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公开(公告)号：US08088838B2
公开(公告)日：2012-01-03
申请号：US12393192
申请日：2009-02-26
申请人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee , Ching-Ting Tsao
发明人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee , Ching-Ting Tsao
CPC分类号： A61K6/0067 , A61K6/0091 , A61K6/0038 , C08L75/04 , A61K6/083
摘要： The present invention discloses a cone material in endodontic treatment. The cone material comprises a thermoplastic polyurethane and a filler. The thermoplastic polyurethane is formed by a. isophorone diisocyanate (IPDI) or hexamethylene diisocyanate (HDI), b. poly(butyleneadipate) glycol (PBA) and c. chain extender, wherein the molar ratio of PBA and the diisocyanate is equal to or more than 0.8. By changing the molar composition of the components such as polyol and diisocyanate, physical and chemical property of the disclosed cone material in endodontic treatment can be adjusted.
摘要翻译： 本发明公开了牙髓治疗中的锥形材料。 锥形材料包括热塑性聚氨酯和填料。 热塑性聚氨酯由a形成。 异佛尔酮二异氰酸酯（IPDI）或六亚甲基二异氰酸酯（HDI），b。 聚（己二酸丁二醇酯）二醇（PBA）和c。 扩链剂，其中PBA和二异氰酸酯的摩尔比等于或大于0.8。 通过改变多元醇和二异氰酸酯等组分的摩尔组成，可以调节根管治疗中公开的锥体材料的物理和化学性质。
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公开(公告)号：US20080319103A1
公开(公告)日：2008-12-25
申请号：US11765575
申请日：2007-06-20
申请人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
发明人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
IPC分类号： A61K6/09
CPC分类号： A61K6/0032 , C08L75/04
摘要： The present invention discloses a Polyurethane (PU) composite material comprising a thermoplastic polyurethane and a filler. The thermoplastic polyurethane comprises a linear polyurethane main-chain, and the polyurethane main-chain comprises a soft segment and a hard segment. The hard segment of the polyurethane main-chain is formed by a diisocyanate and a chain extender, and the soft segment of the polyurethane main-chain is formed by a polyol. The present invention also teaches the application of the disclosed thermoplastic polyurethane composite material in dental root canal material.
摘要翻译： 本发明公开了一种包含热塑性聚氨酯和填料的聚氨酯（PU）复合材料。 热塑性聚氨酯包括线性聚氨酯主链，聚氨酯主链包括软链段和硬链段。 聚氨酯主链的硬链段由二异氰酸酯和扩链剂形成，聚氨酯主链的软链段由多元醇形成。 本发明还教导了所公开的热塑性聚氨酯复合材料在牙根管材料中的应用。
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公开(公告)号：US07977406B2
公开(公告)日：2011-07-12
申请号：US12339384
申请日：2008-12-19
申请人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
发明人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
CPC分类号： A61K6/0038 , C08L75/16
摘要： The present invention discloses an endodontic sealer which comprises a urethane-monoacrylate oligomer, a diluting monomer, at least one photo-initiator, at least one thermal-initiator, and a filler, wherein the urethane-monoacrylate oligomer is obtained by firstly reacting the acrylate with the diisocyanate to form an intermediate with only one isocyanate group, and then reacting the intermediate with the polyol to form the desired urethane-monoacrylate oligomer.
摘要翻译： 本发明公开了一种牙髓质封口剂，其包含氨基甲酸酯 - 单丙烯酸酯低聚物，稀释单体，至少一种光引发剂，至少一种热引发剂和填料，其中所述氨基甲酸酯 - 单丙烯酸酯低聚物是通过首先使丙烯酸酯 与二异氰酸酯形成仅具有一个异氰酸酯基团的中间体，然后使中间体与多元醇反应形成所需的氨基甲酸酯 - 单丙烯酸酯低聚物。
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公开(公告)号：US20090156710A1
公开(公告)日：2009-06-18
申请号：US12393192
申请日：2009-02-26
申请人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee , Ching-Ting Tsao
发明人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee , Ching-Ting Tsao
IPC分类号： A61K6/09
CPC分类号： A61K6/0067 , A61K6/0091 , A61K6/0038 , C08L75/04 , A61K6/083
摘要： The present invention discloses a cone material in endodontic treatment. The cone material comprises a thermoplastic polyurethane and a filler. The thermoplastic polyurethane is formed by a. isophorone diisocyanate (IPDI) or hexamethylene diisocyanate (HDI), b. poly(butyleneadipate) glycol (PBA) and c. chain extender, wherein the molar ratio of PBA and the diisocyanate is equal to or more than 0.8. By changing the molar composition of the components such as polyol and diisocyanate, physical and chemical property of the disclosed cone material in endodontic treatment can be adjusted.
摘要翻译： 本发明公开了牙髓治疗中的锥形材料。 锥形材料包括热塑性聚氨酯和填料。 热塑性聚氨酯由a形成。 异佛尔酮二异氰酸酯（IPDI）或六亚甲基二异氰酸酯（HDI），b。 聚（己二酸丁二醇酯）二醇（PBA）和c。 扩链剂，其中PBA和二异氰酸酯的摩尔比等于或大于0.8。 通过改变多元醇和二异氰酸酯等组分的摩尔组成，可以调节根管治疗中公开的锥体材料的物理和化学性质。
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公开(公告)号：US20090131552A1
公开(公告)日：2009-05-21
申请号：US12339384
申请日：2008-12-19
申请人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
发明人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
IPC分类号： A61K6/09
CPC分类号： A61K6/0038 , C08L75/16
摘要： The present invention discloses an endodontic sealer which comprises a urethane-monoacrylate oligomer, a diluting monomer, at least one photo-initiator, at least one thermal-initiator, and a filler, wherein the urethane-monoacrylate oligomer is obtained by firstly reacting the acrylate with the diisocyanate to form an intermediate with only one isocyanate group, and then reacting the intermediate with the polyol to form the desired urethane-monoacrylate oligomer.
摘要翻译： 本发明公开了一种牙髓质封口剂，其包含氨基甲酸酯 - 单丙烯酸酯低聚物，稀释单体，至少一种光引发剂，至少一种热引发剂和填料，其中所述氨基甲酸酯 - 单丙烯酸酯低聚物是通过首先使丙烯酸酯 与二异氰酸酯形成仅具有一个异氰酸酯基团的中间体，然后使中间体与多元醇反应形成所需的氨基甲酸酯 - 单丙烯酸酯低聚物。
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公开(公告)号：US20080319098A1
公开(公告)日：2008-12-25
申请号：US11765591
申请日：2007-06-20
申请人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
发明人： Kuo-Huang Hsieh , Chun-Pin Lin , Ken-Hsuan Liao , Chung-Yi Lee
CPC分类号： A61K6/0038 , C08L75/16
摘要： The present invention discloses an endodontic sealer which comprises a urethane-acrylate oligomer, a diluting monomer, at least one photo-initiator, at least one thermal-initiator, and a filler, wherein the urethane-acrylate oligomer is obtained by firstly reacting the acrylate with the diisocyanate to form an intermediate with only one isocyanate group, and then reacting the intermediate with the polyol to form the desired urethane-acrylate oligomer.
摘要翻译： 本发明公开了一种牙髓质封口剂，其包含氨基甲酸酯 - 丙烯酸酯低聚物，稀释单体，至少一种光引发剂，至少一种热引发剂和填料，其中所述氨基甲酸酯 - 丙烯酸酯低聚物是通过首先使丙烯酸酯 与二异氰酸酯形成仅具有一个异氰酸酯基的中间体，然后使中间体与多元醇反应形成所需的氨基甲酸酯 - 丙烯酸酯低聚物。
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公开(公告)号：US20060149392A1
公开(公告)日：2006-07-06
申请号：US11295303
申请日：2005-12-06
申请人： Kuo-Huang Hsieh , Ken-Yu Chang , Chun-Pin Lin , Liou Horng , Yung-Hsin Lin
发明人： Kuo-Huang Hsieh , Ken-Yu Chang , Chun-Pin Lin , Liou Horng , Yung-Hsin Lin
CPC分类号： A61L31/148 , A61F2/30756 , A61F2002/2817 , A61F2002/30062 , A61F2002/30677 , A61F2002/30678 , A61F2210/0004 , A61F2310/00293 , A61F2310/00365 , A61F2310/00383 , A61F2310/00796 , A61L27/20 , A61L27/46 , A61L27/58 , A61L31/042 , A61L31/127 , C08L5/08
摘要： The present invention is directed to compositions and methods of using compositions comprising a scaffold with growth factors chemically immobilized thereto for inducing chondrogenesis and/or osteogenesis when implanted in vivo or osteogenesis or chondrogenesis in cultures in vitro. The compositions and methods enhance bone and cartilage growth. Also described are compositions and methods for targeted drug delivery.
摘要翻译： 本发明涉及组合物和方法，所述组合物包含具有化学固定于其上的生长因子的支架的组合物，用于在体内植入体内或在体外培养中的成骨或软骨形成时诱导软骨形成和/或成骨。 组合物和方法增强骨和软骨生长。 还描述了用于靶向药物递送的组合物和方法。
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8.发明授权公开(公告)号：US08889106B2
公开(公告)日：2014-11-18
申请号：US13931153
申请日：2013-06-28
申请人： Feng-Huei Lin , Chun-Pin Lin , Hsuan-Yu Chen , Tzu-Piao Tang , Hsu-Wei Fang , Chung-King Hsu , Chia-Ming Chang
发明人： Feng-Huei Lin , Chun-Pin Lin , Hsuan-Yu Chen , Tzu-Piao Tang , Hsu-Wei Fang , Chung-King Hsu , Chia-Ming Chang
摘要： A non-alcohol mouthwash composition without chemical antibacterial medicament is disclosed. The non-alcohol mouthwash composition includes from 0.03% to 1.5% of γ-polyglutamic acid (γ-PGA) and from 0.5% to 4% of surfactant, all percentages based on the total weight of the mouthwash composition. The non-alcohol mouthwash composition preferably includes from 0.4% to 1.5% by weight, or more preferably from 0.8% to 1.3% by weight, of γ-PGA. Containing no chemical antibacterial medicament, the non-alcohol mouthwash composition can effectively inhibit bacterial growth in the oral cavity without irritating the oral mucosa.
摘要翻译： 公开了一种不含化学抗菌药物的非酒精漱口剂组合物。 非酒精漱口剂组合物含有0.03％〜1.5％的γ-聚谷氨酸（γ-PGA）和0.5％〜4％的表面活性剂，所有百分比均基于漱口水组合物的总重量。 非醇漱口剂组合物优选含有0.4〜1.5重量％，更优选0.8〜1.3重量％的γ-PGA。 不含任何化学抗菌药物，非酒精漱口水组合物可有效抑制口腔细菌生长而不刺激口腔黏膜。
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公开(公告)号：US20090257964A1
公开(公告)日：2009-10-15
申请号：US12487896
申请日：2009-06-19
申请人： Bor-Shiunn Lee , Da-Ming Wang , Juin-Yih Lai , Chun-Pin Lin , Chun-Yu Chen , Fang-Yu Liu , Hao-Ting Wang
发明人： Bor-Shiunn Lee , Da-Ming Wang , Juin-Yih Lai , Chun-Pin Lin , Chun-Yu Chen , Fang-Yu Liu , Hao-Ting Wang
摘要： The present invention discloses fluoride-releasing strips for caries prevention, wherein the fluoride-releasing strips comprises a colloidal fluoride-containing solution for releasing fluorine ion and a support substrate. A colloidal fluoride-containing solution comprises a fluoride solution, at least one buffer, at least one moisturizer and a carboxymethyl cellulose (CMC). The concentration of fluoride ions in said colloidal fluoride-containing solution ranges from 2500 ppm to ppm. The support substrate is waterproof material and the colloidal fluoride-containing solution is applied on the support substrate.
摘要翻译： 本发明公开了一种用于防止龋齿的氟化物释放条，其中氟化物释放条包括用于释放氟离子的胶态含氟化物溶液和支撑基底。 含胶态氟化物的溶液包含氟化物溶液，至少一种缓冲剂，至少一种保湿剂和羧甲基纤维素（CMC）。 所述胶体状含氟化物溶液中的氟离子的浓度为2500ppm〜ppm。 支撑基板是防水材料，并且将含胶体的氟化物溶液施加在支撑基板上。
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10.发明申请Dynamic time sequence control device and its method for word matching circuit 审中-公开动态时序控制装置及其字符匹配电路方法公开(公告)号：US20070109829A1
公开(公告)日：2007-05-17
申请号：US11272690
申请日：2005-11-15
申请人： Chi-Sheng Lin , Chun-Ming Huang , Lan-Da Van , Nien-Hsiang Chang , Chun-Pin Lin , Chih-Hsien Hsu , Chau-Chin Wang
发明人： Chi-Sheng Lin , Chun-Ming Huang , Lan-Da Van , Nien-Hsiang Chang , Chun-Pin Lin , Chih-Hsien Hsu , Chau-Chin Wang
IPC分类号： G11C15/00
CPC分类号： G11C15/04
摘要： A dynamic time sequence control device and its method for a word matching circuit. The word matching circuit includes a first switch connected between an input voltage and a node to respond to a control signal generated by a pre-charging circuit so that within a pre-charging phase period a current is generated to flow through a capacitor to generate a charging voltage. The node is connected to multiple data memories and matching circuits so that the matching result can be outputted through the node. The dynamic time sequence control device includes a second switch connected between the first switch and the node. A third switch is connected between the data memory and matching circuit and a self time sequence controller has a threshold value to respond to the control signal and to conduct the second switch and turn off the third switch during the pre-charging phase period, meanwhile, it turns off the second switch and conducts the third switch when the charging voltage is detected to be larger than threshold value. The self time sequence controller detects the output voltage of the node and outputs the data matching result during a value-acquisition phase period.
摘要翻译： 一种动态时序控制装置及其字符匹配电路的方法。 字匹配电路包括连接在输入电压和节点之间的第一开关，以响应由预充电电路产生的控制信号，使得在预充电阶段期间内产生电流以流过电容器以产生 充电电压。 节点连接到多个数据存储器和匹配电路，以便可以通过节点输出匹配结果。 动态时序控制装置包括连接在第一开关和节点之间的第二开关。 第三开关连接在数据存储器和匹配电路之间，自适应时序控制器具有阈值以响应控制信号并导通第二开关并在预充电阶段期间关闭第三开关， 当检测到充电电压大于阈值时，它关闭第二开关并导通第三开关。 自适应时序控制器检测节点的输出电压，并在数据采集阶段期间输出数据匹配结果。
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