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公开(公告)号：US20140052250A1
公开(公告)日：2014-02-20
申请号：US13891677
申请日：2013-05-10
申请人： Anthony Wirtel, III , Mark Borden
发明人： Anthony Wirtel, III , Mark Borden
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/4202 , A61F2/4225 , A61F2/4241 , A61F2/441 , A61F2002/30062 , A61F2002/3008 , A61F2002/30133 , A61F2002/302 , A61F2002/30563 , A61F2002/30583 , A61F2002/30584 , A61F2002/30586 , A61F2002/30599 , A61F2002/30917 , A61F2002/444 , A61F2210/0004 , A61F2210/0085 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0019 , A61F2230/0065 , A61F2250/0003 , A61F2250/0063 , A61F2250/0098
摘要： Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems that include such devices, methods for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.
摘要翻译： 提供充气多室设备用于修复或更换脊椎椎间盘并分散相邻的椎骨元件。 还包括可用于关节置换装置缓冲系统中的缓冲装置。 还包括包括这种装置的装置和系统，用于制造这种装置的方法以及治疗需要这种装置的患者的方法。 实例还包括化妆品增补和恢复装置。
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公开(公告)号：US20070093912A1
公开(公告)日：2007-04-26
申请号：US11552244
申请日：2006-10-24
申请人： Mark Borden
发明人： Mark Borden
CPC分类号： A61F2/4455 , A61B17/0401 , A61B17/72 , A61B17/80 , A61B17/866 , A61B2017/00004 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2002/2835 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30069 , A61F2002/30199 , A61F2002/30622 , A61F2002/30784 , A61F2002/30925 , A61F2002/30957 , A61F2002/30968 , A61F2210/0004 , A61F2230/0063 , A61F2250/0023 , A61F2250/003 , A61F2310/00293 , A61F2310/00976 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/127 , A61L31/129 , A61L31/146 , A61L31/148 , Y10S606/907 , Y10S606/908
摘要： Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same.
摘要翻译： 具有改善的机械性能和/或降解特征的植入物，包括这种植入物的试剂盒，以及制备和使用该植入物的方法。
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公开(公告)号：US08460383B2
公开(公告)日：2013-06-11
申请号：US13473545
申请日：2012-05-16
申请人： Anthony Wirtel, III , Mark Borden
发明人： Anthony Wirtel, III , Mark Borden
CPC分类号： A61F2/442 , A61F2/4202 , A61F2/4225 , A61F2/4241 , A61F2/441 , A61F2002/30062 , A61F2002/3008 , A61F2002/30133 , A61F2002/302 , A61F2002/30563 , A61F2002/30583 , A61F2002/30584 , A61F2002/30586 , A61F2002/30599 , A61F2002/30917 , A61F2002/444 , A61F2210/0004 , A61F2210/0085 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0019 , A61F2230/0065 , A61F2250/0003 , A61F2250/0063 , A61F2250/0098
摘要： Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems that include such devices, methods for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.
摘要翻译： 提供充气多室设备用于修复或更换脊椎椎间盘并分散相邻的椎骨元件。 还包括可用于关节置换装置缓冲系统中的缓冲装置。 还包括包括这种装置的装置和系统，用于制造这种装置的方法以及治疗需要这种装置的患者的方法。 实例还包括化妆品增补和恢复装置。
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4.发明申请公开(公告)号：US20120232575A1
公开(公告)日：2012-09-13
申请号：US13473545
申请日：2012-05-16
申请人： Anthony Wirtel, III , Mark Borden
发明人： Anthony Wirtel, III , Mark Borden
IPC分类号： A61M29/02
CPC分类号： A61F2/442 , A61F2/4202 , A61F2/4225 , A61F2/4241 , A61F2/441 , A61F2002/30062 , A61F2002/3008 , A61F2002/30133 , A61F2002/302 , A61F2002/30563 , A61F2002/30583 , A61F2002/30584 , A61F2002/30586 , A61F2002/30599 , A61F2002/30917 , A61F2002/444 , A61F2210/0004 , A61F2210/0085 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0019 , A61F2230/0065 , A61F2250/0003 , A61F2250/0063 , A61F2250/0098
摘要： Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems that include such devices, methods for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.
摘要翻译： 提供充气多室设备用于修复或更换脊椎椎间盘并分散相邻的椎骨元件。 还包括可用于关节置换装置缓冲系统中的缓冲装置。 还包括包括这种装置的装置和系统，用于制造这种装置的方法以及治疗需要这种装置的患者的方法。 实例还包括化妆品增补和恢复装置。
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公开(公告)号：US08110007B2
公开(公告)日：2012-02-07
申请号：US12534094
申请日：2009-07-31
申请人： Mark Borden
发明人： Mark Borden
IPC分类号： A61F2/02
CPC分类号： A61F2/4455 , A61B17/0401 , A61B17/72 , A61B17/80 , A61B17/866 , A61B2017/00004 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2002/2835 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30069 , A61F2002/30199 , A61F2002/30622 , A61F2002/30784 , A61F2002/30925 , A61F2002/30957 , A61F2002/30968 , A61F2210/0004 , A61F2230/0063 , A61F2250/0023 , A61F2250/003 , A61F2310/00293 , A61F2310/00976 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/127 , A61L31/129 , A61L31/146 , A61L31/148 , Y10S606/907 , Y10S606/908
摘要： Implants, such as interbody spacers, fusion devices and bone grafts, are provided having improved mechanical properties and/or degradation profiles. Such implants include a three-dimensional scaffold formed from particles, such as microspheres, which may in some embodiments be resorbable or biodegradable and which may have at least two different degradation rates. In some embodiments, the scaffold may be elastomeric. The three-dimensional scaffold may be for example, porous or semi-porous. Also provided are kits including such implants, and methods of producing and using the same.
摘要翻译： 提供植入物，例如体间间隔物，融合装置和骨移植物，其具有改善的机械性能和/或降解特征。 这样的植入物包括由颗粒形成的三维支架，例如微球，其在一些实施方案中可再吸收或可生物降解，并且可具有至少两种不同的降解速率。 在一些实施方案中，支架可以是弹性体。 三维支架可以是例如多孔或半多孔的。 还提供了包括这种植入物的试剂盒，及其制备和使用方法。
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公开(公告)号：US20070202190A1
公开(公告)日：2007-08-30
申请号：US11362540
申请日：2006-02-27
申请人： Mark Borden
发明人： Mark Borden
摘要： The present invention provides novel methods of forming mineralized gelatin carriers from bone. The present invention further provides mineralized gelatin carriers themselves; bone products that include such mineralized gelatin carriers including DBM bone products; and kits that include mineralized gelatin carriers formed from bone. The present invention further provides methods for making DBM bone products, wherein both the DBM and a mineralized gelatin carrier for the DBM are derived independently from a bone lot.
摘要翻译： 本发明提供从骨形成矿化明胶载体的新方法。 本发明还提供矿化明胶载体本身; 骨产品包括这种矿化明胶载体，包括DBM骨产品; 和包括由骨形成的矿化明胶载体的试剂盒。 本发明还提供了制备DBM骨产品的方法，其中DBM和用于DBM的矿化明胶载体都独立于骨量衍生。
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公开(公告)号：US08394419B2
公开(公告)日：2013-03-12
申请号：US12985515
申请日：2011-01-06
申请人： Mark Borden
发明人： Mark Borden
CPC分类号： A61L27/365 , A61K35/32 , A61K38/39 , A61L27/222 , A61L27/3608 , A61L27/3683 , A61L27/3847 , A61L2430/02
摘要： The present invention provides novel methods of forming mineralized gelatin carriers from bone. The present invention further provides mineralized gelatin carriers themselves; bone products that include such mineralized gelatin carriers including DBM bone products; and kits that include mineralized gelatin carriers formed from bone. The present invention further provides methods for making DBM bone products, wherein both the DBM and a mineralized gelatin carrier for the DBM are derived independently from a bone lot.
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8.发明申请公开(公告)号：US20070288095A1
公开(公告)日：2007-12-13
申请号：US11761069
申请日：2007-06-11
申请人： Anthony Wirtel , Mark Borden
发明人： Anthony Wirtel , Mark Borden
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/4202 , A61F2/4225 , A61F2/4241 , A61F2/441 , A61F2002/30062 , A61F2002/3008 , A61F2002/30133 , A61F2002/302 , A61F2002/30563 , A61F2002/30583 , A61F2002/30584 , A61F2002/30586 , A61F2002/30599 , A61F2002/30917 , A61F2002/444 , A61F2210/0004 , A61F2210/0085 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0019 , A61F2230/0065 , A61F2250/0003 , A61F2250/0063 , A61F2250/0098
摘要： Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.
摘要翻译： 提供充气多室设备用于修复或更换脊椎椎间盘并分散相邻的椎骨元件。 还包括可用于关节置换装置缓冲系统中的缓冲装置。 进一步包括用于制造这种装置的试剂盒和系统，以及治疗需要这种装置的患者的方法。 实例还包括化妆品增补和恢复装置。
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公开(公告)号：US20070202191A1
公开(公告)日：2007-08-30
申请号：US11423839
申请日：2006-06-13
申请人： Mark Borden
发明人： Mark Borden
CPC分类号： A61L27/365 , A61K35/32 , A61K38/39 , A61L27/222 , A61L27/3608 , A61L27/3683 , A61L27/3847 , A61L2430/02
摘要： The present invention provides novel methods of forming mineralized gelatin carriers from bone. The present invention further provides mineralized gelatin carriers themselves; bone products that include such mineralized gelatin carriers including DBM bone products; and kits that include mineralized gelatin carriers formed from bone. The present invention further provides methods for making DBM bone products, wherein both the DBM and a mineralized gelatin carrier for the DBM are derived independently from a bone lot.
摘要翻译： 本发明提供从骨形成矿化明胶载体的新方法。 本发明还提供矿化明胶载体本身; 骨产品包括这种矿化明胶载体，包括DBM骨产品; 和包括由骨形成的矿化明胶载体的试剂盒。 本发明还提供了制备DBM骨产品的方法，其中DBM和用于DBM的矿化明胶载体都独立于骨量衍生。
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公开(公告)号：US07132110B2
公开(公告)日：2006-11-07
申请号：US10195671
申请日：2002-07-15
申请人： John F. Kay , Mark Borden , Richard Coulson , Edward King
发明人： John F. Kay , Mark Borden , Richard Coulson , Edward King
CPC分类号： A61L27/3691 , A61L27/3608 , A61L27/365 , A61L27/3683 , A61L27/3687 , A61L27/56 , A61L2430/02
摘要： An osteogenic composition is prepared by a process including the steps of subjecting demineralized bone to an extraction medium to produce an insoluble extraction product and a soluble extraction product, separating the insoluble extraction product and the soluble extraction product, drying the soluble extraction product to remove all or substantially all of the moisture in the soluble extraction product, and combining the dried soluble extraction product of step c) with demineralized bone particles. Preferably, the process does not involve heating.
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