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公开(公告)号：US20180354076A1
公开(公告)日：2018-12-13
申请号：US15739395
申请日：2016-04-05
申请人： KATAOKA CORPORATION
发明人： Masami SUZUKI , Norio Nishi , Junichi MATSUMOTO
CPC分类号： B23K26/38 , B23K26/0006 , B23K26/12 , C12M1/33 , C12N1/00 , C12N5/00 , C12N5/0696
摘要： In order to cut a plurality of clumps having an approximately uniform shapes and approximately uniform dimensions out of a cell aggregate which has proliferated and appropriately eliminate contamination with fragments of different shapes or dimensions, when cutting the clumps of approximately uniform shape out of the cell aggregate which has proliferated, cutting lines along which the clumps of a specific shape are cut out are set such that the area of a peripheral part of the cell aggregate which is not cut by the cutting line exceeds the surface area of one of the clumps, and the cell aggregate is cut by irradiating with laser light in such a way as to trace the cutting lines.
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公开(公告)号：US20240342825A1
公开(公告)日：2024-10-17
申请号：US18292112
申请日：2022-06-09
申请人： KATAOKA CORPORATION
发明人： Masami SUZUKI , Shoichi IMURA , Shinichi NAKASHIBA
IPC分类号： B23K26/042 , B23K26/08
CPC分类号： B23K26/042 , B23K26/0876
摘要： In order to implement a stage device for an optical instrument capable of accurately directing the optical instrument to a desired target position on an object supported by a moving stage, a stage device 2 for an optical instrument includes a table 22 configured to support an object and to move together with the object to cause an optical instrument 1 to be directed to any portion of the object; and a detection mechanism configured to detect a deviation between a target position to which the optical instrument 1 is to be directed on the object supported by the table 22 and a position to which the optical instrument 1 is actually directed.
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公开(公告)号：US20180142193A1
公开(公告)日：2018-05-24
申请号：US15576228
申请日：2016-03-25
IPC分类号： C12M1/42 , C12N5/00 , C12M1/00 , C12M1/12 , C12M1/26 , C12N1/02 , C12N13/00 , C12M1/34 , C12M1/32
CPC分类号： C12M1/42 , C12M1/005 , C12M1/3446 , C12M23/20 , C12M25/06 , C12M31/02 , C12M33/06 , C12M33/10 , C12M47/04 , C12N1/00 , C12N1/02 , C12N5/0081 , C12N13/00
摘要： A method of killing specific cells from among a group of cells cultured in a culture vessel by quick and brief laser treatment, the cell culture vessel comprising a main body and a to-be-irradiated layer attached to the main body, the to-be-irradiated layer containing an ingredient capable of absorbing laser light upon laser irradiation, the group of cells being cultured on the surface of the to-be-irradiated layer, the method comprising: applying laser light to a partial area of the to-be-irradiated layer directly below the specific cells.
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公开(公告)号：US20210079324A1
公开(公告)日：2021-03-18
申请号：US17103539
申请日：2020-11-24
IPC分类号： C12M1/42 , C12N1/00 , C12M1/00 , C12M1/34 , C12M1/12 , C12M1/32 , C12M1/26 , C12N1/02 , C12N5/00 , C12N13/00
摘要： A laser processing machine for killing specific cells from a group of cells on a surface of a layer containing an ingredient capable of absorbing laser light, the laser processing machine being configured to: control a laser light source to output laser light at 5 W or less and at a wavelength of 380 nm or greater such that the laser light source is applied to a second area on a second surface of the layer opposed to the first surface; and control an actuator to provide a relative movement between the second area where the laser light is applied and the layer at a rate of 2000 mm/sec or less such that the irradiated second area absorbs energy to generate heat that kills unwanted cells on a first area of the first surface and the laser light does not instantly kill the specific cells on the first area upon irradiation.
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公开(公告)号：US20210071121A1
公开(公告)日：2021-03-11
申请号：US17103597
申请日：2020-11-24
IPC分类号： C12M1/42 , C12N1/00 , C12M1/00 , C12M1/34 , C12M1/12 , C12M1/32 , C12M1/26 , C12N1/02 , C12N5/00 , C12N13/00
摘要： A cell culture vessel for use with a laser processing machine, including: a layer containing an ingredient that generates heat upon laser irradiation; the layer kills specific cells from among a group of cells cultured on a first surface of the layer when a second surface of the layer is irradiated with laser light having an output of 5W or less at a wavelength of 380 nm or greater and a relative movement between a second area on the second surface where the laser light is applied and the layer is at a rate of 2000 mm/sec or less such that the second area absorbs energy of the laser light to generate heat that kills the specific cells that are present on a first area of the first surface and the laser light does not instantly kill the specific cells on the first area upon irradiation with the laser light.
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