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    Optical imaging device
    1.
    发明授权
    Optical imaging device 有权
    光学成像装置

    公开(公告)号：US06615072B1

    公开(公告)日：2003-09-02

    申请号：US09315982

    申请日：1999-05-21

    申请人： Joseph A. Izatt ,  Michael V. Sivak ,  Andrew Rollins ,  Akihiro Horii ,  Tadashi Hirata ,  Shuhei Iizuka ,  Jiro Narita

    发明人： Joseph A. Izatt ,  Michael V. Sivak ,  Andrew Rollins ,  Akihiro Horii ,  Tadashi Hirata ,  Shuhei Iizuka ,  Jiro Narita

    IPC分类号： A61B600

    CPC分类号： A61B5/6852 ,  A61B5/0066 ,  G01B9/02002 ,  G01B9/0205 ,  G01B9/02061 ,  G01B9/02069 ,  G01B9/02091 ,  G01B2290/65 ,  G01B2290/70

    摘要： An Optical Coherence Tomography (OCT) device irradiates a biological tissue with low coherence light, obtains a high resolution tomogram of the inside of the tissue by low-coherent interference with scattered light from the tissue, and is provided with an optical probe which includes an optical fiber having a flexible and thin insertion part for introducing the low coherent light. When the optical probe is inserted into a blood vessel or a patient's body cavity, the OCT enables the doctor to observe a high resolution tomogram. In a optical probe, generally, a fluctuation of a birefringence occurs depending on a bend of the optical fiber, and this an interference contrast varies depending on the condition of the insertion. The OCT of the present invention is provided with polarization compensation means such as a Faraday rotator on the side of the light emission of the optical probe, so that the OCT can obtain the stabilized interference output regardless of the state of the bend.

    摘要翻译： 光学相干断层扫描（OCT）装置以低相干光照射生物组织，通过与来自组织的散射光的低相干干涉获得组织内部的高分辨率断层图像，并且设置有包括 光纤具有用于引入低相干光的柔性和薄的插入部分。 当光学探针插入血管或患者的体腔时，OCT使医生能够观察高分辨率的断层图像。 在光学探针中，通常根据光纤的弯曲发生双折射的波动，并且这种干涉对比度根据插入的条件而变化。 本发明的OCT在光学探针的发光侧设置有诸如法拉第旋转器的偏振补偿装置，使得OCT可以获得稳定的干涉输出，而不管弯曲的状态如何。

    Optical imaging apparatus
    5.
    发明授权
    Optical imaging apparatus 有权
    光学成像装置

    公开(公告)号：US07180600B2

    公开(公告)日：2007-02-20

    申请号：US10874573

    申请日：2004-06-24

    申请人： Akihiro Horii ,  Hitoshi Ueno ,  Shuhei Iizuka ,  Hitoshi Mizuno ,  Tadashi Hirata

    发明人： Akihiro Horii ,  Hitoshi Ueno ,  Shuhei Iizuka ,  Hitoshi Mizuno ,  Tadashi Hirata

    IPC分类号： G01B9/02 ,  A61B6/00

    CPC分类号： A61B5/6852 ,  A61B5/0062 ,  A61B5/0066 ,  G01N21/4795

    摘要： An optical imaging apparatus has an optical scanning probe configured to irradiate low-coherence light onto a subject and to perform photo-reception of light scattered at the subject, and an observation device adapted to construct a cross-section image of the subject based on information from the light received through the optical scanning probe. The optical scanning probe is detachably connected to the observation device.

    摘要翻译： 光学成像装置具有：光学扫描探针，被配置为将低相干光照射到被摄体上并对被检体散射的光进行光接收;以及观察装置，其适于基于信息构建被检体的截面图像 从通过光学扫描探测器接收的光线。 光学扫描探针可拆卸地连接到观察装置。

    Optical probe for producing tomogram of specimen by the use of low-coherence light
    8.
    发明授权
    Optical probe for producing tomogram of specimen by the use of low-coherence light 失效

    公开(公告)号：US07029436B2

    公开(公告)日：2006-04-18

    申请号：US10095225

    申请日：2002-03-08

    申请人： Shuhei Iizuka ,  Akihiro Horii ,  Mamoru Kaneko ,  Kenji Hirooka ,  Hitoshi Mizuno

    发明人： Shuhei Iizuka ,  Akihiro Horii ,  Mamoru Kaneko ,  Kenji Hirooka ,  Hitoshi Mizuno

    IPC分类号： A61B1/00

    CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/0073

    摘要： On the side at hand of an optical probe, a whole rotation transfer connector rotates while being supported by a ball bearing and a slide bearing and, therefore, rotation is transferred to a flexible shaft. The relative position between the flexible shaft and an optical sheath is changed in accordance with the amount of screwing of a sheath stopping member on the side at hand into an outer cylinder by an external thread portion and an internal thread portion. When the optical sheath is moved furthermore, the flexible shaft is elongated due to elastic deformation because the length of the flexible shaft is regulated by the interval between a locking part of a locking member at the tip and a shaft stopping member. A tip housing is made to contact with the locking member while tension is applied to the flexible shaft by the rear end surface in the direction of the side at hand. During the use of optical probe, even when the optical probe is curved and the inner surface of the flexible shaft is contacted with the inner surface of the optical sheath, moving of the tip housing is canceled by the elongation amount of the flexible shaft elongated in advance and, therefore, the tip housing rotates at a constant position relative to the probe longitudinal direction on all occasions.

    Optical image pickup apparatus for imaging living body tissue
    9.
    发明授权
    Optical image pickup apparatus for imaging living body tissue 有权
    用于对活体组织进行成像的光学图像拾取装置

    公开(公告)号：US07129473B2

    公开(公告)日：2006-10-31

    申请号：US10846967

    申请日：2004-05-14

    申请人： Yasushige Ishihara ,  Atsushi Okawa ,  Hiroshi Tosaka ,  Tianyu Xie ,  Tadashi Hirata ,  Akihiro Horii ,  Kazunari Tokuda

    发明人： Yasushige Ishihara ,  Atsushi Okawa ,  Hiroshi Tosaka ,  Tianyu Xie ,  Tadashi Hirata ,  Akihiro Horii ,  Kazunari Tokuda

    IPC分类号： G01B5/28 ,  G02B26/08

    CPC分类号： A61B1/04 ,  A61B1/0008 ,  A61B1/00096 ,  A61B1/00165 ,  A61B1/00172 ,  A61B1/00183 ,  A61B1/00188 ,  A61B1/07 ,  G02B21/0032 ,  G02B21/0036

    摘要： A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.

    摘要翻译： 光学摄像装置的控制部分包括扫描驱动器，锁定放大器和A / D转换器。 扫描驱动器向Y扫描镜和X扫描镜输出预定的驱动信号，扫描Y扫描镜和X扫描镜。 锁定放大器在由检测器部分检测的信号中检测扫描驱动器的驱动信号的频率分量的信号电平Vout。 A / D转换器将由检测器部分检测的信号和由锁定放大器检测的驱动信号的频率分量的检测信号的信号电平转换为数字信号，并将数字信号输出到图像处理器。 因此，可以可靠地检测扫描镜的镜像扫描操作。

    Optical image pickup apparatus for imaging living body tissue
    10.
    发明授权
    Optical image pickup apparatus for imaging living body tissue 有权
    用于对活体组织进行成像的光学图像拾取装置

    公开(公告)号：US07427747B2

    公开(公告)日：2008-09-23

    申请号：US11494184

    申请日：2006-07-27

    申请人： Yasushige Ishihara ,  Atsushi Okawa ,  Hiroshi Tosaka ,  Tianyu Xie ,  Tadashi Hirata ,  Akihiro Horii ,  Kazunari Tokuda

    发明人： Yasushige Ishihara ,  Atsushi Okawa ,  Hiroshi Tosaka ,  Tianyu Xie ,  Tadashi Hirata ,  Akihiro Horii ,  Kazunari Tokuda

    IPC分类号： H01J3/14 ,  G01B11/30

    CPC分类号： A61B1/04 ,  A61B1/0008 ,  A61B1/00096 ,  A61B1/00165 ,  A61B1/00172 ,  A61B1/00183 ,  A61B1/00188 ,  A61B1/07 ,  G02B21/0032 ,  G02B21/0036

    摘要： A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.

    摘要翻译： 光学摄像装置的控制部分包括扫描驱动器，锁定放大器和A / D转换器。 扫描驱动器向Y扫描镜和X扫描镜输出预定的驱动信号，扫描Y扫描镜和X扫描镜。 锁定放大器在由检测器部分检测的信号中检测扫描驱动器的驱动信号的频率分量的信号电平Vout。 A / D转换器将由检测器部分检测的信号和由锁定放大器检测的驱动信号的频率分量的检测信号的信号电平转换为数字信号，并将数字信号输出到图像处理器。 因此，可以可靠地检测扫描镜的镜像扫描操作。