公开(公告)号：US20140103996A1

公开(公告)日：2014-04-17

申请号：US14118380

申请日：2012-08-24

申请人： Kenichi Horiguchi ,  Katsuya Kato ,  Kenji Mukai ,  Naoko Matsunaga ,  Morishige Hieda ,  Kazutomi Mori

发明人： Kenichi Horiguchi ,  Katsuya Kato ,  Kenji Mukai ,  Naoko Matsunaga ,  Morishige Hieda ,  Kazutomi Mori

IPC分类号： H03F1/52 ,  H03F3/24

CPC分类号： H03F3/24 ,  H03F1/0233 ,  H03F1/0261 ,  H03F1/0272 ,  H03F1/3247 ,  H03F1/52 ,  H03F1/56 ,  H03F3/189 ,  H03F2200/387 ,  H03F2200/408 ,  H03F2200/411 ,  H04B1/0458

摘要： A front-end amplifier has an impedance detector that detects an impedance seen looking into an antenna side from a power amplifier from a radio-frequency signal output from the power amplifier and a radio-frequency signal reflected from the antenna, in which a control circuit decides on whether the impedance detected by the impedance detector belongs to a specific region or not, and controls, if the impedance belongs to the specific region, at least one of the bias condition of the power amplifier and the impedance of a variable-matching circuit.

摘要翻译： 前端放大器具有阻抗检测器，其从功率放大器输出的射频信号和从天线反射的射频信号检测从功率放大器看到的天线侧的阻抗，其中控制电路 决定阻抗检测器检测到的阻抗是否属于特定区域，并且如果阻抗属于特定区域，则控制功率放大器的偏置条件和可变匹配电路的阻抗中的至少一个 。

公开(公告)号：US20130113561A1

公开(公告)日：2013-05-09

申请号：US13810388

申请日：2010-10-21

申请人： Kenichi Horiguchi ,  Naoko Matsunaga ,  Hiroshi Otsuka ,  Masatoshi Nakayama ,  Kazuhiro Iyomasa ,  Akira Inoue

发明人： Kenichi Horiguchi ,  Naoko Matsunaga ,  Hiroshi Otsuka ,  Masatoshi Nakayama ,  Kazuhiro Iyomasa ,  Akira Inoue

IPC分类号： H03F3/04

CPC分类号： H03F3/04 ,  H03F1/0277 ,  H03F3/19 ,  H03F3/245 ,  H03F3/60 ,  H03F3/72 ,  H03F2203/7239

摘要： An output mode switching amplifier, including: a transistor for signal amplification connected between a first node on an input side and a second node on an output side; a bypass path for bypassing the transistor between the first node and the second node; a voltage control circuit for switching whether to apply a bias voltage to the transistor so that a transmission signal is amplified by the transistor or to output a transmission signal via the bypass path without amplifying the transmission signal by the transistor; and a second-harmonic reflection circuit connected to the bypass path, for reflecting a second harmonic of the transmission signal.

摘要翻译： 一种输出模式切换放大器，包括：用于信号放大的晶体管，连接在输入侧的第一节点和输出侧的第二节点之间; 用于绕过第一节点和第二节点之间的晶体管的旁路路径; 电压控制电路，用于切换是否向晶体管施加偏置电压，使得透射信号被晶体管放大或经由旁路路径输出发送信号，而不会由晶体管放大发送信号; 以及连接到所述旁路路径的二次谐波反射电路，用于反射所述发送信号的二次谐波。

公开(公告)号：US20130249626A1

公开(公告)日：2013-09-26

申请号：US13992317

申请日：2011-11-09

申请人： Naoko Matsunaga ,  Kenichi Horiguchi ,  Hiroshi Otsuka ,  Masatoshi Nakayama ,  Kazuhiro Iyomasa ,  Kazuya Yamamoto ,  Akira Inoue

发明人： Naoko Matsunaga ,  Kenichi Horiguchi ,  Hiroshi Otsuka ,  Masatoshi Nakayama ,  Kazuhiro Iyomasa ,  Kazuya Yamamoto ,  Akira Inoue

IPC分类号： H03F1/02

CPC分类号： H03F1/0277 ,  H03F1/34 ,  H03F1/56 ,  H03F3/45475 ,  H03F3/72 ,  H03F2200/222 ,  H03F2200/387 ,  H03F2200/411 ,  H03F2203/45526 ,  H03F2203/45528 ,  H03F2203/45534 ,  H03F2203/45536 ,  H03F2203/7215 ,  H03F2203/7221 ,  H03F2203/7236 ,  H03G1/0088 ,  H03G3/3042

摘要： A multiple power mode amplifier includes: N amplifiers connected in series via switches; and a control circuit for controlling the N amplifiers in accordance with the output modes. P amplifiers out of the N amplifiers constitute a driver amplifier, and constitute a negative feedback amplifier including a feedback circuit for negatively feeding back its own output signal to its own input side. N−P amplifiers constitute a final stage amplifier connected in series to the negative feedback amplifier in a disconnectable manner. The control circuit is configured to: in a first output mode, disconnect the final stage amplifier from the negative feedback amplifier, and disable the feedback circuit; and in a second output mode, connect the final stage amplifier in series to the negative feedback amplifier, and enable the feedback circuit.

摘要翻译： 多功率模式放大器包括：通过开关串联连接的N个放大器; 以及根据输出模式控制N个放大器的控制电路。 N个放大器中的P放大器构成驱动器放大器，并构成负反馈放大器，其包括用于将其自身的输出信号负反馈给其自身输入侧的反馈电路。 N-P放大器构成以可断开方式与负反馈放大器串联连接的最后级放大器。 控制电路被配置为：在第一输出模式下，将最终级放大器与负反馈放大器断开，并且禁用反馈电路; 并且在第二输出模式中，将最后级放大器串联连接到负反馈放大器，并使能反馈电路。

公开(公告)号：US20100277236A1

公开(公告)日：2010-11-04

申请号：US12746363

申请日：2008-12-17

申请人： Kenichi Horiguchi ,  Naoko Matsunaga ,  Ryoji Hayashi

发明人： Kenichi Horiguchi ,  Naoko Matsunaga ,  Ryoji Hayashi

IPC分类号： H03F1/26

CPC分类号： H04B1/0475 ,  H03F1/30 ,  H03F1/3241 ,  H03F1/3247 ,  H03F3/189 ,  H03F3/245 ,  H03F2200/204 ,  H03F2200/207 ,  H03F2200/447 ,  H03F2200/451 ,  H03F2201/3209 ,  H03F2201/3224 ,  H03F2201/3233 ,  H04B2001/0425 ,  H04L27/368

摘要： Provided is a predistorter which compensates for a memory effect occurring in an amplifier used in a communication device, especially an electric memory effect as well. The predistorter includes: a distortion compensation circuit (8) for compensating for a nonlinear distortion caused by an amplifier (3), in which the distortion compensation circuit outputs a predistortion signal to be input to the amplifier. The predistorter includes: first filter section (21) which is connected between the distortion compensation circuit and the amplifier, for compensating for a frequency characteristic appearing in a signal component occurring in an entire analog circuit including the amplifier; and second filter section (22) which is connected between the distortion compensation circuit and the first filter section or between the first filter section and the amplifier, for compensating for a frequency characteristic appearing in a distortion component occurring in the amplifier.

摘要翻译： 提供了一种预失真器，其补偿在通信设备中使用的放大器中发生的存储器效应，特别是电存储器效应。 预失真器包括：用于补偿由放大器（3）引起的非线性失真的失真补偿电路（8），其中失真补偿电路输出要输入到放大器的预失真信号。 预失真器包括：连接在失真补偿电路和放大器之间的第一滤波器部分（21），用于补偿出现在包括放大器的整个模拟电路中的信号分量中出现的频率特性; 和连接在失真补偿电路和第一滤波器部分之间或第一滤波器部分和放大器之间的第二滤波器部分（22），用于补偿出现在放大器中出现的失真分量中的频率特性。

公开(公告)号：US08040182B2

公开(公告)日：2011-10-18

申请号：US12746363

申请日：2008-12-17

申请人： Kenichi Horiguchi ,  Naoko Matsunaga ,  Ryoji Hayashi

发明人： Kenichi Horiguchi ,  Naoko Matsunaga ,  Ryoji Hayashi

IPC分类号： H03F1/26

CPC分类号： H04B1/0475 ,  H03F1/30 ,  H03F1/3241 ,  H03F1/3247 ,  H03F3/189 ,  H03F3/245 ,  H03F2200/204 ,  H03F2200/207 ,  H03F2200/447 ,  H03F2200/451 ,  H03F2201/3209 ,  H03F2201/3224 ,  H03F2201/3233 ,  H04B2001/0425 ,  H04L27/368

摘要： Provided is a predistorter which compensates for a memory effect occurring in an amplifier used in a communication device, especially an electric memory effect as well. The predistorter includes: a distortion compensation circuit (8) for compensating for a nonlinear distortion caused by an amplifier (3), in which the distortion compensation circuit outputs a predistortion signal to be input to the amplifier. The predistorter includes: first filter section (21) which is connected between the distortion compensation circuit and the amplifier, for compensating for a frequency characteristic appearing in a signal component occurring in an entire analog circuit including the amplifier; and second filter section (22) which is connected between the distortion compensation circuit and the first filter section or between the first filter section and the amplifier, for compensating for a frequency characteristic appearing in a distortion component occurring in the amplifier.

摘要翻译： 提供了一种预失真器，其补偿在通信设备中使用的放大器中发生的存储器效应，特别是电存储器效应。 预失真器包括：用于补偿由放大器（3）引起的非线性失真的失真补偿电路（8），其中失真补偿电路输出要输入到放大器的预失真信号。 预失真器包括：连接在失真补偿电路和放大器之间的第一滤波器部分（21），用于补偿出现在包括放大器的整个模拟电路中的信号分量中出现的频率特性; 和连接在失真补偿电路和第一滤波器部分之间或第一滤波器部分和放大器之间的第二滤波器部分（22），用于补偿出现在放大器中出现的失真分量中的频率特性。

公开(公告)号：US20090317833A1

公开(公告)日：2009-12-24

申请号：US12225721

申请日：2007-03-29

申请人： Osamu Hazeki ,  Kaoru Hazeki ,  Masayuki Ii ,  Naoko Matsunaga

发明人： Osamu Hazeki ,  Kaoru Hazeki ,  Masayuki Ii ,  Naoko Matsunaga

IPC分类号： G01N33/53

CPC分类号： G01N33/566 ,  G01N2333/70596 ,  G01N2500/04 ,  G01N2500/10

摘要： The present invention provides a method of screening for a drug for the prophylaxis or treatment of at least one disease selected from the group consisting of cardiac disease, autoimmune disease, inflammatory disease, central nervous system disease, infectious disease, sepsis, severe sepsis and septic shock, which includes selecting a substance that binds to an intracellular region of TLR4, and inhibits signal transduction from said molecule, and a kit for this method, which contains (1) a cell that expresses wild-type TLR4 and (2) a cell that expresses a mutant TLR4, and which can detect a signal from TLR4 with expression of a reporter gene as an index.

摘要翻译： 本发明提供了一种筛选用于预防或治疗选自心脏病，自身免疫疾病，炎性疾病，中枢神经系统疾病，感染性疾病，败血症，严重败血症和败血症的至少一种疾病的药物的方法 其包括选择与TLR4的细胞内区域结合的物质，并抑制所述分子的信号转导，以及用于该方法的试剂盒，其包含（1）表达野生型TLR4的细胞和（2）细胞 其表达突变体TLR4，并且可以以报告基因的表达作为指标检测来自TLR4的信号。

公开(公告)号：US08559583B1

公开(公告)日：2013-10-15

申请号：US12394576

申请日：2009-02-27

申请人： Takashi Sato ,  Masanori Ino ,  Yasunobu Fujiki ,  Kazunori Hashimoto ,  Junichiro Otonari ,  Hisaki Sato ,  Naoko Matsunaga

发明人： Takashi Sato ,  Masanori Ino ,  Yasunobu Fujiki ,  Kazunori Hashimoto ,  Junichiro Otonari ,  Hisaki Sato ,  Naoko Matsunaga

IPC分类号： G21C9/00

CPC分类号： G21C9/004 ,  G21C1/086 ,  G21C15/18 ,  G21Y2002/304 ,  G21Y2004/30 ,  Y02E30/32

摘要： A passive cooling and depressurization system for a pressurized water nuclear plant is provided with a cooling water pool, a steam supply piping, a heat exchanger, a steam supply valve, a coolant return pipe and an outlet valve. The steam supply piping extends from the gas phase of the pressurizer. The heat exchanger exchanges heat between water stored in the cooling water pool and steam flowing through the steam supply piping. The steam supply valve is equipped on the steam supply piping. The coolant return pipe extends from the heat exchanger to a liquid phase of the reactor pressure boundary. The outlet valve is equipped on the coolant return pipe.

摘要翻译： 用于加压水核电厂的被动冷却和减压系统设置有冷却水池，蒸汽供应管道，热交换器，蒸汽供应阀，冷却剂回流管和出口阀。 蒸汽供应管道从加压器的气相延伸。 热交换器在存储在冷却水池中的水和通过蒸汽供应管道的蒸汽之间交换热量。 蒸汽供应阀配备在蒸汽供应管道上。 冷却剂回流管从热交换器延伸到反应堆压力边界的液相。 排气阀装在冷却液回流管上。

公开(公告)号：US20130259183A1

公开(公告)日：2013-10-03

申请号：US12394576

申请日：2009-02-27

申请人： Takashi Sato ,  Masanori Ino ,  Yasunobu Fujiki ,  Kazunori Hashimoto ,  Junichiro Otonari ,  Hisaki Sato ,  Naoko Matsunaga

发明人： Takashi Sato ,  Masanori Ino ,  Yasunobu Fujiki ,  Kazunori Hashimoto ,  Junichiro Otonari ,  Hisaki Sato ,  Naoko Matsunaga

IPC分类号： G21C9/004

CPC分类号： G21C9/004 ,  G21C1/086 ,  G21C15/18 ,  G21Y2002/304 ,  G21Y2004/30 ,  Y02E30/32

摘要： A passive cooling and depressurization system for a pressurized water nuclear plant is provided with a cooling water pool, a steam supply piping, a heat exchanger, a steam supply valve, a coolant return pipe and an outlet valve. The steam supply piping extends from the gas phase of the pressurizer. The heat exchanger exchanges heat between water stored in the cooling water pool and steam flowing through the steam supply piping. The steam supply valve is equipped on the steam supply piping. The coolant return pipe extends from the heat exchanger to a liquid phase of the reactor pressure boundary. The outlet valve is equipped on the coolant return pipe.

摘要翻译： 用于加压水核电厂的被动冷却和减压系统设置有冷却水池，蒸汽供应管道，热交换器，蒸汽供应阀，冷却剂回流管和出口阀。 蒸汽供应管道从加压器的气相延伸。 热交换器在存储在冷却水池中的水和通过蒸汽供应管道的蒸汽之间交换热量。 蒸汽供应阀配备在蒸汽供应管道上。 冷却剂回流管从热交换器延伸到反应堆压力边界的液相。 排气阀装在冷却液回流管上。

公开(公告)号：US08329420B2

公开(公告)日：2012-12-11

申请号：US12225721

申请日：2007-03-29

申请人： Osamu Hazeki ,  Kaoru Hazeki ,  Masayuki Ii ,  Naoko Matsunaga

发明人： Osamu Hazeki ,  Kaoru Hazeki ,  Masayuki Ii ,  Naoko Matsunaga

IPC分类号： G01N33/567 ,  C12N1/21 ,  C12N1/19 ,  C12N5/10 ,  C12N5/16 ,  C12N5/18 ,  C12N5/22 ,  C07K14/705

CPC分类号： G01N33/566 ,  G01N2333/70596 ,  G01N2500/04 ,  G01N2500/10

摘要： The present invention provides a method of screening for a drug for the prophylaxis or treatment of at least one disease selected from the group consisting of cardiac disease, autoimmune disease, inflammatory disease, central nervous system disease, infectious disease, sepsis, severe sepsis and septic shock, which includes selecting a substance that binds to an intracellular region of TLR4, and inhibits signal transduction from said molecule, and a kit for this method, which contains (1) a cell that expresses wild-type TLR4 and (2) a cell that expresses a mutant TLR4, and which can detect a signal from TLR4 with expression of a reporter gene as an index.

摘要翻译： 本发明提供了一种筛选用于预防或治疗选自心脏病，自身免疫疾病，炎性疾病，中枢神经系统疾病，感染性疾病，败血症，严重败血症和败血症的至少一种疾病的药物的方法 其包括选择与TLR4的细胞内区域结合的物质，并抑制所述分子的信号转导，以及用于该方法的试剂盒，其包含（1）表达野生型TLR4的细胞和（2）细胞 其表达突变体TLR4，并且可以以报告基因的表达作为指标检测来自TLR4的信号。