Total synthesis of thaxtomin A analogues and their intermediates
    10.
    发明授权
    Total synthesis of thaxtomin A analogues and their intermediates 有权
    thaxtomin A类似物及其中间体的全合成

    公开(公告)号:US08993762B2

    公开(公告)日:2015-03-31

    申请号:US13840975

    申请日:2013-03-15

    IPC分类号: C07D403/06

    CPC分类号: C07D403/06

    摘要: Improved synthetic methods for the production of thaxtomin analogs, particularly thaxtomin A, and intermediates therefore such as substituted tryptophans and in particular, 4-nitro-L-tryptophan, and substituted phenyl acrylic acids are disclosed. Bioassays show that the synthetic thaxtomin A is not significantly different from the natural one in herbicidal activity.

    摘要翻译: 公开了用于生产thax​​tomin类似物,特别是thaxtomin A的改进的合成方法,因此例如取代的色氨酸,特别是4-硝基-L-色氨酸和取代的苯基丙烯酸的中间体。 生物测定表明,合成thaxtomin A与天然的除草活性没有显着差异。