摘要:
Ultrasonic sonothrombolysis systems to produce two acoustic pressure levels of insonation during stroke therapy, mid/high acoustic pressure insonation directed to the site of a blood clot where microbubbles are present to induce microbubble-mediated blood clot lysis, and low acoustic insonation directed to the region surrounding the site of the blood clot where microbubbles are present to stimulate microvascular reperfusion of the surrounding tissue. The systems simultaneously produce blood clot lysis at the site of an occlusion and stimulate reperfusion of tissue affected by the occlusion.
摘要:
A HIFU System (100) is disclosed which may automatically generate a proposed treatment plan for treating a tissue treatment area (10) with HIFU Therapy. In one example, the proposed treatment plan includes a plurality of treatment sites selected based on a three-dimensional model generated from ultrasound data. In another example, the proposed treatment plan excludes portions of the tissue treatment area (10) corresponding to blood flow, such as the neuro-vascular bundles (20) when treating the prostate (11).
摘要:
Ultrasound transducers are disclosed which focus acoustic energy at various focal locations while minimizing focal spot degradation and the generation of unwanted on-axis or off-axis energy concentrations through using a generally constant f-number at the various focal locations.
摘要:
A method of diagnosis and treatment of tumors using High Intensity Focused Ultrasound is provided. The method of diagnosing the presence of a tumor in a patient comprises the steps of subjecting a tumor to high intensity focused ultrasound (HIFU) to cause the tumor cells to release cellular material and evaluating the cellular material for a tumor marker. The method of treating a tumor in a patient can also comprise the step of subjecting a tumor to high intensity focused ultrasound (HIFU) to provoke an immune response.
摘要:
Method, apparatus and computer programs are described for compensating for the effect of temperature on the sensitivity of electrostatic ultrasound (US) transducers, particularly as used in an automotive occupancy sensing (AOS) systems for sensing the nature or type of occupant and the location of the occupant with respect to the vehicle interior. The invention permits the AOS to classify the occupancy state of the vehicle from a US echo signal substantially free of the effects of temperature on signal amplitude. A capacitive divider or voltage monitor is employed to measure the capacitance of the transducer. The voltage monitor output is used by the scaling algorithm of a compensator to determine the scaling factor to be applied to the US transducer signal to compensate for the effect of temperature on the transducer sensitivity. Calibration procedures and software are disclosed for determining the coefficients of the scaling algorithm to compensate for temperature effects and also to compensate for installation factors, transducer manufacturing variations, and circuit board effects. The system disclosed is useful for other types of signal processing in addition to temperature compensation of AOS ultrasonic signals, and may be used in other ranging devices such as cameras, golf or binocular range finders, and measuring devices and instruments.
摘要:
Method, apparatus and computer programs are described for compensating for the effect of temperature on the sensitivity of electrostatic ultrasound (US) transducers, particularly as used in an automotive occupancy sensing (AOS) systems for sensing the nature or type of occupant and the location of the occupant with respect to the vehicle interior. The invention permits the AOS to classify the occupancy state of the vehicle from a US echo signal substantially free of the effects of temperature on signal amplitude. A capacitive divider or voltage monitor is employed to measure the capacitance of the transducer. The voltage monitor output is used by the scaling algorithm of a compensator to determine the scaling factor to be applied to the US transducer signal to compensate for the effect of temperature oil the transducer sensitivity. Calibration procedures and software are disclosed for determining the coefficients of the scaling algorithm to compensate for temperature effects and also to compensate for installation factors, transducer manufacturing variations, and circuit board effects. The system disclosed is useful for other types of signal processing in addition to temperature compensation of AOS ultrasonic signals, and may be used in other ranging devices such as cameras, golf or binocular range finders, and measuring devices and instruments.
摘要:
Bubble presence within a region is monitored to determine if a predetermined condition is met such as whether the presence is of sufficient magnitude, the bubbles being subject to energizing (240). In some embodiments, the energizing only occurs when time- wise preceded by the determination (S508, S510). The determining can include measuring a grayscale value (104), or assessing the energy carried by a frequency component of the echo signal, in the region in real time. The energizing may occur region-by-region, automatically and without need for user intervention, in a treatment pass (S428) over the regions. The regions (232) in the pass might be subject to respective instances of the energizing without intervening monitoring, or, in another embodiment, to both the determining and the responsive energizing. The determining can be subject to, automatically and without need for user intervention, interruption (S408) and concurrent switching to a next region.
摘要:
In one variation, a temperature-maintenance device includes a heater (1016) and is placeable in a circulation loop of an ultrasound transducer coupling bolus (1076), for degassing circulating liquid of the loop and for operating the heater for performing temperature control of the liquid. A temperature setpoint, such as a normal body temperature, for the liquid at the bolus may be entered. A device, either open- or closed-looped with respect to fluid flow, may include, in some variations, a degassing chamber, a water trap (1012), and an intervening cooler, all vacuumized by a vacuum pump (1024). The chamber may be configured and aligned for letting condensation automatically drain out. The water trap may be emptied, automatically and without the need for user intervention, by a motorized trap emptier and/or be emptiable by the user.