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    Biochip platform including dielectric particle layer and optical assay apparatus using the same
    1.
    发明申请
    Biochip platform including dielectric particle layer and optical assay apparatus using the same 失效
    生物芯片平台包括电介质颗粒层和使用其的光学测定装置

    公开(公告)号：US20060189002A1

    公开(公告)日：2006-08-24

    申请号：US11330566

    申请日：2006-01-11

    申请人： Jang-seok Ma ,  Heon-su Jeon ,  Soo-hyung Choi ,  In-ho Lee ,  Fu Wang

    发明人： Jang-seok Ma ,  Heon-su Jeon ,  Soo-hyung Choi ,  In-ho Lee ,  Fu Wang

    IPC分类号： H01L21/00 ,  H01L21/20 ,  H01L29/82

    CPC分类号： G01N21/6428 ,  B82Y20/00

    摘要： Provided are a biochip platform for biochemically analyzing a sample such as DNA or protein, including a dielectric particle layer, and an optical assay apparatus including the same. The biochip platform includes the dielectric particle layer uniformly formed on a substrate. The particle uniformity of the dielectric particle layer enables good wavelength separation of fluorescence signal, and the large surface area of the dielectric particle layer guarantees better amplification efficiency of fluorescence signal. Furthermore, the biochip platform shows good economical efficiency due to easy fabrication process, and is particularly useful in an optical assay apparatus for analyzing a biochemical sample due to good assay efficiency.

    摘要翻译： 提供了用于生物化学分析诸如DNA或蛋白质的样品（包括电介质颗粒层）的生物芯片平台和包括其的光学测定装置。 生物芯片平台包括均匀地形成在基板上的电介质颗粒层。 电介质颗粒层的粒子均匀性使得荧光信号的波长分离良好，并且电介质颗粒层的大的表面积保证了荧光信号的更好的放大效率。 此外，生物芯片平台由于易于制造工艺而显示出良好的经济效率，并且在由于良好的测定效率分析生物化学样品的光学测定装置中特别有用。

    Biochip platform including dielectric particle layer and optical assay apparatus using the same
    2.
    发明授权
    Biochip platform including dielectric particle layer and optical assay apparatus using the same 失效
    生物芯片平台包括电介质颗粒层和使用其的光学测定装置

    公开(公告)号：US07662614B2

    公开(公告)日：2010-02-16

    申请号：US11330566

    申请日：2006-01-11

    申请人： Jang-seok Ma ,  Heon-su Jeon ,  Soo-hyung Choi ,  In-ho Lee ,  Fu Wang

    发明人： Jang-seok Ma ,  Heon-su Jeon ,  Soo-hyung Choi ,  In-ho Lee ,  Fu Wang

    IPC分类号： C12M1/34

    CPC分类号： G01N21/6428 ,  B82Y20/00

    摘要： Provided are a biochip platform for biochemically analyzing a sample such as DNA or protein, including a dielectric particle layer, and an optical assay apparatus including the same. The biochip platform includes the dielectric particle layer uniformly formed on a substrate. The particle uniformity of the dielectric particle layer enables good wavelength separation of fluorescence signal, and the large surface area of the dielectric particle layer guarantees better amplifications efficiency of fluorescence signal. Furthermore, the biochip platform shows good economical efficiency due to easy fabrication process, and is particularly useful in an optical assay apparatus for analyzing a biochemical sample due to good assay efficiency.

    摘要翻译： 提供了用于生物化学分析诸如DNA或蛋白质的样品（包括电介质颗粒层）的生物芯片平台和包括其的光学测定装置。 生物芯片平台包括均匀地形成在基板上的电介质颗粒层。 电介质颗粒层的粒子均匀性使得荧光信号的波长分离良好，并且电介质颗粒层的大的表面积保证了荧光信号的更好的放大效率。 此外，生物芯片平台由于易于制造工艺而显示出良好的经济效率，并且在由于良好的测定效率分析生物化学样品的光学测定装置中特别有用。

    Optical detection device
    3.
    发明授权
    Optical detection device 有权
    光学检测装置

    公开(公告)号：US07330264B2

    公开(公告)日：2008-02-12

    申请号：US11071819

    申请日：2005-03-03

    申请人： Jang-seok Ma ,  Fu Wang ,  In-jae Lee ,  Soo-suk Lee ,  Young-nam Kwon ,  Young-hoon Kim ,  Hui-jun Sim ,  In-ho Lee ,  Young-hwan Lee

    发明人： Jang-seok Ma ,  Fu Wang ,  In-jae Lee ,  Soo-suk Lee ,  Young-nam Kwon ,  Young-hoon Kim ,  Hui-jun Sim ,  In-ho Lee ,  Young-hwan Lee

    IPC分类号： G01N21/55

    CPC分类号： G01N21/648 ,  G01N21/6454

    摘要： An optical detection device for biochemically analyzing samples of microfluidic chips such as DNA chips or protein chips is provided. The optical detection device includes a light source for generating excitation light to excite a sample, a detection plate having an optical waveguide with the sample mounted thereon, a linear symmetry lens for shaping the excitation light into a desired shape having a uniform intensity distribution and transmitting it to the detection plate, and a detector for detecting radiation from the sample.

    摘要翻译： 提供了用于生物化学分析诸如DNA芯片或蛋白质芯片之类的微流体芯片的样品的光学检测装置。 光学检测装置包括用于产生激发光以激发样品的光源，具有安装有样品的光波导的检测板，用于将激发光成形为具有均匀强度分布和传输的所需形状的线性对称透镜 检测板，以及用于检测来自样品的辐射的检测器。

    Optical detection device
    4.
    发明申请
    Optical detection device 有权
    光学检测装置

    公开(公告)号：US20050195394A1

    公开(公告)日：2005-09-08

    申请号：US11071819

    申请日：2005-03-03

    申请人： Jang-seok Ma ,  Fu Wang ,  In-jae Lee ,  Soo-suk Lee ,  Young-nam Kwon ,  Young-hoon Kim ,  Hui-jun Sim ,  In-ho Lee ,  Young-hwan Lee

    发明人： Jang-seok Ma ,  Fu Wang ,  In-jae Lee ,  Soo-suk Lee ,  Young-nam Kwon ,  Young-hoon Kim ,  Hui-jun Sim ,  In-ho Lee ,  Young-hwan Lee

    IPC分类号： G01J3/30 ,  G01N21/64

    CPC分类号： G01N21/648 ,  G01N21/6454

    摘要： An optical detection device for biochemically analyzing samples of microfluidic chips such as DNA chips or protein chips is provided. The optical detection device includes a light source for generating excitation light to excite a sample, a detection plate having an optical waveguide with the sample mounted thereon, a linear symmetry lens for shaping the excitation light into a desired shape having a uniform intensity distribution and transmitting it to the detection plate, and a detector for detecting radiation from the sample.

    摘要翻译： 提供了用于生物化学分析诸如DNA芯片或蛋白质芯片之类的微流体芯片的样品的光学检测装置。 光学检测装置包括用于产生激发光以激发样品的光源，具有安装有样品的光波导的检测板，用于将激发光成形为具有均匀强度分布和传输的所需形状的线性对称透镜 检测板，以及用于检测来自样品的辐射的检测器。

    Method of separating biomolecules using nanopore
    8.
    发明申请
    Method of separating biomolecules using nanopore 审中-公开
    使用纳米孔分离生物分子的方法

    公开(公告)号：US20060183112A1

    公开(公告)日：2006-08-17

    申请号：US11335246

    申请日：2006-01-19

    申请人： Jun-hong Min ,  Su-hyeon Kim ,  In-ho Lee ,  Kui-hyun Kim ,  Seung-yeon Yang

    发明人： Jun-hong Min ,  Su-hyeon Kim ,  In-ho Lee ,  Kui-hyun Kim ,  Seung-yeon Yang

    IPC分类号： C12Q1/70 ,  C12Q1/68

    CPC分类号： G01N33/5438 ,  G01N33/48721

    摘要： Provided is a method of separating particles, the method comprising: forming a first chamber and a second chamber separated by an interface with a pore, wherein the first and second chambers have electrodes with different polarities; placing particles to which a target biomolecule is bound from particles to which the target biomolecule is not bound in the first chamber; applying a voltage which has the same polarity as that of the target biomolecule to the electrode of the first chamber, and a voltage which has an opposite charge to that of the target biomolecule to the electrode of the second chamber; and translocating only the particles to which the target biomolecule is bound from the first chamber to the second chamber through the pore. Conventionally, the size of a pore is used to separate biomolecules. However, effective separation is difficult to achieve because the manufacture of a pore with a diameter of less than 10 nm, small enough to separate biomolecule, is not easy. Therefore, signal separation and data analysis must be required. However, in the present method, physical movement induced by the charge of biomolecules is used to effectively separate the biomolecules, thus obtaining a high signal to noise ratio. As a result, additional data analysis is not required.

    摘要翻译： 提供了一种分离颗粒的方法，该方法包括：形成由与孔的界面分隔开的第一室和第二室，其中第一和第二室具有不同极性的电极; 在第一室中放置靶生物分子所结合的颗粒与目标生物分子不结合的颗粒; 将具有与目标生物分子相同极性的电压施加到第一室的电极，以及将具有与靶生物分子相反的电荷的电压施加到第二室的电极; 并且仅将来自第一室的目标生物分子结合的颗粒通过孔转移到第二室。 通常，使用孔的大小来分离生物分子。 然而，由于直径小于10nm的孔的制造足够小以分离生物分子，所以难以实现有效的分离，这是不容易的。 因此，必须要求信号分离和数据分析。 然而，在本方法中，由生物分子的电荷引起的身体运动用于有效分离生物分子，从而获得高的信噪比。 因此，不需要额外的数据分析。

    Electrodialysis apparatus and electrodialysis method using the same
    9.
    发明授权
    Electrodialysis apparatus and electrodialysis method using the same 有权
    电渗析装置及使用其的电渗析方法

    公开(公告)号：US08343325B2

    公开(公告)日：2013-01-01

    申请号：US11737448

    申请日：2007-04-19

    申请人： Hun-joo Lee ,  Soo-suk Lee ,  Joon-ho Kim ,  Sung-ouk Jung ,  In-ho Lee

    发明人： Hun-joo Lee ,  Soo-suk Lee ,  Joon-ho Kim ,  Sung-ouk Jung ,  In-ho Lee

    IPC分类号： B01D61/44

    CPC分类号： B01D61/422 ,  B01D2311/243 ,  B01D2313/02 ,  B01D2313/10 ,  B01D2313/26 ,  B01D2313/30 ,  B01D2313/50 ,  B01D2321/185

    摘要： An electrodialysis apparatus includes a sample chamber including first and second dialysis membranes and filled with a sample between the first dialysis membrane and the second dialysis membrane, an anode chamber including an anode and filled with a first chamber solution between the anode and the first dialysis membrane, and a cathode chamber including a cathode and filled with a second chamber solution between the cathode and the second dialysis membrane. In particular, when a voltage is applied to the anode and the cathode, ionic materials of the sample move to the anode and cathode chambers.

    摘要翻译： 电渗透装置包括：样品室，包括第一和第二透析膜，并在第一透析膜和第二透析膜之间填充样品;阳极室，包括阳极，并在阳极和第一透析膜之间填充第一室溶液 以及包括阴极并在阴极和第二透析膜之间填充有第二室溶液的阴极室。 特别地，当向阳极和阴极施加电压时，样品的离子材料移动到阳极室和阴极室。

    Coupling apparatus of wiper arm
    10.
    发明授权
    Coupling apparatus of wiper arm 有权
    雨刷臂联轴器

    公开(公告)号：US07832046B2

    公开(公告)日：2010-11-16

    申请号：US11571927

    申请日：2006-10-26

    申请人： In-ho Lee ,  Yeong-ki Min ,  Sung-wook Jeon ,  Nam-young Suk ,  Weiler Michael ,  Philip Claeskens

    发明人： In-ho Lee ,  Yeong-ki Min ,  Sung-wook Jeon ,  Nam-young Suk ,  Weiler Michael ,  Philip Claeskens

    IPC分类号： B60S1/40

    CPC分类号： B60S1/40 ,  B60S1/4064 ,  B60S2001/409

    摘要： Disclosed herein is a coupling apparatus for a wiper arm, which can provide firm coupling between a wiper blade and the wiper arm. The coupling apparatus comprises a blade coupling part provided to the wiper blade and including front and rear plates and having an opening defined at upper portions of the front and rear plates and a support shaft having a rectilinear plane formed at either side of the support shaft, and a wiper arm coupling part integrally formed at one end with the wiper arm and including a slant insertion mechanism to cause the wiper arm to be slantly inserted onto the support shaft and to hold the support shaft so as not to be separated from the slant insertion mechanism by changing an inclination of the wiper arm after the wiper arm is inserted onto the support shaft.

    摘要翻译： 这里公开了一种用于刮水器臂的联接装置，其能够提供刮水器刮片和刮水器臂之间的牢固的联接。 联接装置包括设置在刮水片上的叶片联接部，包括前板和后板，并且具有限定在前板和后板的上部的开口和具有形成在支撑轴的任一侧的直线平面的支撑轴， 以及在一端与刮水器臂一体形成的刮水器臂联接部，并且包括倾斜插入机构，以使刮水臂倾斜地插入到支撑轴上并且保持支撑轴，以便不与倾斜插入物分离 通过在雨刷臂插入到支撑轴上之后改变雨刷臂的倾斜度的机构。