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    Space focus time of flight mass spectrometer
    2.
    发明授权
    Space focus time of flight mass spectrometer 有权
    空间聚焦时间飞行质谱仪

    公开(公告)号：US09214328B2

    公开(公告)日：2015-12-15

    申请号：US13996893

    申请日：2011-12-22

    申请人： John Brian Hoyes ,  David J. Langridge ,  Jason Lee Wildgoose

    发明人： John Brian Hoyes ,  David J. Langridge ,  Jason Lee Wildgoose

    IPC分类号： H01J49/40

    CPC分类号： H01J49/403 ,  H01J49/0027 ,  H01J49/401

    摘要： A Time of Flight mass spectrometer is disclosed wherein a fifth order spatial focusing device is provided. The device which may comprise an additional stage in the source region of the Time of Flight mass analyzer is arranged to introduce a non-zero fifth order spatial focusing term so that the combined effect of first, third and fifth order spatial focusing terms results in a reduction in the spread of ion arrival times ΔT of ions arriving at the ion detector.

    摘要翻译： 公开了一种提供五阶空间聚焦装置的飞行时间质谱仪。 可以在飞行时间质量分析器的源区域中包括附加级的装置被布置成引入非零五阶空间聚焦项，使得第一，第三和第五阶空间聚焦项的组合效应导致 减少到达离子检测器的离子到达时间和离子浓度Dgr。

    Space Focus Time of Flight Mass Spectrometer
    4.
    发明申请
    Space Focus Time of Flight Mass Spectrometer 有权
    空间聚焦时间飞行质谱仪

    公开(公告)号：US20140014830A1

    公开(公告)日：2014-01-16

    申请号：US13996893

    申请日：2011-12-22

    申请人： John Brian Hoyes ,  David J. Langridge ,  Jason Lee Wildgoose

    发明人： John Brian Hoyes ,  David J. Langridge ,  Jason Lee Wildgoose

    IPC分类号： H01J49/40

    CPC分类号： H01J49/403 ,  H01J49/0027 ,  H01J49/401

    摘要： A Time of Flight mass spectrometer is disclosed wherein a fifth order spatial focusing device is provided. The device which may comprise an additional stage in the source region of the Time of Flight mass analyser is arranged to introduce a non-zero fifth order spatial focusing term so that the combined effect of first, third and fifth order spatial focusing terms results in a reduction in the spread of ion arrival times ΔT of ions arriving at the ion detector.

    摘要翻译： 公开了一种提供五阶空间聚焦装置的飞行时间质谱仪。 可以在飞行时间质量分析器的源区域中包括附加级的装置被布置成引入非零五阶空间聚焦项，使得第一，第三和第五阶空间聚焦项的组合效应导致 降低到达离子检测器的离子到达时间ΔT的离子扩散。

    Ion mobility separator with variable effective length
    7.
    发明授权
    Ion mobility separator with variable effective length 有权
    具有可变有效长度的离子迁移分离器

    公开(公告)号：US08829433B2

    公开(公告)日：2014-09-09

    申请号：US14004486

    申请日：2012-03-13

    申请人： Martin Raymond Green ,  David J. Langridge ,  Jason Lee Wildgoose

    发明人： Martin Raymond Green ,  David J. Langridge ,  Jason Lee Wildgoose

    IPC分类号： B01D59/44 ,  H01J49/36

    CPC分类号： H01J49/36 ,  G01N27/624 ,  H01J49/06 ,  H01J49/42 ,  H01J49/426

    摘要： An ion mobility separator or spectrometer is disclosed comprising an inner cylinder and an outer cylinder defining an annular volume through which ions are transmitted. Spiral electrodes a-f are arranged on a surface of the inner cylinder and/or on a surface of the outer cylinder. A first device is arranged and adapted to maintain a DC electric field or a pseudo-potential force which acts to urge ions from a first end of the ion mobility separator or spectrometer to a second end of the ion mobility separator or spectrometer. A second device is arranged and adapted to apply one or more transient DC voltages to the spiral electrodes in order to urge ions towards the first end of the ion mobility separator or spectrometer. The net effect is to extend the effective path length of the ion mobility separator.

    摘要翻译： 公开了一种离子迁移率分离器或光谱仪，其包括限定通过离子传播的环形体积的内圆筒和外圆筒。 螺旋电极a-f布置在内筒的表面上和/或外筒的表面上。 第一装置被布置并适于维持DC电场或伪电势力，其作用是将离子从离子迁移率分离器或光谱仪的第一端推到离子迁移率分离器或光谱仪的第二端。 第二装置被布置并适于将一个或多个瞬态DC电压施加到螺旋电极，以促使离子朝向离子迁移分离器或光谱仪的第一端。 净效应是延长离子迁移率分离器的有效路径长度。

    Segmented planar calibration for correction of errors in time of flight mass spectrometers
    8.
    发明授权
    Segmented planar calibration for correction of errors in time of flight mass spectrometers 有权
    分段平面校准用于校正飞行时间质谱仪中的误差

    公开(公告)号：US08872104B2

    公开(公告)日：2014-10-28

    申请号：US14117756

    申请日：2012-05-16

    申请人： David J. Langridge ,  Jason Lee Wildgoose

    发明人： David J. Langridge ,  Jason Lee Wildgoose

    IPC分类号： B01D59/44 ,  H01J49/00 ,  H01J49/02

    CPC分类号： H01J49/0036 ,  H01J49/0009 ,  H01J49/02 ,  H01J49/025 ,  H01J49/40 ,  H01J49/401

    摘要： An ion detector system for a mass spectrometer is disclosed comprising an ion detector comprising an array of detector elements. The ion detector system is arranged to correct for tilt and non-linear aberrations in an isochronous plane of ions. The ion detector system generates separate first mass spectral data sets for each detector element and then applies a calibration coefficient to each of the first mass spectral data sets to produce a plurality of second calibrated mass spectral data sets. The plurality of second calibrated mass spectral data sets are then combined to form a composite mass spectral data set.

    摘要翻译： 公开了一种用于质谱仪的离子检测器系统，其包括具有检测器元件阵列的离子检测器。 离子检测器系统被布置成校正离子的等时平面中的倾斜和非线性像差。 离子检测器系统为每个检测器元件生成单独的第一质谱数据集，然后将校准系数应用于每个第一质谱数据集以产生多个第二校准质谱数据集。 然后将多个第二校准质谱数据组合以形成复合质谱数据集。

    DC ion guide for analytical filtering/separation
    9.
    发明授权
    DC ion guide for analytical filtering/separation 有权
    用于分析过滤/分离的直流离子导向器

    公开(公告)号：US09111654B2

    公开(公告)日：2015-08-18

    申请号：US14003487

    申请日：2012-03-07

    申请人： Kevin Giles ,  Martin Raymond Green ,  Daniel James Kenny ,  David J. Langridge ,  Jason Lee Wildgoose

    发明人： Kevin Giles ,  Martin Raymond Green ,  Daniel James Kenny ,  David J. Langridge ,  Jason Lee Wildgoose

    IPC分类号： H01J49/26 ,  G21K1/00 ,  H01J49/42 ,  H01J49/28

    CPC分类号： G21K1/00 ,  H01J49/062 ,  H01J49/28 ,  H01J49/427

    摘要： An ion guide is disclosed comprising a plurality of electrodes. A first device is arranged and adapted to apply a RF voltage to at least some of the electrodes in order to form, in use, a pseudo-potential well which acts to confine ions in a first direction within the ion guide. A second device is arranged and adapted to apply a DC voltage to at least some of the electrodes in order to form, in use, a DC potential well which acts to confine ions in a second direction within the ion guide. A third device is arranged and adapted to cause ions having desired or undesired mass to charge ratios to be mass to charge ratio selectively ejected from the ion guide in the second direction.

    摘要翻译： 公开了一种离子导向器，其包括多个电极。 第一装置被布置并适于将RF电压施加到至少一些电极，以在使用中形成用于将离子限制在离子导向器内的第一方向上的伪电位阱。 第二装置被布置并适于将DC电压施加到至少一些电极，以在使用中形成用于在离子导向器内沿第二方向限制离子的DC势阱。 第三装置被布置并适于使具有期望或不需要的质量的充电比例的离子成为从第二方向从离子导向器选择性地喷射的质荷比。

    Ion Trap With Spatially Extended Ion Trapping Region
    10.
    发明申请
    Ion Trap With Spatially Extended Ion Trapping Region 有权
    离子阱与空间扩展的离子捕获区域

    公开(公告)号：US20140299761A1

    公开(公告)日：2014-10-09

    申请号：US14240667

    申请日：2012-08-22

    申请人： Kevin Giles ,  Martin Raymond Green ,  Daniel James Kenny ,  David J. Langridge ,  Jason Lee Wildgoose

    发明人： Kevin Giles ,  Martin Raymond Green ,  Daniel James Kenny ,  David J. Langridge ,  Jason Lee Wildgoose

    IPC分类号： H01J49/42

    CPC分类号： H01J49/424 ,  H01J49/421 ,  H01J49/422 ,  H01J49/4285

    摘要： A mass or mass to charge ratio selective ion trap is disclosed having an increased charge storage capacity. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC voltage and/or an RF voltage acts to confine ions in a second (x) direction within the ion trap. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. Ions are excited in the third (z) direction and are caused to be mass or mass to charge ratio selectively ejected in the third (z) direction.

    摘要翻译： 公开了具有增加的电荷存储容量的质量或质量 - 电荷比选择性离子阱。 RF电压用于将离子限制在离子阱内的第一（y）方向。 DC电压和/或RF电压用于将离子限制在离子阱内的第二（x）方向。 二次直流势阱用于将离子限制在离子阱内的第三（z）方向。 离子在第三（z）方向上被激发，并且被导致在第三（z）方向上选择性地喷射的质量或质量 - 充电比。