公开(公告)号：US20150035535A1

公开(公告)日：2015-02-05

申请号：US13957365

申请日：2013-08-01

申请人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

发明人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

IPC分类号： G01V3/12

CPC分类号： G01V3/12 ,  G01V3/28

摘要： An apparatus for making resistivity measurements near a drill bit includes a tool body, a transmitter deployed on the tool body, a receiver deployed on the tool body and at an axial distance from the transmitter, and a transmitting signal coupler coupled to the transmitter antenna and the receiver. The transmitter generates electrical signals and converts the electrical signals into electromagnetic signals to be transmitted. The receiver measures the amplitudes and phases of the electromagnetic signals received from the transmitter. The transmitting signal coupler couples a portion of the electrical signals from the transmitter antenna and measures the amplitudes and phases of the coupled electrical signals. Amplitude attenuation and phase shift between the electromagnetic signals received at the receiver and the electrical signals coupled at the transmitting signal coupler are computed for calculating resistivity.

摘要翻译： 用于在钻头附近进行电阻率测量的装置包括工具主体，布置在工具主体上的发射器，部署在工具主体上并且距离发射器轴向距离的接收器以及耦合到发射机天线的发射信号耦合器 收件人。 发射机产生电信号，并将电信号转换为要传输的电磁信号。 接收机测量从发射机接收的电磁信号的幅度和相位。 发射信号耦合器耦合来自发射机天线的电信号的一部分，并测量耦合的电信号的幅度和相位。 计算在接收机处接收的电磁信号与耦合在发射信号耦合器处的电信号之间的振幅衰减和相移，用于计算电阻率。

公开(公告)号：US20150028874A1

公开(公告)日：2015-01-29

申请号：US13949140

申请日：2013-07-23

申请人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

发明人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

IPC分类号： E21B49/00 ,  G01V3/20 ,  G01V3/34

CPC分类号： G01V3/20

摘要： An apparatus for making formation resistivity measurements near a drill bit includes a tool body, a toroidal antenna deployed on the tool body near the drill bit, a coupler coupled to the toroidal antenna, a transmitter circuit coupled with the toroidal antenna via the coupler to provide voltage signals to energize the toroidal antenna, a receiver circuit coupled with the toroidal antenna via the coupler to couple electrical current signals flowing in the toroidal antenna to the receiver circuit, and a controller and processor module coupled to the transmitter circuit and the receiver circuit to control the measurement operation and calculate formation resistivity. Formation resistivity is computed based on the voltage signals to energize the toroidal antenna and the measured electrical current signals flowing in the toroidal antenna. A corresponding method for making formation resistivity measurements near a drill bit is also provided.

摘要翻译： 用于在钻头附近进行地层电阻率测量的装置包括工具主体，在钻头附近部署在工具主体上的环形天线，耦合到环形天线的耦合器，经由耦合器与环形天线耦合的发射器电路，以提供 电压信号以激励环形天线，接收器电路经由耦合器与环形天线耦合以将在环形天线中流动的电流信号耦合到接收器电路，以及耦合到发射器电路和接收器电路的控制器和处理器模块 控制测量操作并计算地层电阻率。 基于电压信号计算形成电阻率，以激励环形天线和测量的在环形天线中流动的电流信号。 还提供了用于在钻头附近进行地层电阻率测量的相应方法。

公开(公告)号：US20140345944A1

公开(公告)日：2014-11-27

申请号：US14280195

申请日：2014-05-16

申请人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

发明人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

IPC分类号： E21B7/06 ,  E21B7/04

CPC分类号： E21B7/061 ,  E21B7/04 ,  E21B7/067 ,  E21B7/068 ,  E21B17/028 ,  E21B47/024

摘要： A rotary steerable drilling tool with an electromagnetic steering system can include a drill collar, a bit shaft, an orientation control module, a mud tube, a mud tube coupler, a universal joint, a mud sealing device, and a drill bit. The bit shaft can be mechanically coupled to the drill collar through the universal joint and the orientation control module and rotate about the universal joint. The orientation and the inclination angle of the bit shaft against the drill collar can be controlled by the orientation control module with the electromagnetic steering system. The orientation control module can include a guide track mounted on the inside wall of the drill collar, arrays of electromagnets mounted on the guide track, a positioning frame, a permanent magnet mounted on the positioning frame, a coupling tube, and at least two bearing wheels. A corresponding electromagnetic steering method is also provided.

摘要翻译： 具有电磁转向系统的旋转可转向钻具可以包括钻铤，钻头轴，定向控制模块，泥浆管，泥浆管联接器，万向接头，泥浆密封装置和钻头。 钻头轴可以通过万向接头和定向控制模块机械联接到钻铤，并围绕万向接头旋转。 钻头轴相对于钻铤的方向和倾斜角度可以由具有电磁转向系统的定向控制模块来控制。 定向控制模块可以包括安装在钻铤的内壁上的导轨，安装在导轨上的电磁体阵列，定位框架，安装在定位框架上的永磁体，联接管和至少两个轴承 车轮。 还提供了相应的电磁转向方法。

公开(公告)号：US20160356088A1

公开(公告)日：2016-12-08

申请号：US15243251

申请日：2016-08-22

申请人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

发明人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

IPC分类号： E21B7/06 ,  E21B47/024 ,  E21B17/02

CPC分类号： E21B7/061 ,  E21B7/04 ,  E21B7/062 ,  E21B7/067 ,  E21B7/068 ,  E21B17/028 ,  E21B47/024

摘要： A rotary steerable drilling tool with an electromagnetic steering system can include a drill collar, a bit shaft, an orientation control module, a mud tube, a mud tube coupler, a universal joint, a mud sealing device, and a drill bit. The bit shaft can be mechanically coupled to the drill collar through the universal joint and the orientation control module and rotate about the universal joint. The orientation and the inclination angle of the bit shaft against the drill collar can be controlled by the orientation control module with the electromagnetic steering system. The orientation control module can include a guide track mounted on the inside wall of the drill collar, arrays of electromagnets mounted on the guide track, a positioning frame, a permanent magnet mounted on the positioning frame, a coupling tube, and at least two bearing wheels. A corresponding electromagnetic steering method is also provided.

摘要翻译： 具有电磁转向系统的旋转可转向钻具可以包括钻铤，钻头轴，定向控制模块，泥浆管，泥浆管联接器，万向接头，泥浆密封装置和钻头。 钻头轴可以通过万向接头和定向控制模块机械联接到钻铤，并围绕万向接头旋转。 钻头轴相对于钻铤的方向和倾斜角度可以由具有电磁转向系统的定向控制模块来控制。 定向控制模块可以包括安装在钻铤的内壁上的导轨，安装在导轨上的电磁体阵列，定位框架，安装在定位框架上的永磁体，联接管和至少两个轴承 车轮。 还提供了相应的电磁转向方法。

公开(公告)号：US09447641B2

公开(公告)日：2016-09-20

申请号：US14280195

申请日：2014-05-16

申请人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

发明人： Naizhen Liu ,  Qihui Zhao ,  Yuzhou Lu ,  Yonghe Li ,  Rui Bai ,  Jing Li ,  Ce Liu

IPC分类号： E21B7/06 ,  E21B7/04 ,  E21B17/02 ,  E21B47/024

CPC分类号： E21B7/061 ,  E21B7/04 ,  E21B7/067 ,  E21B7/068 ,  E21B17/028 ,  E21B47/024

摘要： A rotary steerable drilling tool with an electromagnetic steering system can include a drill collar, a bit shaft, an orientation control module, a mud tube, a mud tube coupler, a universal joint, a mud sealing device, and a drill bit. The bit shaft can be mechanically coupled to the drill collar through the universal joint and the orientation control module and rotate about the universal joint. The orientation and the inclination angle of the bit shaft against the drill collar can be controlled by the orientation control module with the electromagnetic steering system. The orientation control module can include a guide track mounted on the inside wall of the drill collar, arrays of electromagnets mounted on the guide track, a positioning frame, a permanent magnet mounted on the positioning frame, a coupling tube, and at least two bearing wheels. A corresponding electromagnetic steering method is also provided.

摘要翻译： 具有电磁转向系统的旋转可转向钻具可以包括钻铤，钻头轴，定向控制模块，泥浆管，泥浆管联接器，万向接头，泥浆密封装置和钻头。 钻头轴可以通过万向接头和定向控制模块机械联接到钻铤，并围绕万向接头旋转。 钻头轴相对于钻铤的方向和倾斜角度可以由具有电磁转向系统的定向控制模块来控制。 定向控制模块可以包括安装在钻铤的内壁上的导轨，安装在导轨上的电磁体阵列，定位框架，安装在定位框架上的永磁体，联接管和至少两个轴承 车轮。 还提供了相应的电磁转向方法。

公开(公告)号：US11419431B2

公开(公告)日：2022-08-23

申请号：US16699365

申请日：2019-11-29

申请人： Yonghe Li

发明人： Yonghe Li

IPC分类号： A47C27/08

摘要： The present invention discloses an air bed including a mattress body formed by a top surface, a bottom surface and a side wall. The mattress body is provided with at least two layers of side walls being an inner side wall and an outer side wall respectively. The inside of the inner side wall forms a bed air chamber of the mattress body. A side wall air chamber of the mattress body is formed between the inner side wall and the outer side wall. The inside of the side wall air chamber between the inner side wall and the outer side wall is connected with a plurality of side wall drawstrings. The side wall drawstrings form a bed edge of the mattress body with the inner side wall, the outer side wall, and the side wall top surface/side wall bottom surface respectively.

公开(公告)号：US20080227698A1

公开(公告)日：2008-09-18

申请号：US11557292

申请日：2006-11-07

申请人： Guojun Bu ,  Yonghe Li

发明人： Guojun Bu ,  Yonghe Li

IPC分类号： A61K38/16 ,  C07K7/06 ,  C07K14/00 ,  C07K7/08 ,  C12N15/63 ,  A61P19/08 ,  A61P19/10 ,  A61K31/7052 ,  C12N5/00 ,  A61K38/08 ,  A61K38/10

CPC分类号： C07K14/51 ,  A61K38/00 ,  C07K14/47

摘要： Oligopeptides which can be used to treat bone disease such as osteoporosis are disclosed. Further disclosed are methods of treating bone disease such as osteoporosis. These methods include administration of a polypeptide encoded by the Mesd gene, or an oligopeptide comprising a contiguous subsequence of a Mesd polypeptide.

摘要翻译： 公开了可用于治疗骨疾病如骨质疏松症的寡肽。 进一步公开的是治疗骨疾病如骨质疏松症的方法。 这些方法包括施用由Mesd基因编码的多肽，或包含Mesd多肽的连续子序列的寡肽。

公开(公告)号：US08916607B2

公开(公告)日：2014-12-23

申请号：US13498272

申请日：2009-10-20

申请人： Huayin Wan ,  Rubing Li ,  Lijian Zhou ,  Tieqiu Liu ,  Yangshu Chen ,  Yonghe Li

发明人： Huayin Wan ,  Rubing Li ,  Lijian Zhou ,  Tieqiu Liu ,  Yangshu Chen ,  Yonghe Li

IPC分类号： A61K31/335 ,  A61K31/36 ,  A61K31/357

CPC分类号： A61K31/36 ,  A61K31/357

摘要： The present invention relates to the use of piperphentonamine or pharmaceutically acceptable salts thereof to prevent/treat encephalopathy in mammals, and the use of a combination of piperphentonamine or pharmaceutically acceptable salts thereof and other medicines in manufacture a medicine to prevent/treat encephalopathy in mammals. The mammals include human beings, and the encephalopathy includes cerebral injury related diseases or cerebrovascular diseases. The cerebrovascular diseases refer to cerebral ischemia, cerebral ischemia/reperfusion-induced injury or cerebral hemorrhage. The cerebral hemorrhage includes hypertensive cerebral hemorrhage, cerebral hemorrhage secondary to infarction, tumor cerebral hemorrhage or cerebral hemorrhage caused by arteritis. The cerebral ischemia means carotid system cerebral ischemia or vertebrobasilar cerebral ischemia.

摘要翻译： 本发明涉及哌酚苯胺或其药学上可接受的盐在哺乳动物中预防/治疗脑病的用途，以及在制备用于预防/治疗哺乳动物中的脑病的药物中使用胡椒胺或其药学上可接受的盐与其它药物的组合的用途。 哺乳动物包括人类，脑病包括脑损伤相关疾病或脑血管疾病。 脑血管疾病是指脑缺血，脑缺血/再灌注损伤或脑出血。 脑出血包括高血压性脑出血，继发于脑梗塞的脑出血，脑出血，脑动脉炎引起的脑出血。 脑缺血是指颈动脉系脑缺血或椎基底动脉脑缺血。

公开(公告)号：US20100197731A1

公开(公告)日：2010-08-05

申请号：US12598356

申请日：2007-01-31

申请人： Huayin Wan ,  Rubing Li ,  Yonghe Li ,  Lijian Zhou ,  Tieqiu Liu ,  Xiaohui Zhong

发明人： Huayin Wan ,  Rubing Li ,  Yonghe Li ,  Lijian Zhou ,  Tieqiu Liu ,  Xiaohui Zhong

IPC分类号： A61K31/445 ,  A61P9/00

CPC分类号： A61K31/36 ,  A61K9/0014 ,  A61K9/19 ,  A61K47/10 ,  A61K47/183 ,  A61K47/26 ,  C07D317/48

摘要： A kind of piperphentonamine hydrochloride lyophilized powder for injection and a preparation method thereof. The injection is prepared by one portion of piperphentonamine hydrochloride, 2.5-30 parts of excipient and 400-600 parts of water for injection with pH 1.5-5.5 via freeze-drying. The excipient is mannitol, dextran, lactose, saccharose, polyethylene glycol, poloxamer, glycine, etc.; It is preferred that the injection comprises one part of piperphentonamine hydrochloride, 10 parts of mannitol and 500 parts of water for injection with pH 2.0-3.0. The product is prepared by adding said piperphentonamine hydrochloride and excipient into water for injection, heating at 40° C.-90° C., ultrasonic dissolving, degerming, individually packing, pre-freezing and multistage drying, and packaging. Individually packing into a tubular glass bottle with brown color is preferred. The appearance, color & luster and solubility of the injection are excellent, the stability is good and with long storage period. The invention also provides the uses of the injection in the preparation of a medicament for treatment of heart failure and/or cardioprotection.

摘要翻译： 一种盐酸椒苯酮胺冻干粉末及其制备方法。 注射液由盐酸椒苯酮胺，2.5-30份赋形剂和400-600份注射用水通过冷冻干燥制备，pH为1.5-5.5。 赋形剂是甘露糖醇，葡聚糖，乳糖，蔗糖，聚乙二醇，泊洛沙姆，甘氨酸等; 注射剂优选包含一部分盐酸椒苯酮胺，10份甘露醇和500份注射用水，pH为2.0-3.0。 通过将所述盐酸椒苯酮胺和赋形剂加入注射用水中，在40℃〜90℃加热，超声溶解，除菌，单独包装，预冷冻和多级干燥以及包装，制备产品。 单独包装成棕色的管状玻璃瓶是首选。 注射剂的外观，颜色，光泽和溶解性优异，稳定性好，储存时间长。 本发明还提供了注射用于制备用于治疗心力衰竭和/或心脏保护的药物的用途。

公开(公告)号：US08513301B2

公开(公告)日：2013-08-20

申请号：US12598356

申请日：2007-01-31

申请人： Huayin Wan ,  Rubing Li ,  Yonghe Li ,  Lijian Zhou ,  Tieqiu Liu ,  Xiaohui Zhong

发明人： Huayin Wan ,  Rubing Li ,  Yonghe Li ,  Lijian Zhou ,  Tieqiu Liu ,  Xiaohui Zhong

IPC分类号： A61K31/36 ,  A61K31/445 ,  A61K9/00

CPC分类号： A61K31/36 ,  A61K9/0014 ,  A61K9/19 ,  A61K47/10 ,  A61K47/183 ,  A61K47/26 ,  C07D317/48

摘要： A kind of piperphentonamine hydrochloride lyophilized powder for injection and a preparation method thereof. The injection is prepared by one portion of piperphentonamine hydrochloride, 2.5-30 parts of excipient and 400-600 parts of water for injection with pH 1.5-5.5 via freeze-drying. The excipient is mannitol, dextran, lactose, saccharose, polyethylene glycol, poloxamer, glycine, etc.; It is preferred that the injection comprises one part of piperphentonamine hydrochloride, 10 parts of mannitol and 500 parts of water for injection with pH 2.0-3.0. The product is prepared by adding said piperphentonamine hydrochloride and excipient into water for injection, heating at 40° C.-90° C., ultrasonic dissolving, degerming, individually packing, pre-freezing and multistage drying, and packaging. Individually packing into a tubular glass bottle with brown color is preferred. The appearance, color & luster and solubility of the injection are excellent, the stability is good and with long storage period. The invention also provides the uses of the injection in the preparation of a medicament for treatment of heart failure and/or cardioprotection.

摘要翻译： 一种盐酸椒苯酮胺冻干粉末及其制备方法。 注射液由盐酸椒苯酮胺，2.5-30份赋形剂和400-600份注射用水通过冷冻干燥制备，pH为1.5-5.5。 赋形剂是甘露糖醇，葡聚糖，乳糖，蔗糖，聚乙二醇，泊洛沙姆，甘氨酸等; 注射剂优选包含一部分盐酸椒苯酮胺，10份甘露醇和500份注射用水，pH为2.0-3.0。 通过将所述盐酸椒苯酮胺和赋形剂加入注射用水中，在40℃〜90℃加热，超声溶解，除菌，单独包装，预冷冻和多级干燥以及包装，制备产品。 单独包装成棕色的管状玻璃瓶是首选。 注射剂的外观，颜色，光泽和溶解性优异，稳定性好，储存时间长。 本发明还提供了注射用于制备用于治疗心力衰竭和/或心脏保护的药物的用途。