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    Pirazino(AZA) indole derivatives
    2.
    发明申请
    Pirazino(AZA) indole derivatives 审中-公开
    吡嗪嗪（AZA）吲哚衍生物

    公开(公告)号：US20060160816A1

    公开(公告)日：2006-07-20

    申请号：US11374157

    申请日：2006-03-14

    Applicant: David Adams ,  Jon Bentley ,  James Davidson ,  Matthew Dunction ,  Richard Porter

    Inventor： David Adams ,  Jon Bentley ,  James Davidson ,  Matthew Dunction ,  Richard Porter

    IPC: A61K31/498 ,  C07D487/04

    CPC classification number: C07D487/04

    Abstract: Chemical compounds of formula (I): and pharmaceutically acceptable salts and addition compounds and prodrugs thereof are useful in therapy, particularly for the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes inspidus, and sleep apnea.

    Abstract translation: 式（I）的化合物及其药学上可接受的盐和加成化合物及其前药可用于治疗，特别是用于治疗中枢神经系统疾病; 损害中枢神经系统; 心血管疾病; 胃肠道疾病; 糖尿病，睡眠呼吸暂停。

    Method of assembly of bathtub enclosure
    4.
    发明申请
    Method of assembly of bathtub enclosure 审中-公开
    浴缸罩组装方法

    公开(公告)号：US20100132181A1

    公开(公告)日：2010-06-03

    申请号：US12457340

    申请日：2009-06-08

    Applicant: Trevor Sullivan ,  James Davidson ,  Michael Burrall ,  David Solomon

    Inventor： Trevor Sullivan ,  James Davidson ,  Michael Burrall ,  David Solomon

    IPC: B23P17/04

    CPC classification number: A47K3/16 ,  Y10T29/49826

    Abstract: An enclosure for a bathtub is constructed at a factory or other location remote from a site where the bathtub is to be permanently installed. The bathtub is placed permanently in the enclosure at the factory or remote location and once placed, the bathtub and enclosure are in condition for use at its permanent site without the necessity of further assembly.

    Abstract translation: 一个浴缸的外壳是在一个工厂或远离一个要永久安装浴缸的地方的其他位置建造的。 浴缸永久放置在工厂或远程位置的外壳中，一旦放置，浴缸和外壳将处于其永久位置使用的状态，无需进一步组装。

    Mri/nmr compatible hyperpolarized gas delivery valves for ventilators and associated gas delivery methods
    5.
    发明申请
    Mri/nmr compatible hyperpolarized gas delivery valves for ventilators and associated gas delivery methods 审中-公开
    Mri / nmr兼​​容超极化气体输送阀，用于呼吸机和相关气体输送方法

    公开(公告)号：US20070144523A1

    公开(公告)日：2007-06-28

    申请号：US10547436

    申请日：2004-02-25

    Applicant: Kenneth Bolam ,  James Davidson ,  James Borgen

    Inventor： Kenneth Bolam ,  James Davidson ,  James Borgen

    IPC: A62B9/02

    CPC classification number: G01R33/28 ,  A62B9/02 ,  F16K11/0712 ,  F16K31/122 ,  G01R33/5601

    Abstract: Methods, systems, assemblies, computer program products and devices deliver hyperpolarized gas by: (a) providing a gas delivery valve with at least one gas flow path therein, the valve comprising a valve body and at least one spool held in the valve body; (b) transmitting a pilot command fluid pulse signal to the at least one spool to introduce pressure onto the spool to force the spool to translate an actuation distance in the valve body; and (c) opening and/or closing the at least one gas flow path in response to the transmitted signal to deliver hyperpolarized gas to a subject.

    Abstract translation: 方法，系统，组件，计算机程序产品和装置通过以下方式提供超极化气体：（a）提供具有至少一个气体流路的气体输送阀，所述阀包括阀体和至少一个保持在阀体中的阀芯; （b）将先导指令流体脉冲信号传送到所述至少一个阀芯以将压力引导到所述阀芯上以迫使所述阀芯平移阀体中的致动距离; 和（c）响应于所传输的信号打开和​​/或关闭所述至少一个气体流动路径，以将超极化气体输送到对象。

    Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands
    6.
    发明申请
    Condensed indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands 失效
    缩合二氢吲哚衍生物及其用作5HT，特别是5HT2C受体配体

    公开(公告)号：US20070099980A1

    公开(公告)日：2007-05-03

    申请号：US11637036

    申请日：2006-12-12

    Applicant: Jonathan Roffey ,  James Davidson ,  Howard Mansell ,  Richard Hamlyn ,  David Adams

    Inventor： Jonathan Roffey ,  James Davidson ,  Howard Mansell ,  Richard Hamlyn ,  David Adams

    IPC: A61K31/407

    CPC classification number: C07D471/04 ,  A61K31/403 ,  A61K31/404 ,  A61K31/405 ,  A61K31/407 ,  A61K31/437 ,  A61K31/4745 ,  C07D209/60 ,  C07D209/70 ,  C07D209/90 ,  C07D471/06 ,  C07D491/04 ,  C07D491/06 ,  C07D495/04 ,  C07D495/06

    Abstract: A chemical compound of formula (I) wherein R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 and R5 are selected from hydrogen and alkyl; R6 and R7 are independently selected from hydrogen, halogen, hydroxyl, alkyl, aryl, amino, alkylamino, dialkylamino, alkoxy, aryloxy, alkylthio, alkylsulfoxyl, nitro, carbonitrile, carbo-alkoxy, carbo-aryloxy and carboxyl; and A is a 5- or 6-membered ring optionally containing one or more heteroatoms wherein the atoms of the ring A, other than the unsaturated carbon atoms of the phenyl ring to which the ring A is fused, are saturated or unsaturated, and pharmaceutically acceptable salts, addition compounds and prodrugs thereof; and the use thereof in therapy, particularly as an agonist or antagonist of a 5HT receptor, particularly a 5HT2C receptor, for instance in the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity.

    Abstract translation: 式（I）的化合物，其中R 1和R 2各自独立地选自氢和烷基; R 3是烷基; R 4和R 5选自氢和烷基; R 6和R 7独立地选自氢，卤素，羟基，烷基，芳基，氨基，烷基氨基，二烷基氨基，烷氧基，芳氧基，烷硫基，烷基亚砜基，硝基，腈 ，碳 - 烷氧基，碳 - 芳氧基和羧基; 并且A是任选地含有一个或多个杂原子的5-或6-元环，其中除了环A稠合的苯环的不饱和碳原子之外的环A的原子是饱和或不饱和的， 可接受的盐，加成化合物和前药; 以及其在治疗中的用途，特别是作为5HT受体，特别是5HT 2C受体的激动剂或拮抗剂，例如用于治疗中枢神经系统疾病; 损害中枢神经系统; 心血管疾病; 胃肠道疾病; 尿崩症和睡眠呼吸暂停，特别是用于治疗肥胖。

    Maraging steel
    8.
    发明授权
    Maraging steel 失效
    马氏体时效钢

    公开(公告)号：US6080359A

    公开(公告)日：2000-06-27

    申请号：US229566

    申请日：1999-01-13

    Applicant: James Davidson

    Inventor： James Davidson

    IPC: C22C38/00 ,  C21D8/02 ,  C22C38/06 ,  C22C38/08 ,  C22C38/12 ,  C22C38/14

    CPC classification number: C22C38/06 ,  C21D8/0205 ,  C22C38/08 ,  C22C38/12 ,  C22C38/14 ,  C21D8/0236

    Abstract: A maraging steel preferably without cobalt, having the following chemical composition: Ni 18-23 wt. %, Mo 4.5-8 wt. %, Ti 1-2 wt. %, Al 0-0.3 wt. %, C.ltoreq.0.01 wt. %, remainder Fe and impurities. The composition also preferably satisfies the following conditions:Ni+Mo=23-27 wt. %, inclusively;Ni+3.times.Mo+20.times.Ti+10.times.Al.gtoreq.60 wt. %.

    Abstract translation: 具有以下化学成分的优选不含钴的马氏体时效钢：Ni 18-23wt。 ％，Mo 4.5-8wt。 ％，Ti 1-2wt。 ％，Al 0-0.3wt。 ％，C <0.01wt。 ％，余量为Fe和杂质。 该组合物还优选满足以下条件：Ni + Mo = 23-27wt。 ％，包括; Ni + 3xMo + 20xTi + 10xAl> / = 60wt。 ％。

    Emergency vehicle warning and traffic control system
    9.
    发明授权
    Emergency vehicle warning and traffic control system 失效

    公开(公告)号：US4704610A

    公开(公告)日：1987-11-03

    申请号：US809103

    申请日：1985-12-16

    Applicant: Michel R. Smith ,  James Davidson ,  Henry Pfister

    Inventor： Michel R. Smith ,  James Davidson ,  Henry Pfister

    IPC: G08G1/0968 ,  G08G1/087 ,  G08G1/07

    CPC classification number: G08G1/087

    Abstract: A system for providing early warning of the approach and egress of emergency vehicles in which the warning system provides a display to indicate the direction from which the emergency vehicle is approaching and in addition provides preemption control of the traffic signals at an intersection. A transmitter mounted on an emergency vehicle transmits a signal whenever it is on an emergency call which is received by infrared (I.R.) receivers positioned at an intersection to respond to the transmitted signals. The received signal is then processed by a master controller which in turn pre-empts operation of traffic signals to control traffic flow at the intersection to which the emergency vehicle is approaching. The master controller also provides an output to display signs facing approaching traffic on each road approaching the intersection which displays messages and symbols indicating the direction of the approaching emergency vehicle. Additionally, the display system indicates whether the emergency vehicle has passed through and is departing the intersection. After a predetermined interval when an emergency vehicle has passed through an intersection the display system is deactivated and the traffic signals are returned to the traffic light control system.

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