公开(公告)号：US20230347025A1

公开(公告)日：2023-11-02

申请号：US18348247

申请日：2023-07-06

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Myoung-Ryul OK ,  Jimin PARK ,  Yu Chan KIM ,  Hyun Kwang SEOK ,  Hyung-Seop HAN ,  Hojeong JEON ,  Hyunseon SEO ,  Jee-Wook LEE ,  Jin Kyung JEON ,  Gayoung JUNG ,  Jong Woong PARK ,  Ji Hun PARK

IPC: A61L31/16 ,  A61B17/86 ,  A61B17/80 ,  A61K9/00 ,  A61K33/00 ,  A61L31/02 ,  F16B35/04 ,  A61F2/28

CPC classification number: A61L31/16 ,  A61B17/8605 ,  A61B17/80 ,  A61K9/0024 ,  A61K33/00 ,  A61L31/022 ,  F16B35/04 ,  A61F2/2846 ,  A61B17/866 ,  A61B2017/00893

Abstract: Provided is an implant having a controlled generation rate of reactive oxygen species and a method of controlling generation of reactive oxygen species using the same. The implant having a controlled generation rate of reactive oxygen species according to the present invention includes a body formed of a metallic material and having a groove, a first filling metal filling one region of the groove, and a second filling metal filling the groove on the first filling metal, wherein the second filling metal has an ionization tendency different from that of the first filling metal.

公开(公告)号：US20200071834A1

公开(公告)日：2020-03-05

申请号：US16555079

申请日：2019-08-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hojeong JEON ,  Seung Hoon UM ,  Yongwoo CHUNG ,  Hyunseon SEO ,  Yu Chan KIM ,  Myoung-Ryul OK ,  Hyun Kwang SEOK

IPC: C23C22/03 ,  A61L27/06 ,  A61L27/32 ,  C23C22/78 ,  C23C22/82

Abstract: Provided is a method of forming an apatite coating, including brining an apatite-forming precursor solution including Ca2+ ions and PO43− ions into direct contact with at least one region of the substrate, emitting a laser beam onto the region of the substrate in direct contact with the precursor solution through the precursor solution, and forming apatite on the region onto which the laser beam is emitted.

公开(公告)号：US20150064358A1

公开(公告)日：2015-03-05

申请号：US14471535

申请日：2014-08-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyun Kwang SEOK ,  Yu Chan KIM ,  eun young CHOI ,  Kyeong Ho BAIK ,  Hoon JEONG

IPC: C23C4/10 ,  C23C4/12

CPC classification number: C23C4/11 ,  C23C4/134 ,  C23C4/137

Abstract: A coating material for a thermal spray coating having corrosion resistance and low reactivity, a preparation method thereof, and a coating method thereof are provided. The coating material for thermal spray coating has a composition of Mg1−xY2xO2x+1 (where x is 0.01 to 0.99).

Abstract translation: 提供了具有耐腐蚀性和低反应性的热喷涂用涂料，其制备方法及其涂布方法。 用于热喷涂的涂料具有Mg1-xY2xO2x + 1（其中x为0.01至0.99）的组成。

公开(公告)号：US20140271334A1

公开(公告)日：2014-09-18

申请号：US14053017

申请日：2013-10-14

Applicant: Korea Institute of Science and Technology

Inventor： Yu Chan KIM ,  Hyun Kwang SEOK ,  Do Hyang KIM ,  Jeong Kyun KIM

IPC: A61L31/02 ,  C22C23/04

CPC classification number: A61L31/022 ,  A61L31/148 ,  C22C23/04

Abstract: A biodegradable Mg-based alloy and implant are provided. The biodegradable Mg-based alloy is represented with a composition equation Mg100-a-b-cZnaLibZrc, wherein a, b, and c of the composition equation are wt % of Zn, Li, and Zr, respectively, and satisfy 0

Abstract translation: 提供可生物降解的Mg基合金和植入物。 可生物降解的Mg基合金由组成式Mg100-ab-cZnaLibZrc表示，其中组成方程的a，b和c分别为Zn，Li和Zr的wt％，满足0

公开(公告)号：US20210381112A1

公开(公告)日：2021-12-09

申请号：US17338110

申请日：2021-06-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hojeong JEON ,  Seung Hoon UM ,  Jae Ho PARK ,  Justin Jihong CHUNG ,  Hyunseon SEO ,  Hyung-Seop HAN ,  Yu Chan KIM ,  Myoung-Ryul OK ,  Hyun Kwang SEOK

IPC: C23C26/00 ,  B23K26/122 ,  B23K26/352 ,  C01B25/32

Abstract: Provided is a method of forming an apatite coating, the method including immersing a substrate in an apatite-forming precursor solution including Ca2+ ions and PO43− ions, emitting a laser beam onto a surface of the substrate immersed in the precursor solution, and forming an apatite coating in a region exposed to the laser beam, wherein an output power of the laser beam is set within a range enabling the surface of the substrate to be melted.

公开(公告)号：US20200345479A1

公开(公告)日：2020-11-05

申请号：US16836925

申请日：2020-04-01

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hojeong JEON ,  Myoung-Ryul OK ,  Yu Chan KIM ,  Hyun Kwang SEOK

IPC: A61F2/16

Abstract: Provided is an intraocular lens including: an optic portion; and a haptic portion extending from the optic portion, wherein a pattern having ridges and grooves is formed on at least one of the optic portion and the haptic portion, and each of the grooves has a nanostructure roughness. Provided also is a method of manufacturing an intraocular lens, the method including: seating an object to be processed including an optic portion and at least one haptic portion extending from the optic portion, processing a predetermined pattern for guiding cells by performing laser irradiation on the haptic portion and the optic portion, forming grooves having a nanostructure surface roughness in the predetermined pattern formed by laser beams, and the surface of each of the grooves has an average roughness Ra less than 200 nm.

公开(公告)号：US20160095698A1

公开(公告)日：2016-04-07

申请号：US14744190

申请日：2015-06-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hojeong JEON ,  Chunga KWON ,  Yu Chan KIM ,  Hyun Kwang SEOK ,  Jee-Wook LEE ,  Hyun Soo LEE ,  Choun Ki JOO

IPC: A61F2/16

CPC classification number: A61F2/16 ,  A61F2002/0081 ,  A61F2002/009 ,  A61F2002/1681

Abstract: Disclosed is an intraocular lens with a fine pattern including an optic having a circular shape, and a plurality of haptics connected to a periphery of the optic, and a pattern is formed on a surface of a partial area of at least one of the optic and the haptics.

Abstract translation: 公开了具有包括圆形形状的光学元件的精细图案的眼内透镜和连接到光学元件的周边的多个触觉件，并且在光学元件和光学元件中的至少一个的局部区域的表面上形成图案， 触觉。

公开(公告)号：US20210220631A1

公开(公告)日：2021-07-22

申请号：US17153969

申请日：2021-01-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  Industry-University Cooperation Foundation Hanyang University ERICA Campus

Inventor： Myoung-Ryul OK ,  So Yeon KIM ,  Yoon Ki JOUNG ,  Yu Chan KIM ,  Hyun Kwang SEOK ,  Hyung-Seop HAN ,  Hojeong JEON ,  Hyunseon SEO ,  Inho KIM ,  Kyoung Won PARK ,  Yongwoo CHUNG ,  Jaekyun KIM

IPC: A61M37/00 ,  A61N5/06

Abstract: Provided are phototherapeutic needle patches usable for phototherapy by using needle patches capable of injecting drugs or cosmetic substances to patients, and methods of manufacturing the same. A phototherapeutic needle patch may include a patch body attachable to skin of a patient, at least one microneedle protruding from the patch body, one end of the microneedle configured to deliver a drug through stratum corneum of the skin to inner tissues of the skin, and light grooves formed in a concave shape along a length direction of the microneedle in such a manner that therapeutic light radiated from a light source for phototherapy easily penetrates into the skin along the microneedle.

公开(公告)号：US20200015961A1

公开(公告)日：2020-01-16

申请号：US16512400

申请日：2019-07-16

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  ADVANCED TECHNOLOGY INC.

Inventor： Ho Jeong JEON ,  Myoung Ryul OK ,  Yu Chan KIM ,  Hyun Kwang SEOK ,  Choun Ki JOO ,  Byoung Chan CHOI

IPC: A61F2/16

Abstract: There is provided an intraocular lens including an optic portion having a circular shape from one side thereof and including a first pattern which includes a ridge and a groove, and a plurality of haptic portions extending from an outer circumferential edge of the optic portion and each including a second pattern which includes a ridge and a groove, in which at least one of the ridges included in the first pattern and the second pattern and at least one of the grooves included in the first pattern and the second pattern includes a section in which a width is formed differently.

公开(公告)号：US20180238780A1

公开(公告)日：2018-08-23

申请号：US15753115

申请日：2016-08-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hojeong JEON ,  Indong JUN ,  Kangwon LEE ,  Hyung-Seop HAN ,  Jimin PARK ,  Myoung-Ryul OK ,  Yu Chan KIM ,  Hyun Kwang SEOK

IPC: G01N1/31 ,  G01N33/50

CPC classification number: G01N1/31 ,  B01J19/0046 ,  B01J2219/00382 ,  B01J2219/0043 ,  B01J2219/00743 ,  B82Y40/00 ,  C12N5/0068 ,  C12N2533/74 ,  C12N2535/10 ,  G01N1/30 ,  G01N33/5005

Abstract: A cell patterning material, a method of preparing the cell patterning material, a cell patterning method using the cell patterning material, and a biosensor including patterned cells obtained by using the cell patterning method are provided. According to the present disclosure, cells may be conveniently and efficiently patterned and the time for applying external stimulation for patterning may be controlled. In addition, the patterned cells may have an excellent proliferation rate and excellent differentiation efficiency, and may be re-patterned in a different direction, and High-throughput screening using the patterned cells is possible.