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公开(公告)号：US07517387B2
公开(公告)日：2009-04-14
申请号：US10518787
申请日：2003-05-26
IPC分类号： B01D19/00
CPC分类号： B01D19/0057 , A61M1/3437 , A61M1/3627 , A61M1/3639 , A61M1/3641 , A61M1/3676 , A61M2205/3382 , A61M2206/16 , B01F5/0057 , B04C5/103
摘要： A description is given of a gas separation device for a physiological fluid, comprising a containing body (6) having at least a first inlet aperture (7) for a physiological fluid, positioned with a tangential direction of access, at least one outlet aperture (9) for the said fluid, spaced apart from the said inlet aperture, and a guide element (17) housed within the said body. The guide element (17) has a continuous active surface (15) designed to contact and guide the said fluid and delimits, together with the containing body (6), a first annular chamber (20) into which the first inlet aperture (7) opens directly.
摘要翻译： 给出了用于生理流体的气体分离装置的描述，其包括容纳体，其具有至少一个生理流体的第一入口孔，定位在切向方向上，至少一个用于所述流体的出口孔间隔开 和所述入口孔中的引导元件，以及容纳在所述主体内的引导元件。 引导元件具有设计成接触和引导所述流体并且与容纳体一起限定第一入口孔直接打开的第一环形室的连续活性表面。
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公开(公告)号：US20050247203A1
公开(公告)日：2005-11-10
申请号：US10518787
申请日：2003-05-26
CPC分类号： B01D19/0057 , A61M1/3437 , A61M1/3627 , A61M1/3639 , A61M1/3641 , A61M1/3676 , A61M2205/3382 , A61M2206/16 , B01F5/0057 , B04C5/103
摘要： A description is given of a gas separation device for a physiological fluid, comprising a containing body (6) having at least a first inlet aperture (7) for a physiological fluid, positioned with a tangential direction of access, at least one outlet aperture (9) for the said fluid, spaced apart from the said inlet aperture, and a guide element (17) housed within the said body. The guide element (17) has a continuous active surface (15) designed to contact and guide the said fluid and delimits, together with the containing body (6), a first annular chamber (20) into which the first inlet aperture (7) opens directly.
摘要翻译： 给出了用于生理流体的气体分离装置的描述，其包括容纳体（6），该容纳体具有至少一个用于生理流体的第一入口孔（7），定位在切向方向上，至少一个出口孔 所述流体与所述入口孔间隔开，以及容纳在所述主体内的引导元件（17）。 引导元件（17）具有设计成接触和引导所述流体并与容纳体（6）一起界定的连续有效表面（15），第一环形室（20），第一入口孔（7） 直接打开
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3.发明申请Device and process for controlling blood circulation for a single needle circuit 失效用于控制单针电路血液循环的装置和过程公开(公告)号：US20050205476A1
公开(公告)日：2005-09-22
申请号：US11074067
申请日：2005-03-08
IPC分类号： A61M1/10 , A61M1/30 , B01D35/143
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1039 , A61M1/1081 , A61M1/302 , A61M1/303 , A61M1/308
摘要： Device for extracorporeal treatment of blood 1 intended to operate in a mode with a single needle 2, comprising: a treatment unit 3 having a first compartment 4 and a second compartment 5, which are separated by a semipermeable membrane 6, an extracorporeal blood circuit comprising a single needle 2, an intake line 7 in fluid communication with the first compartment 4 of the treatment unit 3, the first compartment 4, and a return line 8 in fluid communication with the first compartment 4 of the treatment unit 3, a purge line 9 at the outlet of the second compartment 5, a closure means (10, 11) acting on at least the intake line 7 and the return line 8 in order to generate the alternate sequence of blood intake and return, at least a first chamber 12 which is in fluid communication with the extracorporeal blood circuit and defines a first additional blood volume, the first chamber 12 having a variable total content; the first chamber 4 being rigid and including at least one wall capable of being moved, the device including a means 19 acting on the chamber 12 in order to modify the volume of the chamber 12, making it possible to store blood during the arterial phase and release blood during the venous phase.
摘要翻译： 用于体外处理用于以单针2模式操作的血液1的装置，包括：具有由半透膜6分离的第一隔室4和第二隔室5的治疗单元3，体外血液回路包括 单个针2，与处理单元3的第一隔室4流体连通的进入管线7，第一隔室4和与处理单元3的第一隔室4流体连通的返回管线8，净化管线 9，在第二隔室5的出口处，至少作用在进气管线7和返回管线8上的闭合装置（10,11），以产生血液进入和返回的交替序列，至少第一室12 其与体外血液回路流体连通并限定第一附加血液体积，第一腔室12具有可变的总含量; 第一腔室4是刚性的并且包括能够被移动的至少一个壁，该装置包括作用在腔室12上的装置19，以便改变腔室12的体积，使得可以在动脉期期间储存血液， 在静脉期释放血液。
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公开(公告)号：US07540958B2
公开(公告)日：2009-06-02
申请号：US11074067
申请日：2005-03-08
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1039 , A61M1/1081 , A61M1/302 , A61M1/303 , A61M1/308
摘要： Device for extracorporeal treatment of blood 1 intended to operate in a mode with a single needle 2, comprising: a treatment unit 3 having a first compartment 4 and a second compartment 5, which are separated by a semipermeable membrane 6, an extracorporeal blood circuit comprising a single needle 2, an intake line 7 in fluid communication with the first compartment 4 of the treatment unit 3, the first compartment 4, and a return line 8 in fluid communication with the first compartment 4 of the treatment unit 3, a purge line 9 at the outlet of the second compartment 5, a closure means (10, 11) acting on at least the intake line 7 and the return line 8 in order to generate the alternate sequence of blood intake and return, at least a first chamber 12 which is in fluid communication with the extracorporeal blood circuit and defines a first additional blood volume, the first chamber 12 having a variable total content; the first chamber 4 being rigid and including at least one wall capable of being moved, the device including a means 19 acting on the chamber 12 in order to modify the volume of the chamber 12, making it possible to store blood during the arterial phase and release blood during the venous phase.
摘要翻译： 用于体外处理用于以单针2模式操作的血液1的装置，包括：具有由半透膜6分离的第一隔室4和第二隔室5的治疗单元3，体外血液回路包括 单个针2，与处理单元3的第一隔室4流体连通的进入管线7，第一隔室4和与处理单元3的第一隔室4流体连通的返回管线8，净化管线 9，在第二隔室5的出口处，至少作用在进气管线7和返回管线8上的闭合装置（10,11），以产生血液进入和返回的交替序列，至少第一室12 其与体外血液回路流体连通并限定第一附加血液体积，第一腔室12具有可变的总含量; 第一腔室4是刚性的并且包括能够被移动的至少一个壁，该装置包括作用在腔室12上的装置19，以便改变腔室12的体积，使得可以在动脉期期间储存血液， 在静脉期释放血液。
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5.发明授权Process and device for sterilizing and dispensing a liquid for medical use 失效用于消毒和分配用于医疗用途的液体的方法和装置公开(公告)号：US06579494B1
公开(公告)日：2003-06-17
申请号：US09537307
申请日：2000-03-29
申请人： Jacques Chevallet , Thierry Court , Michael John Dunkley , Alain Frugier , Lennart Jonsson , Nicholas John Kerry , Hiram Rada , Jean-Louis Romarie
发明人： Jacques Chevallet , Thierry Court , Michael John Dunkley , Alain Frugier , Lennart Jonsson , Nicholas John Kerry , Hiram Rada , Jean-Louis Romarie
IPC分类号： G05B2300
CPC分类号： A61L2/28 , A61L2/0023 , A61L2/04
摘要： A device for preparing a sterile liquid includes structure for validating a sterilization treatment applied to the liquid. The validating structure includes structure for calculating, from at least one operating parameter of the device, a parameter representing a sterilizing value for the sterilization treatment, and structure for comparing the calculated parameter to a threshold value corresponding to the sterility of the liquid.
摘要翻译： 用于制备无菌液体的装置包括用于验证施加到液体的灭菌处理的结构。 验证结构包括从装置的至少一个操作参数计算表示灭菌处理的消毒值的参数的结构，以及用于将所计算的参数与对应于液体的无菌性的阈值进行比较的结构。
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6.发明授权Device for measuring the pressure of a liquid and method for regulating such a device 失效用于测量液体压力的装置和用于调节这种装置的方法
公开(公告)号：US5722399A
公开(公告)日：1998-03-03
申请号：US465047
申请日：1995-06-06
申请人： Jacques Chevallet , Alain Frugier , Eric Louvet
发明人： Jacques Chevallet , Alain Frugier , Eric Louvet
CPC分类号： G01L11/006 , A61M1/3639 , A61M1/16 , A61M2205/3344 , A61M2205/3351 , A61M2205/3355
摘要： A liquid treatment apparatus includes a sensor which is sensitive to a variation in gas pressure and which generates signals indicative of sensed pressures. The apparatus also included a casing divided into a first compartment and a second compartment by a flexible membrane, the first compartment having at least one orifice for the introduction of the liquid, and the second compartment being connectable in a leaktight manner to the pressure sensor. A pump is provided to vary a quantity of gas in the second compartment, and a controller is provided to regulate the pump as a function of variations in pressure generated in the second compartment. The controller is configured to receive signals from the sensor and to cause, through the pump, at least two successive pressure variations, having opposite directions, in the second compartment so as to adjust said position of the membrane between a wall of the casing bounding the first compartment and a wall of the casing bounding the second compartment.
摘要翻译： 液体处理装置包括对气体压力变化敏感的并且产生指示感测压力的信号的传感器。 该装置还包括通过柔性膜分成第一隔室和第二隔室的壳体，第一隔室具有用于引入液体的至少一个孔，并且第二隔室以密封方式连接到压力传感器。 提供泵以改变第二隔室中的气体量，并且提供控制器以根据在第二隔室中产生的压力变化来调节泵。 控制器被配置为从传感器接收信号并且通过泵在第二隔室中引起具有相反方向的至少两个连续的压力变化，以便调节膜的位于封套的壳体的壁之间的位置 第一隔室和围绕第二隔室的壳体的壁。
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公开(公告)号：US20100168643A1
公开(公告)日：2010-07-01
申请号：US12674110
申请日：2007-10-31
IPC分类号： A61M1/36
CPC分类号： A61M1/3653 , A61M1/024 , A61M1/34 , A61M1/3413 , A61M1/342 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3458 , A61M1/3627 , A61M1/3659 , A61M1/3672 , A61M1/3675 , A61M25/0074 , A61M2025/0031 , A61M2202/0021 , A61M2202/0042 , A61M2206/16
摘要： The invention relates to a blood line (108) comprising an infusion site (145) intended to inject into the line a solution, comprising: —a first main channel (200) having a first passage section, —a second main channel (220) having a second passage section, —means for the formation (210) of a turbulence area located downstream from the first main channel, located upstream from the second main channel, these formation means comprising a first fluid passage means (224) defining a reduction (225) in the passage section and whose smallest passage section is smaller than the first passage section and smaller than the second fluid passage section, —a secondary channel (230) comprising an inlet (231) for letting in the solution and an outlet (232) in fluid communication with the first main channel or the means for the formation of a turbulence area or the second main channel.
摘要翻译： 本发明涉及一种血液管线（108），其包括用于向管线注射溶液的输注部位（145），包括： - 具有第一通道部分的第一主通道（200）， - 第二主通道（220） 具有第二通道部分， - 用于形成位于第一主通道下游的湍流区域（210），位于第二主通道的上游，这些形成装置包括限定还原的第一流体通道装置（224） 225），其最小通道部分小于第一通道部分并且小于第二流体通道部分， - 第二通道（230），其包括用于将溶液中的入口（231）和出口（232） ）与第一主通道或用于形成湍流区域或第二主通道的装置流体连通。
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8.发明申请MEDICAL APPARATUS FOR EXTRACORPOREAL TREATMENT OF FLUID AND A PROCESS OF CALCULATING SET FLOW RATES IN A MEDICAL APPARATUS FOR DELIVERY OR COLLECTION OF FLUIDS 审中-公开用于流体处理的医疗装置和计算用于输送或收集流体的医疗装置中的流量的方法公开(公告)号：US20150034536A1
公开(公告)日：2015-02-05
申请号：US14342028
申请日：2012-08-22
CPC分类号： A61M1/1613 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1611 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3609 , A61M2202/0413 , A61M2205/3331 , A61M2205/3334 , A61M2205/502 , A61M2205/52 , A61M2205/75 , G01F1/00
摘要： An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit (10) is configured calculate set values of two or more of the fluid flow rates by imposing that an emptying time of containers of fresh fluid (16, 20, 21, 26) and/or a filling time of a waste container is substantially same as, or multiple of the emptying time of one or more of the other containers of fresh fluid.
摘要翻译： 公开了用于流体的体外治疗的装置和设置用于输送或收集流体的医疗装置的过程。 根据该装置和过程，控制单元（10）被配置为通过将新鲜流体（16,20,21,26）的容器的排空时间和/ 或废物容器的填充时间与新鲜流体的一个或多个其他容器的排空时间基本相同或多个。
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公开(公告)号：US06349170B1
公开(公告)日：2002-02-19
申请号：US09481454
申请日：2000-01-11
IPC分类号： A61F700
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/3627 , A61M1/3639 , A61M1/369 , A61M2209/082
摘要： An integrated CRRT method and apparatus incorporates steps and means for compensating for heat loss from blood in an extracorporeal circuit. A blood warmer is designed to engage and hold a disposable blood tube segment to transfer heat at a closely controlled temperature to blood flowing in the disposable blood tube segment. Another significant aspect of the present invention is a blood tube segment for engagement with the blood warmer is located in downstream of a dialyzer and upstream of a venous pressure monitor, an air bubble detector and a venous line clamp. The disposable blood tube segment may be selectively connected when heat loss compensation is required and left disconnected when heat loss compensation is not required.
摘要翻译： 集成的CRRT方法和装置包括用于补偿来自体外循环中血液的热损失的步骤和装置。 血液加热器被设计成接合和保持一次性血管部分，以在紧密控制的温度下将热量传递到在一次性血管部分中流动的血液。 本发明的另一个重要方面是用于与血液加热器接合的血管部分位于透析器的下游，并且位于静脉压监视器，气泡检测器和静脉管线夹具的上游。 当需要热损失补偿时，可以选择性地连接一次性血管部分，并且当不需要热损失补偿时将其断开。
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公开(公告)号：US08715217B2
公开(公告)日：2014-05-06
申请号：US12674110
申请日：2007-10-31
CPC分类号： A61M1/3653 , A61M1/024 , A61M1/34 , A61M1/3413 , A61M1/342 , A61M1/3431 , A61M1/3434 , A61M1/3437 , A61M1/3458 , A61M1/3627 , A61M1/3659 , A61M1/3672 , A61M1/3675 , A61M25/0074 , A61M2025/0031 , A61M2202/0021 , A61M2202/0042 , A61M2206/16
摘要： The invention relates to a blood line (108) comprising an infusion site (145) intended to inject into the line a solution, comprising: —a first main channel (200) having a first passage section, —a second main channel (220) having a second passage section, —means for the formation (210) of a turbulence area located downstream from the first main channel, located upstream from the second main channel, these formation means comprising a first fluid passage means (224) defining a reduction (225) in the passage section and whose smallest passage section is smaller than the first passage section and smaller than the second fluid passage section, —a secondary channel (230) comprising an inlet (231) for letting in the solution and an outlet (232) in fluid communication with the first main channel or the means for the formation of a turbulence area or the second main channel.
摘要翻译： 本发明涉及一种血液管线（108），其包括用于向管线注入溶液的输注部位（145），包括： - 具有第一通道部分的第一主通道（200）， - 第二主通道（220） 具有第二通道部分， - 用于形成位于第一主通道下游的湍流区域（210），位于第二主通道的上游，这些形成装置包括限定还原的第一流体通道装置（224） 225），其最小通道部分小于第一通道部分并且小于第二流体通道部分， - 第二通道（230），其包括用于将溶液中的入口（231）和出口（232） ）与第一主通道或用于形成湍流区域或第二主通道的装置流体连通。
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