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    HYDROGEL
    1.
    发明申请
    HYDROGEL 有权

    公开(公告)号：US20220185927A1

    公开(公告)日：2022-06-16

    申请号：US17600072

    申请日：2020-12-01

    申请人： ILLUMINA CAMBRIDGE LIMITED

    发明人： Gianluca Andrea Artioli ,  Andrew A. Brown ,  Wayne N. George ,  Colin Pilkington ,  Jem Pitcairn ,  Alexandre Richez ,  Xavier von Hatten

    IPC分类号： C08F220/60 ,  C08F2/38

    摘要： A hydrogel includes a dendritic core with 2 to 30 arms, and first and second acrylamide monomers incorporated into each arm. The first acrylamide monomer is: (I), wherein R1 and R2 are independently selected from an alkyl, an alkylamino, an alkylamido, an alkylthio, an aryl, a glycol, and optionally substituted variants thereof; and the second acrylamide monomer is: (II), wherein R3 and R4 are independently hydrogen or an alkyl; L is a linker including a linear chain of 2 to 20 atoms selected from carbon, oxygen, and nitrogen and optional substituents on the carbon and any nitrogen atoms; A is an N substituted amide: (III), where R5 is hydrogen or an alkyl; E is a linear chain of 1 to 4 atom(s) selected from carbon, oxygen and nitrogen, and optional substituents on the carbon and any nitrogen atoms; and Z is an optional nitrogen containing heterocycle.