Process for producing L-isoleucine and ethionine by isoleucine analog
resistant strains of E. coli
    3.
    发明授权
    Process for producing L-isoleucine and ethionine by isoleucine analog resistant strains of E. coli 失效
    通过异亮氨酸类似物抗性大肠杆菌生产L-异亮氨酸和乙硫氨酸的方法

    公开(公告)号:US5362637A

    公开(公告)日:1994-11-08

    申请号:US973452

    申请日:1992-11-09

    IPC分类号: C12P13/06 C12R1/19

    摘要: Disclosed is a process for producing L-isoleucine which comprises culturing in a medium a microorganism belonging to the genus Escherichia and having resistance to an isoleucine analogue and either ethionine or argonine hydroxamate and an ability to produce L-isoleucine until L-isoleucine is accumulated in the culture, and recovering L-isoleucine therefrom.

    摘要翻译: 公开了一种生产L-异亮氨酸的方法,其包括在培养基中培养属于埃希氏杆菌属的微生物并具有对异亮氨酸类似物和乙硫氨酸或氩异羟肟酸的抗性的能力,并产生L-异亮氨酸直到L-异亮氨酸积累的能力 培养,并从中回收L-异亮氨酸。

    Process for producing aspartase and process for producing L-aspartic acid
    5.
    发明授权
    Process for producing aspartase and process for producing L-aspartic acid 失效
    生产天冬氨酸的方法和生产L-天冬氨酸的方法

    公开(公告)号:US5916782A

    公开(公告)日:1999-06-29

    申请号:US822002

    申请日:1997-03-24

    IPC分类号: C12N9/88 C12P13/20 C12P21/00

    CPC分类号: C12P13/20 C12N9/88

    摘要: Disclosed are a process for producing aspartase which comprises culturing a microorganism belonging to the genus Escherichia being capable of producing aspartase in a medium until aspartase is produced and accumulated in the culture, and recovering aspartase therefrom, wherein dissolved oxygen concentration of the medium is in the range of 0 to 1 ppm on the stage that microbial growth is middle and/or late logarithmic growth phase; and a process for producing L-aspartic acid which comprises converting fumaric acid and ammonia into L-aspartic acid in an aqueous medium in the presence of an enzyme source, wherein said enzyme source is a culture produced in accordance with said aspartase-producing process, cells isolated from the culture, or processed cells thereof.

    摘要翻译: 公开了一种生产天冬氨酸酶的方法,其包括在培养基中培养属于埃希氏杆菌属的能够产生天冬氨酸酶的微生物,直到天冬氨酸酶产生并累积在培养物中,并从其中回收天冬氨酸酶,其中培养基的溶解氧浓度在 在微生物生长是中间和/或后期对数生长期的阶段,0〜1ppm的范围; 以及L-天冬氨酸的制造方法,其特征在于,在酶源的存在下,在水性介质中将富马酸和氨转化为L-天冬氨酸,其中,所述酶源为根据所述天冬氨酰酶生产方法生产的培养物, 从培养物中分离的细胞,或其加工细胞。

    Process for producing L-amino acids by fermentation
    7.
    发明授权
    Process for producing L-amino acids by fermentation 有权
    通过发酵生产L-氨基酸的方法

    公开(公告)号:US06143552A

    公开(公告)日:2000-11-07

    申请号:US265867

    申请日:1999-03-11

    摘要: The present invention provides a process for producing an L-amino acid which comprises culturing in a nutrient medium a microorganism which is capable of producing the L-amino acid and which can not grow in a synthetic medium containing said L-amino acid as the sole nitrogen source in an amount of 5 mg/ml or below, allowing the L-amino acid to accumulate in the culture, and recovering the L-amino acid from the culture.

    摘要翻译: 本发明提供了L-氨基酸的制造方法,其包括在营养培养基中培养能够产生L-氨基酸的微生物,并且不能在含有L-氨基酸的合成培养基中生长,作为唯一的 氮源5mg / ml以下,允许L-氨基酸积累在培养物中,从培养物中回收L-氨基酸。

    PROCESS FOR PRODUCING DIPEPTIDES
    8.
    发明申请
    PROCESS FOR PRODUCING DIPEPTIDES 审中-公开
    生产皂苷的方法

    公开(公告)号:US20090197303A1

    公开(公告)日:2009-08-06

    申请号:US12097806

    申请日:2006-12-27

    CPC分类号: C12P21/02 C12N9/93

    摘要: The present invention provides: a protein having dipeptide-synthesizing activity; DNA encoding the protein; a recombinant DNA comprising the DNA; a transformant transformed with the recombinant DNA; a process for producing the protein having dipeptide-synthesizing activity using the transformant or the like; a process for producing a dipeptide using the protein having dipeptide-synthesizing activity; and a process for producing a dipeptide using, as an enzyme source, a culture of a transformant or a microorganism which produces the protein having dipeptide-synthesizing activity or the like.

    摘要翻译: 本发明提供:具有二肽合成活性的蛋白质; 编码蛋白质的DNA; 包含DNA的重组DNA; 用重组DNA转化的转化体; 使用转化体等制备具有二肽合成活性的蛋白质的方法; 使用具有二肽合成活性的蛋白质生产二肽的方法; 使用产生具有二肽合成活性的蛋白质的转化体或微生物的培养物作为酶源来生产二肽的方法。

    Process for Producing Dipeptides
    9.
    发明申请
    Process for Producing Dipeptides 审中-公开
    生产二肽的方法

    公开(公告)号:US20070218525A1

    公开(公告)日:2007-09-20

    申请号:US11547491

    申请日:2005-03-04

    IPC分类号: C12P1/04

    CPC分类号: C07K5/06 C12N9/93 C12P21/02

    摘要: The present invention provides a process for producing a dipeptide other than D-alanyl-D-alanine and D-alanyl-D-serine using, as an enzyme source, a culture of a microorganism having the ability to produce a protein having D-alanine-D-alanine ligase activity or a treated matter of the culture, and a process for producing a dipeptide comprising D-amino acid using, as enzyme sources, a culture of a microorganism having the ability to produce the D-amino acid or a treated matter of the culture and a culture of a microorganism having the ability to produce a protein having D-alanine-D-alanine ligase activity or a treated matter of the culture.

    摘要翻译: 本发明提供了使用D-丙氨酸-D-丙氨酸和D-丙氨酰-D-丝氨酸以外的二肽的制造方法,其使用具有产生具有D-丙氨酸的蛋白质的能力的微生物的培养物作为酶源 D-丙氨酸连接酶活性或培养物的处理物质,以及使用具有生产D-氨基酸能力的微生物的培养物或经处理的D-氨基酸的生产二氨基酸的方法,所述二肽包含D-氨基酸,作为酶源, 培养物质和具有产生具有D-丙氨酸-D-丙氨酸连接酶活性的蛋白质的能力的微生物的培养物或培养物的处理物质。