公开(公告)号：US06660383B2

公开(公告)日：2003-12-09

申请号：US09766800

申请日：2001-01-22

申请人： Masahiro Toyoda ,  Yoshio Sohda ,  Yukinori Kude ,  Tsutomu Kihara ,  Osamu Katou

发明人： Masahiro Toyoda ,  Yoshio Sohda ,  Yukinori Kude ,  Tsutomu Kihara ,  Osamu Katou

IPC分类号： B32B9100

CPC分类号： D01F11/16 ,  D01F9/12 ,  Y10S502/526 ,  Y10T428/2918 ,  Y10T428/30 ,  Y10T442/2984 ,  Y10T442/63

摘要： Carbon fiber including graphitized fiber is processed electrochemically in an acidic solution for a time sufficient to run a layer reaction such that the reaction extends to the inside of the fiber and thereafter, as required, heat-treated accurately at 100° C. or more to expand layer spacing to form multifibrous carbon fiber, with which hydrogen is brought into contact, adsorbing hydrogen in the inside of the multifibrous carbon fiber.

摘要翻译： 包括石墨化纤维在内的碳纤维在酸性溶液中电化学处理足以进行层反应的时间，使得反应延伸到纤维内部，之后根据需要在100℃以上精确地热处理至 扩大层间距，形成多纤碳纤维，氢气与其接触，在多纤碳纤维内吸附氢。

公开(公告)号：US08343085B2

公开(公告)日：2013-01-01

申请号：US12680298

申请日：2009-12-15

申请人： Masahiro Toyoda ,  Satoshi Takeuchi

发明人： Masahiro Toyoda ,  Satoshi Takeuchi

IPC分类号： A61M37/00

CPC分类号： A61M1/3643 ,  A61M1/3626 ,  A61M1/3644 ,  A61M1/3646 ,  A61M1/3649

摘要： The present invention relates to a blood purification apparatus for extracorporeally circulating the blood of a patient so as to purify the blood for medical treatment incorporating a dialyzer and a method for priming the blood purification apparatus, wherein the present invention provides a blood purification apparatus and its priming method which can simply and easily automate the priming operation and also can surely and smoothly perform the bubble purging of the dialyzer.

摘要翻译： 本发明涉及一种血液净化装置，其用于体外循环患者的血液，以净化包含透析器的医疗用血液，以及用于引导血液净化装置的方法，其中本发明提供一种血液净化装置及其 起动方法，其可以简单且容易地自动化起动操作，并且还可以可靠和平稳地执行透析器的气泡吹扫。

公开(公告)号：US20120045384A1

公开(公告)日：2012-02-23

申请号：US13266295

申请日：2010-05-01

申请人： Kazuo Muramatsu ,  Masahiro Toyoda

发明人： Kazuo Muramatsu ,  Masahiro Toyoda

IPC分类号： C01B31/02 ,  C01B31/10 ,  B02C19/00 ,  C01B31/00

CPC分类号： H01M4/587 ,  C01B31/00 ,  C01B31/04 ,  C01B32/00 ,  C01B32/20 ,  C04B35/52 ,  C04B35/522 ,  C04B35/524 ,  C04B35/6267 ,  C04B35/6455 ,  C04B38/0022 ,  C04B2111/00853 ,  C04B2235/6562 ,  C04B2235/767 ,  C04B2235/77 ,  Y10T428/2982 ,  C04B38/0054

摘要： (Problem)A porous carbon material having excellent graphite crystallinity, good carrier mobility and proper porosity, a porous carbon material having edges of carbon hexagonal planes located on outer surfaces of particle and structure, and flaky graphite being similar to graphene are produced.(Means to Solve)By subjecting a carbon material, in which a closed-pore-ratio and an amount of remaining hydrogen in the material are set to be within a proper range, to hot isostatic pressing treatment, a vapor phase growth reaction of graphite is generated in closed pores as nuclei using hydrogen and hydrocarbon generated from the carbon material, thereby producing a large amount of targeted porous carbon material at low cost. Flaky graphite being similar to graphene is produced by applying physical impact to the obtained porous carbon material or by generating a graphite intercalation compound using the porous carbon material as a host and then quickly heating the compound.

摘要翻译： （问题）制造具有优异的石墨结晶性，良好的载流子迁移率和适当孔隙率的多孔碳材料，具有位于颗粒和结构的外表面上的碳六角形平面边缘的多孔碳材料和类似于石墨烯的片状石墨。 （解决手段）通过将材料中的闭孔比和剩余氢量设定在适当范围内的碳材料进行热等静压处理，将石墨的气相生长反应 在密闭孔中产生，使用由碳材料生成的氢和烃产生的核，从而以低成本生产大量的目标多孔碳材料。 与石墨烯类似的片状石墨通过对所得多孔碳材料进行物理冲击或通过使用多孔碳材料作为主体产生石墨插层化合物，然后快速加热该化合物来生产。

公开(公告)号：US20080103427A1

公开(公告)日：2008-05-01

申请号：US11863493

申请日：2007-09-28

申请人： Masahiro Toyoda ,  Tomoya Murakami

发明人： Masahiro Toyoda ,  Tomoya Murakami

IPC分类号： A61M1/14

CPC分类号： A61M1/16 ,  A61M1/1613 ,  A61M1/3609 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3658 ,  A61M2205/3313 ,  A61M2205/50 ,  A61M2230/207

摘要： A blood purification device capable of performing an ideal blood purification treatment which accounts for blood recirculation is provided. That is, a blood purification device is furnished with a blood circuit containing an arterial blood circuit and a venous blood circuit for circulating blood outside the body, a dialyzer for purifying blood flowing in the blood circuit, hematocrit sensors for measuring the hematocrit value of blood circulating outside the body in the blood circuit, and a recirculation rate derivation means for obtaining a recirculation rate, and further provided with a true value derivation means for obtaining a patient's true hematocrit value based on the recirculation rate obtained by the recirculation rate derivation means.

摘要翻译： 提供能够进行考虑血液再循环的理想的血液净化处理的血液净化装置。 也就是说，血液净化装置配备有包含动脉血回路的血液回路和用于使体外循环血液的静脉血回路，用于净化血液回路中流动的血液的透析器，用于测量血液的血细胞比容值的血细胞比容传感器 在血液循环体外循环，以及用于获得再循环率的再循环速率导出装置，并且还具有真值推定装置，用于根据再循环速率导出装置获得的再循环速度获得患者的真实血细胞比容值。

公开(公告)号：US20060226079A1

公开(公告)日：2006-10-12

申请号：US11278745

申请日：2006-04-05

申请人： Yoshihiro Mori ,  Masahiro Toyoda

发明人： Yoshihiro Mori ,  Masahiro Toyoda

IPC分类号： B01D65/00

CPC分类号： A61M1/16 ,  A61M1/1611 ,  A61M1/1613 ,  A61M1/341 ,  A61M2205/52 ,  A61M2230/207

摘要： A hemodialysis apparatus includes a dialyzing device, a measuring device and a calculation device. The dialyzing device dialyzes and ultrafiltrates blood of a patient circulating extracorporeally to perform hemodialysis treatment. The measuring device measures a variation rate of a body weight of the patient and a variation rate of a predetermined blood benchmark during the hemodialysis treatment using the dialyzing device. The calculation device calculates, during the hemodialysis treatment, a parameter relating the variation rate of the body weight and the variation rate of the predetermined blood benchmark to each other, and correlating to a dry weight of the patient.

摘要翻译： 血液透析装置包括透析装置，测量装置和计算装置。 透析装置透析和超滤体外循环的患者的血液进行血液透析治疗。 测量装置测量使用透析装置的血液透析治疗期间患者体重的变化率和预定血液基准的变化率。 计算装置在血液透析治疗期间，计算将体重的变化率与预定血液基准的变化率相关联的参数，并与患者的干重相关联。

公开(公告)号：US4902929A

公开(公告)日：1990-02-20

申请号：US190716

申请日：1988-05-06

申请人： Masahiro Toyoda ,  Katsuhiko Tanaka

发明人： Masahiro Toyoda ,  Katsuhiko Tanaka

IPC分类号： C09K11/02 ,  H05B33/04 ,  H05B33/20

CPC分类号： C09K11/025 ,  H05B33/04 ,  H05B33/20 ,  Y10T428/2991

摘要： An electroluminescent device comprises a luminous layer containing electroluminescent particles each covered with a moisture-proof film, which is formed by polymer, having network structure obtained by hydrolyzing metal alkoxide and causing polycondensation reaction. The moisture-proof film may contain pigment, or a film containing pigment may be formed to cover the electroluminescent particle.

摘要翻译： 电致发光器件包括含有电致发光粒子的发光层，每个电致发光粒子都被由聚合物形成的防湿膜覆盖，该网状结构通过水解金属醇盐而引起缩聚反应。 防湿膜可以含有颜料，或者可以形成含有颜料的膜以覆盖电致发光颗粒。

公开(公告)号：US07931610B2

公开(公告)日：2011-04-26

申请号：US12174742

申请日：2008-07-17

申请人： Tomoya Murakami ,  Masahiro Toyoda ,  Akari Agata

发明人： Tomoya Murakami ,  Masahiro Toyoda ,  Akari Agata

IPC分类号： C02F1/44 ,  A61M37/00

CPC分类号： A61M1/3653 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3658

摘要： A blood purification apparatus that can make the specific peak to be imparted to the blood more distinct, and therefore can detect blood recirculation reliably and precisely, is presented. It contains a blood circuit route, a blood pump, a dialyzer, dialysate introduction and discharge lines, a duplex pump, a pressurizing pump, a blood concentration means, and detection means that detect the specific peak imparted by the blood concentration means. The blood concentration means is configured to have an atmosphere release line, the tip of which is open to the atmosphere, that extends from between the pressurizing pump and the duplex pump in the dialysate discharge line, and to have an electromagnetic valve that can open or close the atmosphere release line. The electromagnetic valve opens the atmosphere release line to impart the specific peak by rapidly concentrating the blood flowing in the dialyzer for a short period of time.

摘要翻译： 可以使血液净化装置能够使特定的峰值赋予血液更加清晰，因此可以可靠且精确地检测血液循环。 它包含血液回路，血液泵，透析器，透析液引入和排出管线，双相泵，加压泵，血液浓缩装置和检测由血液浓度装置赋予的特定峰值的检测装置。 血液浓度装置被配置为具有气体释放管线，其顶端向大气开放，其从透析液排出管线中的加压泵和双相泵之间延伸，并且具有能够打开的电磁阀或 关闭气氛释放线。 电磁阀打开大气释放线，以通过快速浓缩在透析器中流动的血液短时间来赋予特定峰值。

公开(公告)号：US07537687B2

公开(公告)日：2009-05-26

申请号：US11246385

申请日：2005-10-07

申请人： Masahiro Toyoda ,  Yasushi Takakuwa

发明人： Masahiro Toyoda ,  Yasushi Takakuwa

IPC分类号： C02F1/44 ,  A61M1/16

CPC分类号： A61M1/367 ,  A61M1/3656 ,  A61M1/3669 ,  A61M2205/13

摘要： A hemodialysis device includes a hemodialysis device main body including an arterial blood circuit, venous blood circuit, blood pump, dialyzer, dialysate inlet and outlet lines, voltage adding device, electric potential measuring device, and monitoring device monitoring the needle when it is detached from the patient based on an electric potential measured by the electric potential measuring device. One electrode of the voltage adding device is attached between an arterial blood needle in the arterial blood circuit and the pump, and another electrode is attached to the dialysate outlet line. The hemodialysis device allows the precise detection of a needle that is detached from a patient taking a blood hemodialysis treatment by monitoring a voltage difference at a predetermined position while providing voltage to the blood flowing in the blood circuit. The device also allows the suppression of an increase in production cost for a disposable blood circuit.

摘要翻译： 血液透析装置包括：血液透析装置主体，包括动脉血液回路，静脉血液回路，血液泵，透析器，透析液入口和出口管线，加压装置，电位测量装置，以及监测装置，当针脱离时 所述患者基于由所述电位测量装置测量的电位。 电压添加装置的一个电极被安装在动脉血液回路中的动脉血针和泵之间，另一个电极连接到透析液出口管线。 血液透析装置允许通过在向血液回路中流动的血液提供电压的同时监视预定位置处的电压差来精确检测与进行血液透析治疗的患者分离的针。 该装置还允许抑制一次性血液回路的生产成本的增加。

公开(公告)号：US20070108129A1

公开(公告)日：2007-05-17

申请号：US11556790

申请日：2006-11-06

申请人： Yoshihiro Mori ,  Masahiro Toyoda

发明人： Yoshihiro Mori ,  Masahiro Toyoda

IPC分类号： B01D61/30

CPC分类号： A61M1/16 ,  A61M1/1613 ,  A61M1/361 ,  A61M2205/3393 ,  A61M2205/52

摘要： A hemodialysis apparatus includes a dialysis device, a detecting device, an evaluation device and a memory device. The dialysis device dialyzes and ultrafiltrates blood of a patient according to an ultrafiltration volume based on an estimated dry weight while performing hemodialysis treatment on the blood circulating extracorporeally. The detecting device obtains time series data by measuring a parameter related to concentration of the blood circulating extracorporeally at a plurality of points in time series in a process of the hemodialysis treatment by the dialysis device. The evaluation device evaluates appropriateness of the hemodialysis treatment by evaluating whether the estimated dry weight approximates to a dry weight after the hemodialysis treatment by the dialysis device. The memory device stores a plurality of time series data when the hemodialysis treatment is evaluated to be appropriate by the evaluation device.

摘要翻译： 血液透析装置包括透析装置，检测装置，评价装置和存储装置。 所述透析装置在对体外循环进行血液透析治疗的同时，根据基于估计干重的超滤体积透析和超滤患者的血液。 检测装置通过在透析装置进行血液透析处理的过程中，以时间序列的方式，在体外多次测量与血液循环的浓度相关的参数来获取时间序列数据。 评价装置通过评价透析装置进行血液透析处理后的估计干重近似于干重来评价血液透析治疗的适当性。 当通过评估装置评估血液透析治疗以适合时，存储装置存储多个时间序列数据。

公开(公告)号：US20130270119A1

公开(公告)日：2013-10-17

申请号：US13989054

申请日：2011-11-28

申请人： Takuya Wada ,  Masahiro Toyoda

发明人： Takuya Wada ,  Masahiro Toyoda

IPC分类号： C01B31/04 ,  C25D5/54

CPC分类号： C25D5/54 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/184 ,  C01B32/22 ,  C01B32/225 ,  C01P2002/72 ,  C25B1/00

摘要： Provided are a carbonaceous material with less variation in facing relation between graphenes, a process for producing the carbonaceous material, a process for producing exfoliated graphite that enables easy and massive production of graphite flaked more than ever, and the exfoliated graphite. The carbonaceous material contains an intercalation substance intercalated between graphenes of a graphene stack and is expanded graphite which shows in an XRD pattern respective peaks in 7-12° and 18-24° ranges of 2θ and in which a peak in 25-27° range has a smaller height than that in 18-24° range and a half width of the peak in 7-12° range is 4 degrees or less. The process for producing the carbonaceous material includes immersing at least a portion of sheet-like graphite or sheet-like pre-expanded graphite into an aqueous electrolyte solution to subject the graphite to an electrochemical treatment. The process for producing exfoliated graphite includes the step of applying an exfoliation force to the carbonaceous material to obtain exfoliated graphite. The exfoliated graphite is obtained by this production process.

摘要翻译： 提供了石墨烯之间的面对关系变化较小的碳质材料，碳质材料的制造方法，能够容易地大量生产比以往更大的石墨的剥离石墨的制造方法和剥离石墨。 含碳材料包含插入石墨烯叠层的石墨烯之间的插层物质，并且是以XRD图案表示的扩展石墨，其分别在2θ的7-12°和18-24°范围内显示峰值，其中在25-27°范围内的峰 具有比18-24°范围更小的高度，7-12°范围内的峰的半宽度为4度或更小。 制造碳质材料的方法包括将片状石墨或片状预膨胀石墨的至少一部分浸入电解质水溶液中以使石墨进行电化学处理。 用于生产剥离石墨的方法包括对碳质材料施加剥离力以获得剥离石墨的步骤。 通过该制造方法得到剥离石墨。