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1.发明授权公开(公告)号：US06667803B1
公开(公告)日：2003-12-23
申请号：US09584990
申请日：2000-06-01
IPC分类号： G01J342
CPC分类号： G01N21/3151 , A61B5/0059 , A61B2560/0223 , A61B2560/0233 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0232 , G01J3/0291 , G01J3/28 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/3563 , G02B6/3825 , G02B6/3885 , G02B6/4249 , G02B6/4298
摘要： A spectrophotometric instrument including light signal sources, a detector, a processor/controller, a probe and a calibration device. The light signal sources include a source of measurement light signals having measurement light wavelengths and a source of a calibration light signal at a calibration detection wavelength which is different than the measurement light wavelengths. The probe has one or more send fibers coupled to the measurement and calibration light signal sources for transmitting the measurement light signals and the calibration light signal into tissue, and one or more receive fibers for receiving light including the measurement light signals and the calibration light signal. The calibration device is adapted to receive the probe and has an optical filter for transmitting the measurement light signals but not the calibration light signal. The detector is coupled to the receive fibers to generate electrical signals representative of the light received at the receive fibers. The processor/controller is coupled to the detector and initiates a calibration procedure when the calibration light signal is not detected.
摘要翻译： 包括光信号源，检测器，处理器/控制器，探针和校准装置的分光光度仪器。 光信号源包括具有测量光波长的测量光信号源和与测量光波长不同的校准检测波长的校准光信号源。 探头具有耦合到测量和校准光信号源的一个或多个发送光纤，用于将测量光信号和校准光信号传输到组织中，以及一个或多个接收光纤，用于接收包括测量光信号和校准光信号的光 。 校准装置适于接收探头并且具有用于传送测量光信号而不是校准光信号的滤光器。 检测器耦合到接收光纤以产生代表在接收光纤处接收的光的电信号。 当未检测到校准光信号时，处理器/控制器耦合到检测器并启动校准程序。
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2.发明授权Signal acquisition and processing system for reduced output signal drift in a spectrophotometric instrument 失效信号采集和处理系统，用于降低分光光度仪器中的输出信号漂移公开(公告)号：US06377840B1
公开(公告)日：2002-04-23
申请号：US09585089
申请日：2000-06-01
IPC分类号： A61B505
CPC分类号： A61B5/1495 , A61B5/0059 , A61B5/14552 , A61B5/6833 , A61B2560/0223 , A61B2560/0233 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0232 , G01J3/0291 , G01J3/28 , G01J3/42 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/31 , G01N21/3151 , G01N21/359 , G02B6/2808 , G02B6/3817 , G02B6/3825 , G02B6/3878 , G02B6/3885 , G02B6/3895 , G02B6/4249 , G02B6/4298
摘要： A spectrophotometric instrument including a source of measurement light signals having measurement light wavelengths, and a probe having a tissue-engaging surface, a plurality of send fibers coupled to the measurement light signal source for transmitting the measurement light signals to the tissue-engaging surface, and a plurality of receive fibers for receiving light including the measurement light signals after the measurement light has been transmitted through the tissue. The instrument also has reference signal optics coupled to the measurement light signal between the measurement light signal source and the tissue-engaging surface for transmitting a reference light signal portion of the measurement light signal, a detector for generating electrical signals representative of the measurement light signals and the reference light signals, optical paths for coupling the measurement light signal from the receive fibers and the reference light signal portion from the reference signal optics to the detector, and an optical path control for selectively allowing either the measurement light signal portion or the reference light signal portion to the detector. The optical path control enables the detector to output a reference light sample value when the reference light signal portion is coupled to the detector, and to output a measurement light sample value when the measurement light signal portion is coupled to the detector.
摘要翻译： 一种分光光度仪器，包括具有测量光波长的测量光信号源和具有组织接合表面的探针，耦合到测量光信号源的多个发送光纤，用于将测量光信号传输到组织接合表面， 以及多个接收光纤，用于在测量光已经透射通过组织之后接收包括测量光信号的光。 仪器还具有耦合到测量光信号源和组织接合表面之间的测量光信号的参考信号光学，用于传输测量光信号的参考光信号部分，用于产生表示测量光信号的电信号的检测器 和参考光信号，用于将来自接收光纤的测量光信号和参考光信号部分从参考信号光学器件耦合到检测器的光路，以及光路控制器，用于选择性地允许测量光信号部分或参考 光信号部分到检测器。 当参考光信号部分耦合到检测器时，光路控制使得检测器能够输出参考光采样值，并且当测量光信号部分耦合到检测器时，输出测量光采样值。
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3.发明授权公开(公告)号：US06481899B1
公开(公告)日：2002-11-19
申请号：US09585487
申请日：2000-06-01
IPC分类号： G02B636
CPC分类号： G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0232 , G01J3/0291 , G01N21/274 , G01N21/3151 , G01N21/3563 , G02B6/3825 , G02B6/3878 , G02B6/3885 , G02B6/4249 , G02B6/4298
摘要： An optical connector latch to optically couple at least one optical fiber ferrule on an interface housing with an optics receptacle mount on an instrument and a method of using the same. The optical connector latch comprises one or more shell pegs adapted to advance the interface housing into engagement with the optics receptacle mount. One or more ferrule pins are adapted to extend through latch holes in the interface housing and latch holes in the optics receptacle mount to engage with the optical fiber ferrule. A drive mechanism is provided to drive the shell pegs and the ferrule pins toward the optics receptacle mount.
摘要翻译： 一种光学连接器闩锁，用于将接口壳体上的至少一个光纤套圈光学耦合到仪器上的光学器件插座安装件及其使用方法。 光学连接器闩锁包括一个或多个壳钉，其适于将接口壳体推进与光学插座安装座接合。 一个或多个套圈销适于延伸通过接口壳体中的闩锁孔和光学插座安装件中的闩锁孔，以与光纤套圈啮合。 提供驱动机构以将壳钉和套圈销朝向光学插座安装座驱动。
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公开(公告)号：US06839583B1
公开(公告)日：2005-01-04
申请号：US09584862
申请日：2000-06-01
申请人： Mark S. Lewandowski , Dean E. Myers , Joseph P. Ortner , Kenneth R. Quast , Diane L. Rupp , Mark A. Schmidt
发明人： Mark S. Lewandowski , Dean E. Myers , Joseph P. Ortner , Kenneth R. Quast , Diane L. Rupp , Mark A. Schmidt
IPC分类号： A61B5/00 , G01J3/02 , G01J3/28 , G01J3/42 , G01N21/25 , G01N21/27 , G01N21/31 , G01N21/35 , G02B6/28 , G02B6/38 , G02B6/42
CPC分类号： A61B5/6833 , A61B5/0059 , A61B5/14552 , A61B2560/0223 , A61B2560/0233 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0232 , G01J3/0291 , G01J3/28 , G01J3/42 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/3151 , G02B6/2808 , G02B6/3825 , G02B6/3885 , G02B6/4249 , G02B6/4298
摘要： A disposable tip adapted for use in connection with an optical probe of an instrument. The tip includes a one-piece molded elastomeric base member having a boot and an opaque tissue-engaging surface. The boot releasably mates with and provides an interference/friction fit to the probe. The tissue-engaging surface surrounds and extends from the boot. A window in the base member extends into the boot to transmit light between the probe and tissue. A layer of optically transparent material covers the window on the tissue-engaging surface. Adhesive on the tissue-engaging surface of the base member releasably secures the probe to the tissue being analyzed.
摘要翻译： 适用于与仪器的光学探针结合使用的一次性尖端。 尖端包括具有靴子和不透明的组织接合表面的单件模制的弹性体底座构件。 靴子与探头可释放地配合并提供干涉/摩擦配合。 组织接合表面围绕并从靴子延伸。 基部构件中的窗口延伸到靴子中，以在探针和组织之间透射光。 一层光学透明的材料覆盖组织接合表面上的窗口。 基底构件的组织接合表面上的粘合剂将探针可释放地固定在被分析的组织上。
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公开(公告)号：US06892006B2
公开(公告)日：2005-05-10
申请号：US10288184
申请日：2002-11-05
CPC分类号： G01J3/02 , A61B5/14552 , A61B2562/146 , G01J3/0218 , G01J3/10 , G02B6/2808 , G02B6/3845 , G02B6/3873 , G02B6/3885
摘要： An optical structure for combining light from a plurality of individual optical fibers into a single optical transmission device. The structure can be incorporated into the optical probe of a spectrophotometric instrument and includes a plurality of optical send fibers having input and output ends and an optical light mixer having input and output ends. The output ends of the send fibers are secured in optical communication with the input end of the light mixer.
摘要翻译： 一种用于将来自多个单独光纤的光组合成单个光传输装置的光学结构。 该结构可以结合到分光光度计的光学探针中，并且包括具有输入和输出端的多个光学发送光纤和具有输入和输出端的光学混合器。 发送光纤的输出端与光混合器的输入端光连通地固定。
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公开(公告)号：US5879294A
公开(公告)日：1999-03-09
申请号：US672625
申请日：1996-06-28
IPC分类号： G01N21/27 , A61B5/00 , A61B5/145 , A61B5/1455 , A61B5/1495 , A61B10/00 , G01J3/433 , G01N21/31
CPC分类号： G01J3/433 , A61B5/14551 , G01N21/314 , A61B2562/0242 , A61B5/14553 , A61B5/1495 , A61B5/7264
摘要： A measurement system and method for measuring a relative concentration of a first form of a chromophore having a first form and a second form. The method comprises irradiating a tissue sample with light at a plurality of wavelengths within a wavelength range within which the first and second forms of the chromophore provide an overlapping spectral response. A detector is provided that detects spectral data emitted from the tissue. Furthermore, the method comprises determining a first and a second 2d derivative spectrum value, at first and second wavelengths, respectively, within said wavelength range at which the first 2d derivative spectrum value varies with the relative concentration of the first form of the chromophore. A scaled, 2d derivative spectrum value is derived from the first and second 2d derivative spectrum values. A memory stores a correlation which provides the relative chromophore concentration as a function of the scaled, 2d derivative spectrum value. Finally, the relative concentration of the first form of the chromophore in the tissue sample is determined from the 2d derivative spectrum values and the correlation.
摘要翻译： 一种用于测量具有第一形式和第二形式的发色团的第一形式的相对浓度的测量系统和方法。 该方法包括用波长范围内的多个波长的光照射组织样本，其中发色团的第一和第二形式提供重叠的光谱响应。 提供检测器，其检测从组织发射的光谱数据。 此外，该方法包括分别在所述波长范围内的第一和第二波长处确定第一和第二2D导数光谱值，在该范围内第一2d衍生光谱值随发色团的第一形式的相对浓度而变化。 从第一和第二2D导数光谱值导出缩放的二维导数光谱值。 存储器存储提供相对发色团浓度作为缩放的二维导数谱值的函数的相关性。 最后，从2d衍生光谱值和相关性确定组织样品中发色团的第一形式的相对浓度。
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公开(公告)号：US06487343B1
公开(公告)日：2002-11-26
申请号：US09585144
申请日：2000-06-01
IPC分类号： G02B626
CPC分类号： G01J3/02 , G01J3/0218 , G01J3/0232 , G01J3/0291 , G01N21/274 , G01N21/3151 , G01N21/3563 , G02B6/2808 , G02B6/3825 , G02B6/3885 , G02B6/4249 , G02B6/4298
摘要： An optical structure for combining light from a plurality of individual optical fibers into a single optical transmission device. The structure can be incorporated into the optical probe of a spectrophotometric instrument and includes a plurality of optical send fibers having input and output ends and an optical light mixer having input and output ends. The output ends of the send fibers are secured in optical communication with the input end of the light mixer.
摘要翻译： 一种用于将来自多个单独光纤的光组合成单个光传输装置的光学结构。 该结构可以结合到分光光度计的光学探针中，并且包括具有输入和输出端的多个光学发送光纤和具有输入和输出端的光学混合器。 发送光纤的输出端与光混合器的输入端光连通地固定。
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公开(公告)号：US5593197A
公开(公告)日：1997-01-14
申请号：US403056
申请日：1995-03-13
CPC分类号： B25B7/12 , B25B27/0035 , B25B7/00 , B25B7/02
摘要： A spark plug wire puller is described which is actuated by a user squeezing a trigger biased against a handle of the tool which causes two jaw members to come together at gripping ends thereof to squeeze a wire or boot. As the user squeezes the trigger and pulls on the tool, the jaws grip the wire or boot and remove it from the spark plug. The invention is advantageous because it does not rely on a scissors action and it grips the boot in such a way so as not to damage it during the removal process.
摘要翻译： 描述了一种火花塞线拉拔器，其由用户挤压偏压在工具的把手上的触发器，该触发器使得两个钳口构件在其夹持端汇合在一起以挤压线或靴。 当用户挤压触发器并拉动工具时，钳口夹紧导线或引导并将其从火花塞中取出。 本发明是有利的，因为它不依赖于剪刀动作，并且以这样的方式抓住靴子，以便在移除过程中不会损坏靴子。
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公开(公告)号：US5857723A
公开(公告)日：1999-01-12
申请号：US847342
申请日：1997-04-23
CPC分类号： B25B7/12 , B25B27/0035 , B25B7/00 , B25B7/02
摘要： A spark plug wire puller is described which is actuated by a user squeezing a trigger biased against a handle of the tool which causes two jaw members to come together at gripping ends thereof to squeeze a wire or boot. As the user squeezes the trigger and pulls on the tool, the jaws grip the wire or boot and remove it from the spark plug. The invention is advantageous because it does not rely on a scissors action and it grips the boot in such a way so as not to damage it during the removal process.
摘要翻译： 描述了一种火花塞线拉拔器，其由用户挤压偏压在工具的把手上的触发器，该触发器使得两个钳口构件在其夹持端汇合在一起以挤压线或靴。 当用户挤压触发器并拉动工具时，钳口夹紧导线或引导并将其从火花塞中取出。 本发明是有利的，因为它不依赖于剪刀动作，并且以这样的方式抓住靴子，以便在移除过程中不会损坏靴子。
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10.发明申请VASCULAR OCCLUSION TEST APPARATUS, SYSTEMS, AND METHODS FOR ANALYZING TISSUE OXYGENATION 审中-公开用于分析组织氧化的血管闭塞测试装置，系统和方法公开(公告)号：US20120238846A1
公开(公告)日：2012-09-20
申请号：US13051140
申请日：2011-03-18
申请人： Dean E. Myers , Roger W. Schmitz , Kevin Becker
发明人： Dean E. Myers , Roger W. Schmitz , Kevin Becker
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/022
摘要： A vascular occlusion test apparatus, systems, and methods for analyzing tissue oxygen saturation levels in patients are disclosed. A system for analyzing data related to tissue oxygenation in a patient includes a blood pressure device, a tissue oxygen sensor, and a control module in communication with the blood pressure device and tissue oxygen sensor. The control module includes a processor that computes various tissue characteristics associated with tissue oxygenation, including ischemia slope and recovery slope. During a vascular occlusion test, the control module can be configured to control an inflatable cuff based on tissue oxygen measurements obtained from the tissue oxygen sensor.
摘要翻译： 公开了用于分析患者组织氧饱和度水平的血管闭塞测试装置，系统和方法。 用于分析与患者的组织氧合相关的数据的系统包括与血压装置和组织氧传感器连通的血压装置，组织氧传感器和控制模块。 控制模块包括计算与组织氧合相关的各种组织特征的处理器，包括缺血斜率和恢复斜率。 在血管闭塞测试期间，控制模块可以被配置为基于从组织氧传感器获得的组织氧测量来控制可充气袖带。
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