摘要:
In an elevator, a transmission sheave is attached to a mount structure fastened to a guide rail. A speed governor rope suspended from a speed governor is coupled with an elevator car that ascends and descends in a shaft, and is wound on the transmission sheave. An idler pulley is provided for increasing a winding angle with respect to the transmission sheave by changing movement of the speed governor rope 4. A position detection apparatus is provided for detecting the position of the car in the shaft based upon the rotation of the transmission sheave. The position detection apparatus can be installed in an empty space in the shaft without the need of a repair of an existing speed governor to save the repair costs of the elevator.
摘要:
A shoe midsole has a sole plate, a plurality of blades integrally standing on the sole plate, a cover bonded to the circumference of the sole plate, and a fluid sealed between the sole plate and the cover. A first concave part in a shape equivalent to a sole of a foot is formed on the surface of the sole plate, on which the plurality of blades stand, wherein the plurality of blades are accommodated within the first concave part. The plurality of blades are aligned at a predetermined interval in a direction nearly orthogonal to the longitudinal direction of the sole plate, and some of the plurality of blades are tilted toward the toe.
摘要:
A method of controlling a wavelength-tunable laser selecting an oscillation wavelength with a combination of a plurality of wavelength selection portions of which wavelength peak is different from each other, comprising: a first step of confirming a control direction of the wavelength selection portion in a case where a setting value is changed from a first setting value for achieving the first wavelength to a second setting value for achieving the second wavelength; a second step of setting a setting value that is shifted from the second setting value in a direction that is opposite of a pre-determined changing direction on the wavelength selection portion as a prepared setting value, when the control direction confirmed in the first step is opposite to the pre-determined changing direction; and a third step of changing the prepared setting value set in the second step to the second setting value.
摘要:
The present inventors successfully produced monoclonal antibodies that are specific to only soluble Aβ oligomers, but do not recognize soluble Aβ monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.
摘要:
Disclosed is an efficient and economical method for the preparation of N-glycolyl neuraminic acid in a high purity from an inexpensive abundant source material. The method comprises dispersing body tissues of an echinodermatous marine animal Cucumaria echinata in an aqueous medium, preferably, using a dry powder of the tissues prepared in advance, in which the tissues are proteolytically decomposed to isolate N-glycolyl neuraminic acid in the form of an aqueous solution containing polypeptides as a by-product, followed by separation of N-glycolyl neuraminic acid from the aqueous solution by removing the polypeptides and purification of the compound in a process utilizing an ion-exchange treatments.
摘要:
The present inventors successfully produced monoclonal antibodies that are specific to only soluble Aβ oligomers, but do not recognize soluble Aβ monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.
摘要:
The present inventors successfully produced monoclonal antibodies that are specific to only soluble Aβ oligomers, but do not recognize soluble Aβ monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.
摘要:
It is intended to provide an antibody efficacious in diagnosing, preventing or treating Alzheimer's disease, DNA encoding the antibody, a method of screening a drug and drugs. The amino acid sequence and the gene sequence of the variable region of an antibody, which specifically recognizes a GM1 ganglioside-bound amyloid β-protein occurring in the early stage of β-amyloid fibril formation, are determined. Based on the data of the amino acid sequence and the gene sequence thus obtained, an antibody is designed.
摘要:
A mast cell surface antigen, DNA thereof and an antibody against the antigen are provided. The amino acid sequence of this mast cell surface antigen is the translation of the coding region of its DNA. The base sequence of this DNA has been clarified in the following manner. Namely, mast cells obtained by incubating cord blood monocular cells are co-incubated with primary culture of fibroblasts to give connective tissue type mast cells (MC-TC). Then mRNA is extracted from this MC-TC cell extraction and a cDNA library is constructed therefrom. Immunological screening is carried out with the use of anti-MC-TC antiserum and the base sequence of the positive clone thus obtained is identified. Owing to the clarification of the amino acid sequence of this mast cell antigen, it becomes possible to reveal the role of mast cells in the pathology of allergic diseases and thus an antibody against mast cells can be easily obtained.
摘要:
A fire detector consisting of a body and a base. An inner wall part is provided in a circumferential wall of the body in such a manner that the inner wall part can be cut away therefrom. Further, an engaging member abutting on the inner wall part is provided in the base. If it is unnecessary to lock the body to the base, the inner wall part is not cut away therefrom. In contrast, if it is necessary to lock the body to the base, the inner wall part is cut away therefrom. Thereby, the engaging member 12 can be fitted into a recess portion formed on the circumferential wall by cutting away the inner wall part therefrom. If the body is pushed against the base, a leading end of the engaging member is pushed up by the top surface of the circumferential wall. When the body being in such a state is turned in the circumferential or clockwise direction thereof to a fixing position at which the body is fixed, the leading end is fitted into the recess portion and moves downwardly. Even if the body being in this state is turned to an initial position thereof and is then detached therefrom, the leading end abuts the recess portion in the circumferential direction thereof and thus comes to be unable to be turned. Namely, the body is locked to the base thereof. Thereby, it can be selected according to the specifications of the fire detector as to whether or not the body is to be locked to the base. Consequently, the fire detector of the invention can be formed at a low cost regardless of whether or not the body is to be locked to the base of the fire detector.