METHODS AND BIOSENSORS FOR TUMOR DETECTION
    1.
    发明申请

    公开(公告)号:US20180087116A1

    公开(公告)日:2018-03-29

    申请号:US15818767

    申请日:2017-11-21

    IPC分类号: C12Q1/6886

    摘要: A method for tumor marker detection is disclosed. The method includes preparing a biosensor, forming a reference solution by adding the biosensor to a buffer solution, measuring a first fluorescence intensity of the reference solution, forming a mixture by adding a suspicious biological solution to the reference solution, measuring a second fluorescence intensity of the mixture, and detecting a presence of a tumor marker responsive to a difference between the first fluorescence intensity and the second fluorescence intensity. The biosensor preparation includes forming a functionalized nanomotor by functionalizing a nanomotor with an aptamer, forming a blocked functionalized nanomotor by blocking gaps between functionalized parts of the functionalized nanomotor with a blocking agent, and attaching a fluorescence probe to the blocked functionalized nanomotor.