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    Small diameter endoscopic instruments
    1.
    发明授权
    Small diameter endoscopic instruments 失效
    小直径内窥镜仪器

    公开(公告)号：US5697949A

    公开(公告)日：1997-12-16

    申请号：US443466

    申请日：1995-05-18

    申请人： Joel F. Giurtino ,  George Nunez

    发明人： Joel F. Giurtino ,  George Nunez

    IPC分类号： A61B18/12 ,  A61B17/28 ,  A61B18/14 ,  A61B17/36

    CPC分类号： A61B18/1445 ,  A61B2017/2934 ,  A61B2017/2939 ,  A61B2018/00083 ,  A61B2018/126

    摘要： An endoscopic instrument includes a small diameter hollow tube, an axially displaceable wire extending through the tube, a manual actuator coupled to the proximal ends of the tube and wire for axially displacing the wire relative to the tube, a first end effector mechanically coupled to the distal end of the tube and having a proximal portion which is provided with a curved guiding channel which receives and guides a distal portion of the wire, and a second end effector mechanically coupled to the distal end of the displaceable wire and rotatably coupled to the first end effector. When arranged as a bipolar instrument, the tube and pull wire are conductive, the pull wire is covered with an electrically insulating sheath except at its very distal end, the first end effector is conductive and partially insulated and is electrically coupled to distal end of tube, and the second end effector is conductive and partially insulated and electrically coupled to the distal end of the pull wire. Both end effectors are preferably cast alloy partially coated with PTFE, and are rotatably coupled to each other with the aid of an insulating ceramic bushing-washer. According to one embodiment, the first end effector is provided with an integral axle pin. The provided endoscopic instrument, when the tube is 1.7 mm in diameter, is particularly useful in endoscopic neurological procedures.

    摘要翻译： 内窥镜仪器包括小直径中空管，延伸穿过管的可轴向移位的线，耦合到管的近端的手动致动器和用于使线相对于管轴向移位的线，第一端部执行器，机械地耦合到 管的远端并且具有近侧部分，该近端部分设置有弯曲的引导通道，该引导通道接收并引导线的远端部分，以及第二端部执行器，其机械地联接到可移位线的远端并且可旋转地联接到第一 末端执行器。 当布置为双极仪器时，管和拉线是导电的，拉线被绝缘护套覆盖，除了其非常远端，第一端部执行器是导电的并且部分绝缘并且电耦合到管的远端 ，并且第二端部执行器是导电的并且部分绝缘并且电耦合到拉线的远端。 两个末端执行器优选地部分涂覆有PTFE的铸造合金，并且借助于绝缘陶瓷衬套垫圈可旋转地彼此联接。 根据一个实施例，第一端部执行器设置有一体的轴销。 所提供的内窥镜器械，当管子直径为1.7mm时，在内窥镜神经学程序中特别有用。

    Apparatus for counting the number of times a medical instrument has been used
    2.
    发明授权
    Apparatus for counting the number of times a medical instrument has been used 失效
    用于计数医疗器械使用次数的装置

    公开(公告)号：US5359993A

    公开(公告)日：1994-11-01

    申请号：US998951

    申请日：1992-12-31

    申请人： Charles R. Slater ,  Thomas O. Bales ,  Jurgen A. Kortenbach ,  George Nunez ,  David Turkel

    发明人： Charles R. Slater ,  Thomas O. Bales ,  Jurgen A. Kortenbach ,  George Nunez ,  David Turkel

    IPC分类号： A61B1/00 ,  A61B17/00 ,  A61B17/28 ,  A61B19/00 ,  G06M1/04 ,  G06M1/08 ,  G06M3/12 ,  G01K5/00

    CPC分类号： A61B1/00062 ,  A61B17/00234 ,  G06M1/041 ,  G06M1/083 ,  G06M3/12 ,  A61B1/00055 ,  A61B2017/0046 ,  A61B2017/292 ,  A61B2090/0803 ,  A61B2560/0276

    摘要： An apparatus for counting the number of times a medical instrument has been sterilized includes an indicator having sequential indicia and a heat responsive member for indicating a next one of the indicia. Mechanical, fluid mechanical and electronic versions of the invention are disclosed. In the mechanical version, the indicator can be a ratchet member having teeth, a pawl and a display surface containing indicia. A heat responsive element such as a bimetallic member engages the teeth of the ratchet and advances the ratchet each time the apparatus is subjected to the heat of sterilization. A housing with a window masks the display to indicate one of the indicia as advanced by the heat responsive element. Preferred embodiments of the mechanical version include a ring-like ratchet member with interior teeth and an exterior display surface. The number of teeth is preferably one or more less than the number of indicia so that upon advancing the ratchet member to the last indicia, it can be advanced no further. The bimetallic element is mounted inside the ring and the housing covers the outer surface of the ring. The housing may be formed from the ferrule of an endoscopic surgical instrument or may be formed as part of the handle of such an instrument. A removable locking pin is provided to prevent movement of the ratchet member during shipping and the locking pin may be coupled to packaging so that it is automatically removed when the surgical instrument is removed from its packaging.

    摘要翻译： 用于计数医疗器械已经消毒的次数的装置包括具有顺序标记的指示器和用于指示下一个标记的热响应构件。 公开了本发明的机械，流体机械和电子版本。 在机械版本中，指示器可以是具有齿，棘爪和包含标记的显示表面的棘轮构件。 诸如双金属构件的热响应元件与棘轮的齿接合，并且每当设备经受灭菌热时每次使棘轮前进。 具有窗口的壳体遮蔽显示器，以指示由热响应元件提前的一个标记。 机械版本的优选实施例包括具有内齿和外部显示表面的环形棘轮构件。 优选地，齿数比标记的数量少一个或多个，从而在将棘轮构件推进到最后的标记之后，可以进一步推进。 双金属元件安装在环内，壳体覆盖环的外表面。 壳体可以由内窥镜手术器械的套圈形成，或者可以形成为这种器械的手柄的一部分。 提供可拆卸的锁定销以防止棘轮构件在运输期间的移动，并且锁定销可以联接到包装，使得当手术器械从其包装中移除时它被自动移除。

    Method and device for full thickness resectioning of an organ
    3.
    发明申请
    Method and device for full thickness resectioning of an organ 有权
    器官全面切除的方法和装置

    公开(公告)号：US20060191975A1

    公开(公告)日：2006-08-31

    申请号：US11411389

    申请日：2006-04-25

    申请人： Ronald Adams ,  Roy Sullivan ,  George Nunez ,  Lauren Main ,  Peter Kratsch ,  Jurgen Kortenbach ,  Matt Solar ,  Gerhard Buess ,  Marc Schurr

    发明人： Ronald Adams ,  Roy Sullivan ,  George Nunez ,  Lauren Main ,  Peter Kratsch ,  Jurgen Kortenbach ,  Matt Solar ,  Gerhard Buess ,  Marc Schurr

    IPC分类号： A61B17/04 ,  A61B17/08

    CPC分类号： A61B17/072 ,  A61B1/00087 ,  A61B17/07207 ,  A61B17/29 ,  A61B17/295 ,  A61B2017/00353 ,  A61B2017/07214 ,  A61B2017/07221 ,  A61B2017/2905 ,  A61B2017/2927 ,  A61B2090/038 ,  A61B2090/306

    摘要： Describeed is a full-thickness resection system which includes a control unit coupled to a proximal end of a flexible endoscope. The control unit remains outside of a body when the stapling head is in an operative position within a body lumen. The control unit includes (i) an anvil actuator coupled to an anvil in the stapling head, actuation of the anvil actuator moves the anvil axially relative to a stapling mechanism in the stapling head to compress a folded full-thickness portion of lumenal tissue between the anvil and the stapling mechanism. In addition, the control unit includes (ii) a stapler actuator coupled to the stapling mechanism in the stapling head, actuation of the stapler actuator causing the stapling mechanism to drive staples through the folded lumenal tissue against the anvil. Also, the control unit includes (iii) a tissue cutter actuator coupled to a tissue cutter in the stapling head, actuation of the tissue cutter actuator causing the tissue cutter to resect portions of the folded lumenal tissue.

    摘要翻译： 描述是全厚度切除系统，其包括耦合到柔性内窥镜的近端的控制单元。 当装订头处于体腔内的操作位置时，控制单元保持在身体外部。 控制单元包括（i）联接到装订头中的砧座的砧座致动器，砧座致动器相对于缝合头中的缝合机构轴向地轴向移动砧座，以压缩位于缝合头之间的管腔组织的折叠全部厚度部分 砧座和装订机构。 此外，控制单元包括（ii）联接到装订头中的装订机构的订书机致动器，致动订书机致动器，使订书机构将钉子穿过折叠的腔组织抵靠砧座。 此外，控制单元包括（iii）联接到装订头中的组织切割器的组织切割器致动器，促使组织切割器致动器致使组织切割器切除折叠的腔组织的部分。

    Hydrophilic coating and substrates coated therewith having enhanced durablity and lubricity
    4.
    发明授权
    Hydrophilic coating and substrates coated therewith having enhanced durablity and lubricity 失效
    亲水涂层和涂覆的基材具有增强的耐久性和润滑性

    公开(公告)号：US06709706B2

    公开(公告)日：2004-03-23

    申请号：US10387380

    申请日：2003-03-14

    申请人： Shengping Zhong ,  George Nunez ,  Eric Welch

    发明人： Shengping Zhong ,  George Nunez ,  Eric Welch

    IPC分类号： B05D304

    CPC分类号： A61L29/14 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/452 ,  A61L2300/608 ,  A61L2400/10 ,  C08J7/042 ,  C08J2367/00 ,  C08J2433/26 ,  C08J2475/06 ,  C09D133/24 ,  C09D175/06 ,  C09D175/08 ,  Y10T428/1393 ,  Y10T428/24793 ,  Y10T428/24802 ,  Y10T428/31536 ,  Y10T428/31576 ,  C08L75/04

    摘要： A substrate, such as a catheter or a guide wire, or a portion of the substrate is provided with a lubricous, hydrophilic abrasion-resistant coating by: (a) coating the substrate with a first aqueous coating composition having an aqueous dispersion or emulsion of a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups capable of reacting with organic acid groups, and drying the coating to obtain a substantially water-insoluble coating layer having excess polyfunctional including functional groups being reactive with organic acid groups remaining; and (b) contacting the dried water-insoluble coating layer with a second aqueous coating composition having an aqueous solution or dispersion of a hydrophilic polymer having organic acid functional groups, a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups capable of reacting with organic acid groups, and drying the combined coating to form an intermediate coating, whereby the polymer and the hydrophilic polymer of the second composition become bonded to the polymer of the first coating composition through the excess crosslinking agent; and (c) contacting the dried intermediate coating with a third aqueous coating composition having an aqueous solution or dispersion of a hydrophilic polymer having organic acid functional groups, and drying the combined coatings, the hydrophilic polymer of the third coating composition thereby becoming bonded to the polymers of the second coating composition through the excess crosslinking agent. The dryings can be carried out at ambient (room) temperature.

    摘要翻译： 通过以下方法，将基材（例如导管或引导线）或基底的一部分设置有润滑的亲水性耐磨涂层：（a）用第一水性涂料组合物涂覆基材，所述第一水性涂料组合物具有水分散体或乳液 具有有机酸官能团的聚合物和具有能够与有机酸基反应的官能团的多官能交联剂，并干燥该涂层以获得具有过剩多官能团的基本上不溶于水的涂层，所述多官能团包含与剩余的有机酸基团反应的官能团; 和（b）使干燥的水不溶性涂层与具有具有有机酸官能团的亲水性聚合物的水溶液或分散体的第二水性涂料组合物接触，具有有机酸官能团的聚合物和具有官能团的多官能交联剂 与有机酸基团反应，并干燥组合的涂层以形成中间涂层，由此第二组合物的聚合物和亲水性聚合物通过过量交联剂与第一涂料组合物的聚合物结合; 和（c）使干燥的中间涂层与具有具有有机酸官能团的亲水聚合物的水溶液或分散体的第三水性涂料组合物接触，并干燥组合的涂层，由此将第三涂料组合物的亲水性聚合物粘合到 第二涂料组合物通过过量交联剂的聚合物。 干燥可在室温下进行。

    Apparatus for counting the number of times a surgical instrument has been used
    5.
    发明授权
    Apparatus for counting the number of times a surgical instrument has been used 失效
    用于计数外科器械已使用次数的装置

    公开(公告)号：US5313935A

    公开(公告)日：1994-05-24

    申请号：US107456

    申请日：1993-08-17

    申请人： Jurgen A. Kortenbach ,  George Nunez ,  Charles R. Slater

    发明人： Jurgen A. Kortenbach ,  George Nunez ,  Charles R. Slater

    IPC分类号： A61B1/00 ,  A61B17/00 ,  A61B17/28 ,  A61B18/14 ,  A61B19/00 ,  G06M1/04 ,  G06M3/12

    CPC分类号： A61B1/00062 ,  A61B1/00105 ,  A61B17/00234 ,  G06M1/041 ,  G06M3/12 ,  A61B1/00055 ,  A61B18/14 ,  A61B2017/0046 ,  A61B2017/292 ,  A61B2018/00178 ,  A61B2018/1412 ,  A61B2018/1415 ,  A61B2018/1455 ,  A61B2018/1861 ,  A61B2090/0803 ,  A61B2560/0276

    摘要： An improved use counter for endoscopic instruments is mounted in the ferrule of the distal portion of an endoscopic instrument having separable proximal and distal portions. The counter includes a ratchet wheel having inner and outer teeth and a bimetallic coil having a fixed end and a free end. The fixed end of the bimetallic coil is attached to a hub portion of the ferrule and the free end of the bimetallic coil engages the inner teeth of the ratchet wheel. An inwardly extending tooth in the ferrule engages the outer teeth of the ratchet wheel to prevent backward movement of the ratchet wheel. The outer surface of the ratchet wheel is also provided with incremental indicia viewable through a window in the ferrule. As the bimetallic coil is heated and cooled when the instrument is sterilized, the free end of the coil engages and advances one tooth of the ratchet wheel. Movement of the free end is preferably limited by stops. A spring biased locking and disabling pin is mounted in the ferrule and engages a stepped width portion of the ratchet wheel. The pin prevents advancement of the ratchet wheel during shipping and disables the instrument after a predetermined number of sterilizations.

    摘要翻译： 用于内窥镜器械的改进的使用计数器安装在具有可分离的近端部分和远端部分的内窥镜器械的远端部分的套圈中。 计数器包括具有内齿和外齿的棘轮和具有固定端和自由端的双金属线圈。 双金属线圈的固定端附接到套圈的毂部，双金属线圈的自由端与棘轮的内齿啮合。 套圈内的向内延伸的齿接合棘轮的外齿，以防止棘轮向后移动。 棘轮的外表面还具有通过套圈中的窗口可见的增量标记。 当双金属线圈在仪器灭菌时被加热和冷却，线圈的自由端接合并前进棘轮的一个齿。 自由端的移动优选地通过停止来限制。 弹簧偏置的锁定和禁用销安装在套圈中并与棘轮的台阶宽度部分接合。 销钉防止在运输过程中棘轮的前进，并在预定数量的灭菌之后禁用该仪器。

    Endoscopic instruments having low friction sheath
    7.
    发明授权
    Endoscopic instruments having low friction sheath 失效
    内窥镜仪器具有低摩擦护套

    公开(公告)号：US5591202A

    公开(公告)日：1997-01-07

    申请号：US234641

    申请日：1994-04-28

    申请人： Charles R. Slater ,  Kevin W. Smith ,  Matthew A. Palmer ,  Anthony I. Mazzeo ,  George Nunez

    发明人： Charles R. Slater ,  Kevin W. Smith ,  Matthew A. Palmer ,  Anthony I. Mazzeo ,  George Nunez

    IPC分类号： A61B17/00 ,  A61B17/28 ,  A61B10/00

    CPC分类号： A61B17/29 ,  A61B2017/0084

    摘要： A low friction sheath for endoscopic instruments is made from an extrusion grade of high density polyethylene (HDPE). The sheath is formed as an extruded polyethylene tube having an inner diameter slightly smaller than the outer diameter of the instrument it will cover. In order to place the sheath over the instrument, a containment sleeve is placed over the sheath and a source of pressurized gas is coupled to one end of the sheath. The endoscopic instrument tube is sealed and inserted into the other end of the sheath. The polyethylene sheath is filled with gas so that it expands against the containment sleeve and the endoscopic instrument tube is pushed into the expanded polyethylene sheath. The gas is released from the polyethylene sheath and it contracts against the outer surface of the endoscopic instrument tube. The sheath is preferably made from a HDPE having a microfractured surface with 10-20 micron fractures.

    摘要翻译： 用于内窥镜器械的低摩擦护套由挤出级别的高密度聚乙烯（HDPE）制成。 护套形成为挤出的聚乙烯管，其内径略小于其将覆盖的器械的外径。 为了将护套放置在仪器上方，将容纳套筒放置在护套上方，并且加压气体源联接到护套的一端。 内窥镜器械管被密封并插入护套的另一端。 聚乙烯护套充满气体，使其膨胀抵靠容纳套筒，内窥镜器械管被推入膨胀聚乙烯护套。 气体从聚乙烯护套中释放出来并与内窥镜器械管的外表面收缩。 护套优选由具有10-20微米骨折的微裂纹表面的HDPE制成。

    Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity
    9.
    发明授权
    Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity 有权

    公开(公告)号：US06558798B2

    公开(公告)日：2003-05-06

    申请号：US09876556

    申请日：2001-06-07

    申请人： Shengping Zhong ,  George Nunez ,  Eric Welch

    发明人： Shengping Zhong ,  George Nunez ,  Eric Welch

    IPC分类号： B32B704

    CPC分类号： A61L29/14 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/452 ,  A61L2300/608 ,  A61L2400/10 ,  C08J7/042 ,  C08J2367/00 ,  C08J2433/26 ,  C08J2475/06 ,  C09D133/24 ,  C09D175/06 ,  C09D175/08 ,  Y10T428/1393 ,  Y10T428/24793 ,  Y10T428/24802 ,  Y10T428/31536 ,  Y10T428/31576 ,  C08L75/04

    摘要： A substrate, such as a catheter or a guide wire, or a portion of the substrate is provided with a lubricous, hydrophilic abrasion-resistant coating by: (a) coating the substrate with a first aqueous coating composition having an aqueous dispersion or emulsion of a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups capable of reacting with organic acid groups, and drying the coating to obtain a substantially water-insoluble coating layer having excess polyfunctional including functional groups being reactive with organic acid groups remaining; and (b) contacting the dried water-insoluble coating layer with a second aqueous coating composition having an aqueous solution or dispersion of a hydrophilic polymer having organic acid functional groups, a polymer having organic acid functional groups and a polyfunctional crosslinking agent having functional groups capable of reacting with organic acid groups, and drying the combined coating to form an intermediate coating, whereby the polymer and the hydrophilic polymer of the second composition become bonded to the polymer of the first coating composition through the excess crosslinking agent; and (c) contacting the dried intermediate coating with a third aqueous coating composition having an aqueous solution or dispersion of a hydrophilic polymer having organic acid functional groups, and drying the combined coatings, the hydrophilic polymer of the third coating composition thereby becoming bonded to the polymers of the second coating composition through the excess crosslinking agent. The dryings can be carried out at ambient (room) temperature.