公开(公告)号：USD293374S

公开(公告)日：1987-12-22

申请号：US672928

申请日：1984-11-19

申请人： Max Herzberg ,  Falk Fish

设计人： Max Herzberg ,  Falk Fish

公开(公告)号：US4549011A

公开(公告)日：1985-10-22

申请号：US533770

申请日：1983-09-19

申请人： Max Herzberg ,  Falk Fish

发明人： Max Herzberg ,  Falk Fish

IPC分类号： G01N33/547 ,  A61F13/00 ,  A61K39/00 ,  B01D15/08 ,  B01D71/10 ,  B01J20/28 ,  C08L1/02 ,  C12Q1/00 ,  G01N33/543 ,  G01N33/558

CPC分类号： B01D71/10 ,  B01D15/3804 ,  B01D61/00 ,  B01D67/0093 ,  B01J20/28033 ,  G01N33/54353 ,  G01N33/558 ,  B01D2311/2626

摘要： A sheet for separating and retaining biological molecules. The sheet is activated with a compound for covalently binding a ligand to said sheet, and then coated with ligands having an affinity for the substance of interest. A method of using the sheet for isolating and separating substances of interest and methods for forming the sheet.

摘要翻译： 用于分离和保留生物分子的片材。 该片用化合物活化，用于将配体共价结合到所述片材上，然后用对目标物质具有亲和性的配体包被。 用于分离和分离感兴趣物质的片材的方法和用于形成片材的方法。

公开(公告)号：US5126276A

公开(公告)日：1992-06-30

申请号：US113395

申请日：1987-10-19

申请人： Falk Fish ,  Max Herzberg ,  Menachem Ritterband

发明人： Falk Fish ,  Max Herzberg ,  Menachem Ritterband

IPC分类号： A61K39/00 ,  B01L3/00 ,  G01N33/543

CPC分类号： B01L3/5085 ,  G01N33/54366 ,  Y10S435/973 ,  Y10S435/975 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/809 ,  Y10S436/81 ,  Y10S436/82

摘要： A solid phase immuno-assay system for assaying at least one analyte, in the form of a solid support having a plurality of receptors bound thereto. At least two of the receptors conjugate with the same analyte.A reaction container comprising a plurality of longitudinally arranged individual compartments, and a longitudinally extending single compartment.A card for assaying a plurality of samples for the same analyte, having a plurality of receptors for the analyte at different locations on the card.A method of performing an assay for the same analyte in more than one sample, by providing a receptor for the analyte at more than a single location on a solid substrate; exposing each of the receptors to different samples; and developing each of the receptor locations to indicate the presence of the analyte in each of the samples.

摘要翻译： 一种用于测定至少一种分析物的固相免疫测定系统，其具有结合有多个受体的固体支持物的形式。 至少两个受体与相同的分析物共轭。 反应容器，其包括多个纵向排列的单个隔室，以及纵向延伸的单个隔室。 用于分析相同分析物的多个样品的卡，其具有用于在卡上不同位置处的分析物的多个受体。 通过在固体基质上超过单个位置提供分析物的受体来对多于一个样品进行相同分析物的测定的方法; 将每个受体暴露于不同的样品; 并开发每个受体位置以指示每个样品中分析物的存在。

公开(公告)号：US20060110283A1

公开(公告)日：2006-05-25

申请号：US10516053

申请日：2003-11-12

申请人： Falk Fish

发明人： Falk Fish

IPC分类号： G01N21/64

CPC分类号： G01N21/272 ,  G01N21/03 ,  G01N21/82 ,  G01N21/8483 ,  G01N33/4905 ,  G01N33/86 ,  G01N2021/0321 ,  G01N2021/0328 ,  G01N2021/0346 ,  G01N2021/825 ,  G01N2201/0221 ,  G01N2201/0624

摘要： A device, system and method for photometric detection of coagulation in whole blood. The present invention is easy to implement and operate. Furthermore, the present invention has the advantage of being considered to fulfill the desired standard of using photometry for measuring blood coagulation. Also, a photometric coagulation test device for whole blood specimens according to the present invention provides medical accuracy to the home user and, at the same time, is simple to construct. The present invention is also useful for detecting and determining blood agglutination, for example as the results of a serological reaction with an antibody.

摘要翻译： 全血凝结光度检测装置，系统及方法。 本发明易于实现和操作。 此外，本发明的优点在于被认为满足使用光度法测量血液凝固的期望标准。 此外，根据本发明的用于全血样本的光度凝固测试装置向家庭用户提供医学准确性，并且同时构造简单。 本发明也可用于检测和测定血液凝集，例如作为与抗体血清学反应的结果。

公开(公告)号：US07591978B2

公开(公告)日：2009-09-22

申请号：US11502192

申请日：2006-08-10

申请人： Oren Shraga Dwir ,  Tomer Keren ,  Falk Fish

发明人： Oren Shraga Dwir ,  Tomer Keren ,  Falk Fish

IPC分类号： G01N21/00

CPC分类号： C12Q1/34 ,  C12Q2334/50 ,  C12Q2334/52 ,  G01N2333/195 ,  G01N2333/30 ,  G01N2333/36 ,  G01N2800/36

摘要： A solid-phase test device and a method for the detection of sialidase activity in a fluid sample. The test device includes a solid support provided with a pre-deposited dry form of a sialidase detecting composition. The sialidase detecting composition includes a sialidase substrate and a color-developing reagent. When the sialidase substrate is exposed to sialidase it yields an intermediate compound which reacts with the color-developing reagent to form a detectable color change.

摘要翻译： 固相试验装置和用于检测流体样品中唾液酸酶活性的方法。 测试装置包括具有预沉积干燥形式的唾液酸酶检测组合物的固体支持物。 唾液酸酶检测组合物包括唾液酸酶底物和显色剂。 当唾液酸酶底物暴露于唾液酸酶时，产生与显色剂反应形成可检测颜色变化的中间体化合物。

公开(公告)号：US20050109951A1

公开(公告)日：2005-05-26

申请号：US10500186

申请日：2002-12-26

申请人： Falk Fish ,  Zvi Greenberg ,  Ouriel Faktor

发明人： Falk Fish ,  Zvi Greenberg ,  Ouriel Faktor

IPC分类号： G01N21/64 ,  G01N21/75 ,  G01N21/77 ,  G01N21/86

CPC分类号： G01N21/645 ,  G01N21/64 ,  G01N21/8483 ,  G01N33/549 ,  G01N2021/6439 ,  G01N2021/757 ,  G01N2021/7759 ,  G01N2021/7763 ,  G01N2021/7786 ,  G01N2201/0221 ,  G01N2201/0222 ,  G01N2201/0245 ,  G01N2201/062 ,  G01N2201/0628

摘要： A device, system and method for portable fluorescence detection. The portable device of the present invention features a low power light, in which a wavelength range is defined as at least one wavelength of light. The light source is preferably highly energy efficient, such that a majority of the electrical power which is consumed is then converted into transmitted light. The emitted light from the excited fluorophore is then preferably detected with any low cost and low power photodetector. Although optionally a highly sensitive optical detector may be used, preferably fluorescence is detected with any light sensing device, such as a regular photodiode or a CCD (charge-coupled device) sensor for example.

摘要翻译： 用于便携式荧光检测的装置，系统和方法。 本发明的便携式装置具有低功率光，其中波长范围被定义为至少一个波长的光。 光源优选地是高能量的，使得消耗的大部分电功率然后被转换成透射光。 然后优选用任何低成本和低功率光电检测器检测来自激发的荧光团的发射光。 尽管可选地使用高灵敏度的光学检测器，但是优选地，例如使用诸如常规光电二极管或CCD（电荷耦合器件）传感器的任何光感测装置来检测荧光。

公开(公告)号：US20080241953A1

公开(公告)日：2008-10-02

申请号：US12065780

申请日：2006-09-06

申请人： Falk Fish

发明人： Falk Fish

IPC分类号： G01N21/78 ,  B01J19/00 ,  B41F1/00

CPC分类号： B01L3/5023 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0636 ,  B01L2300/0681 ,  B01L2300/0825 ,  B01L2300/126 ,  B01L2300/165 ,  D21H25/005

摘要： A method of patterning a bibulous substrate is disclosed. The method comprises contacting the bibulous substrate with a first surface being coated by a barrier compound, using a second surface having a predetermined pattern engraved thereon, and applying heat and pressure onto the first surface such as to pattern the bibulous substrate in a predetermined pattern.

摘要翻译： 公开了一种图案化吸水性衬底的方法。 该方法包括使吸水性衬底与被阻挡化合物涂覆的第一表面接触，使用刻在其上的预定图案的第二表面，并将热和压力施加到第一表面上，以便以预定图案对吸水衬底进行图案化。

公开(公告)号：US07060453B1

公开(公告)日：2006-06-13

申请号：US09763415

申请日：1999-08-19

申请人： Falk Fish

发明人： Falk Fish

IPC分类号： C12Q1/54 ,  C12Q1/00 ,  A01N1/02 ,  A61K39/00 ,  A61K45/00

CPC分类号： G01N33/66 ,  G01N33/50 ,  G01N33/721 ,  Y10T436/25375

摘要： A method is provided for determining the level of an analyte in the blood of an individual based on determination of the level of the same analyte in non-blood sample (e.g. urine, saliva and hair) obtained from the individual. The non-blood sample contains red blood cells and the volume of the blood in the sample together with the amount of the analyte in the sample are the basis for calculating the level of the analyte in the individual's blood. Kits for carrying out the above method are also provided.

摘要翻译： 提供了一种用于基于从个体获得的非血液样品（例如尿液，唾液和头发）中相同分析物的水平的测定来确定个体血液中分析物的水平的方法。 非血液样品含有红细胞，样品中的血液体积和样品中的分析物的量是计算个体血液中分析物水平的基础。 还提供了用于执行上述方法的套件。

公开(公告)号：US20060105402A1

公开(公告)日：2006-05-18

申请号：US11272971

申请日：2005-11-15

申请人： Gennady Rott ,  Fred Samuels ,  Falk Fish ,  Ariela Ben-Zvi

发明人： Gennady Rott ,  Fred Samuels ,  Falk Fish ,  Ariela Ben-Zvi

IPC分类号： G01N33/567 ,  C12Q1/56 ,  C12M1/34

CPC分类号： G01N33/543 ,  G01N33/5302 ,  G01N33/54313 ,  G01N33/80

摘要： A method for the detection and/or visualization of particle agglutination in a particle suspension is provided, comprising placing a volume of the particle suspension and a volume of a solution or suspension containing an agglutinating agent at substantially the same selected location on a surface of a filter constructed so as to permit passage of individual unagglutinated particles in a direction perpendicular to the surface. A wash solution at optionally placed at substantially the same location as that of said agglutinating agent, and the surface is observed for the presence of particles. There is also provided a method for detection of agglutination reactions, such as used in blood grouping, reverse grouping and cross-matching. A device and a kit based on the invention is also claimed, which facilitates blood grouping, reverse grouping and matching in non-laboratory environment without the need for laboratory instruments.

摘要翻译： 提供了用于检测和/或可视化颗粒悬浮液中的颗粒凝集的方法，包括将体积的颗粒悬浮液和一定体积的含有凝集剂的溶液或悬浮液放置在基本上相同的选定位置的 过滤器被构造成允许单个未凝集的颗粒在垂直于表面的方向上通过。 任选地在与所述凝集剂的位置基本上相同的位置处的洗涤溶液，并观察表面存在颗粒。 还提供了用于血液分组，反向分组和交叉匹配中使用的凝集反应检测方法。 还要求保护基于本发明的装置和试剂盒，其不需要实验室仪器便于非实验室环境中的血液分组，反向分组和匹配。

公开(公告)号：US20230015833A1

公开(公告)日：2023-01-19

申请号：US17857096

申请日：2022-07-04

申请人： Natalia Shtraizent ,  Henry Grage ,  Falk Fish

发明人： Natalia Shtraizent ,  Henry Grage ,  Falk Fish

IPC分类号： G01N33/76 ,  G01N33/74 ,  G16H70/60 ,  G16H10/60

摘要： A method and system for measuring hormone levels in human samples. Either actual levels can be measured, or hormone related parameters can be measured with computation extrapolating the parameters to the actual hormone level. A patient hormone level can be compared against a population database based on age, gender and other factors to determine a score for a particular hormone. A dosage of the hormone being given a patient can be automatically adjusted based on the score with optional approval of the adjustment made by a health professional. This is particularly useful in hormone replacement therapy and in-vitro fertilization.