公开(公告)号：US5733877A

公开(公告)日：1998-03-31

申请号：US503479

申请日：1995-07-18

申请人： Makoto Sato ,  Toshiyuki Kouzaki ,  Yoko Ishihara ,  Shigeaki Yoshina ,  Masanao Nakoshi ,  Tatsushi Maeda

发明人： Makoto Sato ,  Toshiyuki Kouzaki ,  Yoko Ishihara ,  Shigeaki Yoshina ,  Masanao Nakoshi ,  Tatsushi Maeda

IPC分类号： A61K9/107 ,  A61K38/00 ,  A61K38/22 ,  A61K38/23 ,  A61K47/12 ,  A61K47/24 ,  A61K47/28 ,  C07K14/575 ,  C07K14/585 ,  C07K14/63 ,  A61K38/02

CPC分类号： A61K38/23 ,  A61K38/2214 ,  A61K38/2278 ,  A61K47/12 ,  A61K47/24 ,  A61K9/0019 ,  A61K9/107 ,  Y10S514/938

摘要： A pharmaceutical composition is disclosed comprising a fat emulsion containing microspheres and having its electric charge adjusted to a negative value and a biologically active substance selected from the group consisting of a basic peptide and a basic protein, which biologically active substance is adsorbed to the microspheres in the fat emulsion. An acidic phospholipid, a fatty acid, a bilic acid and a salt of such substances is preferred as an agent for adjusting the electric charge of the fat emulsion. Motilin derivatives, vasoactive intestinal polypeptide derivatives and calcitonin are preferred biologically active substances.

摘要翻译： 公开了一种药物组合物，其包含含有微球并将其电荷调节至负值的脂肪乳剂和选自碱性肽和碱性蛋白质的生物活性物质，所述生物活性物质被吸附到微球体上 脂肪乳液。 优选酸性磷脂，脂肪酸，二胆酸和这些物质的盐作为调节脂肪乳剂电荷的试剂。 胃动素衍生物，血管活性肠多肽衍生物和降钙素是优选的生物活性物质。

公开(公告)号：US5308836A

公开(公告)日：1994-05-03

申请号：US116682

申请日：1993-09-07

申请人： Kiichi Sawai ,  Masayasu Kurono ,  Yasuaki Kondo ,  Makoto Sato ,  Toshiyuki Kouzaki

发明人： Kiichi Sawai ,  Masayasu Kurono ,  Yasuaki Kondo ,  Makoto Sato ,  Toshiyuki Kouzaki

IPC分类号： A61K9/08 ,  A61K38/22 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/26 ,  A61K47/36 ,  A61K47/42 ,  A61P1/00 ,  C07K1/00 ,  C07K14/00 ,  C07K14/575 ,  A61K37/24 ,  A61K37/36

CPC分类号： A61K38/2214

摘要： There is disclosed a pharmaceutical composition of stabilized [Leu.sup.13 ]-motilin-Hse. The composition comprises at least one of organic acids and salts thereof, as a first stabilizer, and pH thereof is adjusted in a range of 5.5-8.0. The composition may contain at least one of substances selected from saccharides, amino acids, proteins and salts thereof, as a second stabilizer. Conversion of [Leu.sup.13 ]-motilin-Hse into [Leu.sup.13 ]-motilin-Hse-lactone is suppressed by increasing pH value and deamidization in asparagine residue at 19-position is suppressed by the presence of the organic acid or salt thereof.

摘要翻译： 公开了一种稳定的[Leu13] -Motilin-Hse的药物组合物。 该组合物包含至少一种有机酸及其盐作为第一稳定剂，其pH调节在5.5-8.0的范围内。 该组合物可以含有选自糖，氨基酸，蛋白质和盐的至少一种物质作为第二稳定剂。 通过增加pH值可以抑制[Leu13] -motilin-Hse转化为[Leu13] - 肌动蛋白-Hse-内酯，并且通过存在有机酸或其盐来抑制在19位的天冬酰胺残基中的脱酰胺化。

公开(公告)号：US5279835A

公开(公告)日：1994-01-18

申请号：US906465

申请日：1992-06-30

申请人： Kiichi Sawai ,  Masayasu Kurono ,  Takahiko Mitani ,  Yasuaki Kondo ,  Makoto Sato ,  Yoshiro Ishiwata ,  Syoji Yokochi ,  Toshiyuki Kouzaki

发明人： Kiichi Sawai ,  Masayasu Kurono ,  Takahiko Mitani ,  Yasuaki Kondo ,  Makoto Sato ,  Yoshiro Ishiwata ,  Syoji Yokochi ,  Toshiyuki Kouzaki

IPC分类号： A61K9/20 ,  A61K31/28 ,  A61K31/80 ,  A61K47/02 ,  A61K47/26 ,  A61P43/00

CPC分类号： A61K31/80 ,  A61K31/28 ,  A61K9/2009 ,  A61K9/2018

摘要： A 3-oxygermylpropionic acid preparation is provided, which activates the action of 3-oxygermylpropionic acid having the general formula:[(O.sub.1/2).sub.3 GeCH.sub.2 CH.sub.2 COOH]n wherein n=an integer of at least 1 and is readily solubilized and disintegrated in vivo. The present preparation is manufactured by compression-molding at high pressure a composition comprising 3-oxygermylpropionic acid and two or more low-molecular substance of high solubility in water. The low-molecular substances are selected from the group consisting of white sugar, sorbitol, fructose, sucrose, glucose, lactose, mannitol and sodium chloride.

摘要翻译： 提供了3-氧基甲基丙酸制剂，其活化具有以下通式的3-氧基甲基丙酸的作用：（（O1 / 2）3GeCH2CH2COOH）n，其中n =至少为1的整数，并且在体内容易溶解和分解。 本制剂通过高压压缩成型制备，该组合物包含3-氧基甲基丙酸和两种或更多种在水中的高溶解度的低分子量物质。 低分子物质选自白糖，山梨糖醇，果糖，蔗糖，葡萄糖，乳糖，甘露醇和氯化钠。

公开(公告)号：US09625037B2

公开(公告)日：2017-04-18

申请号：US14726042

申请日：2015-05-29

申请人： Raymond Young ,  Marc Maloney ,  Roger Brown ,  Makoto Sato

发明人： Raymond Young ,  Marc Maloney ,  Roger Brown ,  Makoto Sato

IPC分类号： F16J15/02 ,  B65H45/02 ,  B60J10/00 ,  B60P3/34

CPC分类号： F16J15/027 ,  B60J10/00 ,  B60P3/34 ,  B65H45/02

摘要： A seal useful in sealing slide out rooms used in recreational vehicles. The seal may be used singularly or in pairs to straddle a wall through which the opening is located. A bulb is attached to the base in a cantilevered manner over the base. The bulb has an outer arcuate portion that is integrally joined to opposing sidewall portions. The sidewall portions extend into an inner wall that defines an enclosed space within the bulb portion. The bulb portion may also have a protrusion that can touch the base. A wiper extends from the base substantially co-linearly to the base and opposite the offsetting member. A locating leg extending from the base is movable between a first position and a second position. The first position has the locating leg perpendicular to the base and the second position places the locating leg parallel to the base.

公开(公告)号：US09245659B2

公开(公告)日：2016-01-26

申请号：US13937268

申请日：2013-07-09

申请人： Osamu Tsujii ,  Makoto Sato ,  Masahiko Okunuki ,  Satoshi Shimizu ,  Takashi Ogura

发明人： Osamu Tsujii ,  Makoto Sato ,  Masahiko Okunuki ,  Satoshi Shimizu ,  Takashi Ogura

IPC分类号： G21K1/04 ,  A61B6/06 ,  A61B6/00

CPC分类号： G21K1/04 ,  A61B6/06 ,  A61B6/4007 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/587 ,  G21K1/046 ,  H01J2235/068

摘要： An X-ray imaging apparatus is provided with a multi X-ray source and a collimator in which a plurality of slits for X-rays to pass through are two-dimensionally formed, the size and position of the slits being adjustable. A control unit, as a first control mode, controls the size and position of the slits to move an examination region in parallel, when an X-ray source is changed to a different X-ray source, such that the examination directions are parallel before and after the change. Also, the control unit, as a second control mode, controls the size and position of the slits to rotate the examination direction, when an X-ray source is changed to a different X-ray source, such that the center of the examination regions is the same before and after the change.

公开(公告)号：US20140076647A1

公开(公告)日：2014-03-20

申请号：US14009471

申请日：2012-01-27

申请人： Makoto Sato ,  Yujiro Sawasaki ,  Keiji Ito ,  Miyahito Hase ,  Hidehiko Makida ,  Makoto Morishima ,  Hiromasa Nishino ,  Yorikata Mizokami

发明人： Makoto Sato ,  Yujiro Sawasaki ,  Keiji Ito ,  Miyahito Hase ,  Hidehiko Makida ,  Makoto Morishima ,  Hiromasa Nishino ,  Yorikata Mizokami

IPC分类号： B66F9/075 ,  B62D33/06 ,  G21F3/00

CPC分类号： B62D33/06 ,  B62D33/0617 ,  B62D33/0621 ,  B66F9/07545 ,  B66F9/0759 ,  G21F3/00 ,  G21F5/14

摘要： A cabin 14 is formed as a casing body with a protection structure. The casing body is partitioned and separable from the vehicle body and has on a bottom side thereof support pillars 42 for secure attachment to the vehicle body 13 with restraint at least in planar coordinate directions.

摘要翻译： 机舱14形成为具有保护结构的壳体。 壳体主体被分隔并与车身分离，并且在其底侧具有支撑柱42，用于至少在平面坐标方向上以约束方式牢固地附接到车体13。

公开(公告)号：US08669584B2

公开(公告)日：2014-03-11

申请号：US13587699

申请日：2012-08-16

申请人： Makoto Sato ,  Satoshi Ota ,  Masakata Koseki

发明人： Makoto Sato ,  Satoshi Ota ,  Masakata Koseki

IPC分类号： H01L33/00

CPC分类号： H01L33/60 ,  H01L2933/0033

摘要： A light emitting device, comprises a LED chip, and a case having an accommodating recession accommodating the LED chip, wherein the light emitting device emits light from an opening portion of the accommodating recession, the case is monolithically formed by injection molding of a resin composition preparing by mixing fine grains of specular reflection material and glass fibers as diffusion reflecting material as fillers therein, an inner surface of a side wall portion of the case works as a reflector that reflects the light emitted from the LED chip so that the light is output from the opening portion, and a thickness of the side wall portion is selected to be smaller than an average length of the glass fibers.

摘要翻译： 一种发光装置，包括LED芯片和具有容纳LED芯片的容纳凹部的壳体，其中，所述发光装置从所述容纳凹部的开口部发射光，所述壳体通过树脂组合物的注射成型 通过将镜面反射材料和玻璃纤维的细晶粒作为扩散反射材料作为填料来制备，壳体的侧壁部分的内表面用作反射从LED芯片发射的光以使得光输出的反射器 从所述开口部开始，所述侧壁部的厚度选择为小于所述玻璃纤维的平均长度。

公开(公告)号：US08463917B2

公开(公告)日：2013-06-11

申请号：US10542221

申请日：2003-12-08

申请人： Kayo Sugimoto ,  Kazuyuki Ogawa ,  Yuji Takimoto ,  Makoto Sato

发明人： Kayo Sugimoto ,  Kazuyuki Ogawa ,  Yuji Takimoto ,  Makoto Sato

IPC分类号： G06F15/16

CPC分类号： H04N21/47217 ,  H04L65/602 ,  H04N7/17318 ,  H04N21/23106 ,  H04N21/6437 ,  H04N21/6587 ,  H04N21/8455

摘要： A communications system and method, an information processing apparatus and method, an information management apparatus and method, a recording medium and a program make it possible to efficiently and comfortably make use of contents, which are stored in one server, from a plurality of devices connected via a network. In a case in which the playing of content is stopped, bookmark information including a time stamp representing the stopped position of the content is stored in association with predetermined identification information. The bookmark information is available for various apparatuses transmitting the identification information. When playing the content from a position designated by the information from a predetermined apparatus, the time stamp included in the bookmark information is referred to and the playing of the content from the stopped position is started. The present invention can be applied to various apparatuses such as a personal computer, audio equipment, a PDA, a mobile phone and the like.

摘要翻译： 通信系统和方法，信息处理设备和方法，信息管理设备和方法，记录介质和程序使得可以从多个设备中高效且舒适地利用存储在一个服务器中的内容 通过网络连接。 在停止播放内容的情况下，与预定的识别信息相关联地存储包含表示内容的停止位置的时间戳的书签信息。 书签信息可用于发送识别信息的各种装置。 当从来自预定装置的信息指定的位置播放内容时，参考包括在书签信息中的时间标记，并且开始从停止位置播放内容。 本发明可以应用于个人计算机，音频设备，PDA，移动电话等各种装置。

公开(公告)号：US08426830B2

公开(公告)日：2013-04-23

申请号：US12613107

申请日：2009-11-05

申请人： Makoto Sato ,  Masahiro Kiyohara ,  Junichi Tashiro

发明人： Makoto Sato ,  Masahiro Kiyohara ,  Junichi Tashiro

IPC分类号： G21G4/00

CPC分类号： H01J37/3056 ,  H01J37/222 ,  H01J37/304 ,  H01J2237/221 ,  H01J2237/24507 ,  H01J2237/30416 ,  H01J2237/31745 ,  H01J2237/31749

摘要： A focused ion beam apparatus includes: a focused ion beam irradiating mechanism configured to irradiate a sample with a focused ion beam; a detector configured to detect a secondary charged particle generated by irradiating the sample with the focused beam; an image generating unit configured to generate an sample image of the sample; a processing area setting unit configured to set a processing area image including a plurality of pixels corresponding to positions of irradiation of the focused ion beam on the sample image; a position of irradiation setting unit configured to set coordinates of the pixels included in the processing area image; a beam setting unit configured to set a dose amount of the focused ion beam irradiated from the focused ion beam irradiating mechanism according to intensities; and an interpolating unit configured to perform an interpolating process on the processing area image.

摘要翻译： 聚焦离子束装置包括：聚焦离子束照射机构，被配置为用聚焦离子束照射样品; 检测器，被配置为检测通过用所述聚焦光束照射所述样品而产生的二次带电粒子; 图像生成单元，被配置为生成样本的样本图像; 处理区域设定单元，被配置为将包括与所述聚焦离子束的照射位置对应的多个像素的处理区域图像设置在所述样本图像上; 被配置为设置包括在处理区域图像中的像素的坐标的照射设置单元的位置; 光束设定单元，被配置为根据强度设定从所述聚焦离子束照射机构照射的聚焦离子束的剂量; 以及被配置为对所述处理区域图像执行内插处理的内插单元。

公开(公告)号：USRE43962E1

公开(公告)日：2013-02-05

申请号：US13370406

申请日：2012-02-10

申请人： Ichiro Sakamoto ,  Kenji Tomizawa ,  Hiraku Inoue ,  Makoto Sato

发明人： Ichiro Sakamoto ,  Kenji Tomizawa ,  Hiraku Inoue ,  Makoto Sato

IPC分类号： H04B1/44 ,  H04J3/16

CPC分类号： H04L12/40117 ,  G11B20/10527 ,  G11B27/034 ,  G11B27/105 ,  G11B27/3027 ,  G11B31/00 ,  G11B2220/2529 ,  G11B2220/2545 ,  H04L12/40058 ,  H04L12/40065

摘要： An object of the invention is to arrange so that the digital signal transmission between specific equipments connected with each other by the transmission line of a fixed standard can be performed securely and satisfactorily.When a digital signal destination is caused to receive a fixed digital signal sent out of a digital signal sender, the digital signal destination acquires at the request of the destination from the digital signal sender data on modes in which the digital signal sender is able to send out the digital signal, and a transmission mode of the digital signal is caused to be set by a command based on the acquired mode data from the digital signal destination. Moreover, when a digital signal destination is caused to receive a fixed digital signal sent out of a digital signal sender, a flag is added to the digital signal sent out of the digital signal sender, which indicates that the transmission rate is being adjusted based on the command from the digital signal destination.

摘要翻译： 本发明的一个目的是使得能够安全，令人满意地执行通过固定标准的传输线彼此连接的特定设备之间的数字信号传输。 当使数字信号目的地接收从数字信号发送器发出的固定数字信号时，数字信号目的地在数字信号发送器能够发送的模式下从数字信号发送器数据在目的地的请求处获取 输出数字信号，并且通过基于从数字信号目的地获取的模式数据的命令来设置数字信号的传输模式。 此外，当使数字信号目的地接收从数字信号发送器发出的固定数字信号时，将标志添加到从数字信号发送器发出的数字信号中，这表示传输速率正在基于 来自数字信号目的地的命令。