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公开(公告)号：US09304088B2
公开(公告)日：2016-04-05
申请号：US13400106
申请日：2012-02-19
申请人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
发明人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
CPC分类号： G01N21/80 , C12M41/26 , G01N21/3151 , G01N31/221 , G01N2201/0627 , G01N2201/1211
摘要： A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.
摘要翻译： 测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在所述测量区域的另一侧上接收所发射的光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。
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公开(公告)号：US20120214250A1
公开(公告)日：2012-08-23
申请号：US13400106
申请日：2012-02-19
申请人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
发明人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
IPC分类号： G01N21/59
CPC分类号： G01N21/80 , C12M41/26 , G01N21/3151 , G01N31/221 , G01N2201/0627 , G01N2201/1211
摘要： A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances ; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.
摘要翻译： 测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在测量区域的另一侧上接收发射光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。
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公开(公告)号：US09291572B2
公开(公告)日：2016-03-22
申请号：US13441630
申请日：2012-04-06
申请人： Mitsuhiro Oura , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
发明人： Mitsuhiro Oura , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
CPC分类号： G01N21/80 , C12M41/26 , G01N31/221 , G01N2021/3148 , G01N2021/3181 , G01N2201/0627
摘要： A pH measuring method includes: illuminating a medium solution, which includes: a first material; and a second material, with a plurality of light beams, which includes: a first light beam, a wavelength of which corresponds to a first absorption peak; a second light beam, a wavelength of which corresponds to a second absorption peak or a second convergence point; a third light beam, a wavelength of which corresponds to a third absorption peak or a third convergence point; and a fourth light beam, a wavelength of the fourth light beam at which an absorbance of at least one of the first and second materials is converged irrespective of a pH; receiving transmitted or reflected light beams of the first to fourth light beams; measuring absorbances at the wavelengths of the received light beams respectively; and calculating a pH of the medium solution based on the absorbances.
摘要翻译： pH测量方法包括：照射介质溶液，其包括：第一材料; 以及具有多个光束的第二材料，其包括：第一光束，其波长对应于第一吸收峰; 第二光束，其波长对应于第二吸收峰或第二会聚点; 第三光束，其波长对应于第三吸收峰或第三会聚点; 以及第四光束，所述第四光束的波长，其中所述第一和第二材料中的至少一个的吸光度在不同pH下会聚; 接收第一至第四光束的透射或反射光束; 分别测量接收光束波长处的吸光度; 并基于吸光度计算介质溶液的pH。
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公开(公告)号：US09783773B2
公开(公告)日：2017-10-10
申请号：US13432658
申请日：2012-03-28
申请人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda
发明人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda
摘要： A cell culture apparatus includes: an isolator in which a sterile space accommodating a cell incubator filled with a culture solution containing cells to be cultured is disposed; a sampling unit configured to sample the culture solution in the cell incubator; a delivery flow path through which an inside of the sterile space and an outside of the sterile space communicate with each other, the delivery flow path configured to limit a flow in the delivery flow path to a direction that is directed from the inside of the sterile space toward the outside of the sterile space; and a culture solution delivering section configured to deliver the sampled culture solution to the outside of the sterile space via the delivery flow path.
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公开(公告)号：US20120253692A1
公开(公告)日：2012-10-04
申请号：US13441630
申请日：2012-04-06
申请人： Mitsuhiro OURA , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
发明人： Mitsuhiro OURA , Hirotsugu Kubo , Sunao Takeda , Teruo Okano , Tatsuya Shimizu
CPC分类号： G01N21/80 , C12M41/26 , G01N31/221 , G01N2021/3148 , G01N2021/3181 , G01N2201/0627
摘要： A pH measuring method includes: illuminating a medium solution, which includes: a first material; and a second material, with a plurality of light beams, which includes: a first light beam, a wavelength of which corresponds to a first absorption peak; a second light beam, a wavelength of which corresponds to a second absorption peak or a second convergence point; a third light beam, a wavelength of which corresponds to a third absorption peak or a third convergence point; and a fourth light beam, a wavelength of the fourth light beam at which an absorbance of at least one of the first and second materials is converged irrespective of a pH; receiving transmitted or reflected light beams of the first to fourth light beams; measuring absorbances at the wavelengths of the received light beams respectively; and calculating a pH of the medium solution based on the absorbances.
摘要翻译： pH测量方法包括：照射介质溶液，其包括：第一材料; 以及具有多个光束的第二材料，其包括：第一光束，其波长对应于第一吸收峰; 第二光束，其波长对应于第二吸收峰或第二会聚点; 第三光束，其波长对应于第三吸收峰或第三会聚点; 以及第四光束，所述第四光束的波长，其中所述第一和第二材料中的至少一个的吸光度在不同pH下会聚; 接收第一至第四光束的透射或反射光束; 分别测量接收光束波长处的吸光度; 并基于吸光度计算介质溶液的pH。
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公开(公告)号：US20120214225A1
公开(公告)日：2012-08-23
申请号：US13400107
申请日：2012-02-19
申请人： Mitsuhiro OURA , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Katsuyoshi Suzuki , Sunao Takeda
发明人： Mitsuhiro OURA , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Katsuyoshi Suzuki , Sunao Takeda
IPC分类号： C12M3/00
摘要： A cell incubator includes: a culture cell accommodating section which accommodates cells to be cultured and a culture solution; and an RFID tag which is attached to the culture cell accommodating section and which is configured to transmit predetermined information to a communicating apparatus in response to reception of a signal that is wirelessly transmitted from the communicating apparatus.
摘要翻译： 细胞培养箱包括：容纳待培养细胞的培养细胞容纳部分和培养液; 以及RFID标签，其附接到所述培养单元容纳部，并且被配置为响应于从所述通信装置无线发送的信号的接收，向所述通信装置发送预定信息。
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公开(公告)号：US08882012B2
公开(公告)日：2014-11-11
申请号：US13217437
申请日：2011-08-25
申请人： Yuji Haraguchi , Tatsuya Shimizu , Teruo Okano , Takahiro Shioyama , Akane Suzuki , Sunao Takeda
发明人： Yuji Haraguchi , Tatsuya Shimizu , Teruo Okano , Takahiro Shioyama , Akane Suzuki , Sunao Takeda
CPC分类号： G01N1/286 , C12M41/02 , C12M45/02 , C12M47/04 , G01N2001/2866
摘要： A cell isolation apparatus includes: a chamber body which includes a chamber into which tissue is to be introduced; an isolation member which is moved in the chamber and which is to collide with the tissue to isolate a cell; and a controlling portion which controls an operation of the isolation member in the chamber body.
摘要翻译： 细胞分离装置包括：腔体，其包括要被导入组织的腔室; 隔离构件，其在腔室中移动并与组织碰撞以隔离细胞; 以及控制部分，其控制室主体中的隔离构件的操作。
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公开(公告)号：US08420028B2
公开(公告)日：2013-04-16
申请号：US13214774
申请日：2011-08-22
申请人： Akane Suzuki , Takahiro Shioyama , Sunao Takeda
发明人： Akane Suzuki , Takahiro Shioyama , Sunao Takeda
IPC分类号： A61B10/00
CPC分类号： G01N1/286 , G01N1/38 , G01N15/14 , G01N2001/085 , G01N2001/2866
摘要： A cell isolation apparatus includes: a cylinder member that is inserted into a container into which a reagent is to be introduced; a net which is stretched over the cylinder member; a tissue acquiring unit that is projected from the cylinder member; and a bottom lid portion that is configured by a bottomed pipe in which a first hole that communicates an interior with an exterior is formed, and that is fitted to a bottom portion of the cylinder member in a state where the net and the tissue acquiring unit are accommodated.
摘要翻译： 细胞隔离装置包括：插入到待引入试剂的容器中的圆筒构件; 在气缸构件上拉伸的网; 组织获取单元，其从所述圆筒构件突出; 以及底盖部，其由形成有与内部连通的第一孔的有底管构成，并且在所述网和所述组织获取单元的状态下嵌合到所述筒构件的底部， 被容纳。
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公开(公告)号：US07713197B2
公开(公告)日：2010-05-11
申请号：US11578910
申请日：2005-03-18
申请人： Makoto Nakai , Sunao Takeda , Akihiko Uchiyama , Kenji Yanashima , Akihiro Fujita , Itaru Yoshizawa
发明人： Makoto Nakai , Sunao Takeda , Akihiko Uchiyama , Kenji Yanashima , Akihiro Fujita , Itaru Yoshizawa
IPC分类号： A61B3/16 , G01L7/00 , G01L9/00 , G01L11/00 , G01L13/00 , G01L15/00 , G01L17/00 , G01L19/00 , G01L21/00 , G01L21/02
CPC分类号： G01L9/0022 , A61B3/16 , A61B5/0051 , G01L9/008
摘要： A tonometry device includes a contact device for contacting the object, means for vibrating the contact device and the object, means for applying a voltage to the vibration means, means for measuring a current flowing through the vibration means, and an information processing means. The information processing means determines two resonance points of the device and the measured object by measuring current through the system at a plurality of vibrational frequencies. The information processing means then determines the internal pressure of the object by determining that a first pressure is higher than a second pressure by determining that the first pressure has a lower measured current than the second pressure at frequencies outside of the range of frequencies between the resonance points, and that the first pressure has a higher measured current than the second pressure at frequencies within the range of frequencies between the resonance points.
摘要翻译： 测压装置包括用于接触物体的接触装置，用于振动接触装置和物体的装置，用于向振动装置施加电压的装置，用于测量流过振动装置的电流的装置，以及信息处理装置。 信息处理装置通过以多个振动频率测量通过系统的电流来确定装置和被测物体的两个共振点。 信息处理装置然后通过确定第一压力高于第二压力来确定对象的内部压力，通过确定第一压力具有比谐振频率范围之外的频率处的第二压力低的测量电流 并且第一压力在谐振点之间的频率范围内的频率处具有比第二压力更高的测量电流。
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公开(公告)号：US6008239A
公开(公告)日：1999-12-28
申请号：US135163
申请日：1998-08-17
申请人： Yasushi Kaneko , Sunao Takeda , Minoru Tokizawa , Hiromichi Eto , Kazuya Ishida , Kazunori Maebashi , Masaru Matsumoto , Takemitsu Asaoka , Susumu Sato
发明人： Yasushi Kaneko , Sunao Takeda , Minoru Tokizawa , Hiromichi Eto , Kazuya Ishida , Kazunori Maebashi , Masaru Matsumoto , Takemitsu Asaoka , Susumu Sato
IPC分类号： A01N43/653 , C07D249/08 , C07D521/00 , A61K31/505
CPC分类号： C07D231/12 , A01N43/653 , C07D233/56 , C07D249/08
摘要： Described is a triazole derivative represented by the formula (1): ##STR1## wherein R.sup.1 represents a lower alkyl group or an aralkyl group, R.sup.2 represents a hydrogen atom, a lower alkyl group, an aralkyl group or an acyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a trifluoromethyl group, n stands for an integer of 0 to 2 and m stands for an integer of 1 to 5, or salt thereof; and also a pharmaceutical comprising the derivative or salt thereof as an effective ingredient. The compound as described above has a high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.
摘要翻译： 描述了由式（1）表示的三唑衍生物：其中R1表示低级烷基或芳烷基，R2表示氢原子，低级烷基，芳烷基或酰基，X1和X2相同 或不同，各自独立地表示氢原子，卤素原子或三氟甲基，n表示0〜2的整数，m表示1〜5的整数，或其盐。 以及包含其衍生物或其盐作为有效成分的药物。 如上所述的化合物具有高的抗真菌活性，并且可用于预防和治疗哺乳动物真菌感染。
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