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    Sorbents for the oxidation and removal of mercury
    4.
    发明申请
    Sorbents for the oxidation and removal of mercury 有权

    公开(公告)号：US20060048646A1

    公开(公告)日：2006-03-09

    申请号：US11209163

    申请日：2005-08-22

    Applicant: Edwin Olson ,  Michael Holmes ,  John Pavlish

    Inventor： Edwin Olson ,  Michael Holmes ,  John Pavlish

    IPC: B01D53/02

    CPC classification number: B01D53/64 ,  B01D53/10 ,  B01D2253/102 ,  B01D2257/602 ,  B01J20/20 ,  B01J20/22 ,  Y10S95/901

    Abstract: A promoted activated carbon sorbent is described that is highly effective for the removal of mercury from flue gas streams. The sorbent comprises a new modified carbon form containing reactive forms of halogen and halides. Optional components may be added to increase reactivity and mercury capacity. These may be added directly with the sorbent, or to the flue gas to enhance sorbent performance and/or mercury capture. Mercury removal efficiencies obtained exceed conventional methods. The sorbent can be regenerated and reused. Sorbent treatment and preparation methods are also described. New methods for in-flight preparation, introduction, and control of the active sorbent into the mercury contaminated gas stream are described.

    Method of and apparatus for detecting misfire
    5.
    发明授权
    Method of and apparatus for detecting misfire 失效
    用于检测MISFIRE的方法和装置

    公开(公告)号：US5237504A

    公开(公告)日：1993-08-17

    申请号：US655568

    申请日：1991-02-13

    Applicant: Michael Holmes ,  Benjamin J. Bradshaw

    Inventor： Michael Holmes ,  Benjamin J. Bradshaw

    IPC: F02D45/00 ,  F02P17/12 ,  G01M15/11

    CPC classification number: G01M15/11

    Abstract: In order to detect misfire in an internal combustion engine, engine speed is determined by measuring the time of passage of a crankshaft disc from a first position to a second position during every revolution. A detection circuit takes the reciprocal of the measured times of passage to form a series of engine speeds and forms the difference between consecutive engine speeds. These differences are compared with a threshold to signal a misfire when the threshold is exceeded.

    METHOD AND APPARATUS FOR MONITORING ANESTHESIA DRUG DOSAGES, CONCENTRATIONS, AND EFFECTS USING N-DIMENSIONAL REPRESENTATIONS OF CRITICAL FUNCTIONS
    8.
    发明申请
    METHOD AND APPARATUS FOR MONITORING ANESTHESIA DRUG DOSAGES, CONCENTRATIONS, AND EFFECTS USING N-DIMENSIONAL REPRESENTATIONS OF CRITICAL FUNCTIONS 审中-公开
    用于监测麻醉药物剂量，浓度和效果的方法和装置，使用关键功能的三维表示

    公开(公告)号：US20080033661A1

    公开(公告)日：2008-02-07

    申请号：US11843524

    申请日：2007-08-22

    Applicant: Noah Syroid ,  Dwayne Westenskow ,  Julio Bermudez ,  James Agutter ,  David Strayer ,  Robert Albert ,  Michael Holmes ,  Frank Drews ,  Haunke Prenzel

    Inventor： Noah Syroid ,  Dwayne Westenskow ,  Julio Bermudez ,  James Agutter ,  David Strayer ,  Robert Albert ,  Michael Holmes ,  Frank Drews ,  Haunke Prenzel

    IPC: G06F19/00

    CPC classification number: G09B23/28 ,  A61B5/00 ,  A61M5/142 ,  A61M16/021 ,  A61M2202/048 ,  A61M2205/3576 ,  A61M2205/6072 ,  G06F19/3456 ,  G16H50/50

    Abstract: A method, system and apparatus for the monitoring, diagnosis and evaluation of the state of a dynamic system is disclosed. This method and system provides the processing means for receiving sensed and/or simulated data, converting such data into a displayable object format and displaying such objects in a manner such that the interrelationships between the respective variables can be correlated and identified by a user. This invention provides for the rapid cognitive grasp of the overall state of a critical function with respect to a dynamic system. The system provides for displayed objects, which change in real-time to show the changes of the functions of the system. It is a highly flexible system which works with a wide variety of applications, including biological systems, environmental systems, engineering systems, economic systems, mechanical systems, chemical systems and the like. In particular, this invention is directed to the processing and display of drug data for the use of doctors in the process of monitoring or administering drugs to patients.

    Abstract translation: 公开了一种用于动态系统状态的监视，诊断和评估的方法，系统和装置。 该方法和系统提供了用于接收感测和/或模拟数据的处理装置，将这些数据转换成可显示对象格式，并以这样一种方式显示这些对象，使得各个变量之间的相互关系可以由用户相关和识别。 本发明提供了关于动态系统的关键功能的总体状态的快速认知掌握。 系统提供显示对象，实时更改以显示系统功能的更改。 它是一个高度灵活的系统，适用于各种应用，包括生物系统，环境系统，工程系统，经济系统，机械系统，化学系统等。 特别地，本发明涉及在向患者监测或给予药物的过程中使用医生的药物数据的处理和显示。

    Methods and compositions for targeted cleavage and recombination
    10.
    发明申请
    Methods and compositions for targeted cleavage and recombination 有权
    用于靶向切割和重组的方法和组合物

    公开(公告)号：US20050064474A1

    公开(公告)日：2005-03-24

    申请号：US10912932

    申请日：2004-08-06

    Applicant: Fyodor Urnov ,  Michael Holmes ,  Jeffrey Miller ,  Carl Pabo

    Inventor： Fyodor Urnov ,  Michael Holmes ,  Jeffrey Miller ,  Carl Pabo

    IPC: C07K14/435 ,  C07K14/47 ,  C07K14/715 ,  C12N9/14 ,  C12N9/22 ,  C12N15/62 ,  C12P19/34 ,  C12Q1/68

    CPC classification number: A61K35/12 ,  C07K14/43595 ,  C07K14/4717 ,  C07K14/715 ,  C07K2319/00 ,  C07K2319/09 ,  C07K2319/81 ,  C12N9/14 ,  C12N9/22 ,  C12N15/62 ,  C12N15/85 ,  C12N2800/80

    Abstract: Disclosed herein are methods and compositions for targeted cleavage of a genomic sequence, targeted alteration of a genomic sequence, and targeted recombination between a genomic region and an exogenous polynucleotide homologous to the genomic region. The compositions include fusion proteins comprising a cleavage domain (or cleavage half-domain) and an engineered zinc finger domain and polynucleotides encoding same. Methods for targeted cleavage include introduction of such fusion proteins, or polynucleotides encoding same, into a cell. Methods for targeted recombination additionally include introduction of an exogenous polynucleotide homologous to a genomic region into cells comprising the disclosed fusion proteins.

    Abstract translation: 本文公开了用于基因组序列的靶向切割，基因组序列的靶向改变以及基因组区域和与该基因组区域同源的外源多核苷酸之间的靶向重组的方法和组合物。 组合物包括包含切割结构域（或切割半结构域）和工程化锌指结构域的融合蛋白和编码它们的多核苷酸。 用于靶向切割的方法包括将这种融合蛋白或其编码的多核苷酸引入细胞。 用于靶向重组的方法另外包括将与基因组区域同源的外源多核苷酸引入包含所公开的融合蛋白的细胞中。

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