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公开(公告)号：US09186843B2
公开(公告)日：2015-11-17
申请号：US14587932
申请日：2014-12-31
Applicant: NEXCELOM BIOSCIENCE LLC
Inventor： Leo L. Chan , Jean Qiu
IPC: G01N1/10 , B29C59/02 , B01L3/00 , B29C65/50 , B29C65/00 , G01N15/14 , G01N21/64 , G01N21/03 , B29L31/00 , B29C65/48 , B29K33/00 , B29K63/00 , B29K75/00
CPC classification number: B29C59/021 , B01L3/502707 , B01L2200/0689 , B01L2300/0877 , B01L2300/0887 , B29C65/4825 , B29C65/4835 , B29C65/5021 , B29C65/5057 , B29C66/1122 , B29C66/53461 , B29C66/71 , B29K2033/08 , B29K2063/00 , B29K2075/00 , B29L2031/756 , G01N15/14 , G01N15/1463 , G01N15/1484 , G01N21/03 , G01N21/6458 , G01N2015/1486 , G01N2201/02 , Y10T29/49826 , B29K2067/00 , B29K2069/00 , B29K2033/12 , B29K2025/06 , B29K2023/38
Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
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公开(公告)号：US20210069696A1
公开(公告)日：2021-03-11
申请号：US16963233
申请日：2019-02-21
Applicant: Nexcelom Bioscience LLC
Inventor： Peter Y. Li , Jean Qiu , Leo L. Chan , Justin R. Hascup , Timothy F. Smith , Todd R. Sobolewski , Nicholas N. Shaw
IPC: B01L3/00 , G01N33/487 , G01N15/14
Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
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公开(公告)号：US11911764B2
公开(公告)日：2024-02-27
申请号：US16963233
申请日：2019-02-21
Applicant: Nexcelom Bioscience LLC
Inventor： Peter Y. Li , Jean Qiu , Leo L. Chan , Justin R. Hascup , Timothy F. Smith , Todd R. Sobolewski , Nicholas N. Shaw
IPC: C12Q1/00 , B01L3/00 , G01N15/14 , G01N33/487 , G01N15/10
CPC classification number: B01L3/5085 , G01N15/147 , G01N33/4875 , B01L2200/10 , B01L2300/0654 , B01L2300/087 , B01L2300/0829 , G01N2015/1006 , G01N2015/1486
Abstract: The invention provides novel sample chambers, sample analysis units, multi-well plates, and imaging and analytical systems as well as methods for accurate, efficient and high-throughput imaging, measurement and analysis of diverse types of biological cells to obtain information such as cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
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公开(公告)号：US20160025710A1
公开(公告)日：2016-01-28
申请号：US14790482
申请日：2015-07-02
Applicant: NEXCELOM BIOSCIENCE LLC
Inventor： Leo L. Chan , Jean Qiu , Peter Li , Kevin Flanagan , Timothy Smith
CPC classification number: G01N33/5094 , G01N21/6428 , G01N21/6456 , G01N21/6486 , G06F19/26
Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods for internal calibration and focus reference for cytometry imaging.
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Patent Agency Ranking
公开(公告)号：US20220307966A1
公开(公告)日：2022-09-29
申请号：US17627630
申请日：2020-09-02
Applicant: Nexcelom Bioscience LLC
Inventor： Jean Qiu , Peter Y. Li , Leo L. Chan , Jordan Bell
Abstract: The invention provides novel sample chambers, units and multi-well plates, and systems and methods thereof, for built-in measurement assurance of cell counting methods and calibrated and/or quality-assured measurement and analysis of diverse types of biological cells, e.g., cell count, cell size, cell concentration, cell sub-population, cell morphology, cell viability, etc.
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公开(公告)号：US20180128717A1
公开(公告)日：2018-05-10
申请号：US15574857
申请日：2016-06-01
Applicant: Nexcelom Bioscience LLC
Inventor： Leo L. Chan , Jean Qiu , Peter Li , Olivier Déry , Sarah Kessel , Timothy Smith
CPC classification number: G01N1/30 , C12Q1/02 , G01N33/5005 , G01N33/52 , G01N2001/302
Abstract: The invention provides a method for accurate, efficient and high-throughout measurement of cell viability of diverse biological samples.
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公开(公告)号：US20180119195A1
公开(公告)日：2018-05-03
申请号：US15792572
申请日：2017-10-24
Applicant: Nexcelom Bioscience LLC
Inventor： Leo L. Chan , Jean Qiu , Peter Li , Kevin Flanagan
CPC classification number: C12Q1/02 , C12N1/16 , G01N15/1475 , G01N21/6428 , G01N21/6458 , G01N2015/0065 , G01N2015/0092 , G01N2015/1497 , G01N2021/6441 , G01N2333/395
Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
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公开(公告)号：US20150232906A1
公开(公告)日：2015-08-20
申请号：US14429878
申请日：2013-10-09
Applicant: NEXCELOM BIOSCIENCE LLC
Inventor： Leo L. Chan , Jean Qiu , Peter Li , Kevin Flanagan
CPC classification number: C12Q1/02 , C12N1/16 , G01N15/1475 , G01N21/6428 , G01N21/6458 , G01N2015/0065 , G01N2015/0092 , G01N2015/1497 , G01N2021/6441 , G01N2333/395
Abstract: The invention generally relates to analyzing yeast viability and reproduction rate of yeasts. More particularly, the invention relates to efficient and effective methods and compositions for accessing and measuring budding percentages, viability and concentration of yeast cells.
Abstract translation: 本发明一般涉及分析酵母存活率和酵母繁殖率。 更具体地，本发明涉及用于获取和测量酵母细胞的出芽百分比，活力和浓度的有效和有效的方法和组合物。
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公开(公告)号：US20150183153A1
公开(公告)日：2015-07-02
申请号：US14587932
申请日：2014-12-31
Applicant: NEXCELOM BIOSCIENCE LLC
Inventor： Leo L. Chan , Jean Qiu
CPC classification number: B29C59/021 , B01L3/502707 , B01L2200/0689 , B01L2300/0877 , B01L2300/0887 , B29C65/4825 , B29C65/4835 , B29C65/5021 , B29C65/5057 , B29C66/1122 , B29C66/53461 , B29C66/71 , B29K2033/08 , B29K2063/00 , B29K2075/00 , B29L2031/756 , G01N15/14 , G01N15/1463 , G01N15/1484 , G01N21/03 , G01N21/6458 , G01N2015/1486 , G01N2201/02 , Y10T29/49826 , B29K2067/00 , B29K2069/00 , B29K2033/12 , B29K2025/06 , B29K2023/38
Abstract: The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological sample. More particularly, the invention relates to a unique cell counting chamber, e.g., a thin gap fluidic cell chamber for both bright field and fluorescent imaging of bacteria or parasites, and methods for making the same.
Abstract translation: 本发明一般涉及用于分析和测量细胞和生物样品的分析和监测系统。 更具体地，本发明涉及一种独特的细胞计数室，例如用于细菌或寄生虫的亮场和荧光成像的薄间隙流体细胞室及其制备方法。
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