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    Device for determining information relating to a suspected occluding object
    2.
    发明授权
    Device for determining information relating to a suspected occluding object 有权

    公开(公告)号：US11583186B2

    公开(公告)日：2023-02-21

    申请号：US16480001

    申请日：2018-01-15

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Manfred Mueller ,  Arjen Van Der Horst ,  Gerhardus Wilhelmus Lucassen ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Charles Frederik Sio

    IPC分类号： A61B5/00 ,  A61B5/1459 ,  A61B5/02 ,  A61B5/026

    摘要： The present invention relates to a device for determining information relating to a suspected occluding structure. It is described to provide (210) a spectral resolving unit with at least one broadband radiation. The at least one broadband radiation comprises a first broadband radiation acquired from a region of interest within a vascular structure. An occluding structure is suspected to be located within the region of interest and wherein the first broadband radiation is associated with the suspected occluding structure. At least one spectrally resolved data set is determined (220) on the basis of the at least one broadband radiation, wherein the at least one spectrally resolved data set comprises a first spectrally resolved data set determined on the basis of the first broadband radiation. A processing unit is provided (230) with the at least one spectrally resolved data set on the basis of the at least one broadband radiation. The processing unit determines (240) information relating to the suspected occluding structure, comprising utilisation of the first spectrally resolved data set.

    Imaging system with hyperspectral camera guided probe
    3.
    发明授权
    Imaging system with hyperspectral camera guided probe 有权

    公开(公告)号：US11154199B2

    公开(公告)日：2021-10-26

    申请号：US14653554

    申请日：2014-01-22

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Bernardus Hendrikus Wilhelmus Hendriks ,  Johannes Joseph Hubertina Barbara Schleipen ,  Christian Reich ,  Gerhardus Eilhelmus Lucassen ,  Manfred Mueller ,  Vishnu Vardhan Pully

    IPC分类号： A61B5/00 ,  G06T7/70 ,  A61B8/12 ,  A61B5/1455 ,  G01J3/02 ,  G01J3/28

    摘要： A medical imaging system for identifying a target structure (TS), e.g. a tumor, in a biological tissue. A hyperspectral camera system is used for imaging a surface area (A1) of the tissue (BT), e.g. with a limited spectral resolution, but enough to allow identification of suspicious areas where the target structure (TS) may be, e.g. such areas can be visually indicated on a display to the operator. A probe (PR), e.g. an optical surface probe, is used to provide probe measurement of a smaller surface area (A2) of the tissue, but with more information indicative of the target structure. The probe is selected to provide a higher specificity with respect to identification of the target structure than the hyperspectral camera (HSC). The hyperspectral processing algorithm (PP) is then calibrated based on probe measurement data performed within the suspicious areas, thus providing a calibrated hyperspectral processing algorithm resulting in images with an enhanced sensitivity to identify the target structure. Only few probe measurements are required to significantly improve the resulting image, thereby providing a reliable and fast target structure (TS) identification.

    Determination of a treatment response index
    4.
    发明授权
    Determination of a treatment response index 有权

    公开(公告)号：US12020791B2

    公开(公告)日：2024-06-25

    申请号：US17288166

    申请日：2019-10-16

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Nicolas Daniel Marie Foin ,  Arjen Van Der Horst ,  Manfred Mueller ,  Joachim Kahlert

    IPC分类号： G16H20/00 ,  A61B5/00 ,  A61B5/02 ,  G16H50/20 ,  G16H50/30

    CPC分类号： G16H20/00 ,  A61B5/02007 ,  A61B5/4884 ,  A61B5/7275 ,  G16H50/20 ,  G16H50/30

    摘要： The present invention relates to determining a treatment response index. In order to improve and facilitate hypertension treatment procedures, a device (10) for determining a treatment response index is provided that comprises a data input (12), a data processor (14) and a data output (16). The data input is configured to receive a value (18) of at least one first measurement of a physiological parameter of a subjects vasculature under a first condition; and to provide a value (20) of at least one second measurement of the physiological parameter of the vasculature under a second condition. In the second condition, a pre-determined stimulation is provided, and the first condition is non-stimulated or at least differently stimulated. The data processor is configured to generate a treatment response index. In an example, the data output is configured to provide a classification of the subject into one of at least two groups of subjects, based on the treatment response index.

    IMAGING SYSTEM WITH HYPERSPECTRAL CAMERA GUIDED PROBE
    8.
    发明申请
    IMAGING SYSTEM WITH HYPERSPECTRAL CAMERA GUIDED PROBE 审中-公开
    具有高分辨率摄像机指导探测的成像系统

    公开(公告)号：US20160007858A1

    公开(公告)日：2016-01-14

    申请号：US14653554

    申请日：2014-01-22

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Bernardus Hendrikus Wilhelmus Hendriks ,  Johannes Joseph Hubertina Barbara Schleipen ,  Christian Reich ,  Gerhardus Eilhelmus Lucassen ,  Manfred Mueller ,  Vishnu Vardhan Pully

    IPC分类号： A61B5/00 ,  A61B8/12

    摘要： A medical imaging system for identifying a target structure (TS), e.g. a tumor, in a biological tissue. A hyperspectral camera system is used for imaging a surface area (A1) of the tissue (BT), e.g. with a limited spectral resolution, but enough to allow identification of suspicious areas where the target structure (TS) may be, e.g. such areas can be visually indicated on a display to the operator. A probe (PR), e.g. an optical surface probe, is used to provide probe measurement of a smaller surface area (A2) of the tissue, but with more information indicative of the target structure. The probe is selected to provide a higher specificity with respect to identification of the target structure than the hyperspectral camera (HSC). The hyperspectral processing algorithm (PP) is then calibrated based on probe measurement data performed within the suspicious areas, thus providing a calibrated hyperspectral processing algorithm resulting in images with an enhanced sensitivity to identify the target structure. Only few probe measurements are required to significantly improve the resulting image, thereby providing a reliable and fast target structure (TS) identification.

    摘要翻译： 用于识别目标结构（TS）的医学成像系统，例如， 一种肿瘤，在生物组织中。 高光谱相机系统用于对组织（BT）的表面积（A1）进行成像，例如， 具有有限的光谱分辨率，但足以允许识别目标结构（TS）可能的可疑区域，例如， 这样的区域可以在显示器上在操作者上可视地指示。 探针（PR），例如 光学表面探针用于提供组织的较小表面积（A2）的探针测量，但具有指示目标结构的更多信息。 选择探针以提供比高光谱相机（HSC）更高的针对目标结构的识别的特异性。 然后基于在可疑区域内进行的探测测量数据校准高光谱处理算法（PP），从而提供校准的高光谱处理算法，从而产生具有增强灵敏度的图像以识别目标结构。 仅需要很少的探针测量来显着改善所得到的图像，从而提供可靠和快速的目标结构（TS）识别。

    Catheter with optical sensing
    10.
    发明授权
    Catheter with optical sensing 有权

    公开(公告)号：US11045082B2

    公开(公告)日：2021-06-29

    申请号：US15749636

    申请日：2016-08-03

    申请人： KONINKLIJKE PHILIPS N.V.

    发明人： Manfred Mueller

    IPC分类号： A61B1/06 ,  A61B1/005 ,  A61B1/267 ,  A61B1/00 ,  A61B5/107 ,  A61B5/00 ,  A61M25/00 ,  G02B23/24 ,  G03B15/05 ,  G01B11/245 ,  G01B11/25 ,  G03B37/00 ,  A61M25/01

    摘要： A catheter (12) has an image sensing system (S1-S5) for imaging the interior wall of a passageway in which the catheter is to be located. The catheter has a radial imaging system comprising a light source arrangement for generating a light output radially around the catheter and an image sensor for receiving the generally radial light after the light has been scattered back by the interior wall. The catheter is positioned within the passageway with a known position and orientation, for example a known angle with respect to the anterior-posterior plane along the length of the catheter, so that it is known where along the catheter length, and at which angular position around the catheter, it is close to the passageway wall. The light output has a different intensity at different radial directions and/or the catheter comprises a light transmission arrangement which gives rise to different transmission of the light output at different radial directions. These provide alternative measures to reduce the light received by the image sensor, thereby to prevent blooming in the captured image.