公开(公告)号：US20190167899A1

公开(公告)日：2019-06-06

申请号：US15750791

申请日：2013-03-14

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI

IPC: A61M5/172 ,  A61M5/145 ,  A61M5/162

CPC classification number: A61M5/172 ,  A61M5/14248 ,  A61M5/14566 ,  A61M5/162 ,  A61M2005/1402 ,  A61M2005/14208 ,  A61M2005/14256 ,  A61M2005/1581 ,  A61M2005/247

Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may include a mechanical drive train. Motion of the drive train may drive priming of the device. Subsequently motion of the drive train may discharge the drug. The priming may include unsealing a drug reservoir and/or locking a door. In some embodiments, the rate of discharging may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a base that is attachable to the recipient. Optionally, motion of the drive train may be parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the motion of the drive train.

公开(公告)号：US20170080157A1

公开(公告)日：2017-03-23

申请号：US15269248

申请日：2016-09-19

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI ,  Ran HEZKIAHU

IPC: A61M5/315

CPC classification number: A61M5/31501 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/31511 ,  A61M5/31565 ,  A61M5/31583 ,  A61M2005/3143 ,  A61M2005/3151 ,  A61M2005/31518

Abstract: A method and system are disclosed for driving a plunger in a drug reservoir. In some embodiments, a variable friction element interconnects between a pushing shaft and a wall of the reservoir. For example, rotation of a driving element in a first direction relative to the pushing shaft may advance the pushing shaft in the reservoir. The friction element may have increased friction resistance to rotation of the pushing shaft in the first direction in comparison to frictional resistance to advancing the pushing shaft. For example, the increased friction may result from wedging a radial element between the pushing shaft and the wall of the reservoir.

公开(公告)号：US20150088071A1

公开(公告)日：2015-03-26

申请号：US14553399

申请日：2014-11-25

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI

IPC: A61M5/32 ,  A61M5/162

CPC classification number: A61M5/2033 ,  A61M5/142 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/1626 ,  A61M5/3204 ,  A61M5/322 ,  A61M5/3287 ,  A61M2005/14252 ,  A61M2005/1585 ,  A61M2005/206 ,  A61M2005/2073

Abstract: An apparatus (110) includes an activation mechanism (20) and a safety latch (122). The activation mechanism is operative to deploy a needle (116) to protrude out of a housing (112), the needle (116) having a longitudinal axis. The safety latch (122) is movably mounted on the housing (112) and formed with a needle opening (129) to allow the needle (116) to pass therethrough. The safety latch (122) has a first position wherein the needle (116) is aligned to pass through the needle opening (129) and a second position wherein the safety latch (122) is moved with respect to the housing (112) such that the needle (116) is blocked from movement in a direction parallel to the longitudinal axis thereof by a portion of the safety latch (122) distanced from the needle opening (129).

Abstract translation: 装置（110）包括启动机构（20）和安全闩锁（122）。 激活机构可操作地展开针（116）以伸出外壳（112），针（116）具有纵向轴线。 安全闩锁（122）可移动地安装在壳体（112）上并且形成有针孔（129）以允许针116穿过。 安全闩锁（122）具有第一位置，其中针（116）对准以通过针开口（129）和第二位置，其中安全闩锁（122）相对于壳体（112）移动，使得 通过安全闩锁（122）远离针孔（129）的一部分，针（116）被阻止在平行于其纵向轴线的方向上的运动。

公开(公告)号：US20140330240A1

公开(公告)日：2014-11-06

申请号：US13886867

申请日：2013-05-03

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI ,  Reuven Y. FILMAN

IPC: A61M5/172

CPC classification number: A61M5/172 ,  A61M5/14244 ,  A61M5/16831 ,  A61M2005/16863 ,  A61M2205/70

Abstract: A status of a battery operated infuser may be detected by measuring a controlled input parameter. The measurement may be used to determine a magnitude of the input parameter and a parameter of the control. For example, control of power input to a motor may be by pulse density modulation. An integral of current over time may sever as a measure of current magnitude and pulse density. The result of the integral may be used to determine the status of the injector. The status may include normal functions for example start of pumping and/or malfunctions such as occlusion or drive disengagement.

Abstract translation: 可以通过测量受控的输入参数来检测电池操作的输注器的状态。 该测量可用于确定输入参数的大小和控制的参数。 例如，可以通过脉冲密度调制来控制对电动机的功率输入。 电流随时间的一个整体可能会被破坏为当前幅度和脉冲密度的量度。 积分的结果可用于确定喷射器的状态。 状态可以包括正常功能，例如开始泵送和/或故障，例如闭塞或驱动器分离。

公开(公告)号：US20160235915A1

公开(公告)日：2016-08-18

申请号：US15023038

申请日：2014-09-30

Applicant: MEDIMOP MEDICAL PROJECTS LTD.

Inventor： Oz CABIRI ,  Ran HEZKIAHU

IPC: A61M5/20 ,  A61M5/32

CPC classification number: A61M5/20 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/326 ,  A61M5/3287 ,  A61M5/425 ,  A61M2005/2006 ,  A61M2005/2013 ,  A61M2207/00 ,  Y10T29/49826

Abstract: The application concerns an autoinjector comprising a syringe, a driver for driving the plunger of the syringe and a stabilising adaptor for holding the injector on the skin of a patient. The stabilising adaptor has an adhesive base with a long axis to short axis ratio of at least 1.5 to 1. The syringe is orientated with its axis at an angle of between 60 and 120 degrees to the base during operation of the autoinjector.

Abstract translation: 该应用涉及包括注射器，用于驱动注射器的柱塞的驱动器和用于将注射器保持在患者皮肤上的稳定适配器的自动注射器。 稳定适配器具有长轴比与短轴比至少为1.5:1的粘合剂基底。在自动注射器操作期间，注射器的轴线定向成与基座成60至120度的角度。

公开(公告)号：US20160228652A1

公开(公告)日：2016-08-11

申请号：US15022991

申请日：2014-09-30

Applicant: MEDIMOP MEDICAL PROJECTS LTD.

Inventor： Oz CABIRI ,  Ran HEZKIAHU

IPC: A61M5/32 ,  A61M5/20

Abstract: An aspect of some embodiments of the present invention relates to a needle safety mechanism for an autoinjector. Optionally, an unshielded needle may be safeguarded when there is a change in resistance discharging the injector payload. The needle may optionally be safeguarded by retraction to a protected space and/or by deployment of a needle shield. Optionally the stress that prompts safeguarding the needle may include a torque and/or a linear stress.

Abstract translation: 本发明的一些实施例的一个方面涉及一种用于自动注射器的针安全机构。 可选地，当电阻放电喷射器有效载荷发生变化时，可以保护非屏蔽的针。 针可以可选地通过缩回到受保护的空间和/或通过展开针护罩来保护。 可选地，提示保护针的应力可包括扭矩和/或线性应力。

公开(公告)号：US20160193406A1

公开(公告)日：2016-07-07

申请号：US15069080

申请日：2016-03-14

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI

IPC: A61M5/162

CPC classification number: A61M5/1626 ,  A61M5/14244 ,  A61M5/158 ,  A61M5/3275 ,  A61M2005/1581 ,  F04C2270/0421

Abstract: A method and device are disclosed for preventing a needle stick hazard in the event of a collapse of a protective needle flap of a portable drug pump. The device may include a needle guide, a secure space and/or a shield. A point of a needle is optionally deflected into a secure space upon collapse of the protective flap. The space may optionally be shielded. Optionally, the support linking the needle to the pump may pivot and/or translate. Optionally, there may be an exposing position wherein the needle protrudes through an opening in the flap. Optionally, the opening may be non-circular.

公开(公告)号：US20150119797A1

公开(公告)日：2015-04-30

申请号：US14593041

申请日：2015-01-09

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI

IPC: A61M5/142 ,  A61M5/172 ,  A61M5/145

CPC classification number: A61M5/14248 ,  A61J1/1406 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/14566 ,  A61M5/158 ,  A61M5/172 ,  A61M5/283 ,  A61M5/3146 ,  A61M2005/14208 ,  A61M2005/14252 ,  A61M2005/14256 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2005/14573 ,  A61M2005/1581 ,  A61M2005/247 ,  A61M2005/2474 ,  A61M2205/123

Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

Abstract translation: 公开了将药物递送到接受者的方法和装置。 在一些实施方案中，递送装置可以开封含药物储存器。 在一些实施例中，输送速率可以被控制和/或可调节。 可选地，该装置可以是一次性的。 可选地，该装置可以具有低轮廓和/或可佩戴和/或可附接到接收者。 任选地，药物的排出和/或储存器的开封可以由平行于装置的底座移动的活塞驱动。 可选地，该装置可将皮下注射针释放到受体中。 任选地，皮下注射针的释放可以在与柱塞的移动方向不平行和/或正交的方向上。 任选地，在释放之前，皮下注射针可以通过密封针孔的针头开口隔膜保持在无菌状态。 任选地，在释放时，皮下注射针可以刺穿针头开口隔膜。

公开(公告)号：US20150032084A1

公开(公告)日：2015-01-29

申请号：US14510846

申请日：2014-10-09

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Oz CABIRI

IPC: A61M5/142 ,  A61M5/158 ,  A61M5/145

CPC classification number: A61M5/14248 ,  A61J1/1406 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/14566 ,  A61M5/158 ,  A61M5/172 ,  A61M5/283 ,  A61M5/3146 ,  A61M5/46 ,  A61M2005/14208 ,  A61M2005/14252 ,  A61M2005/14256 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2005/14573 ,  A61M2005/1581 ,  A61M2005/247 ,  A61M2005/2474 ,  A61M2205/123

Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

公开(公告)号：US20140174223A1

公开(公告)日：2014-06-26

申请号：US14193692

申请日：2014-02-28

Applicant: MEDIMOP Medical Projects Ltd.

Inventor： Yossi GROSS ,  Oz CABIRI

IPC: F16H25/12

CPC classification number: A61M5/31596 ,  A61M5/1413 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/1456 ,  A61M5/14566 ,  A61M5/158 ,  A61M5/16827 ,  A61M5/172 ,  A61M5/1723 ,  A61M5/3146 ,  A61M2005/14252 ,  A61M2005/1426 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2005/31518 ,  A61M2205/3523 ,  A61M2205/3569 ,  F16H25/12 ,  Y10T74/18576

Abstract: Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.

Abstract translation: 描述了用于向受试者施用物质的装置。 一个小瓶包含该物质，一个塞子设置在小瓶内并可滑动地连接到小瓶。 第一螺纹元件是（a）相对于小瓶可旋转，并且（b）在第一螺纹元件的旋转期间相对于小瓶在近端基本上不可移动。 第二螺纹元件螺纹连接到第一螺纹元件。 至少第二螺纹元件的远端相对于小瓶基本上不可旋转，并且第二螺纹元件的远端限定将第二螺纹元件联接到止动件的联接部分。 第一螺纹元件通过旋转线性地将止动件和至少第二螺纹元件的远端朝向小瓶的远端前进。 还描述了其它实施例。