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    Apparatus and method for performing an anastomosis
    6.
    发明授权
    Apparatus and method for performing an anastomosis 失效
    用于进行吻合的装置和方法

    公开(公告)号：US06884251B2

    公开(公告)日：2005-04-26

    申请号：US10384250

    申请日：2003-03-06

    申请人： Paul A. Spence ,  Warren P. Williamson, IV ,  George Christakis ,  Mark Ortiz ,  Craig B. Berky ,  Douglas P. Allen ,  Matthew J. Huddleston ,  Delbert Ted Leimbach ,  Cecil R. Robinson ,  E. Dale VanHoose ,  Thomas J. Ward ,  Marty J. Warnecke

    发明人： Paul A. Spence ,  Warren P. Williamson, IV ,  George Christakis ,  Mark Ortiz ,  Craig B. Berky ,  Douglas P. Allen ,  Matthew J. Huddleston ,  Delbert Ted Leimbach ,  Cecil R. Robinson ,  E. Dale VanHoose ,  Thomas J. Ward ,  Marty J. Warnecke

    IPC分类号： A61B17/11 ,  A61B17/115 ,  A61B17/08

    CPC分类号： A61B17/11 ,  A61B17/1152 ,  A61B2017/1135 ,  A61B2017/1139

    摘要： An anastomosis is performed using a flexible mounting structure mounted on the outside of at least one vessel. Fasteners extend through the vessel and are bent towards the incision to attach the flexible mounting structure to the vessel in a manner that controls the edge of the vessel adjacent to the incision. The mounting structures are oriented on each vessel so fasteners on one mounting structure interdigitate with fasteners on the other mounting structure at the location of contact between the vessels when the two vessels are brought together. This creates two complementary sinusoidal-shaped vessel edges with peaks of one edge being accommodated in the valleys of the other edge. The peak-to-valley orientation forms a sinusoidal-shaped joint which is leak free. The fasteners are spaced so proper pressure is applied to the tissue to promote healing without leaking. Furthermore, the fasteners are sized and shaped to properly engage the tissue and bend in a desired manner. Methods and tools for carrying out the anastomosis according to the invention are also disclosed. Methods for forming the fastener and the tines having the proper characteristics are disclosed. An absorbable ring-shaped stent is also disclosed.

    摘要翻译： 使用安装在至少一个容器的外部的柔性安装结构进行吻合。 紧固件延伸穿过容器并朝向切口弯曲，以将控制与切口相邻的容器边缘的方式将柔性安装结构附接到容器。 安装结构被定向在每个容器上，因此当两个容器被接合在一起时，在一个安装结构上的紧固件与另一个安装结构上的紧固件在容器之间的接触位置处相互交错。 这产生两个互补的正弦形容器边缘，其中一个边缘的峰值被容纳在另一个边缘的谷部中。 峰 - 谷取向形成无泄漏的正弦形接头。 紧固件间隔开，以便适当的压力施加到组织以促进愈合而不泄漏。 此外，紧固件的尺寸和形状适于适当地接合组织并以期望的方式弯曲。 还公开了用于进行根据本发明的吻合的方法和工具。 公开了用于形成紧固件和具有适当特性的尖齿的方法。 还公开了可吸收的环形支架。

    Apparatus and method for performing an anastomosis
    7.
    发明授权
    Apparatus and method for performing an anastomosis 失效
    用于进行吻合的装置和方法

    公开(公告)号：US06565581B1

    公开(公告)日：2003-05-20

    申请号：US09641284

    申请日：2000-08-17

    申请人： Paul A. Spence ,  Warren P. Williamson IV ,  George Christakis ,  Mark Ortiz ,  Craig B. Berky ,  Douglas P. Allen ,  Matthew J. Huddleston ,  Delbert Ted Leimbach ,  Cecil R. Robinson ,  E. Dale VanHoose ,  Thomas J. Ward ,  Marty J. Warnecke

    发明人： Paul A. Spence ,  Warren P. Williamson IV ,  George Christakis ,  Mark Ortiz ,  Craig B. Berky ,  Douglas P. Allen ,  Matthew J. Huddleston ,  Delbert Ted Leimbach ,  Cecil R. Robinson ,  E. Dale VanHoose ,  Thomas J. Ward ,  Marty J. Warnecke

    IPC分类号： A61B1708

    CPC分类号： A61B17/11 ,  A61B17/1152 ,  A61B2017/1135 ,  A61B2017/1139

    摘要： An anastomosis is performed using a flexible mounting structure mounted on the outside of at least one vessel. Fasteners extend through the vessel and are bent towards the incision to attach the flexible mounting structure to the vessel in a manner that controls the edge of the vessel adjacent to the incision. The mounting structures are oriented on each vessel so fasteners on one mounting structure interdigitate with fasteners on the other mounting structure at the location of contact between the vessels when the two vessels are brought together. This creates two complementary sinusoidal-shaped vessel edges with peaks of one edge being accommodated in the valleys of the other edge. The peak-to-valley orientation forms a sinusoidal-shaped joint which is leak free. The fasteners are spaced so proper pressure is applied to the tissue to promote healing without leaking. Furthermore, the fasteners are sized and shaped to properly engage the tissue and bend in a desired manner. Methods and tools for carrying out the anastomosis according to the invention are also disclosed. Methods for forming the fastener and the tines having the proper characteristics are disclosed. An absorbable ring-shaped stent is also disclosed.

    摘要翻译： 使用安装在至少一个容器的外侧上的柔性安装结构进行吻合。 紧固件延伸穿过容器并朝向切口弯曲，以将控制与切口相邻的容器边缘的方式将柔性安装结构附接到容器。 安装结构被定向在每个容器上，因此当两个容器被接合在一起时，在一个安装结构上的紧固件与另一个安装结构上的紧固件在容器之间的接触位置处相互交错。 这产生两个互补的正弦形容器边缘，其中一个边缘的峰值被容纳在另一个边缘的谷部中。 峰 - 谷取向形成无泄漏的正弦形接头。 紧固件间隔开，以便适当的压力施加到组织以促进愈合而不泄漏。 此外，紧固件的尺寸和形状适于适当地接合组织并以期望的方式弯曲。 还公开了用于进行根据本发明的吻合的方法和工具。 公开了用于形成紧固件和具有适当特性的尖齿的方法。 还公开了可吸收的环形支架。

    Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefore, and methods therefor
    8.
    发明授权
    Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefore, and methods therefor 有权
    因此，在处理，嵌入和切片机程序期间处理和保持组织样本的盒式和嵌入组件，因此分级装置及其方法

    公开(公告)号：US07776274B2

    公开(公告)日：2010-08-17

    申请号：US11072119

    申请日：2005-03-04

    申请人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    发明人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    IPC分类号： B01L9/00

    CPC分类号： G01N1/36 ,  B01L3/508 ,  B01L9/52 ,  B01L2300/043 ,  G01N2001/315 ,  G01N2001/366 ,  Y10T436/25

    摘要： The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.

    摘要翻译： 本公开涉及一种用于在嵌入和微型切割过程期间保持组织样本的盒，框架和模具及相关方法。 盒子可在切片机中切片，并且包括具有底壁和多个侧壁的主体。 第一侧壁和第二侧壁通常为V形以呈现与切片机叶片“V”的顶点。 盒的盖比盒的底壁更硬，以帮助定位组织样品。 盒的侧壁是穿孔的，以便显着减少必须由切片机刀片切割的盒材料的量。 在一个实施例中，为了额外地减少刀片磨损，一个侧壁上的肋相对于相对侧壁上的肋纵向偏移。 盒的上凸缘包括配置成与框架中的棘爪对准的凹陷。

    CASSETTE AND EMBEDDING ASSEMBLY FOR HANDLING AND HOLDING TISSUE SAMPLES DURING PROCESSING, EMBEDDING AND MICROTOME PROCEDURES, STAGING DEVICES THEREFOR, AND METHODS THEREFOR
    9.
    发明申请
    CASSETTE AND EMBEDDING ASSEMBLY FOR HANDLING AND HOLDING TISSUE SAMPLES DURING PROCESSING, EMBEDDING AND MICROTOME PROCEDURES, STAGING DEVICES THEREFOR, AND METHODS THEREFOR 有权
    用于处理，嵌入和微阵列程序的处理和保存组织样本的CASSETTE和嵌入式组件，其分类设备及其方法

    公开(公告)号：US20100278627A1

    公开(公告)日：2010-11-04

    申请号：US12836102

    申请日：2010-07-14

    申请人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    发明人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    IPC分类号： C12M1/00 ,  B25J1/00

    CPC分类号： G01N1/36 ,  B01L3/508 ,  B01L9/52 ,  B01L2300/043 ,  G01N2001/315 ,  G01N2001/366 ,  Y10T436/25

    摘要： The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.

    摘要翻译： 本公开涉及一种用于在嵌入和微型切割过程期间保持组织样本的盒，框架和模具及相关方法。 盒子可在切片机中切片，并且包括具有底壁和多个侧壁的主体。 第一侧壁和第二侧壁通常为V形以呈现与切片机叶片“V”的顶点。 盒的盖比盒的底壁更硬，以帮助定位组织样品。 盒的侧壁是穿孔的，以便显着减少必须由切片机刀片切割的盒材料的量。 在一个实施例中，为了额外地减少刀片磨损，一个侧壁上的肋相对于相对侧壁上的肋纵向偏移。 盒的上凸缘包括配置成与框架中的棘爪对准的凹陷。

    Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefor, and methods therefor
    10.
    发明授权
    Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefor, and methods therefor 有权
    在处理，嵌入和切片机程序期间处理和保持组织样品的盒式和嵌入组件，其分级装置及其方法

    公开(公告)号：US08609431B2

    公开(公告)日：2013-12-17

    申请号：US12836102

    申请日：2010-07-14

    申请人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    发明人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    IPC分类号： G01N1/28

    CPC分类号： G01N1/36 ,  B01L3/508 ,  B01L9/52 ,  B01L2300/043 ,  G01N2001/315 ,  G01N2001/366 ,  Y10T436/25

    摘要： The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.

    摘要翻译： 本公开涉及一种用于在嵌入和微型切割过程期间保持组织样本的盒，框架和模具及相关方法。 盒子可在切片机中切片，并且包括具有底壁和多个侧壁的主体。 第一侧壁和第二侧壁通常为V形以呈现与切片机叶片“V”的顶点。 盒的盖比盒的底壁更硬，以帮助定位组织样品。 盒的侧壁是穿孔的，以便显着减少必须由切片机刀片切割的盒材料的量。 在一个实施例中，为了额外地减少刀片磨损，一个侧壁上的肋相对于相对侧壁上的肋纵向偏移。 盒的上凸缘包括配置成与框架中的棘爪对准的凹陷。