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    NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM
    4.
    发明申请
    NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM 审中-公开
    核酸和蛋白质及其制备和使用方法

    公开(公告)号：US20110296543A1

    公开(公告)日：2011-12-01

    申请号：US12324436

    申请日：2008-11-26

    申请人： Hwai Chang ,  Eric J. Mathur ,  Michelle Cayouette ,  Dan E. Robertson ,  Philip Hugenholtz ,  Falk Warnecke ,  Jared R. Leadbetter ,  Natalia Ivanova ,  Peter Luginbuhl ,  Don Hutchison

    发明人： Hwai Chang ,  Eric J. Mathur ,  Michelle Cayouette ,  Dan E. Robertson ,  Philip Hugenholtz ,  Falk Warnecke ,  Jared R. Leadbetter ,  Natalia Ivanova ,  Peter Luginbuhl ,  Don Hutchison

    IPC分类号： A01K67/00

    CPC分类号： C12Y302/01015 ,  C12N9/2437 ,  C12Y302/01004 ,  C12Y302/01006 ,  C12Y302/01039 ,  C12Y302/01067 ,  C12Y302/01082

    摘要： The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.

    摘要翻译： 本发明提供了多肽，包括酶，结构蛋白和结合蛋白，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 本发明的多肽，包括酶和抗体以及核酸可用于工业，实验，食品和饲料加工，营养和药物应用中，例如用于食品和饲料添加剂，着色剂，中性药物，化妆品和药物需求。 本发明的多肽可用于食品加工，酿造，浴添加剂，酒精生产，肽合成，对映选择性，皮革行业中的皮革制备，废物管理和动物降解，摄影工业中的银回收，医疗，丝绸脱胶， 生物膜降解，生物燃料转化为生物燃料（例如生物乙醇，生物甲醇，生物丙醇或生物丁醇，生物柴油等），生物防治剂，抗微生物剂和消毒剂，个人护理和化妆品，生物技术试剂，玉米湿法研磨和药物如 消化助剂和抗炎（抗炎）药剂。

    Proteases, nucleic acids encoding them and methods for making and using them
    6.
    发明授权
    Proteases, nucleic acids encoding them and methods for making and using them 有权
    蛋白酶，编码它们的核酸和制备和使用它们的方法

    公开(公告)号：US07642079B2

    公开(公告)日：2010-01-05

    申请号：US10530643

    申请日：2003-10-10

    申请人： Michelle Cayouette ,  Connie Jo Hansen ,  Amy McClure ,  May Sun ,  Svetlana Gramatikova ,  Mark Dycaico ,  Nelson R. Barton ,  Justin T. Stege ,  Nahla M. Aboushadi

    发明人： Michelle Cayouette ,  Connie Jo Hansen ,  Amy McClure ,  May Sun ,  Svetlana Gramatikova ,  Mark Dycaico ,  Nelson R. Barton ,  Justin T. Stege ,  Nahla M. Aboushadi

    IPC分类号： C12N9/48

    CPC分类号： C12N9/52 ,  A01K2217/05

    摘要： The invention is directed to polypeptides having protease activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of diagnostic, therapeutic, and industrial contexts. The polypeptides of the invention can be used as, e.g., an additive for a detergent, for processing foods and for chemical synthesis utilizing a reverse reaction. Additionally, the polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to ethanol diodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in increasing starch yield from corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.

    摘要翻译： 本发明涉及具有蛋白酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 本发明的多肽可用于多种诊断，治疗和工业背景。 本发明的多肽可用作例如用于洗涤剂的添加剂，用于加工食品和利用反向反应进行化学合成。 此外，本发明的多肽可用于食品加工，酿造，浴添加剂，醇生产，肽合成，对映选择性，皮革工业中的皮革制备，废物管理和动物降解，摄影工业中的银回收，医疗， 丝绸脱胶，生物膜降解，生物质转化为乙醇二聚体，抗微生物剂和消毒剂，个人护理和化妆品，生物技术试剂，用于增加玉米湿法研磨的淀粉产量，以及药物如消化助剂和抗炎（抗炎）剂。

    Proteases, nucleic acids encoding them and methods for making and using them
    7.
    发明申请
    Proteases, nucleic acids encoding them and methods for making and using them 有权
    蛋白酶，编码它们的核酸和制备和使用它们的方法

    公开(公告)号：US20060259995A1

    公开(公告)日：2006-11-16

    申请号：US10530643

    申请日：2003-10-10

    申请人： Michelle Cayouette ,  Connie Hansen ,  Amy McClure ,  May Sun ,  Svetlana Gramatikova ,  Mark Dycaico ,  Nelson Barton ,  Justin Stege ,  Nahla Aboushadi

    发明人： Michelle Cayouette ,  Connie Hansen ,  Amy McClure ,  May Sun ,  Svetlana Gramatikova ,  Mark Dycaico ,  Nelson Barton ,  Justin Stege ,  Nahla Aboushadi

    IPC分类号： A01K67/027 ,  C12Q1/68 ,  C07H21/04 ,  C12P21/06 ,  C12N9/64 ,  A01H1/00

    CPC分类号： C12N9/52 ,  A01K2217/05

    摘要： The invention is directed to polypeptides having protease activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of diagnostic, therapeutic, and industrial contexts. The polypeptides of the invention can be used as, e.g., an additive for a detergent, for processing foods and for chemical synthesis utilizing a reverse reaction. Additionally, the polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to ethanol diodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in increasing starch yield from corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.

    摘要翻译： 本发明涉及具有蛋白酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 本发明的多肽可用于多种诊断，治疗和工业背景。 本发明的多肽可用作例如用于洗涤剂的添加剂，用于加工食品和利用反向反应进行化学合成。 此外，本发明的多肽可用于食品加工，酿造，浴添加剂，醇生产，肽合成，对映选择性，皮革工业中的皮革制备，废物管理和动物降解，摄影工业中的银回收，医疗， 丝绸脱胶，生物膜降解，生物质转化为乙醇二聚体，抗微生物剂和消毒剂，个人护理和化妆品，生物技术试剂，用于增加玉米湿法研磨的淀粉产量，以及药物如消化助剂和抗炎（抗炎）剂。