公开(公告)号：US5114466A

公开(公告)日：1992-05-19

申请号：US534060

申请日：1990-06-06

申请人： Kengo Oda ,  Koichi Moriyasu ,  Masao Hayashi ,  Makoto Nishida ,  Masami Oyamada ,  Akie Fujiwara ,  Junko Watanabe

发明人： Kengo Oda ,  Koichi Moriyasu ,  Masao Hayashi ,  Makoto Nishida ,  Masami Oyamada ,  Akie Fujiwara ,  Junko Watanabe

IPC分类号： A01N43/36 ,  C07D207/26 ,  C07D207/273

CPC分类号： C07D207/273 ,  A01N43/36

摘要： 1-(3-Substituted benzyl)-3-halogeno-4-(1-halogenoalkyl)-2-pyrrolidinones of the general formula (I): ##STR1## where X represents a hydrogen atom or halogen atom, Y and Z each represents a chlorine atom or bromine atom, and R represents an alkyl group with 2 to 4 carbon atoms, are herbicides useful in rice paddy fields to control weeds therein, especially Echinochloa crusgalli and can be produced subjecting the corresponding 3-dihalogeno compounds to dehalogenation to remove one of the halogen atoms or by cyclizing a 2,2-dihalogenoacetamide derivative represented by the general formula (II) under the presence of an appropriate catalyst; ##STR2## in which X, Y, Z and R respectively have the same meanings as described above.

公开(公告)号：US5131947A

公开(公告)日：1992-07-21

申请号：US494725

申请日：1990-03-14

申请人： Kengo Oda ,  Koichi Moriyasu ,  Kiyoshi Arai ,  Kanji Tomiya ,  Miura Tohru ,  Makoto Nishida ,  Masami Oyamada ,  Akie Fujiwara

发明人： Kengo Oda ,  Koichi Moriyasu ,  Kiyoshi Arai ,  Kanji Tomiya ,  Miura Tohru ,  Makoto Nishida ,  Masami Oyamada ,  Akie Fujiwara

IPC分类号： A01N43/36 ,  C07D207/26 ,  C07D207/27

CPC分类号： C07D207/27 ,  A01N43/36

摘要： 4-Ethyl-3-(phenyl)-1-(3-trifluoromethylphenyl)-2-pyrrolidinones and corresponding compounds bearing a p-substituent on the 1-position phenyl group and/or a substituent on the 3-position phenyl group exhibit selective herbicidal activities against various weeds which cause problems in rice or upland fields, even at extremely low application rates. They can be prepared by reductive dehalogenation of a corresponding .alpha.-haloethyl substituted pyrrolidinone or reductive cyclization of a corresponding N-2-butenyl-N-(substituted phenyl)-haloacetyl-3-trifluoromethylaniline.

公开(公告)号：US5123954A

公开(公告)日：1992-06-23

申请号：US755366

申请日：1991-09-06

申请人： Koichi Moriyasu ,  Kengo Oda ,  Kanji Tomiya ,  Tohru Miura ,  Makoto Nishida ,  Sachiko Hibi

发明人： Koichi Moriyasu ,  Kengo Oda ,  Kanji Tomiya ,  Tohru Miura ,  Makoto Nishida ,  Sachiko Hibi

IPC分类号： A01N43/36 ,  C07D207/26

CPC分类号： C07D207/26 ,  A01N43/36

摘要： A 3,4-cis isomer of 4-ethyl-1-(substituted phenyl)-3-substituted phenyl)pyrrolidin-2-one, when reacted with a base, can be effectively convered into a 3,4-trans isomer thereof which has a high herbicidal activity useful as an effective ingredient for a herbicidal composition. Furthermore, 3,4-trans-4-ethyl-1-(substituted phenyl)-3-(substituted phenyl)pyrrolidin-2-one compounds represented by the formula (III) ##STR1## (wherein R.sup.2 is an isopropyl group, and X is a fluorine atom, chlorine atom or bromine atom substituted at the 3-position, or fluorine atoms substituted at the 3- and 4-positions or the 3- and 5-positions) have an extremely excellent activity particularly as a herbicidally active ingredient of the herbicidal composition for rice paddy fields.

公开(公告)号：US4906277A

公开(公告)日：1990-03-06

申请号：US315121

申请日：1989-02-24

申请人： Kengo Oda ,  Tsutomu Ishii ,  Yukiharu Fukushi ,  Yuji Enomoto ,  Makoto Nishida ,  Yoshikata Hojo

发明人： Kengo Oda ,  Tsutomu Ishii ,  Yukiharu Fukushi ,  Yuji Enomoto ,  Makoto Nishida ,  Yoshikata Hojo

IPC分类号： A01N43/80 ,  C07D261/04

CPC分类号： A01N43/80 ,  C07D261/04

摘要： Novel 3-substituted phenyl-2-isoxazoline-5-carboxylic acids or esters thereof. These compounds have excellent properties as plant growth regulators.

公开(公告)号：US4889551A

公开(公告)日：1989-12-26

申请号：US92197

申请日：1987-09-02

申请人： Kengo Oda ,  Tsutomu Ishii ,  Yukiharu Fukushi ,  Yuji Enomoto ,  Makoto Nishida ,  Yoshikata Hojo

发明人： Kengo Oda ,  Tsutomu Ishii ,  Yukiharu Fukushi ,  Yuji Enomoto ,  Makoto Nishida ,  Yoshikata Hojo

IPC分类号： A01N43/80 ,  C07D261/04

CPC分类号： A01N43/80 ,  C07D261/04

摘要： Novel 3-substituted phenyl-2-isoxazoline-5-carboxylic acids or esters thereof. These compounds have excellent properties as plant growth regulators.

摘要翻译： 新的3-取代的苯基-2-异恶唑啉-5-羧酸或其酯。 这些化合物作为植物生长调节剂具有优异的性质。

公开(公告)号：US4986846A

公开(公告)日：1991-01-22

申请号：US451678

申请日：1989-12-18

申请人： Masatoshi Gohbara ,  Tamotsu Asano ,  Shuji Ozawa ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Makoto Nishida ,  Junko Watanabe ,  Naoki Sato

发明人： Masatoshi Gohbara ,  Tamotsu Asano ,  Shuji Ozawa ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Makoto Nishida ,  Junko Watanabe ,  Naoki Sato

IPC分类号： A01N43/54 ,  C07D239/60

CPC分类号： C07D239/60 ,  A01N43/54

摘要： Disclosed are herbicidally active pyrimidine derivatives of the formula ##STR1## wherein R represents a hydrogen atom or an etherifying group, e.g., a lower alkyl, lower alkenyl, lower alkynyl, phenyl-substituted lower alkenyl, lower haloalkenyl, cycloalkyl, substituted phenyl-substituted lower alkenyl or phenyl-substituted lower alkynyl group; or a group represented by the following formula: ##STR2## wherein R.sup.1 represents a hydrogen atom or a lower alkyl group, X a halogen atom or a lower alkyl or lower alkoxyl group, m and n individually 0-2, and when m is 2, both Xs may be the same or different, and herbicidal compositions containing the same, alone or in combination with another herbicidally active compound, the pyrimidine derivatives being prepared by reaction of 2-(4,6-dimethoxy-2-pyrimidinyloxy)benzaldehyde with NH.sub.2 OR or with a salt of hydroxylamine followed by reaction with a halide of the formula RY wherein R has the same value as above and Y is Cl, Br or I.

公开(公告)号：US5053070A

公开(公告)日：1991-10-01

申请号：US565071

申请日：1990-08-09

申请人： Masatoshi Gohbara ,  Tamotsu Asano ,  Shuji Ozawa ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Makoto Nishida ,  Junko Watanabe ,  Naoki Sato

发明人： Masatoshi Gohbara ,  Tamotsu Asano ,  Shuji Ozawa ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Makoto Nishida ,  Junko Watanabe ,  Naoki Sato

IPC分类号： A01N43/54 ,  C07D239/60

CPC分类号： C07D239/60 ,  A01N43/54

摘要： Disclosed are herbicidally active pyrimidine derivatives of the formula ##STR1## wherein R represents a hydrogen atom or an etherifying group, e.g., a lower alkyl, lower alkenyl, lower alkynyl, phenyl-substituted lower alkenyl, lower haloalkenyl, cycloalkyl, substituted phenyl-substituted lower alkenyl or phenyl-substituted lower alkynyl group; or a group represented by the following formula: ##STR2## wherein R.sup.1 represents a hydrogen atom or a lower alkyl group, X a halogen atom or a lower alkyl or lower alkoxyl group, m and n individually 0-2, and when m is 2, both Xs may be the same or different, and herbicidal compositions containing the same, alone or in combination with another herbicidally active compound, the pyrimidine derivatives being prepared by reaction of 2-(4,6-dimethoxy-2-pyrimidinyloxy)benzaldehyde with NH.sub.2 OR or with a salt of hydroxylamine followed by reaction with a halide of the formula RY wherein R has the same value as above and Y is Cl, Br or I.

公开(公告)号：US20130323805A1

公开(公告)日：2013-12-05

申请号：US13823433

申请日：2011-09-05

申请人： Atsushi Kobayashi ,  Jihoon Cheon ,  Norihiro Takeuchi ,  Makoto Nishida ,  Yuji Tanaka ,  Shin-ichi Minegishi

发明人： Atsushi Kobayashi ,  Jihoon Cheon ,  Norihiro Takeuchi ,  Makoto Nishida ,  Yuji Tanaka ,  Shin-ichi Minegishi

IPC分类号： C12P7/56 ,  C12P7/40

CPC分类号： C12P7/56 ,  B01D61/18 ,  B01D63/02 ,  B01D65/02 ,  B01D71/34 ,  B01D2311/10 ,  B01D2321/04 ,  B01D2321/08 ,  B01D2321/168 ,  C12M33/14 ,  C12M39/00 ,  C12P1/00 ,  C12P7/40

摘要： A method of producing chemicals through continuous fermentation includes washing a membrane with a washing liquid supplied from a permeate side of a membrane unit in a continuous fermentation; filtering a culture medium containing a fermentation feedstock, a chemical and a microbe or a cultured cell through a separation membrane; collecting the chemical from a filtrate; retaining or refluxing unfiltered remains in the culture medium; and adding a fermentation feedstock to the culture medium, wherein the washing liquid is high-temperature water having a temperature higher than a temperature of the culture medium and of 150° C. or less, and a concentration of the microbe in a fermenter is controlled by supplying the washing liquid.

摘要翻译： 通过连续发酵生产化学品的方法包括在连续发酵中用从膜单元的渗透侧供给的洗涤液洗涤膜; 通过分离膜过滤含有发酵原料，化学品和微生物或培养细胞的培养基; 从滤液中收集化学物质; 在培养基中保留或回流未过滤的残留物; 向培养基中添加发酵原料，其中，洗涤液是温度高于培养基温度且150℃以下的高温水，控制发酵罐中微生物的浓度 通过供给洗涤液。

公开(公告)号：US20130149745A1

公开(公告)日：2013-06-13

申请号：US13575039

申请日：2011-01-24

申请人： Jihoon Cheon ,  Shin-ichi Minegishi ,  Makoto Nishida ,  Norihiro Takeuchi

发明人： Jihoon Cheon ,  Shin-ichi Minegishi ,  Makoto Nishida ,  Norihiro Takeuchi

IPC分类号： C12P7/56 ,  C12P7/14 ,  C12P7/46

CPC分类号： C12P7/56 ,  B01D63/02 ,  B01D69/02 ,  B01D69/081 ,  B01D69/084 ,  B01D71/34 ,  B01D2325/20 ,  B01D2325/24 ,  C12P7/06 ,  C12P7/14 ,  C12P7/46 ,  Y02E50/17

摘要： A method produces a chemical by fermentation including: filtering a liquid containing a feedstock, the chemical, and bacterial, microbial or cultured cells through a membrane to recover the chemical from the filtrate; retaining or refluxing unfiltered liquid in the liquid; and adding the feedstock to the liquid, wherein the membrane is a porous hollow-fiber membrane including a polyvinylidene fluoride resin, the porous hollow-fiber membrane having an average pore size of 0.001 μm to 10.0 μm, pure water permeability coefficient at 50 kPa at 25° C. of 0.5 m3/m2/hr to 15 m3/m2/hr, breaking strength of 5 MPa to 20 MPa, elongation at break of 30% to 200%, crimping degree of 1.3 to 2.5, porosity of not less than 40%, and critical surface tension of 45 mN/m to 75 mN/m.

摘要翻译： 一种方法通过发酵生产化学品，包括：通过膜过滤含有原料，化学和细菌，微生物或培养细胞的液体，以从滤液中回收化学品; 在液体中保留或回流未过滤的液体; 并将原料添加到液体中，其中所述膜是包含聚偏二氟乙烯树脂的多孔中空纤维膜，所述多孔中空纤维膜的平均孔径为0.001μm至10.0μm，在50kPa下的纯水渗透系数为 25℃为0.5m 3 / m 2 / hr〜15m 3 / m 2 / hr，断裂强度为5MPa〜20MPa，断裂伸长率为30〜200％，卷曲度为1.3〜2.5，孔隙率为 40％，临界表面张力为45mN / m至75mN / m。

公开(公告)号：US20120270286A1

公开(公告)日：2012-10-25

申请号：US13508918

申请日：2010-11-10

申请人： Norihiro Takeuchi ,  Shin-ichi Minegishi ,  Jihoon Cheon ,  Makoto Nishida ,  Takashi Mimitsuka ,  Hironobu Suzuki ,  Katsushige Yamada ,  Hideki Sawai ,  Ichiro Kumo

发明人： Norihiro Takeuchi ,  Shin-ichi Minegishi ,  Jihoon Cheon ,  Makoto Nishida ,  Takashi Mimitsuka ,  Hironobu Suzuki ,  Katsushige Yamada ,  Hideki Sawai ,  Ichiro Kumo

IPC分类号： C12M1/12 ,  C12P7/56

CPC分类号： B01D63/04 ,  B01D63/022 ,  B01D63/023 ,  C12M29/16 ,  C12P7/56

摘要： A hollow fiber membrane module for use in production of a chemical substance, which is used in continuous fermentation including filtering a fermentation broth of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation broth or refluxing the concentrated solution, and adding a fermentation raw material to the fermentation broth, wherein a large number of hollow fiber membrane bundles are accommodated in a tubular case, at least one end part of each of the bundles is fixed on the tubular case by a hollow fiber membrane bundling member with an end face of each of the hollow fiber membranes open, and the hollow fiber membrane bundling member is made of a synthetic resin having a hardness retention rate after contact with saturated steam at 121° C. for 24 hours of 95% or more.

摘要翻译： 一种用于生产化学物质的中空纤维膜组件，用于连续发酵，包括通过中空纤维膜过滤微生物或培养细胞的发酵液，从滤液中收集化学物质，保留浓缩溶液 在发酵液中或回流浓缩溶液，向发酵液中加入发酵原料，其中将大量中空纤维膜束容纳在管状壳体中，每个束的至少一个端部固定在 通过中空纤维膜捆扎构件的中空纤维膜捆扎构件的中空纤维膜的端面打开，中空纤维膜束紧构件由在121℃的饱和蒸气接触后的硬度保持率的合成树脂制成， 持续24小时95％以上。