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    ENZYMATIC PRODUCTION OF FATTY ACID ETHYL ESTERS
    1.
    发明申请
    ENZYMATIC PRODUCTION OF FATTY ACID ETHYL ESTERS 审中-公开
    脂肪酸乙酯的生产

    公开(公告)号：US20110219675A1

    公开(公告)日：2011-09-15

    申请号：US13125189

    申请日：2009-10-29

    申请人： Jesper Brask ,  Per Munk Nielsen ,  Yuan Xu

    发明人： Jesper Brask ,  Per Munk Nielsen ,  Yuan Xu

    IPC分类号： C10L1/02 ,  C12P7/64

    CPC分类号： C12P7/649 ,  Y02E50/13

    摘要： The invention relates to a method of producing fatty acid ethyl esters comprising: a) reacting a substrate comprising triglycerides, diglycerides, monoglycerides, free fatty acids, or any combination thereof, with at least one immobilized lipolytenzyme, to provide a reaction mixture wherein the enzyme loading is below 30% w/w with respect to the substrate, and the molar ratio of ethanol to fatty acid (EtOH:FA) is at least 3.0 equivalents; b) separating the immobilized lipolytic enzyme from the resulting reaction mixture; and c) subjecting the immobilized lipolytic enzyme to at least one further reaction directly without modifications.

    摘要翻译： 本发明涉及一种生产脂肪酸乙酯的方法，包括：a）使包含甘油三酯，甘油二酯，甘油单酯，游离脂肪酸或其任何组合的底物与至少一种固定化的脂解酶进行反应，以提供反应混合物，其中所述酶 载体相对于底物低于30％w / w，乙醇与脂肪酸（EtOH：FA）的摩尔比为至少3.0当量; b）从所得反应混合物中分离固定化的脂肪分解酶; 和c）直接将固定化的脂肪分解酶进行至少一种其他反应而无需修改。

    Silicone hydrogel contact lenses
    2.
    发明授权
    Silicone hydrogel contact lenses 有权
    硅胶水凝胶隐形眼镜

    公开(公告)号：US09296159B2

    公开(公告)日：2016-03-29

    申请号：US13983306

    申请日：2012-02-23

    申请人： Ying Zheng ,  Yuan Xu ,  Junhao Ge ,  Charles A. Francis ,  Yuan Sun ,  Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Hongjin Qiu ,  Li Yao ,  Arthur Back

    发明人： Ying Zheng ,  Yuan Xu ,  Junhao Ge ,  Charles A. Francis ,  Yuan Sun ,  Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Hongjin Qiu ,  Li Yao ,  Arthur Back

    IPC分类号： G02B1/04 ,  B29D11/00 ,  C08F290/06

    CPC分类号： B29D11/00125 ,  B29D11/0025 ,  C08F290/068 ,  G02B1/043 ,  C08L83/04 ,  C08L101/14

    摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

    摘要翻译： 衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在 在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于 可聚合组合物的含量为1〜20单位重量份。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

    Silicone Hydrogel Contact Lenses
    4.
    发明申请
    Silicone Hydrogel Contact Lenses 有权
    硅胶水凝胶隐形眼镜

    公开(公告)号：US20140009735A1

    公开(公告)日：2014-01-09

    申请号：US13983306

    申请日：2012-02-23

    申请人： Ying Zheng ,  Yuan Xu ,  Junhao Ge ,  Charles A. Francis ,  Yuan Sun ,  Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Hongjin Qiu ,  Li Yao ,  Arthur Back

    发明人： Ying Zheng ,  Yuan Xu ,  Junhao Ge ,  Charles A. Francis ,  Yuan Sun ,  Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Hongjin Qiu ,  Li Yao ,  Arthur Back

    IPC分类号： G02B1/04 ,  B29D11/00

    CPC分类号： B29D11/00125 ,  B29D11/0025 ,  C08F290/068 ,  G02B1/043 ,  C08L83/04 ,  C08L101/14

    摘要： Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer, or at least one hydrophilic vinyl ether-containing monomer, or both, wherein, when the at least one hydrophobic ethylene glycol methyl ether methacrylate-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, and when the at least one hydrophilic vinyl ether-containing monomer is present in the polymerizable composition, it is present in an amount of from 1 to 20 unit parts by weight, are described. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

    摘要翻译： 衍生自包含至少一种硅氧烷单体和至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体或至少一种亲水乙烯基醚的单体或两者的可聚合组合物的硅氧烷水凝胶隐形眼镜，其中当在 在可聚合组合物中存在至少一种疏水性乙二醇甲基醚甲基丙烯酸酯单体，其存在量为1至20单位份重量，并且当至少一种亲水乙烯基醚单体存在于 可聚合组合物的含量为1〜20单位重量份。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

    Dimensionally Stable Silicone Hydrogel Contact Lenses
    6.
    发明申请
    Dimensionally Stable Silicone Hydrogel Contact Lenses 有权
    尺寸稳定的硅胶水凝胶隐形眼镜

    公开(公告)号：US20120220743A1

    公开(公告)日：2012-08-30

    申请号：US13404034

    申请日：2012-02-24

    申请人： Charles A. Francis ,  Ying Zheng ,  Yuan Xu ,  Li Yao ,  Arthur Back ,  Ye Hong ,  Charlie Chen

    发明人： Charles A. Francis ,  Ying Zheng ,  Yuan Xu ,  Li Yao ,  Arthur Back ,  Ye Hong ,  Charlie Chen

    IPC分类号： C08F230/08

    CPC分类号： C08F230/08 ,  C08F222/1006

    摘要： Dimensionally stable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer represented by formula (2): wherein R1 of formula (2) is selected from either hydrogen atom or a methyl group; R2 of formula (2) is selected from either of hydrogen atom or a hydrocarbon group having 1 to 4 carbon atoms; m of formula (2) represents an integer of from 0 to 10; n of formula (2) represents an integer of from 4 to 100; a and b represent integers of 1 or more; a+b is equal to 20-500; b/(a+b) is equal to 0.01-0.22; the configuration of siloxane units includes a random configuration, the second siloxane monomer having a number average molecular weight of at least 3,000 daltons that is present in the polymerizable composition in an amount such that ratio of the first siloxane monomer to the second siloxane monomer is at least 2:1 based on unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

    摘要翻译： 描述了尺寸稳定的硅酮水凝胶隐形眼镜。 透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。 透镜还包括衍生自由式（2）表示的第二硅氧烷单体的单元：其中式（2）的R 1选自氢原子或甲基; 式（2）的R2选自氢原子或碳原子数为1〜4的烃基; 式（2）的m表示0〜10的整数， 式（2）的n表示4〜100的整数， a和b表示1以上的整数; a + b等于20-500; b /（a + b）等于0.01-0.22; 硅氧烷单元的构型包括随机构型，第二硅氧烷单体的数均分子量为至少3,000道尔顿，其存在于可聚合组合物中，其量使得第一硅氧烷单体与第二硅氧烷单体的比率在 至少2：1，单位重量份。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

    RECONSTRUCTING A TOMOGRAPHIC IMAGE WITH REDUCED ARTIFACTS
    8.
    发明申请
    RECONSTRUCTING A TOMOGRAPHIC IMAGE WITH REDUCED ARTIFACTS 失效
    用减少的人造成重建图像

    公开(公告)号：US20110266453A1

    公开(公告)日：2011-11-03

    申请号：US13132841

    申请日：2009-12-04

    申请人： Oleg Tischenko ,  Yuan Xu ,  Christoph Hoeschen

    发明人： Oleg Tischenko ,  Yuan Xu ,  Christoph Hoeschen

    IPC分类号： G01T1/00 ,  G06K9/36

    CPC分类号： G06T11/008 ,  A61B6/027 ,  G06T11/005

    摘要： A method of reconstructing a tomographic image of a region of investigation with reduced artifacts, said method comprises the steps of (a) reconstructing a first partial image and a second partial image of the region of investigation from first and second projection profiles each of which including projection data collected at first and second different groups of parallel projection lines, resp., wherein the first and second projection profiles are provided such that streak aliasing artifacts in the first and second partial images have different spatial phases, and (b) generating the tomographic image of the region of investigation by superimposing the first and second partial images. Preferably, the first and second projection profiles are constructed such that streak aliasing artifacts in the first and second partial images have opposite spatial phases relative to each other. Furthermore, an imaging method and an imaging device for imaging a region of investigation in an object are described.

    摘要翻译： 一种利用减少的伪像来重建调查区域的断层图像的方法，所述方法包括以下步骤：（a）从第一和第二投影轮廓重建调查区域的第一部分图像和第二部分图像，每个投影图包括 在第一和第二不同组的平行投影线上收集的投影数据，其中提供第一和第二投影轮廓，使得第一和第二部分图像中的条纹混叠伪影具有不同的空间相位，以及（b）产生断层图像 通过叠加第一和第二部分图像的调查区域的图像。 优选地，第一和第二投影轮廓被构造成使得第一和第二部分图像中的条纹混叠伪像相对于彼此具有相反的空间相位。 此外，描述了用于对物体中的调查区域进行成像的成像方法和成像装置。

    RESIST ADHENSION TO CARBON OVERCOATS FOR NANOIMPRINT LITHOGRAPHY
    9.
    发明申请
    RESIST ADHENSION TO CARBON OVERCOATS FOR NANOIMPRINT LITHOGRAPHY 审中-公开
    碳纳米尺度对碳纳米管的耐蚀性

    公开(公告)号：US20110195276A1

    公开(公告)日：2011-08-11

    申请号：US12703887

    申请日：2010-02-11

    申请人： Wei Hu ,  Nobuo Kurataka ,  Yuan Xu ,  Gennady Gauzner

    发明人： Wei Hu ,  Nobuo Kurataka ,  Yuan Xu ,  Gennady Gauzner

    IPC分类号： G11B5/702 ,  B05D5/08 ,  B05D3/12

    CPC分类号： G11B5/855 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

    摘要： In an imprint lithography process, a carbon overcoat (COC) layer has nitrogen introduced into an upper surface region thereof before application of an adhesion layer to the COC/substrate combination. This results in the formation of a thin layer of nitrogenated carbon at the surface of the COC layer that promotes covalent bonding with the functional groups of the adhesion layer and, thus, significantly improves resist adhesion upon imprint template removal. Thus, an embodiment of an imprint lithography method comprises introducing nitrogen into an upper surface region of the COC layer, forming an adhesion layer on the nitrogenated COC layer, forming resist on the adhesion layer, contacting the resist with an imprint template having patterned features formed therein such that the resist fills the patterned features of the imprint template, and separating the imprint template from the resist such that a negative image of the patterned features is formed in the resist. An embodiment of an imprint structure comprises a substrate, a COC layer formed on the substrate, the COC layer having a nitrogenated upper surface region formed therein, and adhesion layer formed on the COC layer, and resist formed on the adhesion layer.

    摘要翻译： 在压印光刻工艺中，在向COC /衬底组合施加粘附层之前，碳覆盖层（COC）层将氮气引入其上表面区域。 这导致在COC层的表面上形成薄层的氮化碳，其促进与粘合层的官能团的共价键，并且因此显着提高印模模板去除时的抗附着力。 因此，压印光刻方法的一个实施例包括将氮气引入COC层的上表面区域，在氮化COC层上形成粘合层，在粘合层上形成抗蚀剂，使抗蚀剂与形成图案的特征的印模模板接触 其中抗蚀剂填充压印模板的图案化特征，以及将印​​模模板与抗蚀剂分离，使得图案特征的负像形成在抗蚀剂中。 压印结构的实施例包括基板，形成在基板上的COC层，其中形成有氮化的上表面区域的COC层和形成在COC层上的粘合层，以及形成在粘合层上的抗蚀剂。