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53 条记录 (耗时 0.032 秒)

    Blood filter cartridge
    1.
    发明授权
    Blood filter cartridge 失效
    血液滤芯

    公开(公告)号：US06217540B1

    公开(公告)日：2001-04-17

    申请号：US09349173

    申请日：1999-07-09

    申请人： Kenichiro Yazawa ,  Keiichi Ishizaki ,  Takeshi Igarashi ,  Masao Kitajima ,  Shigeru Tezuka ,  Takaki Arai ,  Toshihisa Ito ,  Osamu Seshimoto

    发明人： Kenichiro Yazawa ,  Keiichi Ishizaki ,  Takeshi Igarashi ,  Masao Kitajima ,  Shigeru Tezuka ,  Takaki Arai ,  Toshihisa Ito ,  Osamu Seshimoto

    IPC分类号： A61M3700

    CPC分类号： G01N33/491

    摘要： The invention provides a blood filter cartridge which is made so that the filtrate discharged from the filtrate outlet is not drawn back to the inside of the filtering chamber. The blood filter cartridge includes a blood filtering material, a holder containing the blood filtering material and having a blood inlet and a filtrate outlet, and a filtrate receiver which receives the filtrate discharged from the filtrate outlet. The blood filter catridge is provided with a means for preventing the filtrate in the filtrate receiver from returning to inside of the holder upon finishing filtration. Such means include the following: removing opposite faces around the filtrate outlet, making length of lower end of the filtrate outlet 0.8 mm or more, smoothing surface around the filtrate outlet, and forming surface around the filtrate outlet by a material having a small surface energy.

    摘要翻译： 本发明提供了一种血液过滤器滤芯，其被制成使得从滤液出口排出的滤液不会被抽回到过滤室的内部。 血液过滤器滤芯包括血液过滤材料，含有血液过滤材料并具有血液入口和滤液出口的保持器和接收从滤​​液出口排出的滤液的滤液接收器。 血液过滤器夹具设置有用于防止滤液接收器中的滤液在完成过滤时返回到保持器内部的装置。 这样的方法包括以下步骤：除去滤液出口周围的相对面，使滤液出口的下端长度为0.8mm以上，使滤液出口周围的表面光滑，并且通过具有小表面能的材料在滤液出口周围形成表面 。

    Multilayer device for detecting bilurubin
    2.
    发明授权
    Multilayer device for detecting bilurubin 失效
    用于检测胆红素的多层装置

    公开(公告)号：US4877579A

    公开(公告)日：1989-10-31

    申请号：US198590

    申请日：1988-05-23

    申请人： Kenichiro Yazawa ,  Osamu Seshimoto ,  Masao Kitajima ,  Asaji Kondo

    发明人： Kenichiro Yazawa ,  Osamu Seshimoto ,  Masao Kitajima ,  Asaji Kondo

    IPC分类号： G01N31/22 ,  G01N33/72

    CPC分类号： G01N33/728 ,  Y10T436/146666 ,  Y10T436/255

    摘要： A method for quantitative determination of bilirubin is disclosed. The method comprises bringing a bilirubin-containing aqueous liquid sample into contact with a hydrophobic bilirubin extracting composition containing a hydrophobic amine capable of extracting bilirubin. The amine extracts the bilirubin in said aqueous liquid sample. Photometry is then used to determine the concentration of bilirubin extracted with the bilirubin extracting composition. A device for use in this method is also disclosed. The device has a layer containing a hydrophobic bilirubin extracting composition containing a hydrophobic amine capable of extracting bilirubin.

    摘要翻译： 公开了一种定量测定胆红素的方法。 该方法包括使含胆红素的含水液体样品与含有能够提取胆红素的疏水性胺的疏水性胆红素提取组合物接触。 胺提取所述含水液体样品中的胆红素。 然后使用光度测定法测定用胆红素提取组合物提取的胆红素的浓度。 还公开了一种用于该方法的装置。 该装置具有包含含有能够提取胆红素的疏水性胺的疏水性胆红素提取组合物的层。

    Method of bilirubin detection
    3.
    发明授权
    Method of bilirubin detection 失效
    胆红素检测方法

    公开(公告)号：US4612290A

    公开(公告)日：1986-09-16

    申请号：US542569

    申请日：1983-10-19

    申请人： Kenichiro Yazawa ,  Osamu Seshimoto ,  Masao Kitajima ,  Asaji Kondo

    发明人： Kenichiro Yazawa ,  Osamu Seshimoto ,  Masao Kitajima ,  Asaji Kondo

    IPC分类号： G01N31/22 ,  G01N33/72

    CPC分类号： G01N33/728 ,  Y10T436/146666 ,  Y10T436/255

    摘要： A method for quantitative determination of bilirubin is disclosed. The method comprises bringing a bilirubin-containing aqueous liquid sample into contact with a hydrophobic bilirubin extracting composition containing a hydrophobic amine capable of extracting bilirubin. The amine extracts the bilirubin in said aqueous liquid sample. Photometry is then used to determine the concentration of bilirubin extracted with the bilirubin extracting composition. A device for use in this method is also disclosed. The device has a layer containing a hydrophobic bilirubin extracting composition containing a hydrophobic amine capable of extracting bilirubin.

    摘要翻译： 公开了一种定量测定胆红素的方法。 该方法包括使含胆红素的含水液体样品与含有能够提取胆红素的疏水性胺的疏水性胆红素提取组合物接触。 胺提取所述含水液体样品中的胆红素。 然后使用光度测定法测定用胆红素提取组合物提取的胆红素的浓度。 还公开了一种用于该方法的装置。 该装置具有包含含有能够提取胆红素的疏水性胺的疏水性胆红素提取组合物的层。

    Blood filter unit
    4.
    发明授权
    Blood filter unit 失效
    血液过滤器单元

    公开(公告)号：US06170671B2

    公开(公告)日：2001-01-09

    申请号：US09290650

    申请日：1999-04-12

    申请人： Masao Kitajima ,  Kenichiro Yazawa ,  Shigeru Tezuka ,  Fumio Sugaya ,  Akemi Higo ,  Kiyotaka Fujiwara

    发明人： Masao Kitajima ,  Kenichiro Yazawa ,  Shigeru Tezuka ,  Fumio Sugaya ,  Akemi Higo ,  Kiyotaka Fujiwara

    IPC分类号： B01D2900

    CPC分类号： B01D39/2017 ,  B01D61/18 ,  B01D61/20 ,  B01D69/12 ,  G01N33/491

    摘要： The blood filter unit of the invention is composed of a blood filtering material made of glass fiber filter and microporous membrane and a holder having a blood inlet and a filtrate outlet. The holder accommodates the blood filtering material so that the microporous membrane is located on the filtrate outlet side, provides a space between the blood filtering material and the filtrate outlet, and provides a means for preventing adhesion of the blood filtering material on the filtrate outlet side. By using the blood filter unit, a necessary volume of plasma or serum for analysis can be separated surely, irrespective of hematocrit value of the blood.

    摘要翻译： 本发明的血液过滤器单元由玻璃纤维过滤器和微孔膜制成的血液过滤材料和具有血液入口和滤液出口的保持器构成。 保持器容纳血液过滤材料，使得微孔膜位于滤液出口侧，提供血液过滤材料和滤液出口之间的空间，并提供防止血液过滤材料在滤液出口侧粘附的手段 。 通过使用血液过滤器单元，可以确定地分离所需体积的血浆或血清，而不管血液的血细胞比容值如何。

    Device for determining ionic activity
    7.
    发明授权
    Device for determining ionic activity 失效
    用于测定离子活性的装置

    公开(公告)号：US4437970A

    公开(公告)日：1984-03-20

    申请号：US500600

    申请日：1983-06-02

    申请人： Masao Kitajima ,  Osamu Seshimoto ,  Kikuo Kubotera ,  Akira Yamaguchi

    发明人： Masao Kitajima ,  Osamu Seshimoto ,  Kikuo Kubotera ,  Akira Yamaguchi

    IPC分类号： G01N27/28 ,  G01N27/46 ,  G01N27/58

    CPC分类号： G01N27/307 ,  G01N27/3335

    摘要： A device for determining ionic activity composed of, as essential components, plural pairs of ion-selective solid electrodes each pair having two electrodes (one electrode on each of two sides) and each pair having a different ion-selective layer; two liquid distribution porous members, each member disposed over all the electrodes of each said side of the plural pairs; and a porous capillary bridge disposed on or between the liquid distribution porous members. The bridge can be in liquid contact with all the electrodes through the liquid distribution porous members and achieve electrical conduction between two electrodes in each pair after spotting a test solution and a reference solution. The device preferably further comprises a support frame and a cover having two apertures for liquid spotting. The device can simultaneously determine ionic activities of a plurality of different ions in a test solution, such as whole blood, plasma, serum, urine, etc., by spotting a test solution and a reference solution each in one operation and measuring an electrical potential difference of each pair.

    摘要翻译： 用于确定离子活性的装置，作为必要组分，每对具有两对电极（两侧各一个电极）和每对具有不同离子选择层的多对离子选择性固体电极， 两个液体分配多孔构件，每个构件设置在多对的每个所述侧的所有电极上; 以及布置在液体分配多孔构件之间或之间的多孔毛细管桥。 桥接器可以通过液体分配多孔构件与所有电极液体接触，并且在点样测试溶液和参考溶液之后实现每对中两个电极之间的导电。 该装置优选地还包括支撑框架和具有用于液体点样的两个孔的盖。 该装置可以通过在一个操作中分别检测测试溶液和参考溶液来测量测试溶液中的多种不同离子的离子活性，例如全血，血浆，血清，尿等，并测量电位 每对差异。

    Multilayered chemical analysis material for analysis of aqueous liquids
    8.
    发明授权
    Multilayered chemical analysis material for analysis of aqueous liquids 失效
    用于水性液体分析的多层化学分析材料

    公开(公告)号：US4732849A

    公开(公告)日：1988-03-22

    申请号：US828562

    申请日：1986-02-10

    申请人： Osamu Seshimoto ,  Masao Kitajima

    发明人： Osamu Seshimoto ,  Masao Kitajima

    IPC分类号： G01N31/22 ,  C12Q1/58 ,  G01N33/52 ,  G01N33/62

    CPC分类号： G01N33/525 ,  C12Q1/58 ,  Y10S435/805

    摘要： A multi-layered, chemical analysis material for analysis of an aqueous liquid, which comprises in one embodiment(a) a light-transmitting, water-impermeable support having provided thereon in sequence(b) a reagent layer and(c) a porous, sample-spreading layer, with(i) the reagent layer (b) containing a lake dye precursor dispersed in a hydrophilic binder,(ii) urease incorporated in the reagent layer (b) or in a layer adjacent the reagent layer (b), and(iii) a lake forming metal salt or lake forming metal oxide, which does not substantially inhibit the activity of urease, incorporated in the reagent layer (b) or in a layer adjacent the reagent layer (b) or a lake forming metal salt or oxide incorporated in a layer adjacent the reagent layer (b); and in a second embodiment the chemical analysis material includes(d) a radiation-blocking layer interposed between said reagent layer (b) and said porous, sample-spreading layer (c).

    摘要翻译： 一种用于分析水性液体的多层化学分析材料，其包括在一个实施方案中（a）在序列（b）中提供试剂层的透光性不透水性载体，（c）多孔， 样品扩散层，（i）包含分散在亲水性粘合剂中的色淀前体的试剂层（b），（ii）引入试剂层（b）中的脲酶或与试剂层（b）相邻的层中的脲酶， 并且（iii）形成金属盐或形成湖的金属氧化物的湖，其基本上不抑制尿素酶的活性，掺入试剂层（b）或试剂层（b）附近的层或形成湖的金属盐 或掺入与试剂层（b）相邻的层中的氧化物; 在第二实施方案中，化学分析材料包括（d）插入在所述试剂层（b）和所述多孔样品扩散层（c）之间的辐射阻挡层。

    Ion selective electrode and process of preparing the same
    9.
    发明授权
    Ion selective electrode and process of preparing the same 失效
    离子选择电极及其制备方法

    公开(公告)号：US4555274A

    公开(公告)日：1985-11-26

    申请号：US618285

    申请日：1984-06-07

    申请人： Masao Kitajima ,  Osamu Seshimoto ,  Shigemitsu Mizutani

    发明人： Masao Kitajima ,  Osamu Seshimoto ,  Shigemitsu Mizutani

    IPC分类号： G01N27/28 ,  G01N27/333 ,  C25F5/00

    CPC分类号： G01N27/3335

    摘要： An ion selective electrode comprising a support having provided thereon, in sequence, a conductive layer and an ion selective layer, which is characterized by having at least one groove through the conductive layer and covering the surface of the groove with the ion selective layer is disclosed. Half cells or electrodes useful for the measurement of ionic activity of chlorine, sodium, potassium or, carbonate or hydrogen carbonate ions in blood or other aqueous sample liquids can be prepared in an extremely simple manner. The single ion selective electrode element comprising paired ion selective electrodes in accordance with the present invention are electrochemically equivalent. A process for forming the same is also disclosed.

    摘要翻译： 公开了一种离子选择电极，其包括依次具有导电层和离子选择层的载体，其特征在于，具有通过导电层的至少一个沟槽和用离子选择层覆盖沟槽的表面 。 用于测量血液或其他含水样品液体中氯，钠，钾或碳酸氢根离子或碳酸氢根离子的离子活性的半电池或电极可以非常简单的方式制备。 根据本发明的包括成对离子选择性电极的单离子选择电极元件是电化学等效的。 还公开了其形成方法。

    Ion selective electrode and process of preparing the same
    10.
    发明授权
    Ion selective electrode and process of preparing the same 失效

    公开(公告)号：US4528085A

    公开(公告)日：1985-07-09

    申请号：US475672

    申请日：1983-03-15

    申请人： Masao Kitajima ,  Osamu Seshimoto ,  Shigemitsu Mizutani

    发明人： Masao Kitajima ,  Osamu Seshimoto ,  Shigemitsu Mizutani

    IPC分类号： G01N27/28 ,  G01N27/333 ,  G01N27/46

    CPC分类号： G01N27/3335

    摘要： An ion selective electrode comprising a support having provided thereon, in sequence, a conductive layer and an ion selective layer, which is characterized by having at least one groove through the conductive layer and covering the surface of the groove with the ion selective layer is disclosed. Half cells or electrodes useful for the measurement of ionic activity of chlorine, sodium, potassium or, carbonate or hydrogen carbonate ions in blood or other aqueous sample liquids can be prepared in an extremely simple manner. The single ion selective electrode element comprising paired ion selective electrodes in accordance with the present invention are electrochemically equivalent. A process for forming the same is also disclosed.