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公开(公告)号：US08658147B2
公开(公告)日：2014-02-25
申请号：US12703286
申请日：2010-02-10
CPC分类号： A61K31/765 , A23L29/262 , A61K9/06 , A61K47/38 , A61L15/225 , A61L15/28 , A61L15/60 , C08B11/20 , C08B15/005 , C08J3/24 , C08J3/246 , C08J2301/28 , Y02E50/343 , Y02W30/47 , C08L1/26
摘要： The invention relates to a method for the preparation of a polymer hydrogel, comprising cross-linking a precursor comprising a hydrophilic polymer optionally in combination with a second hydrophilic polymer, using a polycarboxylic acid as the cross-linking agent. The invention further concerns the polymer hydrogel obtainable by the method of the invention and the use thereof in a number of different applications.
摘要翻译： 本发明涉及一种制备聚合物水凝胶的方法，其包括使用多元羧酸作为交联剂将包含亲水性聚合物的前体与第二亲水聚合物组合交联。 本发明还涉及通过本发明的方法获得的聚合物水凝胶及其在许多不同应用中的用途。
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公开(公告)号：US20100234233A1
公开(公告)日：2010-09-16
申请号：US12703286
申请日：2010-02-10
CPC分类号： A61K31/765 , A23L29/262 , A61K9/06 , A61K47/38 , A61L15/225 , A61L15/28 , A61L15/60 , C08B11/20 , C08B15/005 , C08J3/24 , C08J3/246 , C08J2301/28 , Y02E50/343 , Y02W30/47 , C08L1/26
摘要： The invention relates to a method for the preparation of a polymer hydrogel, comprising cross-linking a precursor comprising a hydrophilic polymer optionally in combination with a second hydrophilic polymer, using a polycarboxylic acid as the cross-linking agent. The invention further concerns the polymer hydrogel obtainable by the method of the invention and the use thereof in a number of different applications.
摘要翻译： 本发明涉及一种制备聚合物水凝胶的方法，其包括使用多元羧酸作为交联剂将包含亲水性聚合物的前体与第二亲水聚合物组合交联。 本发明还涉及通过本发明的方法获得的聚合物水凝胶及其在许多不同应用中的用途。
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3.发明申请Biodegradable, Super Absorbent Polymer Hydrogels and a Method For Their Preparation 审中-公开可生物降解，超吸收性聚合物水凝胶及其制备方法公开(公告)号：US20080227944A1
公开(公告)日：2008-09-18
申请号：US11722855
申请日：2005-12-28
IPC分类号： C08F251/02
CPC分类号： C08J3/246 , C08B11/20 , C08B15/00 , C08J3/075 , C08J2301/28 , C08L1/28 , C08L2666/26
摘要： The invention relates to a method for the preparation of a superabsorbent polymer hydrogel, comprising the steps of (i) crosslinking a 3% overall aqueous solution of carboxymethylcellulose sodium salt and hydroxyethylcellulose with 5% carbodiimide, in the presence of an acid catalyst; (ii) washing the gel obtained at least once by swelling in a polar organic solvent; and (iii) drying the gel by phase inversion in a non-solvent for cellulose. The invention further concerns the superabsorbent hydrogels obtainable by said method and the uses thereof.
摘要翻译： 本发明涉及一种制备超吸收聚合物水凝胶的方法，包括以下步骤：（i）在酸催化剂存在下，将3％总羧甲基纤维素钠盐和羟乙基纤维素水溶液与5％碳二亚胺交联; （ii）通过在极性有机溶剂中溶胀洗涤至少一次获得的凝胶; 和（iii）通过纤维素的非溶剂中的相转化干燥凝胶。 本发明还涉及通过所述方法获得的超吸收剂水凝胶及其用途。
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公开(公告)号：US07071327B2
公开(公告)日：2006-07-04
申请号：US10221739
申请日：2001-03-09
摘要： A superabsorbent polysaccharide can be obtained by crosslinking a polysaccharide or derivative thereof with at least 1% by weight of a flexible spacer having a chain length of at least 9 chain atoms and having terminal activated coupling groups. The flexible spacer may comprise a polyalkyleneglycol with a molecular weight from about 400 to 10,000. The coupling groups may be provided by divinyl sulphone units.
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5.发明申请METHODS AND COMPOSITIONS FOR WEIGHT MANAGEMENT AND FOR IMPROVING GLYCEMIC CONTROL 审中-公开重量管理和改进糖化控制的方法和组合公开(公告)号：US20120052151A1
公开(公告)日：2012-03-01
申请号：US13106909
申请日：2011-05-13
申请人： Alessandro Sannino , Luigi Ambrosio , Eyal S. Ron , Yishai Zohar
发明人： Alessandro Sannino , Luigi Ambrosio , Eyal S. Ron , Yishai Zohar
CPC分类号： A23L2/52 , A21D2/145 , A21D2/18 , A21D2/188 , A21D13/80 , A23G9/34 , A23L2/68 , A23L7/10 , A23L7/109 , A23L7/122 , A23L7/126 , A23L29/288 , A23L33/24 , A23L33/30 , A23V2002/00 , A61K47/38 , C08B13/00 , C08B15/005 , C08J3/075 , C08J2301/02 , C08J2301/10 , C08L1/32 , A23V2200/326 , A23V2200/32 , A23V2200/332 , A23V2200/328 , A23V2250/51082 , A23V2250/032 , A23V2200/244
摘要： The present invention provides methods, compositions and modified foods and foodstuffs useful for weight management and glycemic control.
摘要翻译： 本发明提供了可用于体重管理和血糖控制的方法，组合物和改良食品和食品。
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公开(公告)号：US10774465B2
公开(公告)日：2020-09-15
申请号：US16131186
申请日：2018-09-14
申请人： CARESILK SRLS , Alessandro Sannino
IPC分类号： D06M10/00 , D06M10/06 , A01N25/34 , A01N59/16 , D06M11/83 , D06M16/00 , C23C18/14 , D06M10/02 , D06M101/06
摘要： The invention relates to methods of depositing silver onto a substrate using a dilute silver salt solution.
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公开(公告)号：US20190218707A1
公开(公告)日：2019-07-18
申请号：US16131186
申请日：2018-09-14
摘要： The invention relates to methods of depositing silver onto a substrate using a dilute silver salt solution.
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8.发明申请METHOD FOR MANUFACTURING A DEVICE FOR REGENERATING BIOLOGICAL TISSUES, PARTICULARLY FOR REGENERATING TISSUES OF THE CENTRAL NERVOUS SYSTEM 审中-公开用于制造用于再生生物组织的装置的方法，特别用于再生中央神经系统的组织公开(公告)号：US20120214222A1
公开(公告)日：2012-08-23
申请号：US13503208
申请日：2010-10-07
申请人： Alessandro Sannino , Pietro Mortini
发明人： Alessandro Sannino , Pietro Mortini
CPC分类号： A61L27/24 , A61B17/1128 , A61B50/20 , A61B2017/00526 , A61L27/56 , A61L2430/32
摘要： A method for manufacturing a device for regenerating biological tissues, particularly for regenerating tissues of the central nervous system, and a device that can be manufactured with said method, the device comprising an outer sheath based on collagen which is substantially tubular and can be interposed between the endings of a biological tissue to be regenerated, and at least one supporting element based on collagen, which is accommodated inside the outer sheath.
摘要翻译： 一种制造用于再生生物组织的装置的方法，特别是用于再生中枢神经系统的组织的装置以及可以用所述方法制造的装置，所述装置包括基于胶原的外护套，所述外护套基本上是管状的，并且可以介于 待再生的生物组织的末端，以及容纳在外护套内的基于胶原的至少一个支撑元件。
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公开(公告)号：US20160213711A1
公开(公告)日：2016-07-28
申请号：US15008658
申请日：2016-01-28
申请人： Ilaria E. Palama , Mauro Pollini , Federica Paladini , Gianluca Accorsi , Alessandro Sannino , Giuseppe Gigli
发明人： Ilaria E. Palama , Mauro Pollini , Federica Paladini , Gianluca Accorsi , Alessandro Sannino , Giuseppe Gigli
CPC分类号： A61K33/38 , A61K9/51 , B22F1/0003 , B22F2301/255 , B22F2304/054
摘要： The present invention provides methods for inhibiting or preventing cancer cell growth using silver nanoparticles.
摘要翻译： 本发明提供了使用银纳米颗粒抑制或预防癌细胞生长的方法。
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公开(公告)号：US09353191B2
公开(公告)日：2016-05-31
申请号：US13491197
申请日：2012-06-07
CPC分类号： C08B3/12 , C08B11/08 , C08B11/12 , C08B11/20 , C08B15/005 , C08J3/075 , C08J2301/00 , C08J2301/08 , C08J2301/26 , C08J2301/28 , C08L1/08 , C08L1/284 , C08L1/286 , Y10T428/2982
摘要： The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.
摘要翻译： 本发明提供一种制备聚合物水凝胶的方法，包括以下步骤：（1）制备水溶性多糖衍生物和多元羧酸的水溶液; （2）任选地搅拌溶液，例如通过搅拌; （3）从溶液中分离多糖衍生物/多元羧酸复合物; 和（4）在至少约80℃的温度下加热多糖衍生物/多元羧酸复合物，从而使多糖与多元羧酸交联。 本发明还提供了通过本发明的方法制备的聚合物水凝胶。
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