Yu-Ying Lin

    IPC: G01N1/28

    CPC classification number: G01N35/0098 ,  B01L3/502792 ,  B01L2200/0668 ,  B01L2300/087 ,  B01L2300/1861 ,  B01L2400/043

    Abstract: A apparatus for microfluid detection for detecting a sample fluid including a plurality of magnetic particles is provided. The apparatus for microfluid detection includes a microfluidic chip and a magnetic generating module. The microfluidic chip includes a substrate and microfluidic channels, wherein the sample fluid is carried by a carry surface of the substrate. The magnetic generating module is adapted for providing a positioning magnetic field and a surrounding magnetic field. The magnetic module controls to move the sample fluid and change a distribution of the magnetic particles in the sample fluid through the positioning magnetic field and the surrounding magnetic field.

    Abstract translation: 提供了一种用于检测包括多个磁性颗粒的样品流体的微流体检测装置。 用于微流体检测的装置包括微流体芯片和磁发生模块。 微流体芯片包括基底和微流体通道，其中样品流体由基底的携带表面承载。 磁性发生模块适于提供定位磁场和周围磁场。 磁性模块控制移动样品流体并通过定位磁场和周围磁场改变样品流体中磁性颗粒的分布。

    DIELECTROPHORETIC PARTICLE CONCENTRATOR AND CONCENTRATION WITH DETECTION METHOD
    5.
    发明申请
    DIELECTROPHORETIC PARTICLE CONCENTRATOR AND CONCENTRATION WITH DETECTION METHOD 审中-公开
    电磁颗粒浓缩器和浓度检测方法

    公开(公告)号：US20140291154A1

    公开(公告)日：2014-10-02

    申请号：US14302443

    申请日：2014-06-12

    Applicant: Industrial Technology Research Institute

    Inventor： Liang-Ju Chien ,  Chi-Han Chiou

    IPC: B03C5/00

    CPC classification number: B03C5/005 ,  B03C5/026 ,  B03C2201/26

    Abstract: A concentration method of dielectrophoretic particles includes: providing a fluid pipe structure, wherein the fluid pipe structure has a protrudent structure lateral protruding inwardly so as to form a line-like gate; making a fluid containing particles to be measured flow through the fluid pipe structure; and applying an electrical field through the line-like gate so as to produce a dielectrophoresis force to concentrate the particles to be measured.

    Abstract translation: 介电电泳颗粒的浓缩方法包括：提供流体管结构，其中流体管结构具有向内突出的突出结构，以形成线状栅极; 使含有待测量颗粒的流体流过流体管道结构; 并且通过线状栅极施加电场，以产生介电电泳力以浓缩待测量的颗粒。

    Method for manipulating droplet
    7.
    发明授权
    Method for manipulating droplet 有权
    操纵液滴的方法

    公开(公告)号：US09279820B2

    公开(公告)日：2016-03-08

    申请号：US14706353

    申请日：2015-05-07

    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

    Inventor： Shao-Hsing Yeh ,  Yu-Ying Lin ,  Chi-Han Chiou ,  Liang-Ju Chien

    IPC: G01N15/06 ,  G01N33/00 ,  G01N33/48 ,  G01N35/00 ,  G01N1/28

    CPC classification number: G01N35/0098 ,  B01L3/502761 ,  B01L3/502784 ,  B01L2200/0647 ,  B01L2300/087 ,  B01L2400/043 ,  B03C1/01 ,  B03C1/0335 ,  B03C1/035 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N1/28 ,  Y10T137/0391 ,  Y10T137/206 ,  Y10T137/2191 ,  Y10T137/2224

    Abstract: A method for manipulating a droplet by a droplet manipulating device including a flow channel, a first magnetic field generator, and a second magnetic field generator is provided. The first magnetic field generator includes two first magnetic field modules and are at two sides of the flow channel. The second magnetic field generator is between the two first magnetic field modules and includes multiple second magnetic field coils. The droplet is provided in the flow channel and includes a magnetic particle. A first magnetic field is produced on the flow channel by the first magnetic field modules, so the magnetic particle in the droplet has the direction of magnetic field corresponding to the first magnetic field. A second magnetic field is produced on the flow channel by the second magnetic field coils, for driving the magnetic particle in the droplet to be in motion in the flow channel.

    Abstract translation: 提供了一种通过包括流动通道的液滴操纵装置来操纵液滴的方法，第一磁场发生器和第二磁场发生器。 第一磁场发生器包括两个第一磁场模块，并且位于流动通道的两侧。 第二磁场发生器位于两个第一磁场模块之间，并且包括多个第二磁场线圈。 液滴设置在流路中并包括磁性颗粒。 通过第一磁场模块在流动通道上产生第一磁场，因此液滴中的磁性颗粒具有对应于第一磁场的磁场方向。 通过第二磁场线圈在流路上产生第二磁场，用于驱动液滴中的磁性颗粒在流动通道中运动。

    DETECTION CHIP AND METHOD FOR USING THE SAME
    8.
    发明申请
    DETECTION CHIP AND METHOD FOR USING THE SAME 有权
    检测芯片及其使用方法

    公开(公告)号：US20150011438A1

    公开(公告)日：2015-01-08

    申请号：US14221289

    申请日：2014-03-21

    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

    Inventor： Liang-Ju Chien ,  Yu-Ying Lin ,  Chi-Han Chiou

    IPC: B01L3/00

    CPC classification number: B01L3/502792 ,  B01F13/0071 ,  B01L3/50273 ,  B01L2200/0647 ,  B01L2200/0673 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/161 ,  B01L2400/0421 ,  B01L2400/0427 ,  B01L2400/043 ,  C12Q1/686 ,  Y10T436/2575 ,  C12Q2565/629

    Abstract: A detection chip is provided. The detection chip includes a substrate, an active reagent, a hydrophilic droplet and a lipophilic substance. The substrate includes a first containing slot, wherein the first containing slot includes a first space and a second space adjacent to each other. The active reagent is disposed in the first space of the first containing slot. The hydrophilic droplet is disposed in the second space of the first containing slot. The lipophilic substance is disposed in the first containing slot, wherein the lipophilic substance is immiscible to the active reagent and the hydrophilic droplet, and separates the active reagent from the hydrophilic droplet.

    Abstract translation: 提供检测芯片。 检测芯片包括基板，活性试剂，亲水性液滴和亲脂性物质。 衬底包括第一容纳槽，其中第一容纳槽包括彼此相邻的第一空间和第二空间。 活性试剂设置在第一容纳槽的第一空间中。 亲水性液滴设置在第一容纳槽的第二空间中。 亲脂性物质设置在第一容纳槽中，其中亲脂性物质与活性试剂和亲水性液滴不混溶，并将活性试剂与亲水性液滴分离。

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