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公开(公告)号：US20240093221A1
公开(公告)日：2024-03-21
申请号：US18526363
申请日：2023-12-01
Applicant: Monsanto Technology LLC
Inventor： Edwards M. Allen , Bettina Darveaux , Stephen M. Duff , Mary Fernandes , Barry S. Goldman , Cara L. Griffith , Balasulojini Karunanandaa , Saritha V. Kuriakose , Paul J. Loida , Linda L. Lutfiyya , Robert J. Meister , Monnanda S. Rajani , Dhanalakshmi Ramachandra , Elena A. Rice , Daniel Ruzicka , Anagha M. Sant , Jon J. Schmuke , Rebecca L. Thompson , Srikanth Babu Venkatachalayya , Tyamagondlu V. Venkatesh , Huai Wang , Xiao Yang , Qin Zeng , Jianmin Zhao
CPC classification number: C12N15/8273 , A01H5/10 , C12N15/00 , C12N15/8213 , C12N15/8218 , C12N15/825
Abstract: This disclosure provides recombinant DNA constructs and transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency, and enhanced drought tolerance or water use efficiency. Transgenic plants may include field crops as well as plant propagules and progeny of such transgenic plants. Methods of making and using such transgenic plants are also provided. This disclosure also provides methods of producing seed from such transgenic plants, growing such seed, and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
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公开(公告)号：US10793869B2
公开(公告)日：2020-10-06
申请号：US15637859
申请日：2017-06-29
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Larry A Gilbertson , Sara E. Heisel , Shihshieh Huang , Elysia K. Krieger , Thomas M. Malvar
IPC: C12N15/82 , C12N15/113
Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
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公开(公告)号：US20130298281A1
公开(公告)日：2013-11-07
申请号：US13926621
申请日：2013-06-25
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Sergey Ivashuta , Molian Deng , Brian M. Hauge , Huai Wang
IPC: C12N15/82
CPC classification number: C12N15/8218 , C07K14/415 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12N15/8275 , Y02A40/146
Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US11414670B2
公开(公告)日：2022-08-16
申请号：US16847283
申请日：2020-04-13
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Jayanand Boddu , Charles R. Dietrich , Alexander Goldshmidt , Miya Howell , Kevin R. Kosola , Anil Neelam , Thomas L. Slewinski , Tyamagondlu V. Venkatesh , Huai Wang , Sivalinganna Manjunath , Linda Rymarquis
IPC: C12N15/82
Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through suppression, mutagenesis and/or editing of specific subtypes of GA20 or GA3 oxidase genes. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a GA oxidase gene are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
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公开(公告)号：US11008580B2
公开(公告)日：2021-05-18
申请号：US15958026
申请日：2018-04-20
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Sara E. Heisel , Sergey Ivashuta , Elysia K. Krieger , Jennifer Lutke , Robert J. Meister , Yuanji Zhang
IPC: C12N15/82
Abstract: This invention provides molecular constructs and methods for the temporally specific control of gene expression in plants or in plant pests or pathogens. More specifically, this invention provides plant miRNA genes having novel circadian expression patterns that are useful for designing recombinant DNA constructs for temporally specific expression of at least one gene. Also provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention.
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Patent Agency Ranking
公开(公告)号：US10724047B2
公开(公告)日：2020-07-28
申请号：US15679699
申请日：2017-08-17
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Jayanand Boddu , Charles R. Dietrich , Alexander Goldshmidt , Miya Howell , Kevin R. Kosola , Sivalinganna Manjunath , Anil Neelam , Linda Rymarquis , Thomas L. Slewinski , Tyamagondlu V. Venkatesh , Huai Wang
IPC: C12N15/82 , C12N15/113
Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through suppression, mutagenesis and/or editing of specific subtypes of GA20 or GA3 oxidase genes. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a GA oxidase gene are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
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7.发明申请公开(公告)号：US20180051295A1
公开(公告)日：2018-02-22
申请号：US15679699
申请日：2017-08-17
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Jayanand Boddu , Charles R. Dietrich , Alexander Goldshmidt , Miya Howell , Kevin R. Kosola , Anil Neelam , Thomas L. Slewinski , Tyamagondlu V. Venkatesh , Huai Wang
Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through suppression, mutagenesis and/or editing of specific subtypes of GA20 or GA3 oxidase genes. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a GA oxidase gene are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
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公开(公告)号：US20150166993A1
公开(公告)日：2015-06-18
申请号：US14567786
申请日：2014-12-11
Applicant: Monsanto Technology LLC
Inventor： Edwards M. Allen , Barry S. Goldman , Liang Guo , Sara E. Heisel , Shihshieh Huang , Sergey I. Ivashuta , David K. Kovalic , Elysia K. Krieger , James K. Roberts , Yuanji Zhang
IPC: C12N15/113 , C12N15/82
CPC classification number: C12N15/113 , C12N15/8216 , C12N15/8218 , C12N15/8238 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8279 , C12N15/8286 , C12N2310/141 , C12N2320/50 , Y02A40/146 , Y02A40/162
Abstract: This invention discloses novel microRNAs and their precursors, and recombinant DNA constructs including such novel miRNAs, miRNA precursors, miRNA promoters, and miRNA recognition sites corresponding to the miRNAs. Included are novel miRNA and miRNA precursors that exhibit nutrient-responsive expression. Also disclosed are miRNA decoy sequences. Further provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention and methods of controlling gene expression using recombinant DNA constructs of this invention.
Abstract translation: 本发明公开了新的微小RNA及其前体，以及重组DNA构建体，包括这样的新型miRNA，miRNA前体，miRNA启动子和对应于miRNA的miRNA识别位点。 包括显示营养反应表达的新型miRNA和miRNA前体。 还公开了miRNA诱饵序列。 还提供了非天然转基因植物细胞，植物和种子，在其基因组中含有本发明的重组DNA构建体和使用本发明的重组DNA构建体控制基因表达的方法。
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公开(公告)号：US20140317780A1
公开(公告)日：2014-10-23
申请号：US14191825
申请日：2014-02-27
Applicant: Monsanto Technology LLC
Inventor： Edwards M. Allen , Sara E. Heisel , Sergey Ivashuta , Elysia K. Krieger , Jennifer Lutke , Robert J. Meister , Yuanji Zhang
IPC: C12N15/82
CPC classification number: C12N15/8216 , C12N15/8217 , C12N15/8218 , C12N15/8234 , C12N15/8238 , C12N15/8254 , C12N15/8265 , C12N15/827 , C12N15/8275 , C12N15/8279 , C12N15/8285 , C12N15/8286 , C12N15/8289 , Y02A40/162 , Y02A40/164
Abstract: This invention provides molecular constructs and methods for the temporally specific control of gene expression in plants or in plant pests or pathogens. More specifically, this invention provides plant miRNA genes having novel circadian expression patterns that are useful for designing recombinant DNA constructs for temporally specific expression of at least one gene. Also provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention.
Abstract translation: 本发明提供用于在植物或植物害虫或病原体中时间特异性控制基因表达的分子构建体和方法。 更具体地，本发明提供具有新颖的昼夜节律表达模式的植物miRNA基因，其可用于设计用于至少一种基因的时间特异性表达的重组DNA构建体。 还提供了在其基因组中含有本发明的重组DNA构建体的非天然转基因植物细胞，植物和种子。
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公开(公告)号：US11319550B2
公开(公告)日：2022-05-03
申请号：US16847244
申请日：2020-04-13
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： Edwards M. Allen , Jayanand Boddu , Charles R. Dietrich , Alexander Goldshmidt , Miya Howell , Kevin R. Kosola , Anil Neelam , Thomas L. Slewinski , Tyamagondlu V. Venkatesh , Huai Wang , Sivalinganna Manjunath , Linda Rymarquis
IPC: C12N15/82
Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through suppression, mutagenesis and/or editing of specific subtypes of GA20 or GA3 oxidase genes. Modified plant cells and plants having a suppression element or mutation reducing the expression or activity of a GA oxidase gene are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
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