-
公开(公告)号：US20120214808A1
公开(公告)日：2012-08-23
申请号：US13399517
申请日：2012-02-17
Applicant: Jason Bloxham , Matthew Colin Thor Fyfe , James Horswill , Revathy Perpetua Jeevaratnam , John Keily , Martin James Procter , Karen Lesley Schofield , Salam Shaaban , Simon Andrew Swain , Philippe Wong-Kai-In
Inventor： Jason Bloxham , Matthew Colin Thor Fyfe , James Horswill , Revathy Perpetua Jeevaratnam , John Keily , Martin James Procter , Karen Lesley Schofield , Salam Shaaban , Simon Andrew Swain , Philippe Wong-Kai-In
IPC: A61K31/5377 , C07D277/38 , A61K31/381 , C07D333/50 , C07D333/36 , A61K31/17 , C07C275/42 , A61K31/4164 , C07D233/56 , A61K31/428 , C07D277/82 , A61K31/44 , C07D213/72 , A61K31/5375 , C07D295/12 , A61K31/505 , C07D239/02 , C07D413/04 , A61P3/04 , A61P25/18 , A61P25/24 , A61P3/00 , A61P25/08 , A61P25/00 , A61K31/426
CPC classification number: A61K31/381 , A61K31/341 , A61K31/404 , A61K31/426 , A61K31/428 , A61K31/44 , A61K31/455
Abstract: A method of treating a condition associated with the CB-1 receptor, in particular obesity, by administering an effective amount of an aryl urea CB-1 receptor modulating compound to a subject in need of such treatment.
Abstract translation: 通过向需要这种治疗的受试者施用有效量的芳基脲CB-1受体调节化合物来治疗与CB-1受体相关的病症，特别是肥胖症的方法。
-
公开(公告)号：US20110178054A1
公开(公告)日：2011-07-21
申请号：US13003573
申请日：2009-07-10
Applicant: Lisa Sarah Bertram , Matthew Colin Thor Fyfe , William Gattrell , Revathy P. Jeevaratnam , John Keily , Martin James Procter
Inventor： Lisa Sarah Bertram , Matthew Colin Thor Fyfe , William Gattrell , Revathy P. Jeevaratnam , John Keily , Martin James Procter
IPC: A61K31/454 , C07D413/04 , C07D413/14 , A61K31/5377 , A61P3/04 , A61P3/10 , A61P3/00 , A61P3/06 , A61P9/12
CPC classification number: C07D413/04 , C07D413/14
Abstract: Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR (GPR119) agonists and are useful as for the treatment of diabetes and obesity.
Abstract translation: 式（I）化合物或其药学上可接受的盐是GPCR（GPR119）激动剂，可用于治疗糖尿病和肥胖症。
-
公开(公告)号：US07582632B2
公开(公告)日：2009-09-01
申请号：US11735685
申请日：2007-04-16
Applicant: Matthew Colin Thor Fyfe , Lisa Sarah Gardner , Maseo Nawano , Martin James Procter , Chrystelle Marie Rasamison , Karen Lesley Schofield , Vilasben Kanji Shah , Kosuke Yasuda
Inventor： Matthew Colin Thor Fyfe , Lisa Sarah Gardner , Maseo Nawano , Martin James Procter , Chrystelle Marie Rasamison , Karen Lesley Schofield , Vilasben Kanji Shah , Kosuke Yasuda
IPC: A61K31/4433 , A61P3/00 , C07D405/12 , C07D413/12 , C07D417/12
CPC classification number: C07D231/12 , C07D211/34 , C07D213/55 , C07D233/56 , C07D249/08 , C07D277/30 , C07D277/40 , C07D277/46 , C07D307/54 , C07D309/04 , C07D309/08 , C07D333/24 , C07D333/28 , C07D335/02 , C07D405/10 , C07D405/12 , C07D407/12 , C07D409/10 , C07D413/12 , C07D417/12 , C07D417/14 , C07D491/08
Abstract: Compounds of Formula (I): or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
Abstract translation: 式（I）化合物或其药学上可接受的盐可用于预防和治疗高血糖症和糖尿病。
-
公开(公告)号：US07214681B2
公开(公告)日：2007-05-08
申请号：US10776584
申请日：2004-02-10
Applicant: Matthew Colin Thor Fyfe , Lisa Sarah Gardner , Maseo Nawano , Martin James Procter , Chrystelle Marie Rasamison , Karen Lesley Schofield , Vilasben Kanji Shah , Kosuke Yasuda
Inventor： Matthew Colin Thor Fyfe , Lisa Sarah Gardner , Maseo Nawano , Martin James Procter , Chrystelle Marie Rasamison , Karen Lesley Schofield , Vilasben Kanji Shah , Kosuke Yasuda
IPC: A61K31/502 , C07D43/02
CPC classification number: C07D231/12 , C07D211/34 , C07D213/55 , C07D233/56 , C07D249/08 , C07D277/30 , C07D277/40 , C07D277/46 , C07D307/54 , C07D309/04 , C07D309/08 , C07D333/24 , C07D333/28 , C07D335/02 , C07D405/10 , C07D405/12 , C07D407/12 , C07D409/10 , C07D413/12 , C07D417/12 , C07D417/14 , C07D491/08
Abstract: Compounds of Formula (I): or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
Abstract translation: 式（I）化合物或其药学上可接受的盐可用于预防和治疗高血糖症和糖尿病。
-
公开(公告)号：US07074933B2
公开(公告)日：2006-07-11
申请号：US10775464
申请日：2004-02-10
Applicant: Daniel Y. Du , Martin James Procter , Matthew Colin Thor Fyfe , Vilasben Kanji Shah , Geoffrey Martyn Williams , Karen Lesley Schofield
Inventor： Daniel Y. Du , Martin James Procter , Matthew Colin Thor Fyfe , Vilasben Kanji Shah , Geoffrey Martyn Williams , Karen Lesley Schofield
IPC: C07D215/38 , C07D311/02 , A61K31/47
CPC classification number: C07D405/12 , C07D215/38 , C07D311/14 , C07D407/12
Abstract: The invention is directed to a new class of quinolin-zene and z-exc chromen compounds that have been derivatized at the 6-position with a urea or this urea moet, and to then use as androgen antagonists.
Abstract translation: 本发明涉及一种新的喹啉和z-激音色素化合物，它们已经在尿素或这种尿素环上在6位被衍生化，然后用作雄激素拮抗剂。
-
Patent Agency Ranking
公开(公告)号：US07064207B2
公开(公告)日：2006-06-20
申请号：US10758582
申请日：2004-01-15
Applicant: Daniel Y. Du , Matthew Colin Thor Fyfe , Martin James Procter , Karen Lesley Schofield , Vilasben Kanji Shah , Geoffrey Martyn Williams
Inventor： Daniel Y. Du , Matthew Colin Thor Fyfe , Martin James Procter , Karen Lesley Schofield , Vilasben Kanji Shah , Geoffrey Martyn Williams
IPC: C07D215/16 , C07D311/04
CPC classification number: C07D215/36 , C07D215/227 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/10
Abstract: The present invention is directed to a new class of 6-sulfonamido-quinolin-2-one and 6-sulfonamido-2-oxo-chromene derivatives to their use as androgen antagonists, and to relieve conditions associated with inappropriate activation of the androgen receptor.
Abstract translation: 本发明涉及一类新的6-亚磺酰氨基 - 喹啉-2-酮和6-亚磺酰氨基-2-氧代 - 色烯衍生物，用于雄激素拮抗剂，并减轻与雄激素受体不适当激活相关的病症。
-
公开(公告)号：US20090221644A1
公开(公告)日：2009-09-03
申请号：US11922830
申请日：2006-06-29
Applicant: Stuart Edward Bradley , Matthew Colin Thor Fyfe , Lisa Sarah Bertram , William Gattrell , Martin James Procter , Chrystelle Marie Rasamison , Colin Peter Sambrook-Smith , Vilasben Kanji Shah , David French Stonehouse , Simon Andrew Swain , Gerard Hugh Thomas
Inventor： Stuart Edward Bradley , Matthew Colin Thor Fyfe , Lisa Sarah Bertram , William Gattrell , Martin James Procter , Chrystelle Marie Rasamison , Colin Peter Sambrook-Smith , Vilasben Kanji Shah , David French Stonehouse , Simon Andrew Swain , Gerard Hugh Thomas
IPC: A61K31/443 , C07D405/12 , A61P3/10
CPC classification number: C07D471/04 , C07D405/06 , C07D405/12 , C07D413/14 , C07D417/14 , C07D495/04
Abstract: Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
Abstract translation: 式（I）化合物或其药学上可接受的盐是GPCR激动剂，可用于治疗肥胖症和糖尿病。
-
公开(公告)号：US20090005391A1
公开(公告)日：2009-01-01
申请号：US12091947
申请日：2006-11-03
Applicant: Matthew Colin Thor Fyfe , Martin James Procter
Inventor： Matthew Colin Thor Fyfe , Martin James Procter
IPC: A61K31/4433 , A61P3/00 , A61P3/10 , C07D405/12 , C07D413/12 , C07D417/12 , A61K31/497 , A61K31/506 , A61K31/4155 , A61K31/501 , A61K31/427 , A61K31/422
CPC classification number: C07D405/12 , C07D413/12 , C07D417/12
Abstract: Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
Abstract translation: 式（I）化合物或其药学上可接受的盐可用于预防和治疗高血糖症和糖尿病。
-
公开(公告)号：US07009052B2
公开(公告)日：2006-03-07
申请号：US10801910
申请日：2004-03-16
Applicant: Daniel Y. Du , Matthew Colin Thor Fyfe , Martin James Procter , Karen Lesley Schofield , Vilasben Kanji Shah , Geoffrey Martyn Williams
Inventor： Daniel Y. Du , Matthew Colin Thor Fyfe , Martin James Procter , Karen Lesley Schofield , Vilasben Kanji Shah , Geoffrey Martyn Williams
IPC: C07D215/16 , C07D311/74 , A61K31/47
CPC classification number: C07D215/38 , C07D215/36 , C07D215/40 , C07D311/14 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: The present invention is directed to a new class of 6-sulfonamide quinoline and chromene derivative and to their use as androgen antagonists.
Abstract translation: 本发明涉及一类新的6-磺酰胺喹啉和色烯衍生物及其作为雄激素拮抗剂的用途。
-
公开(公告)号：US08207147B2
公开(公告)日：2012-06-26
申请号：US10584025
申请日：2004-12-23
Applicant: Matthew Colin Thor Fyfe , Lisa Sarah Gardner , John King-Underwood , Martin James Procter , Chrystelle Marie Rasamison , Karen Lesley Schofield , Gerard Hugh Thomas
Inventor： Matthew Colin Thor Fyfe , Lisa Sarah Gardner , John King-Underwood , Martin James Procter , Chrystelle Marie Rasamison , Karen Lesley Schofield , Gerard Hugh Thomas
IPC: A61K31/66 , A61K31/497 , A61K31/4523 , C07D401/14 , C07F9/02 , C07D211/00 , C07D413/14
CPC classification number: C07D413/14 , C07D401/14 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/14
Abstract: Compounds of Formula (I), R1-A-V—B—R2; or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful as regulators of satiety, e.g. for the treatment of obesity, and for the treatment of diabetes.
Abstract translation: 式（I）的化合物，R1-A-V-B-R2; 或其药学上可接受的盐是GPR116的激动剂，并且可用作饱腹感的调节剂，例如， 用于治疗肥胖症和治疗糖尿病。
-
-
-
-
-
-
-
-
-
Search Results
38
records
(took 0.027 seconds)
