公开(公告)号：US20120122791A1

公开(公告)日：2012-05-17

申请号：US13318312

申请日：2010-02-02

申请人： Masahiko Suzuki ,  Koichi Ueno ,  Nanami Muto

发明人： Masahiko Suzuki ,  Koichi Ueno ,  Nanami Muto

IPC分类号： A61K38/02 ,  A61P19/02 ,  A61P19/04 ,  C07K14/47

CPC分类号： A61L27/24 ,  A61L2400/06

摘要： Provided are a substrate for cartilage cultivation, which exhibits high safety and has a growth promoting effect on cartilage cells, and a method for cartilage regeneration treatment. The substrate for cartilage cultivation containing artificial collagen, in particular, an artificial collagen aqueous solution has a growth promoting effect on cartilage cells. A cartilage regeneration effect is obtained by the intraarticular injection of the substrate in and around a cartilage defect site.

摘要翻译： 本发明提供一种软骨培养用基材，其具有高的安全性，对软骨细胞具有生长促进作用，以及软骨再生处理方法。 含有人造胶原的软骨培养基质，特别是人造胶原水溶液对软骨细胞具有生长促进作用。 通过在软骨缺损部位及其周围的关节内注射基质获得软骨再生效果。

公开(公告)号：US20120083009A1

公开(公告)日：2012-04-05

申请号：US13290181

申请日：2011-11-07

申请人： Masahiko Suzuki ,  Fumie Aosai ,  Koichi Ueno

发明人： Masahiko Suzuki ,  Fumie Aosai ,  Koichi Ueno

IPC分类号： G01N33/566

CPC分类号： G01N33/564 ,  C07K16/18 ,  G01N2800/102 ,  G01N2800/52 ,  G01N2800/56

摘要： To evaluate the prognosis of rheumatoid arthritis based on the evaluation of the disease severity of the patient to select a treatment method suitable for each rheumatoid arthritis patients, and to measure HSC71 protein levels of the patients before and after the administrations of therapeutic agents to determine the efficacy of various therapeutic agents for each of rheumatoid arthritis patients and to use thereof as a remedy for preventing onset and progression of rheumatoid arthritis.

摘要翻译： 根据对患者疾病严重程度的评估来评估类风湿性关节炎的预后，以选择适合于每种类风湿性关节炎患者的治疗方法，并测量治疗剂施用前后患者的HSC71蛋白水平，以确定 各种治疗剂对于类风湿关节炎患者中的每一种的功效以及其作为预防类风湿性关节炎发作和进展的补救措施。

公开(公告)号：US20090176245A1

公开(公告)日：2009-07-09

申请号：US12281191

申请日：2007-03-01

申请人： Masahiko Suzuki ,  Fumie Aosai ,  Koichi Ueno

发明人： Masahiko Suzuki ,  Fumie Aosai ,  Koichi Ueno

IPC分类号： G01N33/53

CPC分类号： G01N33/564 ,  C07K16/18 ,  G01N2800/102 ,  G01N2800/52 ,  G01N2800/56

摘要： It is intended to evaluate the prognosis of rheumatoid arthritis based on the evaluation of the disease severity of the patient to select a treatment method suitable for each rheumatoid arthritis patients, and to measure HSC71 protein levels of the patients before and after the administrations of therapeutic agents to determine the efficacy of various therapeutic agents for each of rheumatoid arthritis patients, and to use thereof as a remedy for preventing onset and progression of rheumatoid arthritis. It has been revealed that whether HSC71 (heat shock cognate protein 71), which is a member of the heat shock protein 70 family, shows any difference in expression between rheumatoid arthritis patients and healthy subjects. In the case where the HSC71 protein is accelerated in a rheumatoid arthritis patient the HSC71 concentrations in the serum, synovial fluid, serebrospinal fluid, urine, saliva and sputum of the patient are measured to thereby examine the disease severity of rheumatoid arthritis. Based thereon, the prognosis of the rheumatoid arthritis is evaluated and a method suitable for the patient is selected. HSC71 protein levels are measured before and after the administration of therapeutic agents to a rheumatoid arthritis patient and the efficacy of the therapeutic agents are determined. Further, Use as a remedy or preventing the onset and progression of rheumatoid arthritis is intended.

摘要翻译： 旨在通过评估患者的疾病严重程度来评估类风湿性关节炎的预后，以选择适合于每种类风湿性关节炎患者的治疗方法，并测量治疗剂施用前后患者的HSC71蛋白水平 以确定各种治疗剂对于类风湿关节炎患者的功效，并将其用作预防类风湿性关节炎发病和进展的补救措施。 已经显示，作为热休克蛋白70家族的成员的HSC71（热休克同源蛋白71）是否表现出类风湿性关节炎患者和健康受试者之间的表达的任何差异。 在HSC71蛋白在类风湿关节炎患者中加速的情况下，测量患者血清，滑液，脊髓液，尿液，唾液和痰中的HSC71浓度，从而检测类风湿性关节炎的疾病严重程度。 基于此，评估类风湿性关节炎的预后，并选择适合于患者的方法。 在向类风湿性关节炎患者施用治疗剂之前和之后测量HSC71蛋白水平，并测定治疗剂的功效。 此外，意图是用作补救剂或预防类风湿性关节炎的发作和进展。

公开(公告)号：US08305397B2

公开(公告)日：2012-11-06

申请号：US12311641

申请日：2007-08-01

申请人： Koichi Ueno ,  Masanori Katsura ,  Kazuyuki Watanabe ,  Yasuhiro Kobayashi ,  Kiyoyuki Tanaka

发明人： Koichi Ueno ,  Masanori Katsura ,  Kazuyuki Watanabe ,  Yasuhiro Kobayashi ,  Kiyoyuki Tanaka

IPC分类号： G06T17/00 ,  G09G5/00 ,  G03F3/08 ,  H04N1/46 ,  H04N5/21 ,  G06K9/40 ,  G06K9/36 ,  H04N5/00 ,  H04N9/64 ,  H04N5/52

CPC分类号： G06T5/002 ,  G06T5/004 ,  G06T2207/20192 ,  H04N5/142 ,  H04N5/208

摘要： A noise removing filter removes noise from an input image and an edge component extracting unit extracts edge components. The edge components are extracted by calculating a difference between the input image and a smoothed image, which is obtained by smoothing the input image in a smoothed image generating portion. An edge component comparing unit compares the extracted edge components with a threshold value and a sum calculating unit calculates the sum of the edge components greater than the threshold value. A control circuit determines the enhancement degree of the edges based on the sum and averaged luminance of the input image calculated by an average luminance calculating unit. An enhancement degree adjustment unit adjusts the determined enhancement degree, and an edge component enhancement unit enhances the edge components based on this enhancement degree and adds it to the input image to perform edge enhancement processing.

摘要翻译： 噪声去除滤波器从输入图像中去除噪声，并且边缘分量提取单元提取边缘分量。 通过计算输入图像和平滑图像之间的差异来提取边缘分量，该平滑化图像通过平滑平滑图像生成部分中的输入图像而获得。 边缘分量比较单元将所提取的边缘分量与阈值进行比较，并且和计算单元计算大于阈值的边缘分量的和。 控制电路基于由平均亮度计算单元计算的输入图像的和和平均亮度来确定边缘的增强度。 增强度调整单元调整所确定的增强度，并且边缘分量增强单元基于该增强度增强边缘分量，并将其添加到输入图像以执行边缘增强处理。

公开(公告)号：USD287473S

公开(公告)日：1986-12-30

申请号：US647472

申请日：1984-09-05

申请人： Koichi Ueno

设计人： Koichi Ueno

公开(公告)号：US20060245103A1

公开(公告)日：2006-11-02

申请号：US11167469

申请日：2005-06-28

申请人： Koichi Ueno ,  Seiki Morita

发明人： Koichi Ueno ,  Seiki Morita

IPC分类号： G11B5/09

CPC分类号： G06F11/1076 ,  G06F2211/1009

摘要： The storage device system has a storage device to which system information related to the storage device system is written, and a determination unit determining the presence and absence of system information errors before operation based on system information written to the storage device is conducted. When an error is determined as a result of the determination of the system information written to one storage device of a plurality of storage devices, storage device can be closed, and system information written to another storage device is determined for the presence and absence of errors.

摘要翻译： 存储装置系统具有与存储装置系统相关的系统信息被写入的存储装置，并且确定单元基于写入存储装置的系统信息来确定操作之前是否存在系统信息错误。 作为确定写入多个存储装置的一个存储装置的系统信息的结果，当确定了错误时，可以关闭存储装置，并且确定写入另一个存储装置的系统信息是否存在错误 。

公开(公告)号：US20050116384A1

公开(公告)日：2005-06-02

申请号：US10999193

申请日：2004-11-30

申请人： Hiromi Hyuga ,  Koichi Ueno ,  Nobuyoshi Baba ,  Daiichiro Kawashima

发明人： Hiromi Hyuga ,  Koichi Ueno ,  Nobuyoshi Baba ,  Daiichiro Kawashima

IPC分类号： B05D7/02 ,  B29C37/00 ,  B29C45/14 ,  B29C45/16 ,  B29C45/26 ,  B29L9/00 ,  B32B3/26

CPC分类号： B29C45/14065 ,  B29C37/0028 ,  B29C45/1679 ,  B29C2045/1687

摘要： A method for molding an in-mold coating product including a substrate and a coating formed on a surface of the substrate. A first mold including a fixed mold piece is closed to form a substrate cavity therein. The substrate cavity is charged with a resin to form the substrate with a seal projection formed near the parting line of the first mold. Then, a second mold, which uses the fixed mold piece of the first mold, is closed with the substrate arranged on the fixed mold piece to form a coating cavity therein. The second mold deforms the seal projection so that when a coating material is charged into the coating cavity, the coating material does not leak out toward the parting line of the second mold.

摘要翻译： 一种成型模内涂料的方法，包括在基材表面上形成的基材和涂层。 包括固定模具的第一模具被封闭以在其中形成衬底空腔。 用树脂填充衬底空腔以形成衬底，其中密封突起形成在第一模具的分型线附近。 然后，使用第一模具的固定模具片的第二模具用布置在固定模具上的基板封闭，以在其中形成涂覆空腔。 第二模具使密封突起变形，使得当涂料被填充到涂层腔中时，涂层材料不会朝向第二模具的分型线泄漏。

公开(公告)号：US08326939B2

公开(公告)日：2012-12-04

申请号：US12068088

申请日：2008-02-01

申请人： Koichi Ueno ,  Koji Nagata ,  Yusuke Nonaka

发明人： Koichi Ueno ,  Koji Nagata ,  Yusuke Nonaka

IPC分类号： G06F15/16

CPC分类号： G06F3/0647 ,  G06F3/0604 ,  G06F3/067 ,  G06F11/2092

摘要： A first storage system that has a first storage device comprises a first interface device that is connected to a second interface device that a second storage system has. A first controller of the first storage system reads system information elements of first system information (information relating to the constitution and control of the first storage system) from a first system area (a storage area that is not provided for the host of the first storage device) and transfers the system information elements or modified system information elements to the second storage system via the first interface device. The system information elements are recorded in a second system area in a second storage device that the second storage system has.

摘要翻译： 具有第一存储设备的第一存储系统包括连接到第二存储系统具有的第二接口设备的第一接口设备。 第一存储系统的第一控制器从第一系统区域（不为第一存储器的主机提供的存储区域）读取第一系统信息的系统信息（与第一存储系统的结构和控制有关的信息） 设备），并且经由第一接口设备将系统信息元素或修改的系统信息元素传送到第二存储系统。 系统信息元素被记录在第二存储系统所具有的第二存储装置中的第二系统区域中。

公开(公告)号：US5813250A

公开(公告)日：1998-09-29

申请号：US823165

申请日：1997-03-25

申请人： Koichi Ueno ,  Kenichiro Mitsuhashi

发明人： Koichi Ueno ,  Kenichiro Mitsuhashi

IPC分类号： F25J1/02 ,  F25J3/00 ,  F28D9/00

CPC分类号： F28D9/0093 ,  F25J1/0022 ,  F25J1/0052 ,  F25J1/0055 ,  F25J1/0216 ,  F25J1/0262 ,  F25J1/0272 ,  F25J1/0292 ,  F25J5/002 ,  F28D9/0006 ,  F25J2220/64 ,  F25J2240/40 ,  F25J2290/10 ,  F25J2290/32 ,  F25J2290/50 ,  Y10S62/903

摘要： A heat exchanging device of a gas liquefying plant including a precooling section with a single component refrigerant system, a liquefying section with a multi-component refrigerant system where the liquefying section has an array of plate-fin type heat exchangers installed in a vertical orientation with their hot end being set at an upper part of a refrigerating container and its cold end being set at a lower part of the refrigerating container. The plate-fin type heat exchangers are divided into predetermined temperature cooling ranges arranged in a vertical orientation with the hottest end being placed at the upper part and the coldest end being placed at the lower part of the refrigerating container.

摘要翻译： 一种气体液化装置的热交换装置，包括具有单一部件制冷剂系统的预冷却部分，具有多组分制冷剂系统的液化部分，其中液化部分具有垂直方向安装的板翅式热交换器阵列， 其热端设置在制冷容器的上部，其冷端设置在制冷容器的下部。 板翅式热交换器被分为以垂直方向布置的预定温度冷却范围，最热端放置在上部，最冷端位于冷藏集装箱的下部。

公开(公告)号：US5341769A

公开(公告)日：1994-08-30

申请号：US989375

申请日：1992-12-11

申请人： Koichi Ueno ,  Akio Tsukamoto ,  Tamotsu Tori ,  Hiroo Nishimura ,  Keizo Konishi ,  Fukuzo Harada

发明人： Koichi Ueno ,  Akio Tsukamoto ,  Tamotsu Tori ,  Hiroo Nishimura ,  Keizo Konishi ,  Fukuzo Harada

IPC分类号： F28D3/02 ,  F17C9/02 ,  F28D7/10 ,  F28F1/14 ,  F28F1/40 ,  F28F13/06 ,  F28F19/00 ,  F22B23/06

CPC分类号： F28D7/106 ,  F17C9/02 ,  F28D3/02 ,  F28D3/04 ,  F28F1/14 ,  F28F1/40 ,  F28F13/06 ,  F28F19/006 ,  F17C2205/0358 ,  F17C2221/033 ,  F17C2223/0161 ,  F17C2223/033 ,  F17C2225/0123 ,  F17C2225/036 ,  F17C2227/0397 ,  F28D2021/0064

摘要： A vaporizer for liquefied natural gas which prevents the heat exchanger tubes from being extremely cooled, without reducing the vaporizing efficiency. The vaporizer is characterized in that each of the heat exchanger tubes connecting the lower header and upper header contains a pipe for liquefied natural gas in a certain region from its end near the inlet, said pipe having on its outer surface fins which are in pressure contact with the inner surface of the heat exchanger tube, and the heat exchanger tube is in direct contact with the natural gas in its region near the outlet and beyond the region in which the pipe for liquefied natural gas lies.

摘要翻译： 一种用于液化天然气的蒸发器，其防止热交换器管被极度冷却，而不降低蒸发效率。 蒸发器的特征在于，连接下集管和上集管的每个热交换器管从其入口附近的一端的一定区域中包含用于液化天然气的管，所述管在其外表面上具有压力接触的翅片 与热交换器管的内表面，并且热交换器管直接与其出口附近的天然气直接接触，并且超过液化天然气管所在的区域。