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190 条记录 (耗时 0.045 秒)

    Amino alcohol derivatives, medicinal composition containing the same, and use of these
    5.
    发明授权
    Amino alcohol derivatives, medicinal composition containing the same, and use of these 失效
    氨基醇衍生物，含有该组合物的药用组合物及其用途

    公开(公告)号：US07417169B2

    公开(公告)日：2008-08-26

    申请号：US10576753

    申请日：2004-10-05

    申请人： Junichi Kobayashi ,  Tetsuya Nakamura ,  Hideyuki Muranaka ,  Takehiro Ishikawa ,  Tetsuro Tamai ,  Satoshi Akahane

    发明人： Junichi Kobayashi ,  Tetsuya Nakamura ,  Hideyuki Muranaka ,  Takehiro Ishikawa ,  Tetsuro Tamai ,  Satoshi Akahane

    IPC分类号： C07C211/00 ,  C07C311/00 ,  A61K31/18 ,  A61K31/135

    CPC分类号： C07D235/24 ,  C07C233/43 ,  C07C311/21

    摘要： The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is —COR10, -A1-COR10, —O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, —OCH2—, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.

    摘要翻译： 本发明提供由通式（I）表示的化合物：其前药或其药学上可接受的盐，其中R 1是氢或低级烷基; R2和R3各自独立地为氢或低级烷基; R 4，R 5和R 6各自独立地是氢，卤素，低级烷基或低级烷氧基; R 7是氢或低级烷基; R 8是氢，卤素，低级烷基，低级烷氧基等; R 9是-COR 10，-A 1 -OR 10，-OA 2， SUP> -COR 10等; Ar是任选取代的苯基或杂芳基; 并且A是表现出有效和选择性的β3肾上腺素受体刺激活性的键-OCH 2 - 2等。 本发明还提供含有所述化合物的药物组合物及其用途。

    Amino alcohol derivatives, medicinal composition containing the same, and use of these
    6.
    发明申请
    Amino alcohol derivatives, medicinal composition containing the same, and use of these 失效
    氨基醇衍生物，含有该组合物的药用组合物及其用途

    公开(公告)号：US20070078184A1

    公开(公告)日：2007-04-05

    申请号：US10576753

    申请日：2004-10-05

    申请人： Junichi Kobayashi ,  Tetsuya Nakamura ,  Hideyuki Muranaka ,  Takehiro Ishikawa ,  Tetsuro Tamai ,  Satoshi Akahane

    发明人： Junichi Kobayashi ,  Tetsuya Nakamura ,  Hideyuki Muranaka ,  Takehiro Ishikawa ,  Tetsuro Tamai ,  Satoshi Akahane

    IPC分类号： A61K31/195 ,  C07C309/50

    CPC分类号： C07D235/24 ,  C07C233/43 ,  C07C311/21

    摘要： The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is —COR10, -A1-COR10, —O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, —OCH2—, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.

    摘要翻译： 本发明提供由通式（I）表示的化合物：其前药或其药学上可接受的盐，其中R 1是氢或低级烷基; R2和R3各自独立地为氢或低级烷基; R 4，R 5和R 6各自独立地是氢，卤素，低级烷基或低级烷氧基; R 7是氢或低级烷基; R 8是氢，卤素，低级烷基，低级烷氧基等; R 9是-COR 10，-A 1 -OR 10，-OA 2， SUP> -COR 10等; Ar是任选取代的苯基或杂芳基; 并且A是表现出有效和选择性的β3肾上腺素受体刺激活性的键-OCH 2 - 2等。 本发明还提供含有所述化合物的药物组合物及其用途。

    Push switch
    9.
    发明授权
    Push switch 有权

    公开(公告)号：US11462370B2

    公开(公告)日：2022-10-04

    申请号：US17407057

    申请日：2021-08-19

    申请人： Tetsuya Nakamura

    发明人： Tetsuya Nakamura

    IPC分类号： H01H13/04 ,  H01H13/14 ,  H01H13/10 ,  H01H13/06

    摘要： The push switch 1 includes a case 2, a pair of contacts 3 and 4, a movable contact 5, a cap 7 covering the case 2 from the upper side, and a cover 8 pressing the cap 7 from the upper side. The cover 8 includes a top plate 81 and a pair of extending portions 83 extending downward from opposite sides of the top plate 81. Each of the extending portions 83 of the cover 8 has a pair of leg portions 831 extending downward and a bridge portion 832 connecting the pair of leg portions 831. The bridge portion 832 has a pair of inclined portions 8321 formed at the lower end portion of the bridge portion 832 and inclined outward, and a cutout portion 8322 formed between the pair of inclined portions 8321.

    Swing-open type package
    10.
    发明授权
    Swing-open type package 有权
    摇摆式包装

    公开(公告)号：US08925794B2

    公开(公告)日：2015-01-06

    申请号：US12862413

    申请日：2010-08-24

    申请人： Shunsuke Tawada ,  Tetsuya Nakamura ,  Noriaki Mitsui ,  Kouya Nakamura ,  Nobuhiko Higashi ,  Hideki Mori

    发明人： Shunsuke Tawada ,  Tetsuya Nakamura ,  Noriaki Mitsui ,  Kouya Nakamura ,  Nobuhiko Higashi ,  Hideki Mori

    IPC分类号： B65D43/16 ,  B65D85/10 ,  B65D5/66

    CPC分类号： B65D5/6697 ,  B65D85/1009

    摘要： A swing-open type package has a box body (10), a lid (12) to be put onto the box body (10) from above, and a swing device connecting the lid (12) and the box body (10), the swing device including a movable rear wall portion (36) formed by a part of a rear wall of the box body (10), and a support flap (44) connecting the lid (12) and a transverse wall (21) of the box body (10), and enables a swing motion of the lid (12) when a front wall of the lid (12) is raised from the boxy body (10) so that the swing motion causes the lid (12) to tilt and open wide.

    摘要翻译： 摆动式包装具有盒体（10），从上方被放置到箱体（10）上的盖（12）和连接盖（12）和箱体（10）的摆动装置， 所述摆动装置包括由所述箱体（10）的后壁的一部分形成的可动后壁部（36）和连接所述盖（12）和所述箱体（12）的横壁（21）的支撑翼片 并且当所述盖（12）的前壁从所述手指体（10）升起时能够使所述盖（12）的摆动运动，使得所述摆动使所述盖（12）倾斜，并且 敞开。