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    FILLER FOR AFFINITY CHROMATOGRAPHY
    2.
    发明申请
    FILLER FOR AFFINITY CHROMATOGRAPHY 有权
    填充色谱法

    公开(公告)号：US20130085199A1

    公开(公告)日：2013-04-04

    申请号：US13638751

    申请日：2011-03-29

    申请人： Kouji Tamori ,  Takayoshi Abe ,  Yusuke Okano ,  Masaki Momiyama ,  Hiroshi Kawai ,  Satoshi Hyugaji ,  Tomonori Shiotani ,  Kazuhiro Ikkyu ,  Yong Wang

    发明人： Kouji Tamori ,  Takayoshi Abe ,  Yusuke Okano ,  Masaki Momiyama ,  Hiroshi Kawai ,  Satoshi Hyugaji ,  Tomonori Shiotani ,  Kazuhiro Ikkyu ,  Yong Wang

    IPC分类号： C08F220/00 ,  C07K1/22 ,  C08F8/00

    CPC分类号： B01D15/3804 ,  B01J20/265 ,  B01J20/286 ,  C08F8/00 ,  C08F220/26 ,  Y10T428/2982

    摘要： Provided is a filler for affinity chromatography having a high dynamic binding capacity for proteins and having excellent alkali resistance and storage stability. The filler for affinity chromatography of the present invention comprises a porous particle consisting of a copolymer of 40 parts to 99.5 parts by mass of (M-1) a methacryloyl group-containing vinyl monomer that contains a hydroxyl group and does not contain an epoxy group, 0.5 parts to 30 parts by mass of (M-2) an epoxy group-containing vinyl monomer, 0 parts to 59.5 parts by mass of (M-3) a methacryloyl group-containing vinyl monomer which is other than the monomers (M-1) and (M-2), and 0 parts to 25 parts by mass of (M-4) a vinyl monomer other than the monomers (M-1), (M-2) and (M-3) (with the proviso that the total amount of the contents of (M-1), (M-2), (M-3) and (M-4) is 100 parts by mass); ring-opened epoxy group obtainable by ring-opening of epoxy group that is contained in the copolymer; and ligand that is bound to the porous particle.

    摘要翻译： 本发明提供一种对蛋白质具有高动态结合能力并具有优异的耐碱性和储存稳定性的亲和层析用填料。 本发明的亲和层析用填料包含由40〜99.5质量份的含有甲基丙烯酰基的含有甲基丙烯酰基的乙烯基单体（不含有环氧基）的（M-1）共聚物构成的多孔质粒子 ，（M-2）含有环氧基的乙烯基单体0.5〜30质量份，除了单体（M）以外的（M-3）含有甲基丙烯酰基的乙烯基单体的（M-3） -1）和（M-2）和0〜25质量份（M-4）除了单体（M-1），（M-2）和（M-3） 条件是（M-1），（M-2），（M-3）和（M-4）的含量的总量为100质量份） 通过共聚物中包含的环氧基开环获得的开环环氧基; 和与多孔颗粒结合的配体。

    Filler for affinity chromatography
    3.
    发明授权
    Filler for affinity chromatography 有权
    填料用于亲和层析

    公开(公告)号：US09162161B2

    公开(公告)日：2015-10-20

    申请号：US13638751

    申请日：2011-03-29

    申请人： Kouji Tamori ,  Takayoshi Abe ,  Yusuke Okano ,  Masaki Momiyama ,  Hiroshi Kawai ,  Satoshi Hyugaji ,  Tomonori Shiotani ,  Kazuhiro Ikkyu ,  Yong Wang

    发明人： Kouji Tamori ,  Takayoshi Abe ,  Yusuke Okano ,  Masaki Momiyama ,  Hiroshi Kawai ,  Satoshi Hyugaji ,  Tomonori Shiotani ,  Kazuhiro Ikkyu ,  Yong Wang

    IPC分类号： B01D15/04 ,  B01D15/08 ,  B01D15/38 ,  C08F8/00 ,  C08F220/26 ,  B01J20/26 ,  B01J20/286

    CPC分类号： B01D15/3804 ,  B01J20/265 ,  B01J20/286 ,  C08F8/00 ,  C08F220/26 ,  Y10T428/2982

    摘要： Provided is a filler for affinity chromatography having a high dynamic binding capacity for proteins and having excellent alkali resistance and storage stability. The filler for affinity chromatography of the present invention comprises a porous particle consisting of a copolymer of 40 parts to 99.5 parts by mass of (M-1) a methacryloyl group-containing vinyl monomer that contains a hydroxyl group and does not contain an epoxy group, 0.5 parts to 30 parts by mass of (M-2) an epoxy group-containing vinyl monomer, 0 parts to 59.5 parts by mass of (M-3) a methacryloyl group-containing vinyl monomer which is other than the monomers (M-1) and (M-2), and 0 parts to 25 parts by mass of (M-4) a vinyl monomer other than the monomers (M-1), (M-2) and (M-3) (with the proviso that the total amount of the contents of (M-1), (M-2), (M-3) and (M-4) is 100 parts by mass); ring-opened epoxy group obtainable by ring-opening of epoxy group that is contained in the copolymer; and ligand that is bound to the porous particle.

    摘要翻译： 本发明提供一种对蛋白质具有高动态结合能力并具有优异的耐碱性和储存稳定性的亲和层析用填料。 本发明的亲和层析用填料包含由40〜99.5质量份的含有甲基丙烯酰基的含有甲基丙烯酰基的乙烯基单体（不含有环氧基）的（M-1）共聚物构成的多孔质粒子 ，（M-2）含有环氧基的乙烯基单体0.5〜30质量份，除了单体（M）以外的（M-3）含有甲基丙烯酰基的乙烯基单体的（M-3） -1）和（M-2）和0〜25质量份（M-4）除了单体（M-1），（M-2）和（M-3） 条件是（M-1），（M-2），（M-3）和（M-4）的含量的总量为100质量份） 通过共聚物中包含的环氧基开环获得的开环环氧基; 和与多孔颗粒结合的配体。

    Method for pattern formation and resin composition for use in the method
    9.
    发明授权
    Method for pattern formation and resin composition for use in the method 有权
    用于图案形成的方法和用于该方法的树脂组合物

    公开(公告)号：US08211624B2

    公开(公告)日：2012-07-03

    申请号：US12601011

    申请日：2008-05-21

    申请人： Atsushi Nakamura ,  Tsutomu Shimokawa ,  Junichi Takahashi ,  Takayoshi Abe ,  Tomoki Nagai ,  Tomohiro Kakizawa

    发明人： Atsushi Nakamura ,  Tsutomu Shimokawa ,  Junichi Takahashi ,  Takayoshi Abe ,  Tomoki Nagai ,  Tomohiro Kakizawa

    IPC分类号： G03F7/00 ,  G03F7/004 ,  G03F7/20 ,  G03F7/26 ,  G03F7/40

    CPC分类号： G03F7/0392 ,  G03F7/0035 ,  G03F7/0397 ,  G03F7/40 ,  H01L21/0273 ,  Y10S430/106

    摘要： A pattern forming method includes (1) selectively exposing a first resist layer, and developing the exposed first resist layer to form a first pattern, (2) applying a resin composition containing a hydroxyl group-containing resin and a solvent to the first pattern, baking the applied resin composition, and developing the baked resin composition to form a second pattern, the hydroxyl group-containing resin becoming insoluble or scarcely soluble in a developer when baked, and (3) totally or selectively exposing the second pattern to make the second pattern partly soluble in the developer, and developing the exposed second pattern to form a third pattern in which at least a hole or a groove is formed in the second pattern.

    摘要翻译： 图案形成方法包括：（1）选择性地暴露第一抗蚀剂层，以及使曝光的第一抗蚀剂层显影以形成第一图案;（2）将含有羟基的树脂和溶剂的树脂组合物施加到第一图案， 烘烤所施加的树脂组合物，并显影所述烘焙的树脂组合物以形成第二图案，所述含羟基的树脂在烘烤时变得不溶或几乎不溶于显影剂，以及（3）全部或选择性地暴露所述第二图案以制备第二图案 图案部分地溶解在显影剂中，并且显影第二图案以形成第三图案，其中至少在第二图案中形成孔或凹槽。

    RESIN COMPOSITION FOR MICROPATTERN FORMATION AND METHOD OF MICROPATTERN FORMATION
    10.
    发明申请
    RESIN COMPOSITION FOR MICROPATTERN FORMATION AND METHOD OF MICROPATTERN FORMATION 审中-公开
    微生物形成的树脂组合物和微生物形成方法

    公开(公告)号：US20100009292A1

    公开(公告)日：2010-01-14

    申请号：US12525816

    申请日：2008-02-20

    申请人： Tomoki Nagai ,  Atsushi Nakamura ,  Takayoshi Abe ,  Makoto Sugiura

    发明人： Tomoki Nagai ,  Atsushi Nakamura ,  Takayoshi Abe ,  Makoto Sugiura

    IPC分类号： G03F7/20 ,  G03F7/039

    CPC分类号： G03F7/40

    摘要： A resin composition which can increase the pattern shrink rate while maintaining the advantages of capability of effectually and precisely micronizing the resist pattern gaps irrespective of the surface conditions of the substrate and forming resist patterns exceeding the wavelength limit economically at low cost in a good condition having only small defects, and a method of efficiently forming a micropattern using the resin composition are disclosed. The resin composition for forming a micropattern includes a hydroxyl group-containing resin, a crosslinking component, and an alcohol solvent which contains an alcohol and not more than 10 mass % of water relative to the total solvent. The crosslinking component includes a compound having two or more acryloyloxy groups in the molecule.

    摘要翻译： 可以提高图案收缩率的树脂组合物，同时保持有效地和精确地微细化抗蚀剂图案间隙的能力的优点，而不管基材的表面条件如何，并且在良好的条件下以低成本在经济上形成超过波长极限的抗蚀剂图案， 公开了仅有小的缺陷，以及使用该树脂组合物有效地形成微图案的方法。 用于形成微图案的树脂组合物包括含羟基的树脂，交联组分和醇溶剂，其相对于总溶剂含有醇且不超过10质量％的水。 交联组分包括在分子中具有两个或更多个丙烯酰氧基的化合物。