Aliphatic polyester polymer compositions and preparation method thereof
    4.
    发明申请
    Aliphatic polyester polymer compositions and preparation method thereof 有权
    脂肪族聚酯聚合物组合物及其制备方法

    公开(公告)号:US20070155943A1

    公开(公告)日:2007-07-05

    申请号:US11606918

    申请日:2006-12-01

    IPC分类号: C08G18/42

    摘要: An aliphatic polyester polymer compositions and preparation method thereof. The invention provides a bioresorbable aliphatic polyester copolymer, comprising the reaction product of a first polyester, a second polyester, and a coupling agent. Specifically, the first polyester and second polyester have the same repeat units, but different weight average molecular weights. Methods for preparing the aliphatic polyester copolymer are provided, in which the first polyester reacts with the second polyester in the presence of the coupling agent, undergoing copolymerization.

    摘要翻译: 脂肪族聚酯聚合物组合物及其制备方法。 本发明提供了生物可再吸收的脂族聚酯共聚物,其包含第一聚酯,第二聚酯和偶联剂的反应产物。 具体地说,第一聚酯和第二聚酯具有相同的重复单元,但是重均分子量不同。 提供了制备脂族聚酯共聚物的方法,其中第一聚酯在偶联剂存在下与第二聚酯反应进行共聚。

    Toilet flushing device
    7.
    发明授权

    公开(公告)号:US5175894A

    公开(公告)日:1993-01-05

    申请号:US830306

    申请日:1992-01-31

    申请人: Jui-Hsiang Chen

    发明人: Jui-Hsiang Chen

    IPC分类号: E03D1/36 E03D3/00 E03D5/00

    摘要: A toilet flushing device has a diverter valve which permits the supply of high pressure water to the rim flushing conduit of a toilet bowl when the toilet bowl is flushed, thereby enhancing the flushing of the toilet bowl. The diverter valve has provisions for adjusting the level of refill water inside the toilet bowl so as to help reduce water consumption.

    Method for producing cross-linked hyaluronic acid-protein bio-composites
    9.
    发明申请
    Method for producing cross-linked hyaluronic acid-protein bio-composites 审中-公开
    交联透明质酸 - 蛋白质生物复合材料的制备方法

    公开(公告)号:US20060189516A1

    公开(公告)日:2006-08-24

    申请号:US11208596

    申请日:2005-08-23

    IPC分类号: A61K38/16 C07K14/47

    CPC分类号: A61L27/58 A61L27/20 C08L5/08

    摘要: This invention is concerned with a new method for producing cross-linked hyaluronic acid—protein bio-composites in various shapes. In the present process, a polysaccharide solution and a protein solution are mixed under moderate pH values in presence of salts to form a homogenous solution, which can be processed into various shapes, such as membrane, sponge, fiber, tube or micro-granular and so on. After then, the homogenous solution is subjected to a cross-linking reaction in organic solvent containing weak acid to produce an implantable bio composite material having excellent bio-compatibility, biodegradability, prolonged enzymatic degradation time, and good physical properties.

    摘要翻译: 本发明涉及用于生产各种形状的交联透明质酸 - 蛋白质生物复合材料的新方法。 在本方法中,多糖溶液和蛋白质溶液在盐的存在下在中等pH值下混合以形成均匀的溶液,其可以加工成各种形状,例如膜,海绵,纤维,管或微粒,以及 所以。 然后,均匀溶液在含有弱酸的有机溶剂中进行交联反应,生成具有优异的生物相容性,生物降解性,延长的酶降解时间和良好物理性质的可植入生物复合材料。

    Biodegradable copolymer, and polymeric micelle composition containing the same
    10.
    发明申请
    Biodegradable copolymer, and polymeric micelle composition containing the same 有权
    生物可降解共聚物和含有它们的聚合胶束组合物

    公开(公告)号:US20050019303A1

    公开(公告)日:2005-01-27

    申请号:US10745975

    申请日:2003-12-29

    摘要: A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.

    摘要翻译: 具有芯块的可生物降解的共聚物,其包含生物可再吸收的疏水性聚酯链段和包含亲水性聚乙二醇链段的3至10个壳嵌段。 疏水性聚酯链段和亲水性聚乙二醇链段各自通过氨基甲酸酯键连接。 还提供含有该共聚物的聚合胶束组合物。 当共聚物在分散介质中的浓度达到或超过临界胶束浓度时,共聚物形成胶束。 胶束具有良好的药物和生物活性剂递送特性,适用于药物递送或化妆品应用。