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    EXPANDABLE THERMALLY-STABLE STYRENE COPOLYMERS
    2.
    发明申请
    EXPANDABLE THERMALLY-STABLE STYRENE COPOLYMERS 审中-公开
    可膨胀的热稳定苯乙烯共聚物

    公开(公告)号：US20130059933A1

    公开(公告)日：2013-03-07

    申请号：US13599528

    申请日：2012-08-30

    申请人： Holger Ruckdäschel ,  Alexandre Terrenoire ,  Jan Kurt Walter Sandler ,  Klaus Hahn ,  Ingo Bellin ,  Georg Grässel ,  Martin Weber

    发明人： Holger Ruckdäschel ,  Alexandre Terrenoire ,  Jan Kurt Walter Sandler ,  Klaus Hahn ,  Ingo Bellin ,  Georg Grässel ,  Martin Weber

    IPC分类号： C08J9/18 ,  C08L25/08

    CPC分类号： C08L25/12 ,  C08J9/0061 ,  C08J9/16 ,  C08J2201/03 ,  C08J2325/04 ,  C08J2425/04 ,  C08L35/06

    摘要： A process for producing an expandable pelletized polymeric material which comprises: a) providing a polymer component, consisting of a styrene polymer component having a glass transition temperature of ≧130° C., formed from and one or more thermoplastic polymers selected from the group consisting of aromatic polyethers; polyolefins; polyacrylates; polycarbonates; polyesters; polyamides; polyether sulfones; polyether ketones and polyether sulfides, (b) heating the polymer component to form a polymer melt, (c) introducing a blowing agent component into the polymer melt to form a foamable melt, (d) homogenizing the mixture, (f) extruding the blowing agent-containing polymer melt through a die plate, (g) pelletizing the blowing agent-containing melt in a liquid-filled chamber to form a pelletized material. The expandable pelletized material is suitable for production of molded foam bodies, the applications as insulation material and as structural foam elements for lightweight construction and composite applications.

    摘要翻译： 一种用于生产可膨胀的颗粒状聚合物材料的方法，其包括：a）提供由玻璃化转变温度为130℃的玻璃化转变温度的苯乙烯聚合物组分组成的聚合物组分，由一种或多种选自以下的热塑性聚合物形成： 的芳族聚醚; 聚烯烃; 聚丙烯酸酯; 聚碳酸酯; 聚酯; 聚酰胺 聚醚砜; 聚醚酮和聚醚硫醚，（b）加热聚合物组分以形成聚合物熔体，（c）将引发剂组分引入聚合物熔体中以形成可发泡的熔体，（d）使混合物均质化，（f） 含聚合物的聚合物通过模板熔融，（g）在充满液体的室中造粒含发泡剂的熔体以形成造粒材料。 可膨胀颗粒材料适用于生产模制泡沫体，应用作为绝缘材料和用于轻型结构和复合应用的结构泡沫元件。

    Nanoporous foamed active compound-containing preparations based on pharmaceutically acceptable thermoplastically workable polymers
    3.
    发明授权
    Nanoporous foamed active compound-containing preparations based on pharmaceutically acceptable thermoplastically workable polymers 失效
    基于药学上可接受的热塑性可加工聚合物的纳米多孔泡沫活性成分制剂

    公开(公告)号：US08636929B2

    公开(公告)日：2014-01-28

    申请号：US13111999

    申请日：2011-05-20

    申请人： Jan Kurt Walter Sandler ,  Ingo Bellin ,  Dejan Djuric ,  Karl Kolter ,  Holger Ruckdäschel

    发明人： Jan Kurt Walter Sandler ,  Ingo Bellin ,  Dejan Djuric ,  Karl Kolter ,  Holger Ruckdäschel

    IPC分类号： B29C67/20

    CPC分类号： A61K31/235 ,  A61K9/146 ,  A61K31/496 ,  B82Y5/00

    摘要： Process for the production of nanoporous foamed active substance-containing preparations, wherein the active substance is present embedded in a pharmaceutically acceptable polymer, wherein, in stage a) loading of a polymeric molding composition or a polymer melt with a propellant is effected at a pressure and at a temperature at which the propellant is in the supercritical state, in stage b) heating of the laden polymer molding compound or melt is carried out under pressure at a temperature which lies in the range from −40 to +60° C., preferably −20 to +55° C., and especially preferably 0 to +50° C. around the glass transition temperature of the unladen (prior to loading) polymeric molding compound and in stage c) a depressurization of the polymeric molding compound or melt laden in stage a) and heated under pressure in stage b) is effected out with a depressurization rate in the range from 15,000 to 200,000 MPa/sec.

    摘要翻译： 制备纳米多孔泡沫活性物质制剂的方法，其中活性物质包含在药学上可接受的聚合物中，其中在阶段a）聚合物模塑组合物或聚合物熔体与推进剂的加载在压力 并且在推进剂处于超临界状态的温度下，在阶段b）加载聚合物模塑料或熔体在加压下在-40至+ 60℃的温度下进行， 优选为-20至+ 55℃，特别优选为0至+ 50℃，并且在阶段c）将聚合物模塑料或熔体的减压 在步骤a）中负载并且在阶段b）中加压，以15,000至200,000MPa /秒的减压速率进行。

    Nanoporous Foamed Active Compound-Containing Preparations Based On Pharmaceutically Acceptable Thermoplastically Workable Polymers
    5.
    发明申请
    Nanoporous Foamed Active Compound-Containing Preparations Based On Pharmaceutically Acceptable Thermoplastically Workable Polymers 失效
    基于药学上可接受的热塑性可加工聚合物的纳米发泡活性化合物制剂

    公开(公告)号：US20110287066A1

    公开(公告)日：2011-11-24

    申请号：US13111999

    申请日：2011-05-20

    申请人： Jan Kurt Walter Sandler ,  Ingo Bellin ,  Dejan Djuric ,  Karl Kolter ,  Holger Ruckdäschel

    发明人： Jan Kurt Walter Sandler ,  Ingo Bellin ,  Dejan Djuric ,  Karl Kolter ,  Holger Ruckdäschel

    IPC分类号： A61K9/00 ,  A61K31/235 ,  A61P9/12 ,  A61P31/00 ,  A61K31/496 ,  A61P3/06 ,  B82Y5/00

    CPC分类号： A61K31/235 ,  A61K9/146 ,  A61K31/496 ,  B82Y5/00

    摘要： Process for the production of nanoporous foamed active substance-containing preparations, wherein the active substance is present embedded in a pharmaceutically acceptable polymer, wherein, in stage a) loading of a polymeric molding composition or a polymer melt with a propellant is effected at a pressure and at a temperature at which the propellant is in the supercritical state, in stage b) heating of the laden polymer molding compound or melt is carried out under pressure at a temperature which lies in the range from −40 to +60° C., preferably −20 to +55° C., and especially preferably 0 to +50° C. around the glass transition temperature of the unladen (prior to loading) polymeric molding compound and in stage c) a depressurization of the polymeric molding compound or melt laden in stage a) and heated under pressure in stage b) is effected out with a depressurization rate in the range from 15,000 to 200,000 MPa/sec.

    摘要翻译： 制备纳米多孔泡沫活性物质制剂的方法，其中活性物质包含在药学上可接受的聚合物中，其中在阶段a）聚合物模塑组合物或聚合物熔体与推进剂的加载在压力 并且在推进剂处于超临界状态的温度下，在阶段b）加载聚合物模塑料或熔体在加压下在-40至+ 60℃的温度下进行， 优选为-20至+ 55℃，特别优选为0至+ 50℃，并且在阶段c）将聚合物模塑料或熔体的减压 在步骤a）中负载并且在阶段b）中加压，以15,000至200,000MPa /秒的减压速率进行。

    EXTRUDED SAN FOAMS
    6.
    发明申请
    EXTRUDED SAN FOAMS 审中-公开

    公开(公告)号：US20120161061A1

    公开(公告)日：2012-06-28

    申请号：US13394477

    申请日：2010-09-06

    申请人： Klaus Hahn ,  Holger Ruckdäschel ,  Ingo Bellin ,  Peter Merkel ,  Markus Hartenstein

    发明人： Klaus Hahn ,  Holger Ruckdäschel ,  Ingo Bellin ,  Peter Merkel ,  Markus Hartenstein

    IPC分类号： C08J9/08 ,  C08L33/20 ,  E04B1/74 ,  C08F220/44

    CPC分类号： C08J9/127 ,  C08J2201/03 ,  C08J2205/052 ,  C08J2325/12

    摘要： Closed-cell extruded foam extruded foam with density in the range from 20 to 150 g/l and with a cell number in the range from 1 to 30 cells per mm is obtainable via (a) heating of a polymer component P, formed from P1) from 80 to 100% by weight (based on P) of one or more styrene-acrylonitrile copolymers (SAN), comprising a1) from 18 to 40% by weight (based on SAN) of copolymerized acrylonitrile, a2) from 60 to 82% by weight (based on SAN) of copolymerized styrene, and a3) from 0 to 22% by weight (based on SAN) of at least one copolymerized monomer from the group consisting of alkyl(meth)acrylates, (meth)acrylic acid, maleic anhydride and maleimides, P2) from 0 to 20% by weight (based on P) of one or more thermoplastic polymers from the group consisting of styrene copolymers, polyolefins, polyacrylates, polycarbonates (PC), polyesters, polyamides, polyether sulfones (PES), polyether ketones (PEK), and polyether sulfides, to form a polymer melt, (b) introduction of from 1 to 12% by weight (based on P) of a blowing agent component (T), which comprises less than 0.2% by weight of water (based on P), comprising b1) from 15 to 95% by weight (based on T) of carbon dioxide and b2) from 5 to 85% by weight (based on T) of one or more co-blowing agents selected from the group consisting of C1-C4 alcohols and C1-C4 carbonyl compounds, into the polymer melt to form a foamable melt, (c) extrusion of the foamable melt into a region of relatively low pressure, with foaming to give the extruded foam, (d) if appropriate, addition of additives to the polymer component (P) in at least

    摘要翻译： 通过（a）加热由P1形成的聚合物组分P，可获得密度为20至150g / l，细胞数范围为1至30个细胞/ mm的闭孔挤出泡沫挤出泡沫体 ）80至100重量％（基于P）一种或多种苯乙烯 - 丙烯腈共聚物（SAN），其包含a1）18至40重量％（基于SAN）共聚丙烯腈，a2）60至82 共聚苯乙烯的重量％（基于SAN），和a3）0至22重量％（基于SAN）的至少一种由（甲基）丙烯酸烷基酯，（甲基）丙烯酸烷基酯，（甲基）丙烯酸烷基酯， 马来酸酐和马来酰亚胺，P2）0至20重量％（基于P）来自苯乙烯共聚物，聚烯烃，聚丙烯酸酯，聚碳酸酯（PC），聚酯，聚酰胺，聚醚砜（PES）的一种或多种热塑性聚合物 ），聚醚酮（PEK）和聚醚硫化物，以形成聚合物熔体，（b）引入1至12％重量 h（基于P）发泡剂组分（T），其包含小于0.2重量％的水（基于P），其包含b1）15至95重量％（基于T）的二氧化碳和 b2）5至85重量％（基于T）一种或多种选自C1-C4醇和C1-C4羰基化合物的共发泡剂，进入聚合物熔体以形成可发泡的熔体（ c）将可发泡的熔体挤出到相对较低压力的区域中，发泡以得到挤出的泡沫，（d）如果合适，至少在聚合物组分（P）中加入添加剂