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公开(公告)号：US4745077A
公开(公告)日：1988-05-17
申请号：US692162
申请日：1985-01-17
IPC分类号： A61K39/00 , G01N33/543 , G01N33/553 , G01N33/533
CPC分类号： G01N33/54333 , Y10S436/80 , Y10S436/809
摘要： The invention concerns assays, such a immunoassays or two-site immunometric assays, performed using a labelled reagent and another reagent bound to magnetically attractable particles which are suspendable but insoluble in a liquid assay medium. After the labelled reagent has become partitioned between the liquid phase and the particles, in proportions which depend on the concentration of an analyte in a sample, the liquid phase is removed. Then the particles are re-suspended in another liquid medium, and the concentration of label observed. The method is particularly suitable for fluorescent and chemiluminescent' label systems, and can conveniently be performed in microtiter plates in which the wells are optically screened from one another, the observations being made from above or below the wells.
摘要翻译： 本发明涉及使用标记的试剂和结合到可悬浮但不溶于液体测定培养基的磁性可吸引颗粒的另一试剂进行的测定，如免疫测定或双位点免疫测定。 在标记试剂在液相和颗粒之间分配后，以取决于样品中分析物浓度的比例，液相被除去。 然后将颗粒重新悬浮在另一种液体介质中，并观察标签的浓度。 该方法特别适用于荧光和化学发光的标记系统，并且可以方便地在微孔板中进行，其中孔彼此光学屏蔽，观察是从孔的上方或下方进行的。
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公开(公告)号：US4666863A
公开(公告)日：1987-05-19
申请号：US582591
申请日：1984-02-22
IPC分类号： G01N30/95 , G01N33/538 , G01N33/543 , G01N33/558 , G01N33/74 , G01N33/536 , G01N33/78
CPC分类号： G01N33/54313 , G01N33/538 , G01N33/558 , G01N33/74
摘要： A method of performing an assay for an analyte comprises providing a chromatographic medium, preferably in sheet form, forming a reaction mixture containing a labelled reagent present partly in a form which is mobile on the medium and partly in a form which is immobile, the proportions of the two forms being related to the analyte concentration, applying the mixture to a spot on the chromatographic medium, optionally applying a solvent to cause the mobile form of the labelled reagent to migrate from the spot, and measuring the label intensity remaining at the spot. The method provides a convenient way of performing immunoassays, 2-site immunometric assays, and agglutination assays.
摘要翻译： 对分析物进行测定的方法包括提供优选片状形式的色谱介质，形成含有标记试剂的反应混合物，所述反应混合物部分存在于介质上可移动的部分形式，部分以不动的形式存在， 的两种形式与分析物浓度相关，将混合物施加到色谱介质上的点上，任选地施加溶剂以使得标记试剂的可移动形式从斑点迁移，并测量残留在斑点处的标记强度 。 该方法提供了进行免疫测定，2位点免疫测定和凝集测定的便利方式。
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公开(公告)号：USD340084S
公开(公告)日：1993-10-05
申请号：US691105
申请日：1991-04-25
申请人： John K. Martin
设计人： John K. Martin
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公开(公告)号：US4200449A
公开(公告)日：1980-04-29
申请号：US898080
申请日：1978-04-20
申请人： John K. Martin
发明人： John K. Martin
IPC分类号： C03B7/16 , C03B9/193 , C03B9/195 , C03B9/295 , C03B9/353 , C03B9/36 , C03B9/38 , C03B9/40 , C03B9/00 , C03B9/14
CPC分类号： C03B9/3681 , C03B7/16 , C03B9/1932 , C03B9/1934 , C03B9/1936 , C03B9/195 , C03B9/1955 , C03B9/295 , C03B9/353 , C03B9/3532 , C03B9/3618 , C03B9/3627 , C03B9/3636 , C03B9/3645 , C03B9/3808 , C03B9/3816 , C03B9/3858 , C03B9/3875 , C03B9/3891 , C03B9/40
摘要： A multi-section blow molding machine for the manufacture of hollow glassware has in each section a parison mold for each pair of blow molds. The blow molds are disposed below and on opposite sides of the center of oscillation of a neck ring arm carrying rotatable neck rings and arranged so that the mold or molds on one side are open when those on the other side are closed. The molds and neck ring arm are interconnected to oscillate together in opposite directions between lockable positions 180.degree. apart. The parison mold and associated feed and plunger means are movable in and out of operative position below and above the neck ring arm respectively, and operate in timed relation thereto. The open blow molds are spray cooled during the blowing cycle as well as during oscillation of the neck ring arm between its locked positions. In the closed blow molds, the blowing is continued simultaneously with the spray cooling to further cool the molded articles prior to release to a take-out conveyor.
摘要翻译： 用于制造中空玻璃器皿的多段吹塑机在每个部分中具有用于每对吹塑模具的型坯模具。 吹塑模具设置在承载可旋转颈环的颈环臂的振荡中心的下方和相对侧上，并且布置成使得当另一侧的模具或模具被关闭时，一侧的模具或模具是敞开的。 模具和颈环臂相互连接，以相隔180°的可锁定位置之间相反的方向摆动。 型坯模具和相关联的进料和柱塞装置分别在颈环臂下方和上方的操作位置移动和移动，并以与其成正比的关系操作。 吹塑模具在吹塑循环期间以及在颈环臂在其锁定位置之间振荡期间被喷雾冷却。 在封闭式吹塑模具中，喷雾在喷雾冷却的同时继续进行，以便在释放到取出输送机之前进一步冷却模制品。
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公开(公告)号：US06415988B1
公开(公告)日：2002-07-09
申请号：US09577206
申请日：2000-05-23
申请人： John K. Martin
发明人： John K. Martin
IPC分类号： E01B2600
CPC分类号： E01B9/62 , E01B9/60 , E01B19/00 , E01B2204/11
摘要： A rail track insert assembly for use in road-level railway crossings having a pair of rails secured to a rail bed, each of the rails having a gauge side and a field side, a rail base and an intermediate web and being adapted for limited vertical movement upon intermittent loading of the rail upon passage of a load on the rail, the assembly comprising a longitudinally extending flexible gauge side rail insert member having a top surface in the plane of the rail head and a bottom surface registering with the base of the rail, a rail-engaging side surface sealingly and fixedly registering with the web on the gauge side in order to move with the limited movement of the rail, and an opposite side surface including a planar surface inclined downwardly and outwardly away from the adjacent rail at a minor angle, a longitudinally extending center gauge panel comprising a rigid slab having a top planar road surface lying in the general plane of the top surfaces of the rails, a bottom surface engaging with the tie bed, and side surfaces including an inclined planar surface registering in tight compressive contact with the inclined planar surfaces of each of the first rail insert members when the rails are in unloaded condition and to register in looser compressive contact with each of the inclined planar surfaces of the insert member when the rail is in loaded condition.
摘要翻译： 一种用于道路级铁路路口的轨道插入组件，其具有固定到轨道床的一对轨道，每个轨道具有测量侧和场侧，轨道基座和中间腹板，并且适于有限垂直 所述组件包括纵向延伸的挠性量规侧轨道插入件，该导轨插入件在轨道头的平面内具有顶表面，底表面与轨道的底座对准 轨道接合侧表面密封地且固定地与测量仪侧上的腹板对准，以便随着轨道的有限运动而移动;以及相对的侧表面，其包括在一个相对的轨道上向下和向外远离相邻轨道的平面 小角度，纵向延伸的中心计量板，其包括刚性板，其具有位于轨道的顶表面的总平面中的顶部平面路面，底面表面 并且当所述轨道处于卸载状态时，包括倾斜的平坦表面的侧表面与所述第一轨道插入件中的每一个的倾斜的平坦表面配准紧密地压接， 当轨道处于加载状态时，插入构件的倾斜平面。
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公开(公告)号：US5039494A
公开(公告)日：1991-08-13
申请号：US458455
申请日：1990-01-29
申请人： Juan N. Martin , John K. Martin
发明人： Juan N. Martin , John K. Martin
CPC分类号： B01D50/00 , A61M1/0054 , B01D49/00 , A61B2218/008
摘要： In order to render harmless the aerosol laden smoke stream which results from the operation of medical lasers in or on mammalian bodies, the stream is moved in a closed circuit maintained at negative pressure. The circuit includes a container of sterilizing fluid to retain and destroy the larger aerosol particles and downstream of that container a chamber having an oxygen enriched atmosphere which is heated to a temperature sufficient to incinerate the remaining aerosol particles which are too small to filter. The thus purified stream is then cooled and released to ambient.
摘要翻译： 为了使由哺乳动物体内或哺乳动物体内的医用激光器的操作产生的气溶胶载气烟雾无害化，流体在保持负压的闭路中移动。 电路包括一个消毒流体的容器，用于保持和破坏较大的气溶胶颗粒，并且在该容器的下游有一个具有富氧气氛的室，该腔室被加热至足以焚化剩余气溶胶颗粒的温度，这些气溶胶颗粒太小而不能过滤。 然后将如此纯化的物流冷却并释放至环境温度。
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公开(公告)号：US4921679A
公开(公告)日：1990-05-01
申请号：US313013
申请日：1989-02-21
申请人： Juan N. Martin , John K. Martin
发明人： Juan N. Martin , John K. Martin
CPC分类号： B01D50/00 , A61M1/0054 , B01D49/00 , A61B2218/008
摘要： In order to render harmless the aerosol laden smoke stream which results from the operation of medical lasers in or on mammalian bodies, the stream is moved in a closed circuit maintained at negative pressure. The circuit includes a container of sterilizing fluid to retain and destroy the larger aerosol particles and downstream of that container a chamber having an oxygen enriched atmosphere which is heated to a temperature sufficient to incinerate the remaining aerosol particles which are too small to filter. The thus purified stream is then cooled and released to ambient.
摘要翻译： 为了使由哺乳动物体内或哺乳动物体内的医用激光器的操作产生的气溶胶载气烟雾无害化，流体在保持负压的闭路中移动。 电路包括一个消毒流体的容器，用于保持和破坏较大的气溶胶颗粒，并且在该容器的下游有一个具有富氧气氛的室，该腔室被加热至足以焚化剩余气溶胶颗粒的温度，这些气溶胶颗粒太小而不能过滤。 然后将如此纯化的物流冷却并释放至环境温度。
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公开(公告)号：US5622312A
公开(公告)日：1997-04-22
申请号：US534235
申请日：1995-09-26
申请人： John K. Martin
发明人： John K. Martin
CPC分类号： E01B9/60 , E01B19/00 , E01B9/62 , E01B2204/11
摘要： Rail track insert assembly for use between rails and adjacent road surfaces in a road level rail bed comprising resiliently flexible elongate members engaging, respectively, with the rail and the adjacent road surface and defining a generally vertical slip plane at their interface, to accommodate vertical movement of the rail in response to the passage of rail car wheels, while sealing against intrusion of surface water and detritus. An elongated channel defined in the under surface of each of the insert members accommodates rail clips securing the rail to the underlying track bed.
摘要翻译： 轨道轨道插入组件，用于轨道和道路平面轨道床中的相邻路面之间的轨道插入组件，其包括分别与轨道和相邻道路表面接合的弹性柔性细长构件，并在其界面处限定大致垂直的滑动平面，以适应垂直运动 的轨道，以响应轨道车轮的通过，同时密封地表水和碎屑的侵入。 限定在每个插入构件的下表面中的细长通道容纳将轨道固定到下面的轨道床的轨道夹具。
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公开(公告)号：US4284424A
公开(公告)日：1981-08-18
申请号：US99545
申请日：1979-12-03
申请人： John K. Martin
发明人： John K. Martin
CPC分类号： C03B9/1936 , C03B9/1932 , C03B9/1934 , C03B9/1955 , C03B9/295 , C03B9/342 , C03B9/353 , C03B9/3532 , C03B9/3618 , C03B9/3627 , C03B9/3636 , C03B9/3645 , C03B9/3672
摘要： A rotatable neck ring assembly for use primarily in an automatic blow molding machine includes an annular bushing and a concentrically arranged series of pivotally mounted foot members which in their closed position cooperate with the bushing to hold a parison during molding of the ware. The feet are spring-biased toward open position and cammed in to closed position when engaged by the upwardly moving parison mold. Cam surfaces on the outer surface of the feet cooperate with corresponding surfaces on a concentrically surrounding sleeve to hold the ring tightly closed on the rim of the parison even after lowering of the parison mold and throughout the blow molding portion of the cycle. The ring is opened following the molding and cooling portions of the cycle by hydraulic pressure acting on a piston which engages the upper surface of the bushing to force the feet to pivot outwardly.
摘要翻译： 主要用于自动吹瓶机的可旋转颈环组件包括环形衬套和同轴布置的一系列可枢转地安装的脚部件，其在其关闭位置与衬套配合以在器具成型期间保持型坯。 当被向上移动的型坯模具接合时，脚被弹簧偏压到打开位置并且被固定到关闭位置。 在脚的外表面上的凸轮表面与同心围绕的套筒上的相应表面配合，以便即使在型坯模具和整个吹塑成型部分的下降之后，也将密封圈紧紧地保持在型坯的边缘上。 在循环的模制和冷却部分之后，通过作用在与衬套的上表面接合的活塞上的液压来打开环，以迫使脚部向外枢转。
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公开(公告)号：US3941371A
公开(公告)日：1976-03-02
申请号：US560375
申请日：1975-03-20
申请人： John K. Martin
发明人： John K. Martin
CPC分类号： B65H29/32 , Y10S414/113
摘要： A plurality of transfer conveyors are arranged at right angles to and spaced along a main conveyor for transferring selected sheets from said main conveyor and either dropping them in a reject bin or stacking them in separate piles depending upon the size of the sheets. The transfer conveyors overlie the main conveyor and operate to pick up sheets from the main conveyor by Bernoulli's principle and permit them to slide by gravity to the reject bin while supported in non-contacting relation by the nozzles. The nozzles are selectively actuated in groups to achieve the pickup and reject functions. Sheets not rejected leave the lower end of the transfer conveyor and fly free to the stack receiver which is positioned in line with the conveyor and spaced outwardly therefrom.
摘要翻译： 多个转印输送机被布置成与主输送机成直角并间隔开，用于从所述主输送机输送选定的纸张，并将它们丢弃在废料箱中，或者根据纸张的尺寸将它们堆叠在单独的堆中。 转运输送机位于主输送机上方，并通过伯努利的原理操作从主输送机上取纸，并允许它们通过重力滑动到废料箱，同时通过喷嘴以非接触的关系支撑。 喷嘴被选择性地分组地致动以实现拾取和拒收功能。 纸张不被拒绝离开传送输送机的下端，并自由飞行到与输送机成一直线并与其分开的堆叠接收器。
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