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公开(公告)号:US20100267574A1
公开(公告)日:2010-10-21
申请号:US12445596
申请日:2007-10-19
申请人: Ming You , Yan Lu , Ramaswamy Govindan , Mark A. Watson
发明人: Ming You , Yan Lu , Ramaswamy Govindan , Mark A. Watson
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/118
摘要: The present invention provides a plurality of biomarkers for predicting survival of a subject with a lung cancer. More specifically, the present invention relates to methods of predicting survival of a subject with a lung cancer, a kit for predicting survival of a subject with a lung cancer, and an array for predicting survival of a subject with lung cancer.
摘要翻译: 本发明提供了用于预测患有肺癌的受试者的存活的多种生物标志物。 更具体地,本发明涉及预测患有肺癌的受试者的存活的方法,用于预测患有肺癌的受试者的存活的试剂盒以及用于预测患有肺癌的受试者的存活的阵列。
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公开(公告)号:US08202968B2
公开(公告)日:2012-06-19
申请号:US12445596
申请日:2007-10-19
申请人: Ming You , Yan Lu , Ramaswamy Govindan , Mark A. Watson
发明人: Ming You , Yan Lu , Ramaswamy Govindan , Mark A. Watson
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/118
摘要: The present invention provides a plurality of biomarkers for predicting survival of a subject with a lung cancer. More specifically, the present invention relates to methods of predicting survival of a subject with a lung cancer, a kit for predicting survival of a subject with a lung cancer, and an array for predicting survival of a subject with lung cancer.
摘要翻译: 本发明提供了用于预测患有肺癌的受试者的存活的多种生物标志物。 更具体地,本发明涉及预测患有肺癌的受试者的存活的方法,用于预测患有肺癌的受试者的存活的试剂盒以及用于预测患有肺癌的受试者的存活的阵列。
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公开(公告)号:US07403281B2
公开(公告)日:2008-07-22
申请号:US10859372
申请日:2004-06-01
申请人: Keith T. Carron , Mark A. Watson , Shane A. Buller
发明人: Keith T. Carron , Mark A. Watson , Shane A. Buller
IPC分类号: G01J3/44
CPC分类号: G01J3/02 , G01J3/0272 , G01J3/0291 , G01J3/44 , G01J2003/4424 , G01N21/65 , G01N2201/0221 , G01N2201/0612 , G01N2201/0813
摘要: A system, method and apparatus for taking a Raman spectrum of a sample is disclosed. In one embodiment, for example, an integrated Raman spectrometer is provided. In another embodiment, a portable Raman spectrometer is provided. In another embodiment, a Raman spectrometer is provided comprising a collimated beam tube for transmitting excitation radiation to an external optical system, such as a microscope, a telescope or a camera lens. In another embodiment, a method for correcting a Raman spectrum for background interference is provided. In yet another embodiment, a method for rejecting fluorescence in a Raman spectrometer is provided. A chemical reactor comprising a built-in Raman detector for monitoring a chemical reaction in a reaction chamber of the reactor is also provided.
摘要翻译: 公开了一种用于获取样品的拉曼光谱的系统,方法和装置。 在一个实施例中,例如,提供了一种集成的拉曼光谱仪。 在另一个实施例中,提供了便携式拉曼光谱仪。 在另一个实施例中,提供拉曼光谱仪,其包括用于将激发辐射传输到诸如显微镜,望远镜或相机透镜的外部光学系统的准直束管。 在另一实施例中,提供了用于校正背景干扰的拉曼光谱的方法。 在另一个实施方案中,提供了一种用于在拉曼光谱仪中排除荧光的方法。 还提供了一种包括用于监测反应器的反应室中的化学反应的内置拉曼检测器的化学反应器。
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公开(公告)号:US20070285889A1
公开(公告)日:2007-12-13
申请号:US11761701
申请日:2007-06-12
申请人: Mark A. Watson , Robert E. Watson
发明人: Mark A. Watson , Robert E. Watson
IPC分类号: H05K7/20
CPC分类号: H05K9/0015
摘要: An electrical box for mining apparatus and a mining apparatus are provided. The electrical box includes a housing having an explosion proof enclosure and a cooling duct. An electrical circuit is held in the enclosure. A fan is provided for forcing air through the cooling duct.
摘要翻译: 提供了采矿设备的电气箱和采矿设备。 电气箱包括具有防爆外壳和冷却导管的壳体。 电路保持在外壳中。 设置风扇用于迫使空气通过冷却管道。
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5.
公开(公告)号:US06566072B1
公开(公告)日:2003-05-20
申请号:US09162622
申请日:1998-09-29
申请人: Mark A. Watson , Timothy P. Fleming
发明人: Mark A. Watson , Timothy P. Fleming
IPC分类号: G01N3353
CPC分类号: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/4721 , C12Q1/6886 , C12Q2600/158 , G01N33/57415 , G01N2800/52
摘要: A purified and isolated DNA sequence and the encoded mammary-specific secreted protein, mammaglobin, are disclosed. Also disclosed are methods for detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin. Immunotherapy-based methods for treating a breast cancer patient with a mammaglobin-expressing tumor are also disclosed. The methods involve using mammaglobin antigens to induce a humoral and/or cell-mediated immune response against the tumor.
摘要翻译: 公开了纯化和分离的DNA序列和编码的乳腺特异性分泌蛋白,乳腺球蛋白。 还公开了基于乳腺癌细胞的乳腺球蛋白的过表达和分泌来检测乳腺癌的方法。 该方法检测和/或定量乳腺球蛋白或编码乳腺球蛋白的mRNA的存在。 还公开了用表达乳腺球蛋白的肿瘤治疗乳腺癌患者的基于免疫疗法的方法。 该方法涉及使用乳腺球蛋白抗原诱导针对肿瘤的体液和/或细胞介导的免疫应答。
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6.
公开(公告)号:US06377182B1
公开(公告)日:2002-04-23
申请号:US09692758
申请日:2000-10-19
申请人: Mark A. Devine , Mark A. Watson , Andrew J. Ivanecky , Lulzim Osmani , Kenneth L. Venzant , Samuel D. Lopez
发明人: Mark A. Devine , Mark A. Watson , Andrew J. Ivanecky , Lulzim Osmani , Kenneth L. Venzant , Samuel D. Lopez
IPC分类号: G08B1710
CPC分类号: G08B17/107 , G08B17/10 , G08B17/113
摘要: A smoke detector has a geometry that locates a sensor or sensors at or near a boundary layer of smoke movement thus facilitating smoke entry into the sensor and/or sensors. The sensors are mounted so as to protrude from the bottom of a cover instead of into the cover of the detector.
摘要翻译: 烟雾探测器具有将传感器定位在烟雾运动的边界层附近或附近的几何形状,从而便于烟进入传感器和/或传感器。 传感器安装成从盖的底部突出而不是检测器的盖。
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公开(公告)号:US20080024133A1
公开(公告)日:2008-01-31
申请号:US11563047
申请日:2006-11-24
申请人: John Thomas Vaughan , Mark A. Watson , Kenneth M. Bradshaw , Matthew T. Waks , Joshua J. Holwell
发明人: John Thomas Vaughan , Mark A. Watson , Kenneth M. Bradshaw , Matthew T. Waks , Joshua J. Holwell
CPC分类号: G01R33/34046 , G01R33/3453 , G01R33/3678
摘要: An magnetic resonance apparatus in embodiments of the invention may include one or more of the following features: (a) a coil having at least two sections, (b) the at least two sections having a resonant circuit, (c) the at least two sections being reactively coupled or decoupled, (d) the at least two sections being separable, (e) the coil having openings allowing a subject to see or hear and to be accessed through the coil, (f) a cushioned head restraint, and (g) a subject input/output device providing visual data to the subject, the input/output device being selected from the group consisting of mirrors, prisms, video monitors, LCD devices, and optical motion trackers.
摘要翻译: 在本发明的实施例中的磁共振装置可以包括以下特征中的一个或多个:(a)具有至少两个部分的线圈,(b)所述至少两个部分具有谐振电路,(c)所述至少两个部分 (d)所述至少两个部分是可分离的,(e)所述线圈具有允许受试者看到或听到并且通过线圈进入的开口,(f)缓冲的头枕,和 g)被摄体输入/输出装置,向对象提供视觉数据,输入/输出装置从由镜子,棱镜,视频监视器,LCD装置和光学运动跟踪器组成的组中选择。
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公开(公告)号:US06938506B2
公开(公告)日:2005-09-06
申请号:US10072020
申请日:2002-02-06
申请人: Kent D. Henry , Mark A. Watson , Shanen Onken-Shaw
发明人: Kent D. Henry , Mark A. Watson , Shanen Onken-Shaw
CPC分类号: G01D21/02 , G01D11/24 , G01N33/1886 , G01N33/1893
摘要: A sensor head apparatus is configured to include a plurality of sensor ports each configured to receive and electrically interconnect with a sensor head component. The sensor head is further configured to be connectable to a housing for a multi-parameter monitoring tool assembly, wherein electrical connections are provided between the electronics for the tool assembly and any sensor head component engaged in the sensor head. Each port in the sensor head is configured to receive and engage a sensor head component through application of a linear force on the component.
摘要翻译: 传感器头设备被配置为包括多个传感器端口,每个传感器端口被配置为接收并与传感器头部件电互连。 传感器头还被构造成可连接到用于多参数监测工具组件的壳体,其中在用于工具组件的电子装置和接合在传感器头部中的任何传感器头部件之间提供电连接。 传感器头中的每个端口构造成通过在部件上施加线性力来接收和接合传感器头部件。
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公开(公告)号:US5968754A
公开(公告)日:1999-10-19
申请号:US82343
申请日:1998-05-20
申请人: Mark A. Watson , Timothy P. Fleming
发明人: Mark A. Watson , Timothy P. Fleming
IPC分类号: C12N15/09 , A61K38/00 , C07H21/04 , C07K14/47 , C07K14/82 , C07K16/32 , C12P21/08 , C12Q1/68 , G01N33/574 , C07K16/00 , G01N33/53
CPC分类号: C07K14/47 , C12Q1/6886 , G01N33/57415 , A61K38/00 , C12Q2600/112
摘要: A purified and isolated DNA sequence and the encoded mammary-specific protein, mammaglobin, are disclosed. Also disclosed are methods for the detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin.
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公开(公告)号:US07007541B2
公开(公告)日:2006-03-07
申请号:US10072203
申请日:2002-02-06
申请人: Kent D. Henry , Neal W. Syverson , Ronny D. Harris , Zachary A. Gray , Mark A. Watson , Stanley B. Smith
发明人: Kent D. Henry , Neal W. Syverson , Ronny D. Harris , Zachary A. Gray , Mark A. Watson , Stanley B. Smith
IPC分类号: G01N33/00
CPC分类号: G01D21/02 , G01D3/022 , G01D11/24 , G01N33/1886 , G01N33/1893
摘要: A plurality of multi-parameter monitoring tool assemblies are connectable over a communications network and are further in communication with a central controller. Each of the tool assemblies is configured to interconnect with one or more sensor head components which may be employable in the monitoring of water quality. According to the system described herein, the central controller may periodically communicate with one or more of the tool assemblies connected in the communications network and extract, process, and display information as to the configuration and operation of one or more tool assemblies.
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