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    Method of packaging and sterilizing disposable articles for surgical operations and such a package
    3.
    发明申请
    Method of packaging and sterilizing disposable articles for surgical operations and such a package 审中-公开
    用于外科手术的一次性物品的包装和消毒方法以及这种包装

    公开(公告)号：US20060231443A1

    公开(公告)日：2006-10-19

    申请号：US10543400

    申请日：2004-02-13

    申请人： Peter Jonasson ,  Simon Smith ,  Jean-Michel Van Der Hofstadt ,  Phil Cooper

    发明人： Peter Jonasson ,  Simon Smith ,  Jean-Michel Van Der Hofstadt ,  Phil Cooper

    IPC分类号： A61B19/02 ,  B65B55/02 ,  A61L2/18 ,  A61L2/00 ,  B65D83/10

    CPC分类号： A61L2/206 ,  A61L2/26 ,  A61L2202/182 ,  A61L2202/24 ,  B65B11/58 ,  B65B55/04

    摘要： A method of packaging and sterilizing disposable articles for surgical operations, in which several surgical articles are packed in a first package that is packed in a transport package and thereafter transported to a plant for sterilizing with the aid of ethylene oxide, whereafter the first package is sterilized in this plant. A second package containing sterile packaged surgical articles of a type, that can not sustain sterilizing, or for other reasons should not be sterilized with ethylene oxide, is brought together with the first package before this package is packed into the transport package and before this package is transported to the sterilizing plant, the second package being impermeable to ethylene oxide. A transport package used in the method and a package for sterile packaged articles, which can not sustain sterilizing or should not be sterilized with ethylene oxide is also disclosed.

    摘要翻译： 一种用于外科手术的一次性物品的包装和消毒方法，其中将几个外科用品包装在包装在运输包装中的第一包装中，然后运送到植物中借助于环氧乙烷进行灭菌，之后第一包装 在该植物中灭菌。 第二个包装类型的无菌包装的外科用品，不能维持消毒，或由于其他原因，不应与环氧乙烷一起消毒，在将该包装装入运输包装之前并在该包装之前与第一包装物一并包装 被运送到灭菌装置，第二包装对环氧乙烷是不可渗透的。 还公开了用于该方法的运输包装和用于无菌包装制品的包装，其不能维持灭菌或不应用环氧乙烷灭菌。

    Powder inhaler
    4.
    发明申请
    Powder inhaler 有权
    粉末吸入器

    公开(公告)号：US20050183723A1

    公开(公告)日：2005-08-25

    申请号：US11045631

    申请日：2005-01-28

    申请人： John Pinon ,  Sameer Shirgaonkar ,  Christopher Smith ,  Simon Burge ,  Max Middleton ,  David Ahern ,  Matthew Sarkar ,  Ben Arlett ,  Emma Lye ,  Simon Smith

    发明人： John Pinon ,  Sameer Shirgaonkar ,  Christopher Smith ,  Simon Burge ,  Max Middleton ,  David Ahern ,  Matthew Sarkar ,  Ben Arlett ,  Emma Lye ,  Simon Smith

    IPC分类号： A61M15/00 ,  G06M1/04 ,  G06M1/24 ,  B05D7/14 ,  A61M16/00

    CPC分类号： A61M15/0065 ,  A61M15/0026 ,  A61M15/0075 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2206/16 ,  G06M1/04 ,  G06M1/045 ,  G06M1/248

    摘要： A powder inhaler includes a container for storing powdered medicament. A metering member has a dosing recess and is moveable between a filling position in which the dosing recess is in alignment with an opening of the container, and an inhalation position in which it is in alignment with an inhalation channel. A mouthpiece is in communication with the inhalation channel for enabling inhalation of the dose of powdered medicament when in the inhalation position. A protective member provided between the metering member and the inhalation channel is moveable between a closed position in which the protective member covers the dosing recess, thereby preventing powdered medicament contained in the dosing recess from entering the inhalation channel, and an open position in which the protective member does not cover the dosing recess, thereby exposing the dosing recess to the inhalation channel for enabling inhalation of the dose of the powdered medicament.

    摘要翻译： 粉末吸入器包括用于储存粉末状药物的容器。 计量构件具有计量凹槽，并且可以在填充位置之间移动，其中计量凹槽与容器的开口对准，以及吸入位置，其中吸入位置与吸入通道对齐。 吸嘴与吸入通道连通，用于在吸入位置时能够吸入剂量的粉末状药物。 设置在计量构件和吸入通道之间的保护构件可在闭合位置之间移动，在关闭位置中保护构件覆盖定量凹槽，从而防止包含在计量凹槽中的粉末药物进入吸入通道，并且打开位置 保护构件不覆盖定量凹槽，从而将计量凹槽暴露于吸入通道，以便吸入剂量的粉末状药物。

    NASAL DELIVERY DEVICES
    5.
    发明申请
    NASAL DELIVERY DEVICES 审中-公开
    NASAL交付设备

    公开(公告)号：US20160051778A1

    公开(公告)日：2016-02-25

    申请号：US14674103

    申请日：2015-03-31

    申请人： Per Gisle Djupesland ,  Colin David Sheldrake ,  Simon Smith ,  Rachel Striebig ,  Andy Pidgeon ,  Tom St. Quintin

    发明人： Per Gisle Djupesland ,  Colin David Sheldrake ,  Simon Smith ,  Rachel Striebig ,  Andy Pidgeon ,  Tom St. Quintin

    IPC分类号： A61M15/08 ,  A61M15/00

    摘要： A nasal delivery device for and method of delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a body assembly including a mouthpiece unit which includes a mouthpiece through which the subject in use exhales, and a substance-supply unit which is fluidly connected to the mouthpiece unit and actuatable to provide particulate substance for delivery to the nasal airway of the subject; wherein the body assembly is configured to receive a replaceable nosepiece unit which includes a nosepiece and contains a container containing particulate substance.

    摘要翻译： 一种用于将颗粒物质递送到受试者的鼻气道的鼻输送装置和方法，所述输送装置包括：主体组件，其包括接口单元，所述接口单元包括用于使用呼气的受试者的吸口，以及物质供应单元， 流体地连接到接口单元并且可致动以提供用于输送到对象的鼻气道的颗粒物质; 其特征在于，所述主体组件构造成容纳包括喷嘴的可替换的喷嘴单元，并且容纳含有颗粒物质的容器。

    Asynchronous clock domain crossing jitter randomiser
    6.
    发明授权
    Asynchronous clock domain crossing jitter randomiser 失效
    异步时钟域交叉抖动随机化

    公开(公告)号：US07640151B2

    公开(公告)日：2009-12-29

    申请号：US10812103

    申请日：2004-03-30

    申请人： Simon Smith ,  Geoff Barrett ,  Martin Vickers

    发明人： Simon Smith ,  Geoff Barrett ,  Martin Vickers

    IPC分类号： G06F17/50

    CPC分类号： G06F17/5022

    摘要： A method and system for simulation of an electronic circuit is provided, the circuit being represented by a network of a plurality of logic elements, the circuit comprising first and second asynchronous clock domains, whereby jitter elements are additionally inserted at predetermined portions of circuit boundaries between the first and second clock domains, the jitter elements being represented as logic elements, the values of which are randomly set.

    摘要翻译： 提供了一种用于模拟电子电路的方法和系统，该电路由多个逻辑元件的网络表示，该电路包括第一和第二异步时钟域，由此将抖动元件另外插入在电路边界的预定部分 第一和第二时钟域，抖动元件被表示为逻辑元件，其值是随机设置的。

    INFERENCING USER INTEREST
    7.
    发明申请
    INFERENCING USER INTEREST 审中-公开
    感染用户兴趣

    公开(公告)号：US20090083211A1

    公开(公告)日：2009-03-26

    申请号：US12130983

    申请日：2008-05-30

    申请人： Alok Sinha ,  Delane Hewett ,  Simon Smith

    发明人： Alok Sinha ,  Delane Hewett ,  Simon Smith

    IPC分类号： G06N5/04 ,  G06F7/06 ,  G06F17/30

    CPC分类号： G06F16/288 ,  G06F16/951

    摘要： Methods and systems for providing a virtual network of real-world entities are provided. In various embodiments, the methods and systems receive a database identifying real-world entities wherein the database can include relationships between entities and attributes. Some attributes can be associated with strengths. Upon receiving a search query from a user, the methods and systems can dynamically match entities based on the received query and the strengths to provide a response to the received search query.

    摘要翻译： 提供了用于提供真实世界实体虚拟网络的方法和系统。 在各种实施例中，方法和系统接收识别真实世界实体的数据库，其中数据库可以包括实体和属性之间的关系。 一些属性可以与优势相关联。 一旦从用户接收到搜索查询，方法和系统可以基于接收到的查询和强度来动态地匹配实体以向接收的搜索查询提供响应。

    Methods for Assessing the Predisposition or Susceptibility to COPD
    10.
    发明申请
    Methods for Assessing the Predisposition or Susceptibility to COPD 审中-公开
    评估COPD倾向或易感性的方法

    公开(公告)号：US20090149428A1

    公开(公告)日：2009-06-11

    申请号：US11719607

    申请日：2005-11-16

    申请人： Simon Smith

    发明人： Simon Smith

    IPC分类号： A61K31/522 ,  C12Q1/68 ,  A61K31/197 ,  A61P11/00 ,  A61K31/56 ,  C07H21/00

    CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158

    摘要： This invention relates to novel associations between polymorphisms in the genes encoding the human Epithelial Na+ Channel (ENaC) and COPD. More particularly, the invention relates to a method for assessing the predisposition and/or susceptibility of an individual to COPD, which method comprises detecting the presence of a polymorphism in one or more human ENaC-encoding genes, in particular position 3870 of SEQ ID:1 encoding SCNN1B or position 10544 of SEQ ID NO: 2 encoding SCNN1G. The invention also relates to a method of treating a human identified as having a polymorphism in one or more human ENaC-encoding genes with a drug capable of treating COPD.

    摘要翻译： 本发明涉及编码人上皮Na +通道（ENaC）和COPD的基因的多态性之间的新的关联。 更具体地，本发明涉及用于评估个体对COPD的易感性和/或易感性的方法，该方法包括检测在一个或多个人ENaC编码基因，特别是SEQ ID NO：383的位置3870中多态性的存在。 1编码SCNN1B或编码SCNN1G的SEQ ID NO：2的位置10544。 本发明还涉及一种用能够治疗COPD的药物治疗被鉴定为在一种或多种人类ENaC编码基因中具有多态性的人的方法。