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公开(公告)号：US06838662B2
公开(公告)日：2005-01-04
申请号：US10693874
申请日：2003-10-28
CPC分类号： H01J49/4235
摘要： A mass spectrometer is disclosed comprising a mass filter for separating ions according to their mass to charge ratio. The mass filter comprises a plurality of electrodes wherein ions are radially confined within the mass filter by the application of AC or RF voltages to the electrodes. One or more transient DC voltages or one or more transient DC voltage waveforms are progressively applied to the electrodes so that ions having a certain mass to charge ratio are separated from other ions having different mass to charge ratios which remain radially confined within the mass filter.
摘要翻译： 公开了一种质谱仪，其包括用于根据其质荷比分离离子的质量过滤器。 质量过滤器包括多个电极，其中通过向电极施加AC或RF电压，离子径向地限制在质量过滤器内。 一个或多个瞬态直流电压或一个或多个瞬态直流电压波形逐渐地施加到电极，使得具有一定质荷比的离子与具有不同质量与电荷比的其它离子分离，这些离子保持径向地限制在质量过滤器内。
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公开(公告)号：US06914241B2
公开(公告)日：2005-07-05
申请号：US10868934
申请日：2004-06-17
CPC分类号： G01N27/622
摘要： A mass spectrometer comprising an ion mobility separator for separating ions according to their ion mobility is disclosed. The ion mobility separator comprises a plurality of electrodes and one or more transient DC voltages or one or more transient DC voltage waveforms are progressively applied to the electrodes so that ions having a certain ion mobility are separated from other ions having different ion mobilities.
摘要翻译： 公开了一种包括用于根据离子迁移率分离离子的离子迁移率分离器的质谱仪。 离子迁移率分离器包括多个电极和一个或多个瞬态DC电压或一个或多个瞬态DC电压波形逐渐施加到电极，使得具有一定离子迁移率的离子与具有不同离子迁移率的其它离子分离。
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公开(公告)号：US06791078B2
公开(公告)日：2004-09-14
申请号：US10603824
申请日：2003-06-26
IPC分类号： H01J4940
CPC分类号： G01N27/622
摘要： A mass spectrometer comprising an ion mobility separator for separating ions according to their ion mobility is disclosed. The ion mobility separator comprises a plurality of electrodes and one or more transient DC voltages or one or more transient DC voltage waveforms are progressively applied to the electrodes so that ions having a certain ion mobility are separated from other ions having different ion mobilities.
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公开(公告)号：US06884995B2
公开(公告)日：2005-04-26
申请号：US10610677
申请日：2003-07-02
CPC分类号： H01J49/005 , H01J49/062
摘要： A mass spectrometer is disclosed comprising a collision cell wherein ions having substantially different mass to charge ratios are arranged to be transmitted through at least a portion of the collision cell at substantially the same time and with substantially the same velocity preferably by means of one or more transient DC voltages or one or more transient DC voltage waveforms which are applied to the electrodes forming the collision cell so that ions are urged through the collision cell at a constant controlled velocity. By appropriate setting of the velocity of the DC voltage or DC voltage waveform passing along the length of the collision cell an efficient collision cell is provided which is able to fragment ions having considerably different mass to charge ratio at substantially the same time in an optimal manner.
摘要翻译： 公开了一种质谱仪，其包括碰撞池，其中具有基本上不同的质荷比的离子被布置成在基本相同的时间和基本上相同的速度下通过至少一部分的碰撞池传播通过一个或多个 瞬态DC电压或一个或多个瞬态DC电压波形，其被施加到形成碰撞电池的电极，使得离子以恒定的受控速度被迫穿过碰撞池。 通过适当设定沿着碰撞电池的长度通过的直流电压或直流电压波形的速度，提供了一种有效的碰撞电池，其能够以最佳方式在基本上相同的时间将具有相当不同质荷比的离子分解 。
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公开(公告)号：US07205538B2
公开(公告)日：2007-04-17
申请号：US11472278
申请日：2006-06-22
IPC分类号： H01J49/40
CPC分类号： H01J49/4225
摘要： A mass spectrometer is disclosed comprising an ion trap wherein ions which have been temporally separated according to their mass to charge ratio or ion mobility enter the ion trap. Once at least some of the ions have entered the ion trap, a plurality of ion trapping regions are created along the length of the ion trap in order to fractionate the ions. Alternatively, the ions may be received within one or more axial trapping regions which are translated along the ion trap with a velocity which is progressively reduced to zero.
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公开(公告)号：US07071467B2
公开(公告)日：2006-07-04
申请号：US10633702
申请日：2003-08-05
IPC分类号： H01J49/40
CPC分类号： H01J49/4225
摘要： A mass spectrometer is disclosed comprising an ion trap wherein ions which have been temporally separated according to their mass to charge ratio or ion mobility enter the ion trap. Once at least some of the ions have entered the ion trap, a plurality of ion trapping regions are created along the length of the ion trap in order to fractionate the ions. Alternatively, the ions may be received within one or more axial trapping regions which are translated along the ion trap with a velocity which is progressively reduced to zero.
摘要翻译： 公开了一种质谱仪，其包括离子阱，其中根据其质荷比或离子迁移率暂时分离的离子进入离子阱。 一旦至少一些离子已经进入离子阱，沿着离子阱的长度产生多个离子捕获区域，以分离离子。 或者，离子可以被接收在一个或多个沿着离子阱平移的轴向捕获区域中，其速度逐渐减小到零。
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公开(公告)号：US08895920B2
公开(公告)日：2014-11-25
申请号：US13702931
申请日：2011-06-07
申请人： Jeffery Mark Brown , Anthony James Gilbert , John Brian Hoyes , David J. Langridge , Jason Lee Wildgoose
发明人： Jeffery Mark Brown , Anthony James Gilbert , John Brian Hoyes , David J. Langridge , Jason Lee Wildgoose
CPC分类号： H01J49/401 , H01J49/0031 , H01J49/0095 , H01J49/062 , H01J49/067 , H01J49/405
摘要： A mass spectrometer is disclosed comprising a RF confinement device, a beam expander and a Time of Flight mass analyzer. The beam expander is arranged to expand an ion beam emerging from the RF confinement device so that the ion beam is expanded to a diameter of at least 3 mm in the orthogonal acceleration extraction region of the Time of Flight mass analyzer.
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公开(公告)号：US06992283B2
公开(公告)日：2006-01-31
申请号：US10739041
申请日：2003-12-19
IPC分类号： H01J49/00
CPC分类号： H01J49/40 , G01N27/622 , H01J49/0036 , H01J49/004
摘要： A mass spectrometer is disclosed wherein ions are passed through an ion mobility separator and are then mass analysed by a Time of Flight mass analyzer. Multiple sets of mass spectral data are obtained which are then post-processed so that mass spectral data relating to ions having undesired charge state(s) is filtered out. The resultant mass spectrum comprises ions having a desired charge state.
摘要翻译： 公开了一种质谱仪，其中离子通过离子迁移率分离器，然后通过飞行时间质量分析仪进行质量分析。 获得多组质谱数据，然后对其进行后处理，从而滤出与具有不期望的电荷状态的离子相关的质谱数据。 所得质谱包括具有所需电荷状态的离子。
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公开(公告)号：US09214328B2
公开(公告)日：2015-12-15
申请号：US13996893
申请日：2011-12-22
IPC分类号： H01J49/40
CPC分类号： H01J49/403 , H01J49/0027 , H01J49/401
摘要： A Time of Flight mass spectrometer is disclosed wherein a fifth order spatial focusing device is provided. The device which may comprise an additional stage in the source region of the Time of Flight mass analyzer is arranged to introduce a non-zero fifth order spatial focusing term so that the combined effect of first, third and fifth order spatial focusing terms results in a reduction in the spread of ion arrival times ΔT of ions arriving at the ion detector.
摘要翻译： 公开了一种提供五阶空间聚焦装置的飞行时间质谱仪。 可以在飞行时间质量分析器的源区域中包括附加级的装置被布置成引入非零五阶空间聚焦项，使得第一，第三和第五阶空间聚焦项的组合效应导致 减少到达离子检测器的离子到达时间和离子浓度Dgr。
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10.发明授权Electrostatic gimbal for correction of errors in time of flight mass spectrometers 有权用于校正飞行时间质谱仪误差的静电万向架公开(公告)号：US08921775B2
公开(公告)日：2014-12-30
申请号：US14004946
申请日：2012-03-13
CPC分类号： H01J49/403 , H01J49/40
摘要： A Time of Flight mass analyser is disclosed comprising one or more devices arranged and adapted to correct for tilt in an isochronous plane of ions and to adjust the isochronous plane of the ions so as to be parallel with the plane of detection in an ion detector.
摘要翻译： 公开了一种飞行时间质量分析器，其包括一个或多个设备，其被配置并适于校正离子的等时平面中的倾斜，并且在离子检测器中调整离子的等时平面以与检测平面平行。
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